baclofen has been researched along with Paralysis in 13 studies
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecal baclofen therapy(ITB)is a recognized treatment for spastic paralysis." | 8.12 | [Intrathecal Baclofen Therapy for Spastic Paralysis]. ( Usami, K, 2022) |
| "Для поиска статей по теме обзора использовали базу данных PubMed и ключевые слова «cerebral palsy», «spasticity», «dystonia», «selective dorsal rhizotomy», «selective neurotomy», «intrathecal baclofen therapy», «spinal cord stimulation», «deep brain stimulation»." | 4.31 | [Methods and results of neurosurgical treatment of cerebral palsy]. ( Dekopov, AV; Isagulyan, ED; Tomsky, AA, 2023) |
| "Intrathecal baclofen therapy(ITB)is a recognized treatment for spastic paralysis." | 4.12 | [Intrathecal Baclofen Therapy for Spastic Paralysis]. ( Usami, K, 2022) |
| "Twenty patients with spinal spasticity caused by multiple sclerosis or spinal-cord injury who had had no response to treatment with oral baclofen received an intrathecal infusion of baclofen or saline for three days." | 2.66 | Intrathecal baclofen for severe spinal spasticity. ( Corcos, D; Gottlieb, G; Kroin, JS; Latash, M; Parke, B; Penn, RD; Savoy, SM, 1989) |
| "We share our experience of spasticity management with the ITB pump system in five patients at Vilnius University Hospital Santariskiu Klinikos." | 2.55 | Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania. ( Juocevicius, A; Kesiene, J; Kvascevicius, R; Lapteva, O; Mikulenaite, L; Raugalas, R; Rocka, S; Sipylaite, J; Vaitkus, A, 2017) |
| "Local spasticity can be treated with botulinum toxin injections." | 2.48 | Spasticity following spinal cord injury. ( Grønning, M; Hagen, EM; Rekand, T, 2012) |
| "These contractures were corrected sufficiently." | 1.28 | [Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma]. ( Frischhut, B; Saltuari, L, 1992) |
| "Twelve spastic patients received single oral doses of a new anti-spastic drug DS103-282 (Sandoz) 6 mg, baclofen 20 mg, and placebo on three separate days." | 1.26 | Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. ( Hassan, N; McLellan, DL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Usami, K | 3 |
| Dekopov, AV | 1 |
| Tomsky, AA | 1 |
| Isagulyan, ED | 1 |
| Kvascevicius, R | 1 |
| Lapteva, O | 1 |
| Kesiene, J | 1 |
| Vaitkus, A | 1 |
| Mikulenaite, L | 1 |
| Raugalas, R | 1 |
| Sipylaite, J | 1 |
| Rocka, S | 1 |
| Juocevicius, A | 1 |
| Thomas, CK | 1 |
| Häger-Ross, CK | 1 |
| Klein, CS | 1 |
| Rekand, T | 1 |
| Hagen, EM | 1 |
| Grønning, M | 1 |
| Taira, T | 1 |
| Hassan, N | 1 |
| McLellan, DL | 1 |
| Soliman, IE | 1 |
| Park, TS | 1 |
| Berkelhamer, MC | 1 |
| Rösche, J | 1 |
| Saltuari, L | 1 |
| Frischhut, B | 1 |
| Meyerson, B | 1 |
| Lind, G | 1 |
| Linderoth, B | 1 |
| Penn, RD | 1 |
| Savoy, SM | 1 |
| Corcos, D | 1 |
| Latash, M | 1 |
| Gottlieb, G | 1 |
| Parke, B | 1 |
| Kroin, JS | 1 |
| Young, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury[NCT00223873] | 30 participants | Interventional | 2002-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for baclofen and Paralysis
| Article | Year |
|---|---|
Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Epidural Abscess; Humans; Infusion Pumps, Implan | 2017 |
Spasticity following spinal cord injury.
Topics: Administration, Oral; Baclofen; Botulinum Toxins; Critical Pathways; Humans; Infusions, Spinal; Inje | 2012 |
2 trials available for baclofen and Paralysis
| Article | Year |
|---|---|
Transient paralysis after intrathecal bolus of baclofen for the treatment of post-selective dorsal rhizotomy pain in children.
Topics: Analgesics, Opioid; Baclofen; Child, Preschool; Double-Blind Method; Female; Fentanyl; GABA Agonists | 1999 |
Intrathecal baclofen for severe spinal spasticity.
Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusion Pumps; Male | 1989 |
9 other studies available for baclofen and Paralysis
| Article | Year |
|---|---|
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Intrathecal Baclofen Therapy for Spastic Paralysis].
Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Paralysis | 2022 |
[Methods and results of neurosurgical treatment of cerebral palsy].
Topics: Baclofen; Cerebral Palsy; Dystonia; Humans; Muscle Spasticity; Neurosurgical Procedures; Paralysis; | 2023 |
Effects of baclofen on motor units paralysed by chronic cervical spinal cord injury.
Topics: Adult; Baclofen; Cervical Vertebrae; Chronic Disease; Electric Stimulation; Female; Humans; Male; Mi | 2010 |
[Therapeutic methods for patients with spastic paralysis: recent progress].
Topics: Baclofen; Child; Female; Humans; Muscle Relaxants, Central; Muscle Spasticity; Paralysis; Peripheral | 2007 |
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiple | 1980 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cy | 2002 |
[Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma].
Topics: Anesthetics, Local; Baclofen; Brain Damage, Chronic; Brain Injuries; Catheters, Indwelling; Combined | 1992 |
[Treatment of spasticity using an intrathecal infusion of baclofen].
Topics: Adult; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; | 1989 |
Treatment of spastic paresis.
Topics: Baclofen; Humans; Infusion Pumps; Muscle Spasticity; Paralysis; Spinal Cord Diseases; Subarachnoid S | 1989 |