baclofen has been researched along with Myoclonic Jerk in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In male Swiss mice, muscimol produced myoclonic jerks." | 7.66 | Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981) |
| "This suggests that patients with polymyoclonus and ataxia, no matter what the etiology, may benefit from the use of baclofen." | 5.29 | Baclofen in the treatment of polymyoclonus and ataxia in a patient with homocystinuria. ( Awaad, Y; Fish, I; Kyriakakos, A; Moroney, J; Sansaricq, C; Snyderman, SE, 1995) |
| "We report a case of spinal myoclonus induced by the tip of an intrathecal catheter in a 35-year-old patient with severe, adult-onset, generalized dystonia of unknown cause, treated for 2 years using intrathecal baclofen." | 3.69 | Spinal myoclonus induced by an intrathecal catheter. ( Ford, B; Goodman, R; Khandji, A; Pullman, SL, 1997) |
| "In male Swiss mice, muscimol produced myoclonic jerks." | 3.66 | Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981) |
| "A case of post-anoxic action myoclonus is reported in which a very good control of the myoclonic jerks was achieved with levodopa, gaba and bacoflen, while the antiepileptic drugs did not seem to be useful." | 3.66 | Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs. ( Coletti, A; Mandelli, A; Minoli, G; Tredici, G, 1980) |
| " They also required higher doses and more rapid dosage increases." | 2.68 | Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus. ( Dressnandt, J; Marquardt, G; Mauch, E; Meinck, HM; Müller-Schwefe, G; Rieke, K; Schumm, F; Stayer, C; Tronnier, V, 1997) |
| "Five patients with nocturnal myoclonus (periodic leg movements during sleep), mean age 59." | 2.65 | Effect of baclofen on sleep-related periodic leg movements. ( Flagg, W; Guilleminault, C, 1984) |
| "However, unusual symptoms such as myoclonus can occur in few cases and together with the rarity of the condition, the prevalence of misdiagnosis is high." | 1.51 | Stiff limb syndrome with lower limb myoclonus: A case report. ( Chen, J; Feng, YY; Li, LL; Zhang, CG, 2019) |
| "A case of severe action myoclonus after pulmonary arrest is described." | 1.48 | Treatment of Postanoxic Action Myoclonus With Intrathecal Baclofen: A Case Report. ( Dumigan, RW; Whitlock, JA, 2018) |
| "Two patients with spinal myoclonus who required the use of an assistive device because of difficulty walking resulting in falls." | 1.38 | Intrathecal baclofen for the treatment of spinal myoclonus: a case series. ( Chiodo, AE; Saval, A, 2012) |
| "Acquired pendular nystagmus (APN) occurs with multiple sclerosis (MS) and oculopalatal tremor (OPT); distinct features of the nystagmus have led to the development of separate models for their pathogenesis." | 1.37 | Pharmacological tests of hypotheses for acquired pendular nystagmus. ( Leigh, RJ; Optican, LM; Shaikh, AG; Thurtell, MJ, 2011) |
| "The very rare case of palatal myoclonus manifesting in objective tinnitus was discussed." | 1.31 | [A case of objective tinnitus caused by palatal myoclonus]. ( Nowak, K; Szyfter, W, 2001) |
| "For treatment of opioid-induced myoclonus a dose reduction or a change of the opioid should be considered as well as symptomatic treatment with benzodiazepines or baclofen." | 1.30 | [Myoclonus resulting from high-dose epidural and intravenous morphine infusion]. ( Grond, S; Radbruch, L; Zech, D, 1997) |
| "Propriospinal myoclonus is a subtype of spinal myoclonus characterized by axial flexion or extension jerks, arrhythmic and prolonged muscle bursts with a pattern of activation consistent with a slow conduction within the propriospinal pathways." | 1.30 | [Propriospinal myoclonus induced by relaxation and drowsiness]. ( Arné, P; Dousset, V; Henry, P; Paty, J; Tison, F, 1998) |
