baclofen has been researched along with Muscle Rigidity in 26 studies
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Baclofen, 90 mg daily, was given to a patient with stiff-man syndrome diagnosed by electromyography and clinical criteria." | 7.66 | Baclofen in the treatment of stiff-man syndrome. ( Korsvik, H; Miller, F, 1981) |
| "A 69-year-old woman with a history of hemodialysis-dependent end-stage renal disease presented to the Emergency Department with encephalopathy, ataxia, and dystonia after the addition of a recent baclofen prescription for back pain (10 mg twice daily)." | 3.85 | Baclofen Toxicity in a Patient with Hemodialysis-Dependent End-Stage Renal Disease. ( Katz, KD; Merrick, SS; Porter, LM, 2017) |
| "To test the efficacy of intrathecal baclofen in various movement disorders, 18 patients with dystonia, head trauma, cerebral palsy, rigidity, or painful spasms underwent a trial of intrathecal baclofen." | 3.69 | Intrathecal baclofen for motor disorders. ( Gianino, JM; Penn, RD; York, MM, 1995) |
| "Baclofen, 90 mg daily, was given to a patient with stiff-man syndrome diagnosed by electromyography and clinical criteria." | 3.66 | Baclofen in the treatment of stiff-man syndrome. ( Korsvik, H; Miller, F, 1981) |
| " They also required higher doses and more rapid dosage increases." | 2.68 | Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus. ( Dressnandt, J; Marquardt, G; Mauch, E; Meinck, HM; Müller-Schwefe, G; Rieke, K; Schumm, F; Stayer, C; Tronnier, V, 1997) |
| "We concur with the concept that neuroleptic malignant syndrome represents a spectrum of disorders, and add it to the list of possible sequelae after abrupt withdrawal of baclofen." | 2.41 | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. ( Gainsborough, N; Turner, MR, 2001) |
| "However, unusual symptoms such as myoclonus can occur in few cases and together with the rarity of the condition, the prevalence of misdiagnosis is high." | 1.51 | Stiff limb syndrome with lower limb myoclonus: A case report. ( Chen, J; Feng, YY; Li, LL; Zhang, CG, 2019) |
| "These patients suffered from spasticity due to many different diseases." | 1.38 | Intrathecal baclofen therapy for severe spasticity: analysis on a series of 112 consecutive patients and future prospectives. ( Mirone, G; Moraci, A; Natale, M; Rotondo, M, 2012) |
| "baclofen treatment also decreased, where after 5 days of baclofen infusion 1." | 1.33 | Development of baclofen tolerance in a rat model of chronic spasticity and rigidity. ( Fuchigami, T; Hefferan, MP; Marsala, M, 2006) |
| "Transient spinal cord ischemia may lead to a progressive degeneration of spinal interneurons and subsequently to increased hind limb motor tone." | 1.33 | Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study. ( Galik, J; Hefferan, MP; Kakinohana, M; Kakinohana, O; Marsala, J; Marsala, M; Nakamura, S; Tomori, Z; Yaksh, TL, 2006) |
| "Diazepam was without effect on the extensor reflex in spinal rats." | 1.27 | Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant. ( Furukawa, K; Hori, M; Ito, T; Kadokawa, T; Karasawa, T, 1985) |
| "A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve." | 1.26 | Jerking stiff-man syndrome. ( Alberca, R; Chaparro, J; Romero, M, 1982) |
| "Spasms are increased by Chlorimipramine which may by used as a provocative test in uncertain cases." | 1.26 | [The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)]. ( Heckl, R; Stöhr, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, CG | 1 |
| Li, LL | 1 |
| Feng, YY | 1 |
| Chen, J | 1 |
| Saigal, R | 1 |
| Goyal, L | 1 |
| Yadav, R | 1 |
| Agrawal, A | 1 |
| Mital, P | 1 |
| Patel, B | 1 |
| Porter, LM | 1 |
| Merrick, SS | 1 |
| Katz, KD | 1 |
| Natale, M | 1 |
| Mirone, G | 1 |
| Rotondo, M | 1 |
| Moraci, A | 1 |
| Puccioni-Sohler, M | 1 |
| Papais-Alvarenga, R | 1 |
| de Souza, PM | 1 |
| de França, SC | 1 |
| Gonçalves, RR | 1 |
| Jacobson, S | 1 |
| Marsala, M | 3 |
| Hefferan, MP | 3 |
| Kakinohana, O | 2 |
| Nakamura, S | 2 |
| Marsala, J | 2 |
| Tomori, Z | 2 |
| Fuchigami, T | 1 |
| Kakinohana, M | 1 |
| Galik, J | 1 |
| Yaksh, TL | 1 |
| Kraemer, M | 1 |
| Berlit, P | 1 |
| Pirovino, M | 1 |
| Meier, J | 1 |
| Meyer, M | 1 |
| Waldmeier, P | 1 |
| Schmid, M | 1 |
| Kawajiri, S | 1 |
| Kojima, H | 1 |
| Akashi, A | 1 |
| Alberca, R | 1 |
| Romero, M | 1 |
| Chaparro, J | 1 |
| Miller, F | 1 |
| Korsvik, H | 1 |
| Whelan, JL | 1 |
| Penn, RD | 2 |
| Gianino, JM | 1 |
| York, MM | 1 |
| Moutoussis, M | 1 |
| Orrell, W | 1 |
| Stayer, C | 1 |
| Tronnier, V | 1 |
| Dressnandt, J | 1 |
| Mauch, E | 1 |
| Marquardt, G | 1 |
| Rieke, K | 1 |
| Müller-Schwefe, G | 1 |
| Schumm, F | 1 |
| Meinck, HM | 1 |
| Turner, MR | 1 |
| Gainsborough, N | 1 |
| Gouider-Khouja, N | 1 |
| Mekaouar, A | 1 |
| Larnaout, A | 1 |
| Miladi, N | 1 |
| Ben Khelifa, F | 1 |
| Hentati, F | 1 |
| Fukuda, H | 1 |
| Stöhr, M | 1 |
| Heckl, R | 1 |
| Calne, DB | 1 |
| Blum, P | 1 |
| Jankovic, J | 1 |
| Kroin, JS | 1 |
| Watanabe, K | 1 |
| Ito, T | 1 |
| Hori, M | 1 |
| Furukawa, K | 1 |
| Karasawa, T | 1 |
| Kadokawa, T | 1 |
4 reviews available for baclofen and Muscle Rigidity
| Article | Year |
|---|---|
Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen.
