baclofen has been researched along with Intellectual Disability in 10 studies
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "There are few reports of spasticity treatment for people with ID, and none of functionally meaningful outcomes." | 1.36 | Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability. ( Ayers, GD; Blair, CR; Charles, PD; Gill, CE; Konrad, PE; Putman, MS; Roberts, AG; Taylor, HM, 2010) |
| "During an outcomes study of spasticity treatment at a developmental center for 62 residents with profound intellectual disabilities, either botulinum toxin A (BTX-A), intrathecal baclofen (ITB), or both were recommended with physical and occupational therapy." | 1.36 | Discordance in informed consent response on the basis of demographic factors: brief report. ( Charles, PD; Gill, CE; Harrison, CH; Nunez-Wallace, KR; Taylor, HM, 2010) |
| "To ascertain the prevalence of spasticity among adults living in a developmental center and to document the development of spasticity treatment plans for this population." | 1.32 | Spasticity in adults living in a developmental center. ( Charles, PD; Damian, MM; Noel-Spaudling, S; Pfister, AA; Roberts, AG; Taylor, HM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoppel, LJ | 1 |
| Kazdoba, TM | 1 |
| Schaffler, MD | 1 |
| Preza, AR | 1 |
| Heynen, A | 1 |
| Crawley, JN | 1 |
| Bear, MF | 1 |
| Marvulli, R | 1 |
| Chiumarulo, P | 1 |
| Nisi, M | 1 |
| Barulli, L | 1 |
| Megna, G | 1 |
| Pietro, F | 1 |
| Ianieri, G | 1 |
| Megna, M | 1 |
| Charles, PD | 3 |
| Gill, CE | 2 |
| Taylor, HM | 3 |
| Putman, MS | 1 |
| Blair, CR | 1 |
| Roberts, AG | 2 |
| Ayers, GD | 1 |
| Konrad, PE | 1 |
| Nunez-Wallace, KR | 1 |
| Harrison, CH | 1 |
| Gandal, MJ | 1 |
| Sisti, J | 1 |
| Klook, K | 1 |
| Ortinski, PI | 1 |
| Leitman, V | 1 |
| Liang, Y | 1 |
| Thieu, T | 1 |
| Anderson, R | 1 |
| Pierce, RC | 1 |
| Jonak, G | 1 |
| Gur, RE | 1 |
| Carlson, G | 1 |
| Siegel, SJ | 1 |
| Pfister, AA | 1 |
| Noel-Spaudling, S | 1 |
| Damian, MM | 1 |
| Pirovino, M | 1 |
| Meier, J | 1 |
| Meyer, M | 1 |
| Waldmeier, P | 1 |
| Schmid, M | 1 |
| Primrose, DA | 1 |
| Yassa, R | 1 |
| Nair, V | 1 |
| Dimitry, R | 1 |
| Yamaguchi, S | 1 |
| Orii, T | 1 |
| Yasuda, K | 1 |
| Kohno, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inter-Rater Reliability of a Spasticity Diagnosis Algorithm[NCT01644123] | 72 participants (Actual) | Observational | 2013-04-30 | Completed | |||
| Using Telemedicine to Improve Spasticity Diagnosis Rates[NCT03211390] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility[NCT03250988] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity[NCT03209960] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for baclofen and Intellectual Disability
| Article | Year |
|---|---|
Treatment of self-injurious behaviour with a GABA (gamma-aminobutyric acid) analogue.
Topics: Adolescent; Adult; Anorexia; Baclofen; Child; Clinical Trials as Topic; Double-Blind Method; Epileps | 1979 |
9 other studies available for baclofen and Intellectual Disability
| Article | Year |
|---|---|
R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.
Topics: Animals; Autistic Disorder; Baclofen; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, | 2018 |
Use Of External Intrathecal Infusion Pumps In The Management Of Septic Complications: A Case Report.
Topics: Abdomen; Administration, Oral; Adolescent; Anti-Bacterial Agents; Baclofen; Catheter-Related Infecti | 2015 |
Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2010 |
Discordance in informed consent response on the basis of demographic factors: brief report.
Topics: Baclofen; Black or African American; Botulinum Toxins, Type A; Caregivers; Female; Humans; Informed | 2010 |
GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.
Topics: Animals; Autistic Disorder; Baclofen; Disease Models, Animal; Evoked Potentials, Auditory; Explorato | 2012 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
[Malignant neuroleptics syndrome].
Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal | 1984 |
Prevalence of tardive dystonia.
Topics: Adult; Aged; Antipsychotic Agents; Baclofen; Cross-Sectional Studies; Dementia; Drug Therapy, Combin | 1986 |
A case of glutaric aciduria type I with unique abnormalities in the cerebral CT findings.
Topics: Baclofen; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutarates; Glutary | 1987 |