Page last updated: 2024-10-23

baclofen and Obesity

baclofen has been researched along with Obesity in 6 studies

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Although the anti-obesity effects of baclofen in the present study were mild, this pilot study suggests the possibility that baclofen might serve as a new anti-obesity drug in humans."9.14Positive effect of baclofen on body weight reduction in obese subjects: a pilot study. ( Arima, H; Oiso, Y, 2010)
"Although the anti-obesity effects of baclofen in the present study were mild, this pilot study suggests the possibility that baclofen might serve as a new anti-obesity drug in humans."5.14Positive effect of baclofen on body weight reduction in obese subjects: a pilot study. ( Arima, H; Oiso, Y, 2010)
" In BED with obesity or overweight, bupropion may cause mild weight loss without seizures, and chromium may improve glucose regulation."4.91Psychopharmacologic treatment of eating disorders: emerging findings. ( Guerdjikova, AI; Keck, PE; McElroy, SL; Mori, N, 2015)
" Minute ventilation (Ve), tidal volume (Vt), and breathing frequency (f) during room air breathing and in response to 10 min of hypercapnia (8% CO(2)) and 30 min of hypoxia (10% O(2)) were measured by the barometric method, and peak oxygen consumption (Vo(2 peak)) was measured by an enclosed metabolic treadmill following the randomized blinded subcutaneous administration of equal volumes of DMSO (vehicle), bicuculline (selective GABA(A) receptor antagonist, 1 mg/kg), and phaclofen (selective GABA(B) receptor antagonist, 1 mg/kg)."3.74GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats. ( Chen, JS; Huang, CY; Lee, SD; Lo, MJ; Ting, H; Yang, AL, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Sun, R1
Tsunekawa, T1
Hirose, T1
Yaginuma, H1
Taki, K1
Mizoguchi, A1
Miyata, T1
Kobayashi, T1
Sugiyama, M1
Onoue, T1
Takagi, H1
Hagiwara, D1
Ito, Y1
Iwama, S1
Suga, H1
Banno, R2
Bettler, B1
Arima, H3
McElroy, SL1
Guerdjikova, AI1
Mori, N1
Keck, PE1
Oiso, Y2
Yang, AL1
Lo, MJ1
Ting, H1
Chen, JS1
Huang, CY1
Lee, SD1
Sato, I1
Ozaki, N2
Watanabe, M1
Goto, M1
Shimizu, H1
Hayashi, M1
Nagasaki, H1
Abramson, SI1
Holmes, AA1
Hagberg, CA1

Reviews

1 review available for baclofen and Obesity

ArticleYear
Psychopharmacologic treatment of eating disorders: emerging findings.
    Current psychiatry reports, 2015, Volume: 17, Issue:5

    Topics: Administration, Intranasal; Anorexia Nervosa; Anti-Obesity Agents; Antidepressive Agents, Second-Gen

2015

Trials

1 trial available for baclofen and Obesity

ArticleYear
Positive effect of baclofen on body weight reduction in obese subjects: a pilot study.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:19

    Topics: Adiponectin; Adult; Animals; Anti-Obesity Agents; Appetite; Baclofen; Blood Glucose; Blood Pressure;

2010

Other Studies

4 other studies available for baclofen and Obesity

ArticleYear
GABA
    Scientific reports, 2021, 09-29, Volume: 11, Issue:1

    Topics: Animals; Baclofen; Bulimia; Diet, High-Fat; Disease Models, Animal; Dopaminergic Neurons; Female; GA

2021
GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:1

    Topics: Animals; Baclofen; Bicuculline; Dimethyl Sulfoxide; GABA Antagonists; Hypercapnia; Hypoxia; Male; Ob

2007
Peripherally administered baclofen reduced food intake and body weight in db/db as well as diet-induced obese mice.
    FEBS letters, 2007, Oct-16, Volume: 581, Issue:25

    Topics: Adipokines; Adipose Tissue, White; Administration, Oral; Animals; Anti-Obesity Agents; Arcuate Nucle

2007
Awake insertion of the Bonfils Retromolar Intubation Fiberscope in five patients with anticipated difficult airways.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Accidents, Traffic; Adult; Aged; Baclofen; Body Size; Cervical Vertebrae; Equipment Design; Fiber Op

2008