baclofen has been researched along with Drug Overdose in 76 studies
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Baclofen toxicity results from intentional self-poisoning (acute baclofen poisoning) or accumulation of therapeutic dose in the setting of impaired kidney function." | 9.12 | Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning. ( Berling, I; Doi, K; Galvao, T; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Lewington, A; Nolin, TD; Roberts, DM, 2021) |
| "Baclofen self-poisoning by alcohol-dependent patients is a serious concern for the French health authorities." | 7.85 | Self-poisoning with baclofen in alcohol-dependent patients: national reports to French Poison Control Centers, 2008-2013. ( Cardona, F; de Haro, L; Franchitto, N; Pelissier, F; Picot, C; Puskarczyk, E; Sapori, JM; Tournoud, C, 2017) |
| "The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug." | 7.78 | Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012) |
| "Baclofen toxicity can be a cause of profound coma with brainstem dysfunction mimicking brain death, and is mainly a clinical diagnosis." | 7.70 | Coma mimicking brain death following baclofen overdose. ( Nicolle, MW; Ostermann, ME; Sibbald, WJ; Young, B, 2000) |
| "This includes profound lethargy and coma, loss of basic brainstem reflexes and pupil reactivity, myoclonic jerks and seizures, and a burst suppression pattern on EEG." | 5.72 | Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery. ( Betten, DP; McGowan, JD, 2022) |
| "The child presented with respiratory failure, coma, hypotonia and bradycardia." | 5.56 | Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020) |
| "Baclofen is an agonist of peripheral and central B gamma-aminobutyric acid receptors, whose activation causes a myorelaxation and a powerfull depression of the central nervous system." | 5.43 | Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus. ( Aries, P; Di Constanzo, L; Drouillard, I; Montelescaut, É; Pessey, F; Sapin, J; Thill, C; Vaillant, C, 2016) |
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 5.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| "Baclofen is a γ-aminobutyric acid (GABA) agonist that is commonly prescribed for the treatment of spasticity in children." | 5.40 | An unusual cause of flaccid paralysis and coma: baclofen overdose. ( Caron, E; Morgan, R; Wheless, JW, 2014) |
| "Baclofen toxicity results from intentional self-poisoning (acute baclofen poisoning) or accumulation of therapeutic dose in the setting of impaired kidney function." | 5.12 | Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning. ( Berling, I; Doi, K; Galvao, T; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Lewington, A; Nolin, TD; Roberts, DM, 2021) |
| "Baclofen self-poisoning by alcohol-dependent patients is a serious concern for the French health authorities." | 3.85 | Self-poisoning with baclofen in alcohol-dependent patients: national reports to French Poison Control Centers, 2008-2013. ( Cardona, F; de Haro, L; Franchitto, N; Pelissier, F; Picot, C; Puskarczyk, E; Sapori, JM; Tournoud, C, 2017) |
| "The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug." | 3.78 | Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012) |
