baclofen and Fatigue
baclofen has been researched along with Fatigue in 7 studies
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to examine the effects of administration of a GABAergic agonist (Baclofen) on run-time to exhaustion in trained and untrained rats, and on some indicators of fatigue." | 7.69 | Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue. ( Abdelmalki, A; Bigard, AX; Bonneau, D; Guezennec, CY; Merino, D, 1997) |
| "It has been shown that arbaclofen placarbil (AP) inhibits reflux in gastroesophageal reflux disease (GERD) following single oral dosing." | 5.15 | Arbaclofen placarbil in GERD: a randomized, double-blind, placebo-controlled study. ( Bian, A; Huff, FJ; Jones, DS; Stamler, D; Vakil, NB, 2011) |
| "The present study was designed to examine the effects of administration of a GABAergic agonist (Baclofen) on run-time to exhaustion in trained and untrained rats, and on some indicators of fatigue." | 3.69 | Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue. ( Abdelmalki, A; Bigard, AX; Bonneau, D; Guezennec, CY; Merino, D, 1997) |
| "Baclofen has shown promise in treating substance use disorders and also reduced binge frequency in an open-label trial." | 2.77 | Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study. ( Boan, J; Corwin, RL; Peters, KF; Ulbrecht, JS, 2012) |
| "Of all drug use to treat MS symptoms, treatment for pain accounts for nearly 30 % of total use." | 2.49 | Pain and multiple sclerosis: pathophysiology and treatment. ( Messmer Uccelli, M; Solaro, C; Trabucco, E, 2013) |
| "Multiple sclerosis is a demyelinating disorder of the central nervous system characterized by exacerbations and remissions of symptoms." | 2.38 | Update on multiple sclerosis therapy. ( Mitchell, G, 1993) |
| "Baclofen is the treatment of choice for spasticity and is usually given in doses of 30 to 80 mg/day, although higher doses may be used." | 2.37 | Multiple sclerosis. Current concepts in management. ( Giesser, B, 1985) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Vakil, NB | 1 |
| Huff, FJ | 1 |
| Bian, A | 1 |
| Jones, DS | 1 |
| Stamler, D | 1 |
| Corwin, RL | 1 |
| Boan, J | 1 |
| Peters, KF | 1 |
| Ulbrecht, JS | 1 |
| Angeli, C | 1 |
| Ochsner, J | 1 |
| Harkema, S | 1 |
| Solaro, C | 1 |
| Trabucco, E | 1 |
| Messmer Uccelli, M | 1 |
| Mitchell, G | 1 |
| Abdelmalki, A | 1 |
| Merino, D | 1 |
| Bonneau, D | 1 |
| Bigard, AX | 1 |
| Guezennec, CY | 1 |
| Giesser, B | 1 |
Reviews
3 reviews available for baclofen and Fatigue
| Article | Year |
|---|---|
Pain and multiple sclerosis: pathophysiology and treatment.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Baclofen; Cannabinoids; Fatigue; Humans; | 2013 |
Update on multiple sclerosis therapy.
Topics: Amantadine; Baclofen; Fatigue; Humans; Immunosuppression Therapy; Interferons; Multiple Sclerosis; M | 1993 |
Multiple sclerosis. Current concepts in management.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Baclofen; Dantrolene; Fatigue; Gastrointestina | 1985 |
Trials
2 trials available for baclofen and Fatigue
| Article | Year |
|---|---|
Arbaclofen placarbil in GERD: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aged; Baclofen; Dizziness; Double-Blind Method; Drug Administration Schedule; Fatigue; Female | 2011 |
Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study.
Topics: Adult; Anxiety; Baclofen; Binge-Eating Disorder; Cross-Over Studies; Depression; Double-Blind Method | 2012 |
Other Studies
2 other studies available for baclofen and Fatigue
| Article | Year |
|---|---|
Effects of chronic baclofen use on active movement in an individual with a spinal cord injury.
Topics: Baclofen; Fatigue; Humans; Locomotion; Lower Extremity; Male; Motor Activity; Movement; Muscle Relax | 2012 |
Administration of a GABAB agonist baclofen before running to exhaustion in the rat: effects on performance and on some indicators of fatigue.
Topics: Analysis of Variance; Animals; Baclofen; Blood Glucose; Fatigue; GABA Agonists; Glycogen; Liver; Mal | 1997 |