Page last updated: 2024-10-23

baclofen and Paralysis

baclofen has been researched along with Paralysis in 13 studies

Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen therapy(ITB)is a recognized treatment for spastic paralysis."8.12[Intrathecal Baclofen Therapy for Spastic Paralysis]. ( Usami, K, 2022)
"Для поиска статей по теме обзора использовали базу данных PubMed и ключевые слова «cerebral palsy», «spasticity», «dystonia», «selective dorsal rhizotomy», «selective neurotomy», «intrathecal baclofen therapy», «spinal cord stimulation», «deep brain stimulation»."4.31[Methods and results of neurosurgical treatment of cerebral palsy]. ( Dekopov, AV; Isagulyan, ED; Tomsky, AA, 2023)
"Intrathecal baclofen therapy(ITB)is a recognized treatment for spastic paralysis."4.12[Intrathecal Baclofen Therapy for Spastic Paralysis]. ( Usami, K, 2022)
"Twenty patients with spinal spasticity caused by multiple sclerosis or spinal-cord injury who had had no response to treatment with oral baclofen received an intrathecal infusion of baclofen or saline for three days."2.66Intrathecal baclofen for severe spinal spasticity. ( Corcos, D; Gottlieb, G; Kroin, JS; Latash, M; Parke, B; Penn, RD; Savoy, SM, 1989)
"We share our experience of spasticity management with the ITB pump system in five patients at Vilnius University Hospital Santariskiu Klinikos."2.55Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania. ( Juocevicius, A; Kesiene, J; Kvascevicius, R; Lapteva, O; Mikulenaite, L; Raugalas, R; Rocka, S; Sipylaite, J; Vaitkus, A, 2017)
"Local spasticity can be treated with botulinum toxin injections."2.48Spasticity following spinal cord injury. ( Grønning, M; Hagen, EM; Rekand, T, 2012)
"These contractures were corrected sufficiently."1.28[Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma]. ( Frischhut, B; Saltuari, L, 1992)
"Twelve spastic patients received single oral doses of a new anti-spastic drug DS103-282 (Sandoz) 6 mg, baclofen 20 mg, and placebo on three separate days."1.26Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. ( Hassan, N; McLellan, DL, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Usami, K3
Dekopov, AV1
Tomsky, AA1
Isagulyan, ED1
Kvascevicius, R1
Lapteva, O1
Kesiene, J1
Vaitkus, A1
Mikulenaite, L1
Raugalas, R1
Sipylaite, J1
Rocka, S1
Juocevicius, A1
Thomas, CK1
Häger-Ross, CK1
Klein, CS1
Rekand, T1
Hagen, EM1
Grønning, M1
Taira, T1
Hassan, N1
McLellan, DL1
Soliman, IE1
Park, TS1
Berkelhamer, MC1
Rösche, J1
Saltuari, L1
Frischhut, B1
Meyerson, B1
Lind, G1
Linderoth, B1
Penn, RD1
Savoy, SM1
Corcos, D1
Latash, M1
Gottlieb, G1
Parke, B1
Kroin, JS1
Young, RR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury[NCT00223873]30 participants Interventional2002-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for baclofen and Paralysis

ArticleYear
Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2017, Volume: 78, Issue:3

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Epidural Abscess; Humans; Infusion Pumps, Implan

2017
Spasticity following spinal cord injury.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Apr-30, Volume: 132, Issue:8

    Topics: Administration, Oral; Baclofen; Botulinum Toxins; Critical Pathways; Humans; Infusions, Spinal; Inje

2012

Trials

2 trials available for baclofen and Paralysis

ArticleYear
Transient paralysis after intrathecal bolus of baclofen for the treatment of post-selective dorsal rhizotomy pain in children.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:5

    Topics: Analgesics, Opioid; Baclofen; Child, Preschool; Double-Blind Method; Female; Fentanyl; GABA Agonists

1999
Intrathecal baclofen for severe spinal spasticity.
    The New England journal of medicine, 1989, Jun-08, Volume: 320, Issue:23

    Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusion Pumps; Male

1989

Other Studies

9 other studies available for baclofen and Paralysis

ArticleYear
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Intrathecal Baclofen Therapy for Spastic Paralysis].
    No shinkei geka. Neurological surgery, 2022, Volume: 50, Issue:6

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis

2022
[Methods and results of neurosurgical treatment of cerebral palsy].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2023, Volume: 87, Issue:3

    Topics: Baclofen; Cerebral Palsy; Dystonia; Humans; Muscle Spasticity; Neurosurgical Procedures; Paralysis;

2023
Effects of baclofen on motor units paralysed by chronic cervical spinal cord injury.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 1

    Topics: Adult; Baclofen; Cervical Vertebrae; Chronic Disease; Electric Stimulation; Female; Humans; Male; Mi

2010
[Therapeutic methods for patients with spastic paralysis: recent progress].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Jul-10, Volume: 96, Issue:7

    Topics: Baclofen; Child; Female; Humans; Muscle Relaxants, Central; Muscle Spasticity; Paralysis; Peripheral

2007
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
    Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:12

    Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiple

1980
Treatment of spasticity.
    Spinal cord, 2002, Volume: 40, Issue:6

    Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cy

2002
[Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma].
    Der Orthopade, 1992, Volume: 21, Issue:5

    Topics: Anesthetics, Local; Baclofen; Brain Damage, Chronic; Brain Injuries; Catheters, Indwelling; Combined

1992
[Treatment of spasticity using an intrathecal infusion of baclofen].
    Lakartidningen, 1989, Nov-22, Volume: 86, Issue:47

    Topics: Adult; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged;

1989
Treatment of spastic paresis.
    The New England journal of medicine, 1989, Jun-08, Volume: 320, Issue:23

    Topics: Baclofen; Humans; Infusion Pumps; Muscle Spasticity; Paralysis; Spinal Cord Diseases; Subarachnoid S

1989