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baclofen and Dyskinesia, Drug-Induced

baclofen has been researched along with Dyskinesia, Drug-Induced in 35 studies

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
" I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride."7.68Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990)
" I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride."3.68Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990)
"One patient developed withdrawal symptoms after baclofen was stopped, and the other developed a manic attach while receiving the drug."2.37Baclofen-induced psychosis: two cases and a review. ( Iskandar, HL; Yassa, RY, 1988)
" The trouble occurs or is worsened when neuroleptics are withdrawn and is reduced when dosage is increased; it responds to the theoretical model of denervation supersensitivity."2.36[Tardive dyskinesia induced by neuroleptics. A review of the literature]. ( Cottereau, MJ; Deniker, P; Diepart, E, 1979)
"Baclofen and oxazepam were prescribed secondary to right-sided hemiparesis contractures."1.34Potential aripiprazole-mediated extrapyramidal symptoms in an adult with developmental disabilities. ( Brahm, NC; Brown, RC; McElwain, DL, 2007)
"Treatment with baclofen (4 mg/kg) did not modify spontaneous VCM."1.33Effects of baclofen on reserpine-induced vacuous chewing movements in mice. ( Abílio, VC; Castro, JP; Frussa-Filho, R; Fukushiro, DF; Medrano, WA; Ribeiro, Rde A; Silva, RH, 2006)
"When selegiline was stopped after 9 years of treatment, abnormal involuntary movements improved to pretreatment level and psychiatric behaviour returned to normal."1.32Adverse effects of dopamine potentiation by long-term treatment with selegiline. ( Hollán, S; Magyar, K; Vécsei, L, 2004)
"Baclofen was also useful in one monkey against a more dystonic form of dyskinesia."1.29Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys. ( Bédard, PJ; Gomez-Mancilla, B, 1993)
"Baclofen (Lioresal) is a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)."1.29Baclofen-induced dyskinesia. ( Blumenthal, FS; Ryan, DM, 1993)
"Tardive dystonia is an uncommon, disabling side effect of antipsychotic medication that is generally believed to be resistant to treatment."1.28Tardive dystonia: four case histories. ( Korn, ML; Simpson, GM; Yadalam, KG, 1990)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's5 (14.29)18.2507
2000's4 (11.43)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alabed, S1
Latifeh, Y1
Mohammad, HA1
Bergman, H1
Niehaus, MT1
Elliott, NC1
Katz, KD1
Hollán, S1
Vécsei, L1
Magyar, K1
Peixoto, MF1
Araujo, NP1
Silva, RH2
Castro, JP2
Fukushiro, DF2
Faria, RR1
Zanier-Gomes, PH1
Medrano, WA2
Frussa-Filho, R2
Abílio, VC2
Ribeiro, Rde A1
Brahm, NC1
McElwain, DL1
Brown, RC1
Liebman, J1
Neale, R1
Stewart, RM1
Rollins, J1
Beckham, B1
Roffman, M2
Tegeler, J1
Wöller, W1
Andrade, LA1
Bertolucci, PH1
Pereira, JS1
Marsden, CD1
Sheehy, MP1
Wolf, ME2
Keener, S1
Mathis, P1
Mosnaim, AD2
Nair, NP2
Lal, S1
Schwartz, G2
Thavundayil, JX1
Almy, G1
Toll, M1
Rastogi, SK1
Rastogi, RB1
Lapierre, YD1
Singhal, RL1
Häggström, JE1
Feder, R1
Moore, DC2
Gomez-Mancilla, B1
Bédard, PJ1
Ryan, DM1
Blumenthal, FS1
Dressler, D1
Yassa, R2
Ruiz-Navarro, J1
Diepart, E1
Cottereau, MJ1
Deniker, P1
Campanini, T1
Catalano, A1
De Risio, C1
Forino, V1
Simpson, GM2
Lee, JH1
Shrivastava, RK1
Branchey, MH1
Lees, AJ1
Shaw, KM1
Stern, GM1
Gerlach, J2
Rye, T1
Kristjansen, P1
Amsterdam, J1
Mendels, J1
Yadalam, KG1
Korn, ML1
Sandyk, R2
Nair, V1
Dimitry, R1
Yassa, RY1
Iskandar, HL1
Glazer, WM1
Bowers, MB1
Bunney, BS1

