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baclofen and Minimally Conscious State

baclofen has been researched along with Minimally Conscious State in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Baclofen is mainly an antispastic drug and the main indication of ITB is generalized lower limb spasticity in spinal cord injury and multiple sclerosis."6.44Intrathecal baclofen in the treatment of spasticity, dystonia and vegetative disorders. ( Menei, P; Richard, I, 2007)
"Sporadic cases of dramatic recovery from persistent vegetative state after intrathecal administration of baclofen have been reported."6.44Intrathecal baclofen in the treatment of post-stroke central pain, dystonia, and persistent vegetative state. ( Hori, T; Taira, T, 2007)
"Baclofen is also used for control of dystonia due to cerebral palsy or reflex sympathetic dystrophy."6.42Clinical application of drug pump for spasticity, pain, and restorative neurosurgery: other clinical applications of intrathecal baclofen. ( Hori, T; Taira, T, 2003)
"Baclofen (Lioresal) is a drug of choice to treat spasticity and is increasingly being administered intrathecally via an implantable pump in cases refractory to oral therapy."5.32Intrathecal baclofen withdrawal mimicking sepsis. ( Amin, Y; Kao, LW; Kirk, MA; Turner, MS, 2003)
"Baclofen is mainly an antispastic drug and the main indication of ITB is generalized lower limb spasticity in spinal cord injury and multiple sclerosis."2.44Intrathecal baclofen in the treatment of spasticity, dystonia and vegetative disorders. ( Menei, P; Richard, I, 2007)
"Sporadic cases of dramatic recovery from persistent vegetative state after intrathecal administration of baclofen have been reported."2.44Intrathecal baclofen in the treatment of post-stroke central pain, dystonia, and persistent vegetative state. ( Hori, T; Taira, T, 2007)
"Baclofen is also used for control of dystonia due to cerebral palsy or reflex sympathetic dystrophy."2.42Clinical application of drug pump for spasticity, pain, and restorative neurosurgery: other clinical applications of intrathecal baclofen. ( Hori, T; Taira, T, 2003)
"Unexpectedly, one emerged from the minimally conscious state and the other from post-traumatic amnesia."1.42Influence of intrathecal baclofen on the level of consciousness and mental functions after extremely severe traumatic brain injury: brief report. ( Al-Khodairy, AT; Nicolo, D; Vuadens, P; Wicky, G, 2015)
" The severity of spasticity as a consequence of brain injury can change during years and it is necessery to follow it with dosage and dynamics of baclofen therapy."1.38[Results of intrathecal baclofen therapy on spasticity in patients with brain injury]. ( Both, B; Dénes, Z; Klauber, A; Lóránd, E, 2012)
"Sporadic cases of recovery from persistent vegetative state (PVS) after administration of intrathecal baclofen (ITB) have been reported without giving any possible explanation for its paradoxical effect."1.35Intrathecal baclofen in patients with persistent vegetative state: 2 hypotheses. ( Govoni, S; Mura, E; Onorati, P; Pistoia, F; Sarà, M, 2009)
"Patients in persistent vegetative state (PVS) usually have diffuse and widespread damage to the brain, spasticity is generally seen in such patients."1.35Intrathecal administration of GABA agonists in the vegetative state. ( Taira, T, 2009)
"Baclofen (Lioresal) is a drug of choice to treat spasticity and is increasingly being administered intrathecally via an implantable pump in cases refractory to oral therapy."1.32Intrathecal baclofen withdrawal mimicking sepsis. ( Amin, Y; Kao, LW; Kirk, MA; Turner, MS, 2003)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Khodairy, AT1
Wicky, G1
Nicolo, D1
Vuadens, P1
Lanzillo, B1
Loreto, V1
Calabrese, C1
Estraneo, A1
Moretta, P1
Trojano, L1
Sarà, M2
Pistoia, F1
Mura, E1
Onorati, P2
Govoni, S1
Taira, T3
Clauss, RP1
Georgiopoulos, M1
Katsakiori, P1
Kefalopoulou, Z1
Ellul, J1
Chroni, E1
Constantoyannis, C1
Dénes, Z1
Klauber, A1
Both, B1
Lóránd, E1
Kao, LW1
Amin, Y1
Kirk, MA1
Turner, MS1
Hori, T2
Atiyeh, BS1
Hayek, SN1
Skaff, GS1
Araj, AM1
Chamoun, RB1
Sacco, S1
Cipolla, F1
Scoppetta, C1
Albertini, G1
Carolei, A1
Richard, I1
Menei, P1

