baclofen has been researched along with Liver Diseases, Alcoholic in 8 studies
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data from a randomised controlled trial (RCT) (N = 104), in which AUD patients received placebo or baclofen (30 mg/day or 75 mg/day) for 12 weeks, were analysed to determine predictive effects of the following four clinical characteristics: alcoholic liver disease (ALD), baseline alcohol consumption, craving and anxiety." | 5.30 | Clinical Predictors of Response to Baclofen in the Treatment of Alcohol use Disorder: Results from the BacALD Trial. ( Baillie, A; Haber, PS; Morley, KC; Rombouts, SA, 2019) |
| "Effective treatments for alcohol use disorders in those with significant liver disease are critically lacking." | 2.78 | The efficacy and biobehavioural basis of baclofen in the treatment of alcoholic liver disease (BacALD): study protocol for a randomised controlled trial. ( Baillie, A; Haber, PS; Leung, S; Morley, KC, 2013) |
| " Further randomized studies alongside investigation of dosing strategies are required." | 1.46 | A prospective cohort study examining the effectiveness of baclofen in the maintenance of abstinence in alcohol use disorder patients attending a joint liver and alcohol treatment clinic. ( Gilmore, I; Owens, L; Pirmohamed, M; Richardson, P; Rose, A; Thompson, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Owens, L | 1 |
| Thompson, A | 1 |
| Rose, A | 1 |
| Gilmore, I | 1 |
| Pirmohamed, M | 1 |
| Richardson, P | 1 |
| Morley, KC | 5 |
| Baillie, A | 4 |
| Fraser, I | 1 |
| Furneaux-Bate, A | 1 |
| Dore, G | 1 |
| Roberts, M | 1 |
| Abdalla, A | 1 |
| Phung, N | 1 |
| Haber, PS | 5 |
| Lagopoulos, J | 1 |
| Logge, W | 1 |
| Adams, C | 1 |
| Logge, WB | 1 |
| Baillie, AJ | 1 |
| Braillon, A | 1 |
| Naudet, F | 1 |
| Rombouts, SA | 1 |
| Leung, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exploring the Efficacy and Biobehavioural Basis of Baclofen in the Treatment of Alcoholic Liver Disease[NCT01711125] | Phase 3 | 104 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for baclofen and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial.
Topics: Adult; Alcoholism; Baclofen; Double-Blind Method; Female; GABA-B Receptor Agonists; Humans; Liver Di | 2018 |
Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study.
Topics: Baclofen; Brain; Double-Blind Method; Female; GABA-B Receptor Agonists; Humans; Liver Diseases, Alco | 2020 |
Executive Functioning Moderates Responses to Appetitive Cues: A Study in Severe Alcohol Use Disorder and Alcoholic Liver Disease.
Topics: Adult; Aged; Alcoholism; Baclofen; Cues; Double-Blind Method; Executive Function; Female; GABA-B Rec | 2019 |
Clinical Predictors of Response to Baclofen in the Treatment of Alcohol use Disorder: Results from the BacALD Trial.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Alcoholism; Anxiety; Baclofen; Craving; Dose-Response Rel | 2019 |
The efficacy and biobehavioural basis of baclofen in the treatment of alcoholic liver disease (BacALD): study protocol for a randomised controlled trial.
Topics: Alcohol Drinking; Alcoholism; Baclofen; Clinical Protocols; Double-Blind Method; Drug Administration | 2013 |
3 other studies available for baclofen and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
A prospective cohort study examining the effectiveness of baclofen in the maintenance of abstinence in alcohol use disorder patients attending a joint liver and alcohol treatment clinic.
Topics: Adult; Aged; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Baclofen; Bilirubin; Biomarkers; Coho | 2017 |
Letter to the Editor: No Baclofen for Alcohol Use Disorders Even More When Liver Disease Is Serious!
Topics: Alcoholism; Baclofen; End Stage Liver Disease; Humans; Liver Diseases, Alcoholic | 2019 |
KASL clinical practice guidelines: management of alcoholic liver disease.
Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol-Related Disorders; Baclofen; Disulfiram; Fatty Liver, | 2013 |