Reviews

4 reviews available for baclofen and Dyskinesia, Drug-Induced

ArticleYear
Gamma-aminobutyric acid agonists for antipsychotic-induced tardive dyskinesia.
    The Cochrane database of systematic reviews, 2018, 04-17, Volume: 4

    Topics: Antipsychotic Agents; Baclofen; Dyskinesia, Drug-Induced; GABA Agonists; gamma-Aminobutyric Acid; Hu

2018
[Tardive dyskinesia: I. Physiopathology and treatment].
    Arquivos de neuro-psiquiatria, 1984, Volume: 42, Issue:4

    Topics: Animals; Antipsychotic Agents; Baclofen; Binding Sites; Dopamine; Dyskinesia, Drug-Induced; Humans;

1984
[Tardive dyskinesia induced by neuroleptics. A review of the literature].
    L'Encephale, 1979, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Athetosis; Baclofen; Child; Chorea; Diag

1979
Baclofen-induced psychosis: two cases and a review.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:8

    Topics: Acute Disease; Adult; Aged; Baclofen; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Humans; Ma

1988

Trials

7 trials available for baclofen and Dyskinesia, Drug-Induced

ArticleYear
Baclofen in tardive dyskinesia patients maintained on neuroleptics.
    Clinical neuropharmacology, 1982, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Baclofen; Clinical Trials as Topic; Double-Blind Meth

1982
GABA and movement disorders.
    Advances in biochemical psychopharmacology, 1981, Volume: 30

    Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced;

1981
Baclofen in the treatment of tardive dyskinesia.
    The American journal of psychiatry, 1978, Volume: 135, Issue:12

    Topics: Adult; Aminobutyrates; Antipsychotic Agents; Baclofen; Clinical Trials as Topic; Double-Blind Method

1978
Baclofen in the treatment of tardive dyskinesia and schizophrenia.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:2

    Topics: Adult; Aminobutyrates; Baclofen; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Female; Humans;

1978
Baclofen in Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:8

    Topics: Aged; Aminobutyrates; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Indu

1978
Effect of baclofen on tardive dyskinesia.
    Psychopharmacology, 1978, Mar-01, Volume: 56, Issue:2

    Topics: Aged; Aminobutyrates; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Indu

1978
The treatment of tardive dyskinesia with baclofen.
    Psychopharmacology, 1985, Volume: 87, Issue:4

    Topics: Adolescent; Adult; Aged; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-I

1985

Other Studies

24 other studies available for baclofen and Dyskinesia, Drug-Induced

ArticleYear
Baclofen Toxicity Causing Acute, Reversible Dyskinesia.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:4

    Topics: Aged, 80 and over; Back Pain; Baclofen; Coronary Artery Disease; Diabetes Mellitus; Drug Interaction

2016
Adverse effects of dopamine potentiation by long-term treatment with selegiline.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anemia, Hemolytic, Congenital; Antiparkinson Agents; Baclofen; Basal Ganglia; Bas

2004
Effects of gabaergic drugs on reserpine-induced oral dyskinesia.
    Behavioural brain research, 2005, May-07, Volume: 160, Issue:1

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Diazepam; Dose-Resp

2005
Effects of baclofen on reserpine-induced vacuous chewing movements in mice.
    Brain research bulletin, 2006, Feb-15, Volume: 68, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Animals; Baclofen; Brain; Brain Chemistry; Dose-Response Relationship,

2006
Potential aripiprazole-mediated extrapyramidal symptoms in an adult with developmental disabilities.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Apr-15, Volume: 64, Issue:8

    Topics: Adult; Algorithms; Antipsychotic Agents; Aripiprazole; Baclofen; Basal Ganglia Diseases; Citalopram;

