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baclofen and Hypoxia

baclofen has been researched along with Hypoxia in 10 studies

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"Baclofen, the agonist of GABA(B) receptors, influences hypoxia-induced deficits in learning and memory processes."7.78Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia. ( Car, H; Michaluk, P, 2012)
"We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia."7.71Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001)
"Baclofen, the agonist of GABA(B) receptors, influences hypoxia-induced deficits in learning and memory processes."3.78Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia. ( Car, H; Michaluk, P, 2012)
" Minute ventilation (Ve), tidal volume (Vt), and breathing frequency (f) during room air breathing and in response to 10 min of hypercapnia (8% CO(2)) and 30 min of hypoxia (10% O(2)) were measured by the barometric method, and peak oxygen consumption (Vo(2 peak)) was measured by an enclosed metabolic treadmill following the randomized blinded subcutaneous administration of equal volumes of DMSO (vehicle), bicuculline (selective GABA(A) receptor antagonist, 1 mg/kg), and phaclofen (selective GABA(B) receptor antagonist, 1 mg/kg)."3.74GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats. ( Chen, JS; Huang, CY; Lee, SD; Lo, MJ; Ting, H; Yang, AL, 2007)
"We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia."3.71Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001)
" Cetyl GABA, sodium and lithium hydroxybutyrates and phenibut were shown to be able to decrease the retrograde amnesia caused by electroshock in passive avoidance performance."3.67[Nootropic properties of gamma-aminobutyric acid derivatives]. ( Ostrovskaia, RU; Trofimov, SS, 1984)
"A case of post-anoxic action myoclonus is reported in which a very good control of the myoclonic jerks was achieved with levodopa, gaba and bacoflen, while the antiepileptic drugs did not seem to be useful."3.66Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs. ( Coletti, A; Mandelli, A; Minoli, G; Tredici, G, 1980)
"We studied the effects of GABA on anoxia-induced injury in CNS white matter using optic nerves exposed to 60 min of anoxia."1.29Endogenous GABA attenuates CNS white matter dysfunction following anoxia. ( Fern, R; Ransom, BR; Waxman, SG, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birthi, P1
Walters, C1
Ortiz Vargas, O1
Karandikar, N1
Car, H2
Michaluk, P1
Francisco, GE1
Hu, MM1
Boake, C1
Ivanhoe, CB1
Yang, AL1
Lo, MJ1
Ting, H1
Chen, JS1
Huang, CY1
Lee, SD1
Brust, TB1
Cayabyab, FS1
MacVicar, BA1
Coletti, A1
Mandelli, A1
Minoli, G1
Tredici, G1
Ostrovskaia, RU1
Trofimov, SS1
Fern, R1
Waxman, SG1
Ransom, BR1
Oksztel, R1
Nadlewska, A1
Wiśniewski, K1
Tabata, M1
Kurosawa, H1
Kikuchi, Y1
Hida, W1
Ogawa, H1
Okabe, S1
Tun, Y1
Hattori, T1
Shirato, K1

Other Studies

10 other studies available for baclofen and Hypoxia

ArticleYear
The use of intrathecal baclofen therapy for myoclonus in a patient with Lance Adams syndrome.
    PM & R : the journal of injury, function, and rehabilitation, 2011, Volume: 3, Issue:7

    Topics: Accidents, Traffic; Adult; Baclofen; Humans; Hypoxia; Injections, Spinal; Male; Muscle Relaxants, Ce

2011
Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:3

    Topics: Animals; Avoidance Learning; Baclofen; Female; GABA-B Receptor Agonists; Hippocampus; Hypoxia; Matri

2012
Efficacy of early use of intrathecal baclofen therapy for treating spastic hypertonia due to acquired brain injury.
    Brain injury, 2005, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Baclofen; Brain Injuries; Child; Disability Evaluation; Drug Delivery Syste

2005
GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:1

    Topics: Animals; Baclofen; Bicuculline; Dimethyl Sulfoxide; GABA Antagonists; Hypercapnia; Hypoxia; Male; Ob

2007
C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus.
    Neuropharmacology, 2007, Volume: 53, Issue:8

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newb

2007
Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs.
    Journal of neurology, 1980, Volume: 223, Issue:1

    Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hypox

1980
[Nootropic properties of gamma-aminobutyric acid derivatives].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 97, Issue:2

    Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classi

1984
Endogenous GABA attenuates CNS white matter dysfunction following anoxia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:1 Pt 2

    Topics: Animals; Axons; Baclofen; Central Nervous System Diseases; Enzyme Activation; Female; gamma-Aminobut

1995
Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats.
    Pharmacological research, 2001, Volume: 44, Issue:4

    Topics: Amnesia; Animals; Anxiety; Avoidance Learning; Baclofen; Disease Models, Animal; Exploratory Behavio

2001
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; M

2001
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