Topics: Adult; Baclofen; Creatine Kinase; Electrocardiography; Humans; Male; Muscle Relaxants, Central; Musc | 2001 |
Drug treatment of spasticity and rigidity.
Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; P | 1975 |
Stiff-person syndrome: an autoimmune disease.
Topics: Autoantibodies; Autoimmune Diseases; Baclofen; Diazepam; Drug Administration Schedule; Drug Therapy, | 1991 |
[The stiff-man syndrome].
Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid | 1987 |
1 trial available for baclofen and Muscle Rigidity
| Article | Year |
|---|---|
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.
Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Cohort Studies; Disease Progression; Female; | 1997 |
21 other studies available for baclofen and Muscle Rigidity
| Article | Year |
|---|---|
Stiff limb syndrome with lower limb myoclonus: A case report.
Topics: Baclofen; Botulinum Toxins, Type A; Diagnosis, Differential; Electromyography; Humans; Immunoglobuli | 2019 |
Stiff Person Syndrome.
Topics: Adult; Antibodies; Anticonvulsants; Autoimmunity; Baclofen; Clonazepam; Electromyography; Glutamate | 2015 |
Baclofen Toxicity in a Patient with Hemodialysis-Dependent End-Stage Renal Disease.
Topics: Aged; Ataxia; Back Pain; Baclofen; Brain Diseases; Confusion; Dystonia; Emergency Service, Hospital; | 2017 |
Intrathecal baclofen therapy for severe spasticity: analysis on a series of 112 consecutive patients and future prospectives.
Topics: Adolescent; Adult; Baclofen; Child; Consciousness Disorders; Disabled Persons; Dose-Response Relatio | 2012 |
Parkinsonism in the course of HTLV-I-associated myelopathy.
Topics: Antiparkinson Agents; Baclofen; Blotting, Western; Electromyography; Enzyme-Linked Immunosorbent Ass | 2005 |
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter.
Topics: Anesthetics, Inhalation; Animals; Baclofen; Chronic Disease; Electromyography; Halothane; Injections | 2005 |
Development of baclofen tolerance in a rat model of chronic spasticity and rigidity.
Topics: Animals; Baclofen; Chronic Disease; Drug Tolerance; GABA-A Receptor Agonists; Injections, Spinal; Is | 2006 |
Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study.
Topics: Acetyltransferases; Analysis of Variance; Animals; Baclofen; Dose-Response Relationship, Radiation; | 2006 |
Progressive encephalomyelitis with rigidity and myoclonus in an 81-year-old patient.
Topics: Aged, 80 and over; Anti-Inflammatory Agents; Baclofen; Electromyography; Encephalomyelitis; Female; | 2008 |
[Malignant neuroleptics syndrome].
Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal | 1984 |
[A comparison of the effects of baclofen and some other muscle relaxants on alpha-rigidity in rats].
Topics: Animals; Baclofen; Brain Ischemia; Chlordiazepoxide; Dantrolene; Decerebrate State; Diazepam; Male; | 1984 |
Jerking stiff-man syndrome.
Topics: Adult; Baclofen; Diazepam; Female; Humans; Muscle Rigidity; Myoclonus; Spasm | 1982 |
Baclofen in the treatment of stiff-man syndrome.
Topics: Aged; Baclofen; Female; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome | 1981 |
Baclofen in treatment of the 'stiff-man' syndrome.
Topics: Adult; Baclofen; Diazepam; Drug Therapy, Combination; Humans; Male; Muscle Rigidity; Spasm | 1980 |
Intrathecal baclofen for motor disorders.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Craniocerebral Trauma; Dystonia; Female; Humans; Inject | 1995 |
Baclofen therapy for rigidity associated with Lewy body dementia.
Topics: Aged; Aged, 80 and over; Baclofen; Dementia; Female; GABA Agonists; Humans; Muscle Rigidity; Neurolo | 1996 |
Progressive encephalomyelitis with rigidity presenting as a stiff-person syndrome.
Topics: Anti-Inflammatory Agents; Baclofen; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; El | 2002 |
[Effects of diazepam and baclofen on the anemic decerebrate rigidity in rats (author's transl)].
Topics: Aminooxyacetic Acid; Animals; Baclofen; Brain; Decerebrate State; Depression, Chemical; Diazepam; Di | 1979 |
[The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)].
Topics: Aged; Baclofen; Clomipramine; Clonazepam; Female; Humans; Muscle Rigidity; Muscles; Reaction Time; S | 1977 |
Continuous intrathecal baclofen for severe spasticity.
Topics: Adult; Baclofen; Female; Humans; Infusions, Parenteral; Middle Aged; Muscle Rigidity; Muscle Spastic | 1985 |
Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant.
Topics: Animals; Arousal; Baclofen; Behavior, Animal; Cats; Decerebrate State; Diazepam; Electroencephalogra | 1985 |