Page last updated: 2024-10-23
baclofen and Hypoxia
baclofen has been researched along with Hypoxia in 10 studies
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Baclofen, the agonist of GABA(B) receptors, influences hypoxia-induced deficits in learning and memory processes." | 7.78 | Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia. ( Car, H; Michaluk, P, 2012) |
| "We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia." | 7.71 | Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001) |
| "Baclofen, the agonist of GABA(B) receptors, influences hypoxia-induced deficits in learning and memory processes." | 3.78 | Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia. ( Car, H; Michaluk, P, 2012) |
| " Minute ventilation (Ve), tidal volume (Vt), and breathing frequency (f) during room air breathing and in response to 10 min of hypercapnia (8% CO(2)) and 30 min of hypoxia (10% O(2)) were measured by the barometric method, and peak oxygen consumption (Vo(2 peak)) was measured by an enclosed metabolic treadmill following the randomized blinded subcutaneous administration of equal volumes of DMSO (vehicle), bicuculline (selective GABA(A) receptor antagonist, 1 mg/kg), and phaclofen (selective GABA(B) receptor antagonist, 1 mg/kg)." | 3.74 | GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats. ( Chen, JS; Huang, CY; Lee, SD; Lo, MJ; Ting, H; Yang, AL, 2007) |
| "We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia." | 3.71 | Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001) |
| " Cetyl GABA, sodium and lithium hydroxybutyrates and phenibut were shown to be able to decrease the retrograde amnesia caused by electroshock in passive avoidance performance." | 3.67 | [Nootropic properties of gamma-aminobutyric acid derivatives]. ( Ostrovskaia, RU; Trofimov, SS, 1984) |
| "A case of post-anoxic action myoclonus is reported in which a very good control of the myoclonic jerks was achieved with levodopa, gaba and bacoflen, while the antiepileptic drugs did not seem to be useful." | 3.66 | Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs. ( Coletti, A; Mandelli, A; Minoli, G; Tredici, G, 1980) |
| "We studied the effects of GABA on anoxia-induced injury in CNS white matter using optic nerves exposed to 60 min of anoxia." | 1.29 | Endogenous GABA attenuates CNS white matter dysfunction following anoxia. ( Fern, R; Ransom, BR; Waxman, SG, 1995) |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Birthi, P | 1 |
| Walters, C | 1 |
| Ortiz Vargas, O | 1 |
| Karandikar, N | 1 |
| Car, H | 2 |
| Michaluk, P | 1 |
| Francisco, GE | 1 |
| Hu, MM | 1 |
| Boake, C | 1 |
| Ivanhoe, CB | 1 |
| Yang, AL | 1 |
| Lo, MJ | 1 |
| Ting, H | 1 |
| Chen, JS | 1 |
| Huang, CY | 1 |
| Lee, SD | 1 |
| Brust, TB | 1 |
| Cayabyab, FS | 1 |
| MacVicar, BA | 1 |
| Coletti, A | 1 |
| Mandelli, A | 1 |
| Minoli, G | 1 |
| Tredici, G | 1 |
| Ostrovskaia, RU | 1 |
| Trofimov, SS | 1 |
| Fern, R | 1 |
| Waxman, SG | 1 |
| Ransom, BR | 1 |
| Oksztel, R | 1 |
| Nadlewska, A | 1 |
| Wiśniewski, K | 1 |
| Tabata, M | 1 |
| Kurosawa, H | 1 |
| Kikuchi, Y | 1 |
| Hida, W | 1 |
| Ogawa, H | 1 |
| Okabe, S | 1 |
| Tun, Y | 1 |
| Hattori, T | 1 |
| Shirato, K | 1 |
Other Studies
10 other studies available for baclofen and Hypoxia
| Article | Year |
|---|---|
The use of intrathecal baclofen therapy for myoclonus in a patient with Lance Adams syndrome.
Topics: Accidents, Traffic; Adult; Baclofen; Humans; Hypoxia; Injections, Spinal; Male; Muscle Relaxants, Ce | 2011 |
Baclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia.
Topics: Animals; Avoidance Learning; Baclofen; Female; GABA-B Receptor Agonists; Hippocampus; Hypoxia; Matri | 2012 |
Efficacy of early use of intrathecal baclofen therapy for treating spastic hypertonia due to acquired brain injury.
Topics: Adolescent; Adult; Aged; Baclofen; Brain Injuries; Child; Disability Evaluation; Drug Delivery Syste | 2005 |
GABA(A) and GABA(B) receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats.
Topics: Animals; Baclofen; Bicuculline; Dimethyl Sulfoxide; GABA Antagonists; Hypercapnia; Hypoxia; Male; Ob | 2007 |
C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newb | 2007 |
Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs.
Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hypox | 1980 |
[Nootropic properties of gamma-aminobutyric acid derivatives].
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classi | 1984 |
Endogenous GABA attenuates CNS white matter dysfunction following anoxia.
Topics: Animals; Axons; Baclofen; Central Nervous System Diseases; Enzyme Activation; Female; gamma-Aminobut | 1995 |
Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats.
Topics: Amnesia; Animals; Anxiety; Avoidance Learning; Baclofen; Disease Models, Animal; Exploratory Behavio | 2001 |
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; M | 2001 |