Reviews

4 reviews available for baclofen and Minimally Conscious State

ArticleYear
Vegetative state and minimally conscious state: a review of the therapeutic interventions.
    Stereotactic and functional neurosurgery, 2010, Volume: 88, Issue:4

    Topics: Baclofen; Consciousness; Electric Stimulation Therapy; Humans; Persistent Vegetative State; Pyridine

2010
Clinical application of drug pump for spasticity, pain, and restorative neurosurgery: other clinical applications of intrathecal baclofen.
    Acta neurochirurgica. Supplement, 2003, Volume: 87

    Topics: Baclofen; Cerebrovascular Circulation; Dystonia; Electric Stimulation Therapy; Humans; Infusion Pump

2003
Intrathecal baclofen in the treatment of spasticity, dystonia and vegetative disorders.
    Acta neurochirurgica. Supplement, 2007, Volume: 97, Issue:Pt 1

    Topics: Baclofen; Dystonia; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Persis

2007
Intrathecal baclofen in the treatment of post-stroke central pain, dystonia, and persistent vegetative state.
    Acta neurochirurgica. Supplement, 2007, Volume: 97, Issue:Pt 1

    Topics: Baclofen; Dystonia; Humans; Muscle Relaxants, Central; Pain; Persistent Vegetative State; Stroke

2007

Other Studies

9 other studies available for baclofen and Minimally Conscious State

ArticleYear
Influence of intrathecal baclofen on the level of consciousness and mental functions after extremely severe traumatic brain injury: brief report.
    Brain injury, 2015, Volume: 29, Issue:4

    Topics: Adult; Baclofen; Brain Injuries; Consciousness; Humans; Male; Mental Processes; Middle Aged; Muscle

2015
Does pain relief influence recovery of consciousness? A case report of a patient treated with ziconotide.
    European journal of physical and rehabilitation medicine, 2016, Volume: 52, Issue:2

    Topics: Adult; Analgesics, Non-Narcotic; Baclofen; Brain Injuries, Traumatic; Humans; Male; Muscle Relaxants

2016
Intrathecal baclofen in patients with persistent vegetative state: 2 hypotheses.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:7

    Topics: Adult; Baclofen; Consciousness; Female; Humans; Injections, Spinal; Male; Middle Aged; Muscle Relaxa

2009
Intrathecal administration of GABA agonists in the vegetative state.
    Progress in brain research, 2009, Volume: 177

    Topics: Adolescent; Baclofen; Child; GABA Agents; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male;

2009
Neurotransmitters in coma, vegetative and minimally conscious states, pharmacological interventions.
    Medical hypotheses, 2010, Volume: 75, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Baclofen; Coma; Dopamine Agents; GABA Agonists; gamma-Aminobutyric

2010
[Results of intrathecal baclofen therapy on spasticity in patients with brain injury].
    Ideggyogyaszati szemle, 2012, Jul-30, Volume: 65, Issue:7-8

    Topics: Adult; Baclofen; Brain Injuries; Drug Administration Schedule; Female; Humans; Hungary; Infusion Pum

2012
Intrathecal baclofen withdrawal mimicking sepsis.
    The Journal of emergency medicine, 2003, Volume: 24, Issue:4

    Topics: Baclofen; Child, Preschool; Clinical Protocols; Decerebrate State; Diagnosis, Differential; Emergenc

2003
Salvage of baclofen pump pocket infection with muscle flap.
    Plastic and reconstructive surgery, 2004, Volume: 114, Issue:6

    Topics: Adult; Astrocytoma; Baclofen; Cerebral Ventricle Neoplasms; Drug Resistance; Humans; Infusion Pumps,

2004
An unexpected recovery from permanent vegetative state.
    Brain injury, 2007, Volume: 21, Issue:1

    Topics: Adult; Baclofen; Consciousness; Follow-Up Studies; Humans; Male; Muscle Relaxants, Central; Muscle S

2007