baclofen has been researched along with Hypotension in 10 studies
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 microg/rat) in awake male Holtzman rats." | 3.73 | The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats. ( Callera, JC; Colombari, E; De Luca, LA; Menani, JV, 2005) |
| "Baclofen is a centrally acting skeletal muscle relaxant approved by the US Food and Drug Administration (FDA) for the treatment of muscle spasticity, but the immediate release mode of administration and rapid absorption has been associated with adverse effects." | 1.56 | Design, characterization and in vivo evaluation of modified release baclofen floating coated beads. ( Abdelkader, H; Ibrahim, M; Naguib, YW; Sarhan, HA, 2020) |
| "Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system." | 1.33 | Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005) |
| "There was no correlation between the dosage of baclofen and the clinical outcome." | 1.32 | [Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibrahim, M | 1 |
| Sarhan, HA | 1 |
| Naguib, YW | 1 |
| Abdelkader, H | 1 |
| Chodorowski, Z | 2 |
| Sein Anand, J | 2 |
| Wiśniewski, M | 1 |
| Lew, SM | 1 |
| Psaty, EL | 1 |
| Abbott, R | 1 |
| Callera, JC | 1 |
| Colombari, E | 1 |
| De Luca, LA | 1 |
| Menani, JV | 1 |
| Burda, P | 1 |
| Grande, LA | 1 |
| Loeser, JD | 1 |
| Samii, A | 1 |
| Brodkey, JA | 1 |
| Feler, CA | 1 |
| Green, LB | 1 |
| Nelson, VS | 1 |
| Sill, JC | 1 |
| Schumacher, K | 1 |
| Southorn, PA | 1 |
| Reuter, J | 1 |
| Yaksh, TL | 1 |
| Cohen, MB | 1 |
| Gailey, RA | 1 |
| McCoy, GC | 1 |
1 review available for baclofen and Hypotension
| Article | Year |
|---|---|
Death after acute withdrawal of intrathecal baclofen: case report and literature review.
Topics: Administration, Oral; Adult; Baclofen; Brain Death; Cervical Vertebrae; Equipment Failure; Fatal Out | 1999 |
1 trial available for baclofen and Hypotension
| Article | Year |
|---|---|
Bradycardia and hypotension associated with baclofen used during general anesthesia.
Topics: Adult; Aged; Anesthesia, General; Baclofen; Bradycardia; Clinical Trials as Topic; Double-Blind Meth | 1986 |
8 other studies available for baclofen and Hypotension
| Article | Year |
|---|---|
Design, characterization and in vivo evaluation of modified release baclofen floating coated beads.
Topics: Acrylic Resins; Administration, Oral; Animals; Baclofen; Biological Availability; Blood Pressure; De | 2020 |
[Acute intoxication with baclofen].
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist | 2004 |
An unusual cause of overdose after baclofen pump implantation: case report.
Topics: Adolescent; Baclofen; Cerebral Palsy; Consciousness Disorders; Contrast Media; Drug Overdose; Dyston | 2005 |
The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats.
Topics: Animals; Baclofen; Blood Pressure; Bradycardia; GABA Agonists; Heart Rate; Hypotension; Male; Muscim | 2005 |
Selected clinical aspects of acute intoxication with baclofen.
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal | 2005 |
Recurrent transient global amnesia with intrathecal baclofen.
Topics: Amnesia, Anterograde; Baclofen; Female; Humans; Hypotension; Injections, Spinal; Isosorbide Dinitrat | 2008 |
Hypotension following a trial intrathecal dose of baclofen.
Topics: Adult; Baclofen; Humans; Hypotension; Injections, Spinal; Male; Morphine; Spasm | 1993 |
Atropine in the treatment of baclofen overdose.
Topics: Adolescent; Atropine; Baclofen; Bradycardia; Humans; Hypotension; Male | 1986 |