Page last updated: 2024-10-23

baclofen and Hemiplegia

baclofen has been researched along with Hemiplegia in 17 studies

Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.

Research Excerpts

ExcerptRelevanceReference
"To explore whether intrathecal baclofen (ITB) therapy improves ambulation in stroke survivors."9.10Improvement in walking speed in poststroke spastic hemiplegia after intrathecal baclofen therapy: a preliminary study. ( Boake, C; Francisco, GE, 2003)
"To determine whether intrathecal administration of baclofen reduced spastic hypertonia in a hemiplegic patient after hemorrhagic stroke."7.74[Efficacy of intrathecal baclofen in the treatment of spasticity in stroke]. ( Cantalloube, S; Lamotte, D, 2007)
"To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia."7.72Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003)
"Intrathecal baclofen infusion (IBI) is an effective treatment for spasticity secondary to cerebral palsy (CP)."7.70Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy. ( Albright, AL; Gerszten, PC; Johnstone, GF, 1998)
"To explore whether intrathecal baclofen (ITB) therapy improves ambulation in stroke survivors."5.10Improvement in walking speed in poststroke spastic hemiplegia after intrathecal baclofen therapy: a preliminary study. ( Boake, C; Francisco, GE, 2003)
"To determine whether intrathecal administration of baclofen reduced spastic hypertonia in a hemiplegic patient after hemorrhagic stroke."3.74[Efficacy of intrathecal baclofen in the treatment of spasticity in stroke]. ( Cantalloube, S; Lamotte, D, 2007)
"To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia."3.72Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003)
"Intrathecal baclofen infusion (IBI) is an effective treatment for spasticity secondary to cerebral palsy (CP)."3.70Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy. ( Albright, AL; Gerszten, PC; Johnstone, GF, 1998)
"In a group of 17 patients with spastic hemiparesis, with a different etiology, 2 groups were separated."2.73[Assessment of spasticity therapy with baclofen pump in children]. ( Swierczyńska, A, 2007)
"When excessive spasticity is not sufficiently controlled by physical therapy and pharmacological treatment, patients can have recourse to neurosurgery: neurostimulation, intrathecal baclofen or selective ablative procedures."2.41Neurosurgery for spasticity. ( Mertens, P; Sindou, MP, 2000)
"There are few reports of spasticity treatment for people with ID, and none of functionally meaningful outcomes."1.36Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability. ( Ayers, GD; Blair, CR; Charles, PD; Gill, CE; Konrad, PE; Putman, MS; Roberts, AG; Taylor, HM, 2010)
"Treatment of spasticity with intrathecal baclofen pump implantation is a chance for clinical improvement in patients with severe spasticity."1.34[The parents expectations after baclofen pump implantation in child with severe spasticity in physical rehabilitation and psychological aspects]. ( Fafara, A; Grzegorzewski, P; Kawecka, J; Kawecki, Z; Kwiatkowski, S, 2007)
"To ascertain the prevalence of spasticity among adults living in a developmental center and to document the development of spasticity treatment plans for this population."1.32Spasticity in adults living in a developmental center. ( Charles, PD; Damian, MM; Noel-Spaudling, S; Pfister, AA; Roberts, AG; Taylor, HM, 2003)
"On the spastic side a reflex with prolonged latencies and durations, as well as with decreased amplitudes and thresholds of both reflex responses was found."1.28Flexor reflex for assessment of common interneurone activity in spasticity. ( Milanov, IG, 1992)
"Thirty patients with old post-stroke spastic hemiparesis took part in the investigation."1.28Mechanisms of baclofen action on spasticity. ( Milanov, IG, 1992)
"Twelve spastic patients received single oral doses of a new anti-spastic drug DS103-282 (Sandoz) 6 mg, baclofen 20 mg, and placebo on three separate days."1.26Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. ( Hassan, N; McLellan, DL, 1980)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's3 (17.65)18.2507
2000's8 (47.06)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cleophax, C1
Goncalves, A1
Chasport, C1
de Beaugrenier, E1
Labat, L1
Declèves, X1
Mégarbane, B1
Charles, PD2
Gill, CE1
Taylor, HM2
Putman, MS1
Blair, CR1
Roberts, AG2
Ayers, GD1
Konrad, PE1
Kästner, S1
Rémy-Néris, O1
Tiffreau, V1
Bouilland, S1
Bussel, B1
Francisco, GE1
Boake, C1
Pfister, AA1
Noel-Spaudling, S1
Damian, MM1
Cooper, JA1
Ridley, B1
Lamotte, D1
Cantalloube, S1
Swierczyńska, A1
Fafara, A1
Kwiatkowski, S1
Kawecka, J1
Grzegorzewski, P1
Kawecki, Z1
Kirchner, P1
Hassan, N1
McLellan, DL1
Gerszten, PC1
Albright, AL1
Johnstone, GF1
Sindou, MP1
Mertens, P1
Milanov, IG2
Nakamura, R1
Tsuji, I1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inter-Rater Reliability of a Spasticity Diagnosis Algorithm[NCT01644123]72 participants (Actual)Observational2013-04-30Completed
Using Telemedicine to Improve Spasticity Diagnosis Rates[NCT03211390]60 participants (Actual)Observational2018-01-30Completed
Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility[NCT03250988]60 participants (Actual)Observational2018-01-30Completed
Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity[NCT03209960]60 participants (Actual)Observational2018-01-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for baclofen and Hemiplegia

