baclofen has been researched along with Motor Neuron Disease in 14 studies
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to present a case of deep vein thrombosis (DVT) and pulmonary embolism (PE) after an intrathecal baclofen bolus test." | 7.74 | Intrathecal baclofen bolus complicated by deep vein thrombosis and pulmonary embolism. A case report. ( Carda, S; Cazzaniga, M; Pozzi, R; Taiana, C, 2008) |
| "The aim of this study was to present a case of deep vein thrombosis (DVT) and pulmonary embolism (PE) after an intrathecal baclofen bolus test." | 3.74 | Intrathecal baclofen bolus complicated by deep vein thrombosis and pulmonary embolism. A case report. ( Carda, S; Cazzaniga, M; Pozzi, R; Taiana, C, 2008) |
| "In the spinal spasticity which is characterized by spasms, the Spasm Frequency Scale is useful in order to monitor their frequency." | 2.44 | Intrathecal baclofen therapy in patients with severe spasticity. ( Bramanti, P; D'Aleo, G; Di Bella, P; Marra, GA, 2007) |
| "All patients reported improvement in spasticity as measured by clinical examinations and Ashworth scores; 1/5 had complications with the pump related to migration of catheter." | 1.62 | Utility of intrathecal baclofen pump in primary lateral sclerosis. ( Patwa, HS; Raymond, M; Zubair, AS, 2021) |
| "Baclofen was weaned down and switched to intrathecal ziconotide at 0." | 1.51 | Low-Dose Intrathecal Ziconotide for Spasticity From Primary Lateral Sclerosis: A Case Report. ( Goldstein, RB; Kohan, LR; Zhu, X, 2019) |
| "These contractures were corrected sufficiently." | 1.28 | [Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma]. ( Frischhut, B; Saltuari, L, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Zubair, AS | 1 |
| Raymond, M | 1 |
| Patwa, HS | 1 |
| Shuja, A | 1 |
| Deutch, A | 1 |
| Saulino, M | 1 |
| Zhu, X | 1 |
| Kohan, LR | 1 |
| Goldstein, RB | 1 |
| Rauf, J | 1 |
| Akhtar, J | 1 |
| Khealani, BA | 1 |
| Ali, L | 1 |
| Sgouros, S | 1 |
| Seri, S | 1 |
| Milano, JB | 1 |
| Neto, MC | 1 |
| Hunhevicz, SC | 1 |
| Arruda, WO | 1 |
| Ramina, R | 1 |
| Barros, E | 1 |
| Marra, GA | 1 |
| D'Aleo, G | 1 |
| Di Bella, P | 1 |
| Bramanti, P | 1 |
| Rietman, JS | 1 |
| Geertzen, JH | 1 |
| Carda, S | 1 |
| Cazzaniga, M | 1 |
| Taiana, C | 1 |
| Pozzi, R | 1 |
| Zed, PJ | 1 |
| Stiver, HG | 1 |
| Devonshire, V | 1 |
| Jewesson, PJ | 1 |
| Marra, F | 1 |
| Elovic, E | 1 |
| Marquardt, G | 1 |
| Seifert, V | 1 |
| Saltuari, L | 1 |
| Frischhut, B | 1 |
4 reviews available for baclofen and Motor Neuron Disease
| Article | Year |
|---|---|
Intrathecal Therapies.
Topics: Adult; Baclofen; Female; Humans; Injections, Spinal; Male; Motor Neuron Disease; Muscle Relaxants, C | 2018 |
Intrathecal baclofen therapy in patients with severe spasticity.
Topics: Animals; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Motor Neur | 2007 |
Efficacy of intrathecal baclofen delivery in the management of severe spasticity in upper motor neuron syndrome.
Topics: Baclofen; Drug Delivery Systems; Humans; Injections, Spinal; Motor Neuron Disease; Muscle Relaxants, | 2007 |
Principles of pharmaceutical management of spastic hypertonia.
Topics: Anti-Dyskinesia Agents; Baclofen; Benzodiazepines; Botulinum Toxins; Brain Injuries; Clonidine; Dant | 2001 |
1 trial available for baclofen and Motor Neuron Disease
| Article | Year |
|---|---|
The effect of intrathecal baclofen on muscle co-contraction in children with spasticity of cerebral origin.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Electromyography; Female; Follow-Up Studies; Humans; In | 2002 |
9 other studies available for baclofen and Motor Neuron Disease
| Article | Year |
|---|---|
Utility of intrathecal baclofen pump in primary lateral sclerosis.
Topics: Baclofen; Humans; Injections, Spinal; Middle Aged; Motor Neuron Disease; Muscle Relaxants, Central; | 2021 |
An incidental finding of a baclofen pump catheter-related colon perforation diagnosed a during routine screening colonoscopy.
Topics: Baclofen; Catheters; Colon, Descending; Colonoscopy; Female; Humans; Incidental Findings; Intestinal | 2018 |
Low-Dose Intrathecal Ziconotide for Spasticity From Primary Lateral Sclerosis: A Case Report.
Topics: Adult; Baclofen; Female; Humans; Injections, Spinal; Motor Neuron Disease; Muscle Spasticity; omega- | 2019 |
Peripheral (limb) myokymic discharges in motor neuron disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Baclofen; Deltoid Muscle; Directive | 2012 |
Intrathecal baclofen for spasticity in primary lateral sclerosis.
Topics: Aged; Baclofen; Follow-Up Studies; Humans; Injections, Spinal; Male; Motor Neuron Disease; Muscle Re | 2005 |
Intrathecal baclofen bolus complicated by deep vein thrombosis and pulmonary embolism. A case report.
Topics: Aged; Baclofen; Diagnosis, Differential; Echocardiography; Female; Humans; Injections; Motor Neuron | 2008 |
Continuous intrathecal pump infusion of baclofen with antibiotic drugs for treatment of pump-associated meningitis. Case report.
Topics: Adult; Anti-Bacterial Agents; Baclofen; Dose-Response Relationship, Drug; Drug Therapy, Combination; | 2000 |
Use of intrathecal baclofen for treatment of spasticity in amyotrophic lateral sclerosis.
Topics: Adult; Baclofen; Follow-Up Studies; Humans; Injections, Spinal; Male; Motor Neuron Disease; Muscle S | 2002 |
[Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma].
Topics: Anesthetics, Local; Baclofen; Brain Damage, Chronic; Brain Injuries; Catheters, Indwelling; Combined | 1992 |