Page last updated: 2024-10-23

baclofen and Psychomotor Agitation

baclofen has been researched along with Psychomotor Agitation in 8 studies

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."7.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."5.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."3.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)
"The National institute on Alcohol Abuse and Alcoholism (NIAAA) considers alcohol abuse to be more than 14 units of alcohol a week for men and 7 units for women."2.82Baclofen to prevent agitation in alcohol-addicted patients in the ICU: study protocol for a randomised controlled trial. ( Asehnoune, K; Feuillet, F; Mahe, PJ; Sebille, V; Vourc'h, M, 2016)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."1.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"A patient with neuroleptic-induced akathisia was successfully treated with a combination of baclofen (a GABA agonist) and clonazepam (a serotonergic agent)."1.27Successful treatment of neuroleptic-induced akathisia with baclofen and clonazepam. A case report. ( Sandyk, R, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Vourc'h, M2
Garret, C1
Gacouin, A1
Lacherade, JC1
Jonas, M1
Klouche, K1
Ferrandiere, M1
Jaber, S1
Flet, L1
Dailly, E1
Pouplet, C1
Maamar, A1
Reignier, J1
Roquilly, A1
Feuillet, F2
Mahe, PJ2
Asehnoune, K2
Stratton, MS1
Staros, M1
Budefeld, T1
Searcy, BT1
Nash, C1
Eitel, C1
Carbone, D1
Handa, RJ1
Majdic, G1
Tobet, SA1
de Witte, LD1
Dekker, D1
Veraart, J1
Kromkamp, M1
Kaasjager, K1
Vinkers, CH1
Sebille, V1
Kailainathan, R1
Wong, A1
Greene, S1
Koutsogiannis, Z1
Salazar, ML1
Eiland, LS1
Pangilinan, PH1
Giacoletti-Argento, A1
Shellhaas, R1
Hurvitz, EA1
Hornyak, JE1
Sandyk, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU: Study Protocol for a Randomised Controlled Against Placebo Trial[NCT02723383]Phase 3314 participants (Actual)Interventional2016-06-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for baclofen and Psychomotor Agitation

ArticleYear
Neuropharmacology in pediatric brain injury: a review.
    PM & R : the journal of injury, function, and rehabilitation, 2010, Volume: 2, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Anticonvulsants; Antidepressive Agents; Antipsychotic Agent

2010

Trials

2 trials available for baclofen and Psychomotor Agitation

ArticleYear
Effect of High-Dose Baclofen on Agitation-Related Events Among Patients With Unhealthy Alcohol Use Receiving Mechanical Ventilation: A Randomized Clinical Trial.
    JAMA, 2021, 02-23, Volume: 325, Issue:8

    Topics: Adult; Aged; Alcohol-Induced Disorders; Alcoholism; Baclofen; Double-Blind Method; Female; GABA-B Re

2021
Baclofen to prevent agitation in alcohol-addicted patients in the ICU: study protocol for a randomised controlled trial.
    Trials, 2016, 08-19, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Alcoholism; Baclofen; Clinical Protocols; Double-Blind Method; Female; Huma

2016

Other Studies

5 other studies available for baclofen and Psychomotor Agitation

ArticleYear
Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Animals; Anxiety; Baclofen; Cell Movement; Depression; Embryo, Mammalian; Female; GABA-B Receptor An

2014
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
    Nederlands tijdschrift voor geneeskunde, 2016, Volume: 160

    Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans;

2016
Recognition of gamma-hydroxybutyric acid withdrawal: Rapid progression and prolonged symptomatology.
    Emergency medicine Australasia : EMA, 2017, Volume: 29, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Australia; Baclofen; Benzodiazepines; Diazepam; Humans; Hydroxybutyrat

2017
Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy.
    Pediatric emergency care, 2008, Volume: 24, Issue:10

    Topics: Abdominal Pain; Adolescent; Autonomic Dysreflexia; Baclofen; Cerebral Palsy; Diagnosis, Differential

2008
Successful treatment of neuroleptic-induced akathisia with baclofen and clonazepam. A case report.
    European neurology, 1985, Volume: 24, Issue:4

    Topics: Akathisia, Drug-Induced; Baclofen; Benzodiazepinones; Clonazepam; Haloperidol; Humans; Male; Middle

1985