Page last updated: 2024-10-23

baclofen and Fatigue

baclofen has been researched along with Fatigue in 7 studies

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"The present study was designed to examine the effects of administration of a GABAergic agonist (Baclofen) on run-time to exhaustion in trained and untrained rats, and on some indicators of fatigue."7.69Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue. ( Abdelmalki, A; Bigard, AX; Bonneau, D; Guezennec, CY; Merino, D, 1997)
"It has been shown that arbaclofen placarbil (AP) inhibits reflux in gastroesophageal reflux disease (GERD) following single oral dosing."5.15Arbaclofen placarbil in GERD: a randomized, double-blind, placebo-controlled study. ( Bian, A; Huff, FJ; Jones, DS; Stamler, D; Vakil, NB, 2011)
"The present study was designed to examine the effects of administration of a GABAergic agonist (Baclofen) on run-time to exhaustion in trained and untrained rats, and on some indicators of fatigue."3.69Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue. ( Abdelmalki, A; Bigard, AX; Bonneau, D; Guezennec, CY; Merino, D, 1997)
"Baclofen has shown promise in treating substance use disorders and also reduced binge frequency in an open-label trial."2.77Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study. ( Boan, J; Corwin, RL; Peters, KF; Ulbrecht, JS, 2012)
"Of all drug use to treat MS symptoms, treatment for pain accounts for nearly 30 % of total use."2.49Pain and multiple sclerosis: pathophysiology and treatment. ( Messmer Uccelli, M; Solaro, C; Trabucco, E, 2013)
"Multiple sclerosis is a demyelinating disorder of the central nervous system characterized by exacerbations and remissions of symptoms."2.38Update on multiple sclerosis therapy. ( Mitchell, G, 1993)
"Baclofen is the treatment of choice for spasticity and is usually given in doses of 30 to 80 mg/day, although higher doses may be used."2.37Multiple sclerosis. Current concepts in management. ( Giesser, B, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vakil, NB1
Huff, FJ1
Bian, A1
Jones, DS1
Stamler, D1
Corwin, RL1
Boan, J1
Peters, KF1
Ulbrecht, JS1
Angeli, C1
Ochsner, J1
Harkema, S1
Solaro, C1
Trabucco, E1
Messmer Uccelli, M1
Mitchell, G1
Abdelmalki, A1
Merino, D1
Bonneau, D1
Bigard, AX1
Guezennec, CY1
Giesser, B1

Reviews

3 reviews available for baclofen and Fatigue

ArticleYear
Pain and multiple sclerosis: pathophysiology and treatment.
    Current neurology and neuroscience reports, 2013, Volume: 13, Issue:1

    Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Baclofen; Cannabinoids; Fatigue; Humans;

2013
Update on multiple sclerosis therapy.
    The Medical clinics of North America, 1993, Volume: 77, Issue:1

    Topics: Amantadine; Baclofen; Fatigue; Humans; Immunosuppression Therapy; Interferons; Multiple Sclerosis; M

1993
Multiple sclerosis. Current concepts in management.
    Drugs, 1985, Volume: 29, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Baclofen; Dantrolene; Fatigue; Gastrointestina

1985

Trials

2 trials available for baclofen and Fatigue

ArticleYear
Arbaclofen placarbil in GERD: a randomized, double-blind, placebo-controlled study.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:8

    Topics: Adult; Aged; Baclofen; Dizziness; Double-Blind Method; Drug Administration Schedule; Fatigue; Female

2011
Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study.
    Behavioural pharmacology, 2012, Volume: 23, Issue:5-6

    Topics: Adult; Anxiety; Baclofen; Binge-Eating Disorder; Cross-Over Studies; Depression; Double-Blind Method

2012

Other Studies

2 other studies available for baclofen and Fatigue

ArticleYear
Effects of chronic baclofen use on active movement in an individual with a spinal cord injury.
    Spinal cord, 2012, Volume: 50, Issue:12

    Topics: Baclofen; Fatigue; Humans; Locomotion; Lower Extremity; Male; Motor Activity; Movement; Muscle Relax

2012
Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue.
    International journal of sports medicine, 1997, Volume: 18, Issue:2

    Topics: Analysis of Variance; Animals; Baclofen; Blood Glucose; Fatigue; GABA Agonists; Glycogen; Liver; Mal

1997