ArticleYear
Neurosurgery for spasticity.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:3-4

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Combined Modality Therapy; Gai

2000

Trials

2 trials available for baclofen and Hemiplegia

ArticleYear
Improvement in walking speed in poststroke spastic hemiplegia after intrathecal baclofen therapy: a preliminary study.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:8

    Topics: Adult; Aged; Baclofen; Female; Hemiplegia; Humans; Infusion Pumps, Implantable; Injections, Spinal;

2003
[Assessment of spasticity therapy with baclofen pump in children].
    Przeglad lekarski, 2007, Volume: 64 Suppl 2

    Topics: Adolescent; Adult; Baclofen; Child; Feasibility Studies; Follow-Up Studies; GABA Agonists; Hemiplegi

2007

Other Studies

14 other studies available for baclofen and Hemiplegia

ArticleYear
Usefulness of plasma drug monitoring in severe baclofen poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:9

    Topics: Adult; Baclofen; Biomarkers; Drug Monitoring; Female; Hemiplegia; Humans; Muscle Relaxants, Central;

2015
Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Mar-15, Volume: 25, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2010
[Intrathecal baclofen therapy in ambulatory patients with spastic hemiparesis following stroke. Short report of two cases].
    Der Nervenarzt, 2010, Volume: 81, Issue:8

    Topics: Ambulatory Care; Baclofen; Cerebral Infarction; Dose-Response Relationship, Drug; Drug Administratio

2010
Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Ankle; Baclofen; Biomechanical Phenomena; Body Weight; Brain Injuries; Cerebral Palsy; Electr

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Spasticity in adults living in a developmental center.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:12

    Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi

2003
Response of intrathecal baclofen resistance to dose reduction.
    Neurology, 2006, Oct-24, Volume: 67, Issue:8

    Topics: Adult; Analgesics; Anticonvulsants; Baclofen; Dose-Response Relationship, Drug; Drug Resistance; Dru

2006
[Efficacy of intrathecal baclofen in the treatment of spasticity in stroke].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2007, Volume: 50, Issue:3

    Topics: Baclofen; Hemiplegia; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; Mu

2007
[The parents expectations after baclofen pump implantation in child with severe spasticity in physical rehabilitation and psychological aspects].
    Przeglad lekarski, 2007, Volume: 64 Suppl 2

    Topics: Activities of Daily Living; Adult; Baclofen; Cerebral Palsy; Child; Female; Follow-Up Studies; Hemip

2007
[Tasks and problems of general medical care in certain groups of disorders. Patients with mixed (motor and sensory) paralyses--from a neurological viewpoint].
    Zeitschrift fur arztliche Fortbildung, 1982, Jun-01, Volume: 76, Issue:11

    Topics: Baclofen; Demyelinating Diseases; Diazepam; Electrogalvanism, Intraoral; Exercise Therapy; Hemiplegi

1982
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
    Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:12

    Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiple

1980
Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy.
    Journal of neurosurgery, 1998, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Contracture; Femur; Follow-Up

1998
Flexor reflex for assessment of common interneurone activity in spasticity.
    Electromyography and clinical neurophysiology, 1992, Volume: 32, Issue:12

    Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Diso

1992
Mechanisms of baclofen action on spasticity.
    Acta neurologica Scandinavica, 1992, Volume: 85, Issue:5

    Topics: Baclofen; Cerebrovascular Disorders; Electromyography; Equipment Design; Female; Hemiplegia; Humans;

1992
Effect of antispastic drugs on rapid force generation of spastic muscle.
    The Tohoku journal of experimental medicine, 1986, Volume: 150, Issue:4

    Topics: Adult; Aged; Baclofen; Dantrolene; Electromyography; Hemiplegia; Humans; Male; Middle Aged; Muscle C

1986