Page last updated: 2024-10-23

baclofen and Movement Disorders

baclofen has been researched along with Movement Disorders in 23 studies

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen reduces spasticity in individuals with cerebral palsy."8.79Intrathecal baclofen in cerebral palsy movement disorders. ( Albright, AL, 1996)
"The aim of this retrospective analysis was to determine the impact of intrathecal baclofen (ITB) therapy on motor function in patients with cerebral palsy (CP)."7.77Intrathecal baclofen and motor function in cerebral palsy. ( Antonello, CE; Motta, F; Stignani, C, 2011)
"For spinal spasticity, they are typically in the order of 100-300 μg/day."5.42Intrathecal Baclofen therapy in Germany: Proceedings of the IAB-Interdisciplinary Working Group for Movement Disorders Consensus Meeting. ( Berweck, S; Chatzikalfas, A; Dressler, D; Ebke, M; Frank, B; Hesse, S; Huber, M; Krauss, JK; Mücke, KH; Nolte, A; Oelmann, HD; Pickenbrock, H; Saberi, FA; Schmutzler, M; Schönle, PW; Van der Ven, C; Veelken, N; Vogel, M; Vogt, T, 2015)
"Treatment of children with movement disorders associated with CP increased slowly in the 1970s and 1980s but accelerated rapidly in the 1990s with the introduction of lumbar dorsal rhizotomies and intrathecal baclofen."5.41Spasticity and movement disorders in cerebral palsy. ( Albright, AL, 2023)
"Intrathecal baclofen reduces spasticity in individuals with cerebral palsy."4.79Intrathecal baclofen in cerebral palsy movement disorders. ( Albright, AL, 1996)
"The aim of this retrospective analysis was to determine the impact of intrathecal baclofen (ITB) therapy on motor function in patients with cerebral palsy (CP)."3.77Intrathecal baclofen and motor function in cerebral palsy. ( Antonello, CE; Motta, F; Stignani, C, 2011)
"To test the efficacy of intrathecal baclofen in various movement disorders, 18 patients with dystonia, head trauma, cerebral palsy, rigidity, or painful spasms underwent a trial of intrathecal baclofen."3.69Intrathecal baclofen for motor disorders. ( Gianino, JM; Penn, RD; York, MM, 1995)
"Baclofen is a GABA-like drug which passes through the blood-brain barrier and which reduces the neuroleptic-induced increase of dopamine turn-over."2.64Baclofen (Lioresal) in the treatment ofneuroleptic-induced tardive dyskinesia. ( Korsgaard, S, 1976)
"A new less invasive treatment of tremor using MR guided focused ultrasound has started and is promising."2.49[Role of neurosurgical management in movement disorders other than Parkinson disease]. ( Taira, T, 2013)
"Children with primary dystonia and those with tremor can be treated with deep brain stimulation of the internal globus pallidus and thalamus, respectively."2.42Neurosurgical treatment of spasticity and other pediatric movement disorders. ( Albright, AL, 2003)
"For spinal spasticity, they are typically in the order of 100-300 μg/day."1.42Intrathecal Baclofen therapy in Germany: Proceedings of the IAB-Interdisciplinary Working Group for Movement Disorders Consensus Meeting. ( Berweck, S; Chatzikalfas, A; Dressler, D; Ebke, M; Frank, B; Hesse, S; Huber, M; Krauss, JK; Mücke, KH; Nolte, A; Oelmann, HD; Pickenbrock, H; Saberi, FA; Schmutzler, M; Schönle, PW; Van der Ven, C; Veelken, N; Vogel, M; Vogt, T, 2015)
"Central pontine and extrapontine myelinolysis (CPEM) are rare conditions usually associated with rapid correction of hyponatremia."1.34Psychotic disorder in a patient with central and extrapontine myelinolysis. ( Krystal, A; Lim, L, 2007)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's2 (8.70)18.2507
2000's7 (30.43)29.6817
2010's7 (30.43)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Albright, AL3
Assumpcao de Monaco, B1
Fruett da Costa, PR1
Franceschini, PR1
Lake, W1
Shah, H1
Taira, T1
Dressler, D1
Berweck, S1
Chatzikalfas, A1
Ebke, M1
Frank, B1
Hesse, S1
Huber, M1
Krauss, JK1
Mücke, KH1
Nolte, A1
Oelmann, HD1
Schönle, PW1
Schmutzler, M1
Pickenbrock, H1
Van der Ven, C1
Veelken, N1
Vogel, M1
Vogt, T1
Saberi, FA1
Faller, KM1
Quintana, RG1
Fernández-Alvarez, E1
Lundy, C1
Lumsden, D1
Fairhurst, C1
Benecke, R1
Patejdl, R1
Krach, L1
Motta, F1
Antonello, CE1
Stignani, C1
Nomura, S1
Kagawa, Y1
Kida, H1
Maruta, Y1
Imoto, H1
Fujii, M1
Suzuki, M1
Turner, MS1
Roubertie, A1
Leydet, J1
Rivier, F1
Humbertclaude, V1
Cheminal, R1
Echenne, B1
Lim, L1
Krystal, A1
Marsden, CD1
Sheehy, MP1
Kirubakaran, V1
Mayfield, D1
Rengachary, S1
Penn, RD1
Gianino, JM1
York, MM1
Korsgaard, S1
Tourian, A2
Iacono, R1
Nashold, B1
Urban, B1
Sanders, D1
Iacono, RP1
Linford, J1
Sandyk, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pros and Cons of Botulinum Injection Treatment in Cerebral Palsy: A Qualitative Study Examining the Caregiver's Perspectives[NCT04256187]21 participants (Actual)Observational2019-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for baclofen and Movement Disorders