| "Intrathecal baclofen therapy is increasingly used to alleviate medically intractable spasticity in children with cerebral palsy, spinal cord injuries, and generalized dystonia." | 3.73 | Intrathecal baclofen overdose followed by withdrawal: clinical and EEG features. ( Adirim, TA; Darbari, FP; Kothare, SV; Melvin, JJ; Piatt, JH, 2005) |
| "Intrathecal baclofen (ITB) therapy is being used increasingly to treat medically intractable spasticity in children with cerebral palsy and spinal cord injuries." | 3.73 | Intrathecal baclofen overdose and withdrawal. ( Adirim, TA; Kothare, S; Piatt, JH; Shirley, KW, 2006) |
| "Baclofen overdose may result in coma, apnea, autonomic disturbances, cardiac conduction abnormalities, and seizures." | 3.70 | Baclofen overdose: drug experimentation in a group of adolescents. ( Perry, HE; Shannon, MW; Woolf, AD; Wright, RO, 1998) |
| "Baclofen toxicity can be a cause of profound coma with brainstem dysfunction mimicking brain death, and is mainly a clinical diagnosis." | 3.70 | Coma mimicking brain death following baclofen overdose. ( Nicolle, MW; Ostermann, ME; Sibbald, WJ; Young, B, 2000) |
| "Baclofen was detected in plasma and urine, at 420 ng/mL and 64 900 ng/mL respectively." | 2.66 | Baclofen overdose following recreational use in adolescents and young adults: A case report and review of the literature. ( Abbara, C; Beloncle, F; Briet, M; Drevin, G; Ghamrawi, S, 2020) |
| "Baclofen is a muscle relaxant used in both adults and children with neuromuscular disorders to control spasticity." | 2.41 | Baclofen overdose in two siblings. ( Chapple, D; Connors, R; Johnson, D, 2001) |
| "Agitation, convulsions and ataxia were also seen." | 2.39 | Baclofen poisoning in children. ( Cooke, DE; Glasstone, MA, 1994) |
| " The 5 events during continuous infusion intoxication only happened in high dosed patients." | 2.38 | Intrathecal baclofen overdose: report of 7 events in 5 patients and review of the literature. ( Brouwers, JR; Delhaas, EM, 1991) |
| "This includes profound lethargy and coma, loss of basic brainstem reflexes and pupil reactivity, myoclonic jerks and seizures, and a burst suppression pattern on EEG." | 1.72 | Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery. ( Betten, DP; McGowan, JD, 2022) |
| "The child presented with respiratory failure, coma, hypotonia and bradycardia." | 1.56 | Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020) |
| "Baclofen toxicity can produce an acute encephalopathy even at modest doses, with the EEG showing generalized slowing and triphasic waves consistent with a toxic encephalopathy." | 1.51 | Baclofen Neurotoxicity: A Metabolic Encephalopathy Susceptible to Exacerbation by Benzodiazepine Therapy. ( Dunne, JW; Lawn, ND; Triplett, JD, 2019) |
| "Baclofen has gained interest in treating alcohol use disorder patients." | 1.46 | Baclofen Self-Poisoning in the Era of Changing Indication: Multicentric Reports to a French Poison Control Centre. ( Boels, D; Brunet, M; Le Roux, G; Léger, M; Lerolle, N, 2017) |
| "Baclofen is an agonist of peripheral and central B gamma-aminobutyric acid receptors, whose activation causes a myorelaxation and a powerfull depression of the central nervous system." | 1.43 | Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus. ( Aries, P; Di Constanzo, L; Drouillard, I; Montelescaut, É; Pessey, F; Sapin, J; Thill, C; Vaillant, C, 2016) |
