Page last updated: 2024-10-23

baclofen and Lower Extremity Weakness, Spastic

baclofen has been researched along with Lower Extremity Weakness, Spastic in 11 studies

Research Excerpts

ExcerptRelevanceReference
"To assess the effects of intrathecal baclofen (ITB) therapy for the treatment of poststroke spastic hemiparesis on quality of life, functional independence, and upper, lower extremity (UE, LE) motor functions."7.77Prospective 12-month study of intrathecal baclofen therapy for poststroke spastic upper and lower extremity motor control and functional improvement. ( Acosta, F; Fisher, S; Lucke, J; Oh, IJ; Schiess, MC; Simpson, RK; Stimming, EF, 2011)
"To assess the effects of intrathecal baclofen (ITB) therapy for the treatment of poststroke spastic hemiparesis on quality of life, functional independence, and upper, lower extremity (UE, LE) motor functions."3.77Prospective 12-month study of intrathecal baclofen therapy for poststroke spastic upper and lower extremity motor control and functional improvement. ( Acosta, F; Fisher, S; Lucke, J; Oh, IJ; Schiess, MC; Simpson, RK; Stimming, EF, 2011)
"A 52-year-old woman with bilateral leg spasticity because of spinal multiple sclerosis underwent baclofen pump implantation, which was subcutaneously placed in the right upper quadrant."3.75Tangled catheter as a rare cause of baclofen pump malfunction. ( Fukuhara, T; Kuyama, H; Namba, Y; Tanaka, T, 2009)
"Fourteen patients with severe spastic paraparesis underwent serial evaluation of MAS in upper and lower limbs and serial testing of H reflex in soleus and flexor carpi radialis muscles, T wave in quadriceps and biceps brachii muscles, and blink reflex (BR) with and without prepulse, at baseline, and 15, 30, 60, 90, 120, and 180 min following ITB bolus application."2.76Neurophysiological evidence for muscle tone reduction by intrathecal baclofen at the brainstem level. ( Kofler, M; Kumru, H; Schindler, C; Stetkarova, I; Vidal, J, 2011)
"Hereditary Spastic Paraparesis (HSP) causes lower limb spasticity, pain and limits ambulation resulting in a negative impact on an individual's quality of life."1.72The use of intrathecal baclofen for management of spasticity in hereditary spastic paraparesis: A case series. ( Goodden, J; Lodh, R; Mulkeen, A; Peacock, S; Pointon, R; Raza, R; Whelan, H; Wilsmore, C, 2022)
"A neurological examination revealed spastic paraparesis with pathological reflexes on all four extremities."1.62Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy. ( Inaba, A; Inaji, M; Nishida, Y; Orimo, S; Sato, N; Shinya, A; Takahashi, M; Yokota, T, 2021)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Pointon, R1
Whelan, H1
Raza, R1
Peacock, S1
Wilsmore, C1
Mulkeen, A1
Goodden, J1
Lodh, R1
Shinya, A1
Takahashi, M1
Sato, N1
Nishida, Y1
Inaba, A1
Inaji, M1
Yokota, T1
Orimo, S1
Pancucci, G1
Perez-Prat, G1
Rivero-GarvĂ­a, M1
Mayorga-Buiza, MJ1
Marquez-Rivas, J1
Nakajima, T1
Akagawa, H1
Ochiai, T1
Hayashi, M1
Goto, S1
Taira, T1
Okada, Y1
Kumru, H1
Stetkarova, I1
Schindler, C1
Vidal, J1
Kofler, M1
Schiess, MC1
Oh, IJ1
Stimming, EF1
Lucke, J1
Acosta, F1
Fisher, S1
Simpson, RK1
Molteni, F1
Carda, S1
Cazzaniga, M1
Magoni, L1
Rossini, M1
Caimmi, M1
Kolaski, K1
Lambrecq, V1
Muller, F1
Joseph, PA1
Cuny, E1
Mazaux, JM1
Barat, M1
Fukuhara, T1
Tanaka, T1
Namba, Y1
Kuyama, H1
Dan, B1
Bouillot, E1
Bengoetxea, A1
Cheron, G1

Trials

1 trial available for baclofen and Lower Extremity Weakness, Spastic

ArticleYear
Neurophysiological evidence for muscle tone reduction by intrathecal baclofen at the brainstem level.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2011, Volume: 122, Issue:6

    Topics: Adolescent; Adult; Baclofen; Brain Stem; Dose-Response Relationship, Drug; Electric Stimulation; Ele

2011

Other Studies

10 other studies available for baclofen and Lower Extremity Weakness, Spastic

ArticleYear
The use of intrathecal baclofen for management of spasticity in hereditary spastic paraparesis: A case series.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2022, Volume: 36

    Topics: Adolescent; Baclofen; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Relaxan

2022
Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy.
    Internal medicine (Tokyo, Japan), 2021, Jul-15, Volume: 60, Issue:14

    Topics: Abnormalities, Multiple; Adult; Baclofen; Connexin 43; Craniofacial Abnormalities; Eye Abnormalities

2021
Subfascial expansive plasty for intrathecal baclofen pump replacement. A technical note.
    The journal of spinal cord medicine, 2016, Volume: 39, Issue:1

    Topics: Baclofen; Equipment Failure; Fasciotomy; Humans; Infusion Pumps, Implantable; Male; Neurosurgical Pr

2016
[Intrathecal baclofen therapy for spastic paraparesis due to aortic dissecting aneurysm; recent progress in treatment strategy].
    Kyobu geka. The Japanese journal of thoracic surgery, 2009, Volume: 62, Issue:12

    Topics: Aortic Aneurysm, Thoracic; Aortic Dissection; Baclofen; Humans; Injections, Spinal; Male; Middle Age

2009
Prospective 12-month study of intrathecal baclofen therapy for poststroke spastic upper and lower extremity motor control and functional improvement.
    Neuromodulation : journal of the International Neuromodulation Society, 2011, Volume: 14, Issue:1

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Female; Humans; Injections, Spinal; Lower Extremi

2011
Instrumental evaluation of gait modifications before and during intrathecal baclofen therapy: a 2-year follow-up case study.
    American journal of physical medicine & rehabilitation, 2005, Volume: 84, Issue:4

    Topics: Adult; Baclofen; Follow-Up Studies; Gait Disorders, Neurologic; Humans; Injections, Spinal; Male; Mu

2005
Use of intrathecal baclofen in a child with spastic paraparesis related to human immunodeficiency virus infection: A case report.
    Archives of physical medicine and rehabilitation, 2006, Volume: 87, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Baclofen; Child; Female; Humans; Injections, Spinal; Muscle Rela

2006
[Intrathecal baclofen in hereditary spastic paraparesis: benefits and limitations].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2007, Volume: 50, Issue:7

    Topics: Baclofen; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male;

2007
Tangled catheter as a rare cause of baclofen pump malfunction.
    Surgical neurology, 2009, Volume: 72, Issue:1

    Topics: Baclofen; Catheters, Indwelling; Female; Humans; Infusion Pumps, Implantable; Middle Aged; Multiple

2009
Effect of intrathecal baclofen on gait control in human hereditary spastic paraparesis.
    Neuroscience letters, 2000, Feb-25, Volume: 280, Issue:3

    Topics: Adult; Baclofen; Biomechanical Phenomena; Gait; Humans; Injections, Spinal; Locomotion; Muscle Relax

2000