ArticleYear
Spasticity and movement disorders in cerebral palsy.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023, Volume: 39, Issue:10

    Topics: Baclofen; Cerebral Palsy; Child; Dystonia; Humans; Movement Disorders; Muscle Relaxants, Central; Mu

2023
Intrathecal Baclofen Infusion for the Treatment of Movement Disorders.
    Neurosurgery clinics of North America, 2019, Volume: 30, Issue:2

    Topics: Baclofen; Humans; Injections, Spinal; Movement Disorders; Muscle Relaxants, Central; Treatment Outco

2019
[Role of neurosurgical management in movement disorders other than Parkinson disease].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Baclofen; Deep Brain Stimulation; Dystonia; Humans; Injections, Spinal; Movement Disorders; Muscle S

2013
Movement disorders in children: recent advances in management.
    Indian journal of pediatrics, 2009, Volume: 76, Issue:5

    Topics: Age Distribution; Age of Onset; Baclofen; Benzodiazepines; Child; Child, Preschool; Cholinergic Anta

2009
Treating complex movement disorders in children with cerebral palsy.
    The Ulster medical journal, 2009, Volume: 78, Issue:3

    Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Deep Brain Stimulation; Humans; Infusion Pumps, Implanta

2009
[New therapies for spastic movement disorders].
    MMW Fortschritte der Medizin, 2009, Volume: 151 Suppl 3

    Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans;

2009
Neurosurgical treatment of spasticity and other pediatric movement disorders.
    Journal of child neurology, 2003, Volume: 18 Suppl 1

    Topics: Athetosis; Baclofen; Child; Chorea; Dystonia; Electric Stimulation Therapy; GABA Agonists; Humans; I

2003
Intrathecal drug delivery 2002.
    Acta neurochirurgica. Supplement, 2003, Volume: 87

    Topics: Baclofen; Drug Approval; Humans; Infusion Pumps, Implantable; Injections, Spinal; Morphine; Movement

2003
[Movement disorders in childhood: therapeutic update].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2004, Volume: 11, Issue:8

    Topics: Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins, Type A; Child; Consensus; Electric Stimulation T

2004
Intrathecal baclofen in cerebral palsy movement disorders.
    Journal of child neurology, 1996, Volume: 11 Suppl 1

    Topics: Baclofen; Cerebral Palsy; Health Care Costs; Humans; Infusion Pumps, Implantable; Injections, Spinal

1996

Trials

2 trials available for baclofen and Movement Disorders

ArticleYear
GABA and movement disorders.
    Advances in biochemical psychopharmacology, 1981, Volume: 30

    Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced;

1981
Baclofen (Lioresal) in the treatment ofneuroleptic-induced tardive dyskinesia.
    Acta psychiatrica Scandinavica, 1976, Volume: 54, Issue:1

    Topics: Aged; Aminobutyrates; Baclofen; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Middle Ag

1976

Other Studies

11 other studies available for baclofen and Movement Disorders

ArticleYear
Intracerebroventricular baclofen therapy improves function and quality of life in a child with severe cerebral palsy.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023, Volume: 39, Issue:12

    Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Movement Disorders; Muscle Rel

2023
Intrathecal Baclofen therapy in Germany: Proceedings of the IAB-Interdisciplinary Working Group for Movement Disorders Consensus Meeting.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:11

    Topics: Baclofen; Germany; Humans; Infusion Pumps, Implantable; Injections, Spinal; Movement Disorders; Musc

2015
Movement disorder in young weimaraners.
    The Veterinary record, 2016, Jan-02, Volume: 178, Issue:1

    Topics: Age of Onset; Animals; Baclofen; Diazepam; Dog Diseases; Dogs; Movement Disorders; Quality of Life;

2016
Intrathecal baclofen and motor function in cerebral palsy.
    Developmental medicine and child neurology, 2011, Volume: 53, Issue:5

    Topics: Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Movement Disorders

2011
Intrathecal baclofen and motor function in cerebral palsy.
    Developmental medicine and child neurology, 2011, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Age Factors; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disability Evalua

2011
Effects of intrathecal baclofen therapy on motor and cognitive functions in a rat model of cerebral palsy.
    Journal of neurosurgery. Pediatrics, 2012, Volume: 9, Issue:2

    Topics: Animals; Animals, Newborn; Baclofen; Cerebral Palsy; Cognition Disorders; Electric Stimulation; Evok

2012
Psychotic disorder in a patient with central and extrapontine myelinolysis.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antiparkinson Agents; Antipsychotic Agents; Baclofen; Fema

2007
Dyskinesia and psychosis in a patient following baclofen withdrawal.
    The American journal of psychiatry, 1984, Volume: 141, Issue:5

    Topics: Adult; Baclofen; Humans; Male; Movement Disorders; Muscle Spasticity; Pain; Paraplegia; Psychoses, S

1984
Intrathecal baclofen for motor disorders.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Craniocerebral Trauma; Dystonia; Female; Humans; Inject

1995
Involuntary movements of the lower extremity following dorsal root entry zone lesions in a man treated for phantom limb pain.
    Applied neurophysiology, 1988, Volume: 51, Issue:2-5

    Topics: Baclofen; Humans; Leg; Male; Middle Aged; Movement Disorders; Phantom Limb; Spinal Nerve Roots

1988
Baclofen in the treatment of post-amputation autonomous stump movements.
    European neurology, 1987, Volume: 26, Issue:3

    Topics: Amputation, Surgical; Baclofen; Humans; Male; Middle Aged; Movement Disorders; Postoperative Complic

1987