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 1.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| " The lack of proper recommendations regarding the dosage has important implications for safety in clinical management." | 1.42 | High doses of Baclofen as suicide attempt in patients with alcohol use disorders - A serious concern. ( Baby, S; Chand, P; Gowda, GS; Holla, B; Murthy, P; Prabhu, L; Viswanath, B, 2015) |
| "Baclofen is a γ-aminobutyric acid (GABA) agonist that is commonly prescribed for the treatment of spasticity in children." | 1.40 | An unusual cause of flaccid paralysis and coma: baclofen overdose. ( Caron, E; Morgan, R; Wheless, JW, 2014) |
| "Conclusion." | 1.38 | Baclofen overdose mimicking brain death. ( Hodgman, MJ; Kao, L; Sullivan, R; Tormoehlen, LM, 2012) |
| "A 12-year-old girl suffering from spastic diplegia was implanted with a Medtronic SynchroMed II pump (Medtronic Inc." | 1.36 | Malfunction of SynchroMed II baclofen pump delivers a near-lethal baclofen overdose. ( Charalambides, C; Kostopanagiotou, G; Matsota, P; Sgouros, S; Tsangaris, I, 2010) |
| "An 11-year-old boy with spasticity and apallic syndrome needed general anesthesia for exchange of a baclofen pump but 2 h later he became increasingly hypothermic, hypotonic with bradycardy and dyspnea." | 1.35 | [Intrathecal baclofen therapy. Overdose during replacement of a medication pump]. ( Koulousakis, A; Kramer, K; Krep, H; Lier, H; Weber, M, 2009) |
| "The patient became comatose and, as a result of the baclofen dosage being left unchanged despite a deterioration leading to renal failure due to hypotension, the concentration of baclofen was determined to be in the toxic range (0." | 1.34 | Haemodialysis clearance of baclofen. ( Brvar, M; Bunc, M; Kovac, D; Kozelj, G; Pezdir, T; Vrtovec, M, 2007) |
| "Acute respiratory failure which required mechanical ventilation was observed in 18 cases (34." | 1.33 | Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005) |
| "Baclofen has become increasingly popular in the treatment of spasticity disorders." | 1.33 | An unusual presentation of baclofen overdose. ( Chong, CF; Wang, TL, 2005) |
| "Coma, delirium and seizures occurred only with doses of 200 mg or more, and hypertension was more common with higher doses." | 1.33 | Baclofen overdose: defining the spectrum of toxicity. ( Isbister, GK; Leung, NY; Whyte, IM, 2006) |
| "Baclofen was identified in urine by gas chromatography/mass spectrometry." | 1.28 | Toxicological analysis of a fatal baclofen (Lioresal) ingestion. ( Fraser, AD; Isner, AF; MacNeil, W, 1991) |
| " The 18 patients selected for chronic administration were implanted with a programmable pump." | 1.28 | Chronic intrathecal baclofen administration for control of severe spasticity. ( Bastide, R; Carillo, JP; Lazorthes, Y; Sallerin-Caute, B; Verdie, JC, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (23.68) | 18.2507 |
| 2000's | 24 (31.58) | 29.6817 |
| 2010's | 28 (36.84) | 24.3611 |
| 2020's | 6 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| McGowan, JD | 1 |
| Betten, DP | 1 |
| Phu, PJJ | 1 |
| Looi, JCL | 1 |
| Nair, PC | 1 |
| Allison, S | 1 |
| Chan, SKW | 1 |
| Bastiampillai, T | 1 |
| de Marcellus, C | 1 |
| le Bot, S | 1 |
| Decleves, X | 2 |
| Baud, F | 1 |
| Renolleau, S | 1 |
| Oualha, M | 1 |
| Dasgupta, K | 1 |
| Nielson, S | 1 |
| Lee, VR | 1 |
| Shively, RM | 1 |
| Connolly, MK | 1 |
| Hoffman, RS | 2 |
| Nogar, J | 1 |
| Drevin, G | 1 |