2007
Neuroleptic-induced acute dyskinesias in squirrel monkeys: correlation with propensity to cause extrapyramidal side effects.
    Psychopharmacology, 1980, Volume: 68, Issue:1

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Baclofen; Basal Ganglia Diseases; Clozapine; Diaz

1980
[Therapeutic measures in tardive dyskinesia].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:6

    Topics: Age Factors; Amantadine; Antipsychotic Agents; Baclofen; Benzodiazepines; Bromocriptine; Deanol; Dih

1983
Phenylethylamine-like properties of baclofen.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: Adult; Aged; Baclofen; Chronic Disease; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans;

1983
Effect of sodium valproate and baclofen in tardive dyskinesia: clinical and neuroendocrine studies.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Adult; Baclofen; Chronic Disease; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Halop

1980
Mania associated with the use of baclofen.
    Biological psychiatry, 1982, Volume: 17, Issue:6

    Topics: Adult; Affective Disorders, Psychotic; Baclofen; Bipolar Disorder; Dyskinesia, Drug-Induced; Humans;

1982
Effect of baclofen and haloperidol on gamma-aminobutyric acid and dopamine systems in an animal model of tardive dyskinesia.
    General pharmacology, 1982, Volume: 13, Issue:6

    Topics: Animals; Baclofen; Brain Chemistry; Disease Models, Animal; Dopamine; Drug Interactions; Dyskinesia,

1982
[Tardive dyskinesia caused by metoclopramide therapy].
    Lakartidningen, 1981, Jan-28, Volume: 78, Issue:5

    Topics: Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Metoclopramide

1981
Baclofen and tardive dyskinesia.
    The American journal of psychiatry, 1980, Volume: 137, Issue:5

    Topics: Baclofen; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged

1980
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
    Clinical neuropharmacology, 1993, Volume: 16, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agent

1993
Baclofen-induced dyskinesia.
    Archives of physical medicine and rehabilitation, 1993, Volume: 74, Issue:7

    Topics: Aged; Baclofen; Dyskinesia, Drug-Induced; Humans; Male

1993
Risks of electronic publishing.
    Journal of neurology, 1997, Volume: 244, Issue:1

    Topics: Baclofen; Dyskinesia, Drug-Induced; Dystonia; Humans; Injections, Spinal; Publishing; Word Processin

1997
Tardive dyskinesia.
    Lancet (London, England), 1979, Sep-01, Volume: 2, Issue:8140

    Topics: Antipsychotic Agents; Baclofen; Benzodiazepines; Choline; Dyskinesia, Drug-Induced; Humans; Pimozide

1979
[Tardive dyskinesia. Synthetic-critical review and case contribution].
    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma, 1977, Volume: 48, Issue:1

    Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Di

1977
Treatment-resistant tardive dyskinesia: a new therapeutic approach.
    The American journal of psychiatry, 1979, Volume: 136, Issue:9

    Topics: Aminobutyrates; Baclofen; Deanol; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Ethanolamines

1979
The relationship between parkinsonism and tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Age Factors; Aminobutyrates; Baclofen; Basal Ganglia; Biperiden; Choline; Dopamine; Dyskinesia, Drug

1977
Tardive dystonia: four case histories.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:1

    Topics: Adult; Antipsychotic Agents; Baclofen; Benzodiazepines; Bipolar Disorder; Dyskinesia, Drug-Induced;

1990
Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen.
    Italian journal of neurological sciences, 1990, Volume: 11, Issue:6

    Topics: Baclofen; Causalgia; Clonazepam; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans;

1990
Prevalence of tardive dystonia.
    Acta psychiatrica Scandinavica, 1986, Volume: 73, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Baclofen; Cross-Sectional Studies; Dementia; Drug Therapy, Combin

1986
Orofacial dyskinesia induced by baclofen in a patient with hypothyroidism.
    Clinical pharmacy, 1986, Volume: 5, Issue:2

    Topics: Baclofen; Dyskinesia, Drug-Induced; Facial Paralysis; Female; Humans; Hypothyroidism; Middle Aged

1986