Page last updated: 2024-10-23

baclofen and Parkinson Disease

baclofen has been researched along with Parkinson Disease in 9 studies

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"A new less invasive treatment of tremor using MR guided focused ultrasound has started and is promising."2.49[Role of neurosurgical management in movement disorders other than Parkinson disease]. ( Taira, T, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taira, T1
Hajj, R1
Milet, A1
Toulorge, D1
Cholet, N1
Laffaire, J1
Foucquier, J1
Robelet, S1
Mitry, R1
Guedj, M1
Nabirotchkin, S1
Chumakov, I1
Cohen, D1
Marsden, CD1
Sheehy, MP1
Moutoussis, M1
Orrell, W1
Volpi, R2
Chiodera, P2
Caffarra, P2
Scaglioni, A2
Saccani, A1
Coiro, V2
Lees, AJ2
Clarke, CR1
Harrison, MJ1
Shaw, KM1
Stern, GM1
Gerlach, J1
Marcato, A1
Rossi, G1
Caffarri, G1
Delsignore, R1

Reviews

1 review available for baclofen and Parkinson Disease

ArticleYear
[Role of neurosurgical management in movement disorders other than Parkinson disease].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Baclofen; Deep Brain Stimulation; Dystonia; Humans; Injections, Spinal; Movement Disorders; Muscle S

2013

Trials

3 trials available for baclofen and Parkinson Disease

ArticleYear
GABA and movement disorders.
    Advances in biochemical psychopharmacology, 1981, Volume: 30

    Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced;

1981
Different control mechanisms of growth hormone (GH) secretion between gamma-amino- and gamma-hydroxy-butyric acid: neuroendocrine evidence in Parkinson's disease.
    Psychoneuroendocrinology, 1997, Volume: 22, Issue:7

    Topics: Aged; Baclofen; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; M

1997
Baclofen in Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:8

    Topics: Aged; Aminobutyrates; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Indu

1978

Other Studies

5 other studies available for baclofen and Parkinson Disease

ArticleYear
Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson's disease.
    Scientific reports, 2015, Nov-06, Volume: 5

    Topics: Acamprosate; Animals; Baclofen; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine;

2015
Baclofen therapy for rigidity associated with Lewy body dementia.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 169, Issue:6

    Topics: Aged; Aged, 80 and over; Baclofen; Dementia; Female; GABA Agonists; Humans; Muscle Rigidity; Neurolo

1996
Hallucinations after withdrawal of baclofen.
    Lancet (London, England), 1977, Apr-16, Volume: 1, Issue:8016

    Topics: Aminobutyrates; Baclofen; Hallucinations; Humans; Male; Middle Aged; Parkinson Disease; Substance Wi

1977
The relationship between parkinsonism and tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Age Factors; Aminobutyrates; Baclofen; Basal Ganglia; Biperiden; Choline; Dopamine; Dyskinesia, Drug

1977
Failure of the gamma-aminobutyric acid (GABA) derivative, baclofen, to stimulate growth hormone secretion in Parkinson's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:4

    Topics: Aged; Baclofen; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Middle Aged; Parkinson Diseas

1991