| "This suggests that patients with polymyoclonus and ataxia, no matter what the etiology, may benefit from the use of baclofen." | 1.29 | Baclofen in the treatment of polymyoclonus and ataxia in a patient with homocystinuria. ( Awaad, Y; Fish, I; Kyriakakos, A; Moroney, J; Sansaricq, C; Snyderman, SE, 1995) |
| " The following were taken as evaluation criteria: age, sex, performance status, duration and dosage of previous systemic and current spinal morphine therapy, concomitant analgesic and co-analgesic medication, pretreatment of the dorsal column and neurological dysfunction due to damage either of the nerval plexus or of the medulla spinalis." | 1.29 | Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking. ( Bingel, U; Kloke, M; Seeber, S, 1994) |
| "Oral treatment with baclofen and sodium valproate was partially successful in one patient, but ineffective in the other." | 1.29 | Propriospinal myoclonus in tetraplegic patients: clinical, electrophysiological and therapeutic aspects. ( Alaoui, P; Arné, P; Barat, M; Fouillet, N; Petit, H; Wiart, L, 1995) |
| "A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve." | 1.26 | Jerking stiff-man syndrome. ( Alberca, R; Chaparro, J; Romero, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, CG | 1 |
| Li, LL | 1 |
| Feng, YY | 1 |
| Chen, J | 1 |
| Maharaj, S | 1 |
| Seegobin, K | 1 |
| Bajric, B | 1 |
| Chang, S | 1 |
| Whitlock, JA | 1 |
| Dumigan, RW | 1 |
| Birthi, P | 1 |
| Walters, C | 1 |
| Ortiz Vargas, O | 1 |
| Karandikar, N | 1 |
| Shaikh, AG | 1 |
| Thurtell, MJ | 1 |
| Optican, LM | 1 |
| Leigh, RJ | 1 |
| Quiñones Ortiz, L | 1 |
| Suárez Laurés, A | 1 |
| Pobes Martínez, A | 1 |
| de la Torre, M | 1 |
| Torres Lacalle, A | 1 |
| Forascepi Roza, R | 1 |
| Ruiz-Roso, G | 1 |
| Gomis, A | 1 |
| Fernández-Lucas, M | 1 |
| Díaz-Domínguez, M | 1 |
| Teruel-Briones, JL | 1 |
| Quereda, C | 1 |
| Chiodo, AE | 1 |
| Saval, A | 1 |
| Ray, BK | 1 |
| Guha, G | 1 |
| Misra, AK | 1 |
| Das, SK | 1 |
| Kraemer, M | 1 |
| Berlit, P | 1 |
| Menon, MK | 2 |
| Vivonia, CA | 1 |
| Coletti, A | 1 |
| Mandelli, A | 1 |
| Minoli, G | 1 |
| Tredici, G | 1 |
| Guilleminault, C | 1 |
| Flagg, W | 1 |
| Alberca, R | 1 |
| Romero, M | 1 |
| Chaparro, J | 1 |
| Awaad, Y | 1 |
| Sansaricq, C | 1 |
| Moroney, J | 1 |
| Fish, I | 1 |
| Kyriakakos, A | 1 |
| Snyderman, SE | 1 |
| Kloke, M | 1 |
| Bingel, U | 1 |
| Seeber, S | 1 |
| Fouillet, N | 1 |
| Wiart, L | 1 |
| Arné, P | 2 |
| Alaoui, P | 1 |
| Petit, H | 1 |
| Barat, M | 1 |
| Radbruch, L | 1 |
| Zech, D | 1 |
| Grond, S | 1 |
| Ford, B | 1 |
| Pullman, SL | 1 |
| Khandji, A | 1 |
| Goodman, R | 1 |
| Stayer, C | 1 |
| Tronnier, V | 1 |
| Dressnandt, J | 1 |
| Mauch, E | 1 |
| Marquardt, G | 1 |
| Rieke, K | 1 |
| Müller-Schwefe, G | 1 |
| Schumm, F | 1 |
| Meinck, HM | 1 |
| Kriem, B | 1 |
| Cagniard, B | 1 |
| Bouquet, C | 1 |
| Rostain, JC | 1 |
| Abraini, JH | 1 |
| Tison, F | 1 |
| Dousset, V | 1 |
| Paty, J | 1 |
| Henry, P | 1 |
| Nowak, K | 1 |
| Szyfter, W | 1 |
| Meldrum, BS | 1 |
| Goulon, M | 1 |
| Nouailhat, F | 1 |
| Escourolle, R | 1 |
| Zarranz-Imirizaldu, JJ | 1 |
| Grosbuis, S | 1 |
| Lévy-Alcover, MA | 1 |
| Nugent, S | 1 |
| Katz, MD | 1 |
| Little, TE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Periodic Leg Movement's Diagnosis in Spinal Cord Injury: Actigraphy as an Alternative for Polysomnography?[NCT04618978] | 160 participants (Anticipated) | Interventional | 2021-02-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for baclofen and Myoclonic Jerk
| Article | Year |
|---|---|
Effect of baclofen on sleep-related periodic leg movements.
Topics: Aged; Baclofen; Electroencephalography; Female; Humans; Leg; Male; Middle Aged; Muscle Contraction; | 1984 |
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.
Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Cohort Studies; Disease Progression; Female; | 1997 |
25 other studies available for baclofen and Myoclonic Jerk
| Article | Year |
|---|---|
Stiff limb syndrome with lower limb myoclonus: A case report.
