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baclofen and Epilepsy, Tonic-Clonic

baclofen has been researched along with Epilepsy, Tonic-Clonic in 6 studies

Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Research Excerpts

ExcerptRelevanceReference
"To determine whether seizures have age-specific features, we studied the role of gamma-aminobutyric acidB (GABAB) transmission in rats of various ages (9, 15, 30, and 60 postnatal days)."7.69Age-specific effects of baclofen on pentylenetetrazol-induced seizures in developing rats. ( Moshé, SL; Velísek, L; Velísková, J, 1996)
"To determine whether seizures have age-specific features, we studied the role of gamma-aminobutyric acidB (GABAB) transmission in rats of various ages (9, 15, 30, and 60 postnatal days)."3.69Age-specific effects of baclofen on pentylenetetrazol-induced seizures in developing rats. ( Moshé, SL; Velísek, L; Velísková, J, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wall, GC1
Wasiak, A1
Hicklin, GA1
Korkosz, A1
Zatorski, P1
Taracha, E1
Plaznik, A1
Kostowski, W1
Bienkowski, P1
Barker, I1
Grant, IS1
Lipscomb, DJ1
Meredith, TJ1
Terrence, CF1
Fromm, GH1
Velísková, J1
Velísek, L1
Moshé, SL1

Other Studies

6 other studies available for baclofen and Epilepsy, Tonic-Clonic

ArticleYear
An initially unsuspected case of baclofen overdose.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2006, Volume: 15, Issue:6

    Topics: Baclofen; Coma; Drug Overdose; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Muscle Relaxants,

2006
Ethanol blocks nicotine-induced seizures in mice: comparison with midazolam and baclofen.
    Alcohol (Fayetteville, N.Y.), 2006, Volume: 40, Issue:3

    Topics: Animals; Anticonvulsants; Baclofen; Central Nervous System Depressants; Disease Models, Animal; Dose

2006
Convulsions after abrupt withdrawal of baclofen.
    Lancet (London, England), 1982, Sep-04, Volume: 2, Issue:8297

    Topics: Baclofen; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged; Paraplegia; Substance Withdrawal Synd

1982
Baclofen overdose.
    Postgraduate medical journal, 1980, Volume: 56, Issue:652

    Topics: Baclofen; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged; Muscle Hypotonia; Respiratory Insuffi

1980
Complications of baclofen withdrawal.
    Archives of neurology, 1981, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Baclofen; Epilepsy, Tonic-Clonic; Female; Hallucinations; Humans; Male; Middle Ag

1981
Age-specific effects of baclofen on pentylenetetrazol-induced seizures in developing rats.
    Epilepsia, 1996, Volume: 37, Issue:8

    Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Epilepsy, Tonic-

1996