Topics: Baclofen; Botulinum Toxins, Type A; Diagnosis, Differential; Electromyography; Humans; Immunoglobuli | 2019 |
Myoclonus as a late manifestation of West Nile disease.
Topics: Aged; Anticonvulsants; Baclofen; Confusion; Electroencephalography; Humans; Lorazepam; Magnetic Reso | 2017 |
Treatment of Postanoxic Action Myoclonus With Intrathecal Baclofen: A Case Report.
Topics: Baclofen; Brain Infarction; Heart Arrest; Humans; Infusion Pumps, Implantable; Injections, Spinal; M | 2018 |
The use of intrathecal baclofen therapy for myoclonus in a patient with Lance Adams syndrome.
Topics: Accidents, Traffic; Adult; Baclofen; Humans; Hypoxia; Injections, Spinal; Male; Muscle Relaxants, Ce | 2011 |
Pharmacological tests of hypotheses for acquired pendular nystagmus.
Topics: Amines; Baclofen; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Eye Movements; Gabapentin; gamma-A | 2011 |
Warning against unexpected medication in haemodialysis.
Topics: Acyclovir; Aged; Akathisia, Drug-Induced; Alcoholic Intoxication; Baclofen; Continuity of Patient Ca | 2011 |
Aciclovir and valaciclovir neurotoxicity in patients with renal failure.
Topics: Acyclovir; Akathisia, Drug-Induced; Baclofen; Continuity of Patient Care; Humans; Kidney Failure, Ch | 2012 |
Intrathecal baclofen for the treatment of spinal myoclonus: a case series.
Topics: Adult; Baclofen; Female; Humans; Injections, Spinal; Middle Aged; Muscle Relaxants, Central; Myoclon | 2012 |
Involuntary jerking of lower half of the body (spinal myoclonus).
Topics: Baclofen; Clonazepam; Clonidine; Diagnosis, Differential; Humans; Lower Extremity; Middle Aged; Myoc | 2005 |
Progressive encephalomyelitis with rigidity and myoclonus in an 81-year-old patient.
Topics: Aged, 80 and over; Anti-Inflammatory Agents; Baclofen; Electromyography; Encephalomyelitis; Female; | 2008 |
Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Male; Mice; Muscimol; | 1981 |
Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs.
Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hypox | 1980 |
Jerking stiff-man syndrome.
Topics: Adult; Baclofen; Diazepam; Female; Humans; Muscle Rigidity; Myoclonus; Spasm | 1982 |
Possible value of baclofen in myoclonus.
Topics: Animals; Baclofen; Humans; Mice; Myoclonus | 1980 |
Baclofen in the treatment of polymyoclonus and ataxia in a patient with homocystinuria.
Topics: Adult; Baclofen; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Drug Administration | 1995 |
Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking.
Topics: Administration, Oral; Analgesia; Analgesia, Epidural; Baclofen; Clonazepam; Female; Humans; Infusion | 1994 |
Propriospinal myoclonus in tetraplegic patients: clinical, electrophysiological and therapeutic aspects.
Topics: Adult; Baclofen; Electromyography; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Myoc | 1995 |
[Myoclonus resulting from high-dose epidural and intravenous morphine infusion].
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Baclofen; Female; GABA Agonists; Humans; Injections, | 1997 |
Spinal myoclonus induced by an intrathecal catheter.
Topics: Adult; Baclofen; Catheterization; Dystonia; Electromyography; Female; Humans; Injections, Spinal; Mu | 1997 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium | 1998 |
[Propriospinal myoclonus induced by relaxation and drowsiness].
Topics: Anticonvulsants; Baclofen; Clonazepam; Electrophysiology; Female; Humans; Middle Aged; Muscle Relaxa | 1998 |
[A case of objective tinnitus caused by palatal myoclonus].
Topics: Baclofen; Child; Humans; Male; Muscle Relaxants, Central; Myoclonus; Tinnitus | 2001 |
Gamma-aminobutyric acid and the search for new anticonvulsant drugs.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Aminobutyrates; Animals; Anticonvulsants; Ba | 1978 |
[Methyl bromide poisoning. 3 cases, 1 fatal. Neruopathological study of one case of coma with myoclonus followed for 5 years].
Topics: Adolescent; Adult; Baclofen; Cerebellum; Cerebral Cortex; Chlormethiazole; Clonazepam; Coma; Cortica | 1975 |
Baclofen overdose with cardiac conduction abnormalities: case report and review of the literature.
Topics: Adult; Baclofen; Bradycardia; Female; Heart Conduction System; Humans; Myoclonus; Receptors, GABA-A; | 1986 |