| Briet, M | 1 |
| Ghamrawi, S | 1 |
| Beloncle, F | 1 |
| Abbara, C | 1 |
| Ghannoum, M | 1 |
| Berling, I | 1 |
| Lavergne, V | 1 |
| Roberts, DM | 1 |
| Galvao, T | 1 |
| Nolin, TD | 1 |
| Lewington, A | 1 |
| Doi, K | 1 |
| Gosselin, S | 1 |
| Léger, M | 1 |
| Brunet, M | 1 |
| Le Roux, G | 1 |
| Lerolle, N | 1 |
| Boels, D | 1 |
| Chartier, M | 1 |
| Malissin, I | 1 |
| Tannous, S | 1 |
| Labat, L | 2 |
| Risède, P | 1 |
| Mégarbane, B | 2 |
| Chevillard, L | 1 |
| Jamshidi, N | 1 |
| Morley, KC | 1 |
| Cairns, R | 1 |
| Dawson, A | 1 |
| Haber, PS | 1 |
| Triplett, JD | 1 |
| Lawn, ND | 1 |
| Dunne, JW | 1 |
| Caron, E | 1 |
| Morgan, R | 1 |
| Wheless, JW | 1 |
| Masi, G | 1 |
| Mucci, M | 1 |
| Liboni, F | 1 |
| Ferrari, A | 1 |
| Sicca, F | 1 |
| Pommier, P | 1 |
| Debaty, G | 1 |
| Bartoli, M | 1 |
| Viglino, D | 1 |
| Carpentier, F | 1 |
| Danel, V | 1 |
| Maxime, M | 1 |
| Pape, E | 1 |
| Roman, E | 1 |
| Scala-Bertola, J | 1 |
| Thivilier, C | 1 |
| Javot, L | 1 |
| Saint-Marcoux, F | 1 |
| Jouzeau, JY | 1 |
| Gambier, N | 1 |
| Meulendijks, D | 1 |
| Khan, S | 1 |
| Koks, CH | 1 |
| Huitema, AD | 1 |
| Schellens, JH | 1 |
| Beijnen, JH | 1 |
| Davanzo, JR | 1 |
| Rizk, E | 1 |
| Holla, B | 1 |
| Gowda, GS | 1 |
| Prabhu, L | 1 |
| Baby, S | 1 |
| Viswanath, B | 1 |
| Chand, P | 1 |
| Murthy, P | 1 |
| Reichmuth, P | 1 |
| Blanc, AL | 1 |
| Tagan, D | 1 |
| Charifou, Y | 1 |
| Martinet, O | 2 |
| Jabot, J | 1 |
| Gauzere, BA | 2 |
| Allyn, J | 1 |
| Vandroux, D | 2 |
| Thill, C | 1 |
| Di Constanzo, L | 1 |
| Pessey, F | 1 |
| Aries, P | 1 |
| Montelescaut, É | 1 |
| Sapin, J | 1 |
| Vaillant, C | 1 |
| Drouillard, I | 1 |
| de Witte, LD | 1 |
| Dekker, D | 1 |
| Veraart, J | 1 |
| Kromkamp, M | 1 |
| Kaasjager, K | 1 |
| Vinkers, CH | 1 |
| Pelissier, F | 1 |
| de Haro, L | 1 |
| Cardona, F | 1 |
| Picot, C | 1 |
| Puskarczyk, E | 1 |
| Sapori, JM | 1 |
| Tournoud, C | 1 |
| Franchitto, N | 1 |
| Silversides, JA | 1 |
| Scott, KC | 1 |
| Kramer, K | 1 |
| Weber, M | 1 |
| Koulousakis, A | 1 |
| Lier, H | 1 |
| Krep, H | 1 |
| Anand, JS | 1 |
| Habrat, B | 1 |
| Sut, M | 1 |
| Korolkiewicz, R | 1 |
| Sgouros, S | 1 |
| Charalambides, C | 1 |
| Matsota, P | 1 |
| Tsangaris, I | 1 |
| Kostopanagiotou, G | 1 |
| Montes, MI | 1 |
| Hernández Ortiz, OH | 1 |
| Guerra Palacio, A | 1 |
| Nielsen, SU | 1 |
| Jansen, T | 1 |
| Johansen, SS | 1 |
| Linnet, K | 1 |
| Gregersen, P | 1 |
| Høgberg, LC | 1 |
| Quiñones Ortiz, L | 1 |
| Suárez Laurés, A | 1 |
| Pobes Martínez, A | 1 |
| de la Torre, M | 1 |
| Torres Lacalle, A | 1 |
| Forascepi Roza, R | 1 |
| Skjei, KL | 1 |
| Kessler, SK | 1 |
| Abend, NS | 1 |
| Watve, SV | 1 |
| Sivan, M | 1 |
| Raza, WA | 1 |
| Jamil, FF | 1 |
| Sauneuf, B | 1 |
| Totouom, HK | 1 |
| Savary, B | 1 |
| Varin, L | 1 |
| Dupeyrat, J | 1 |
| Ramakers, S | 1 |
| Hanouz, JL | 1 |
| Sullivan, R | 1 |
| Hodgman, MJ | 1 |
| Kao, L | 1 |
| Tormoehlen, LM | 1 |
| Weißhaar, GF | 1 |
| Hoemberg, M | 1 |
| Bender, K | 1 |
| Bangen, U | 1 |
| Herkenrath, P | 1 |
| Eifinger, F | 1 |
| Rothschild, M | 1 |
| Roth, B | 1 |
| Oberthuer, A | 1 |
| Lyew, MA | 1 |
| Mondy, C | 1 |
| Eagle, S | 1 |
| Chernich, SE | 1 |
| Dawes, WJ | 1 |
| Drake, JM | 1 |
| Fehlings, D | 1 |
| Delhaas, E | 1 |
| Goslinga, S | 1 |
| Martin, TW | 1 |
| Mayhew, JF | 1 |
| Yeh, RN | 1 |
| Nypaver, MM | 1 |
| Deegan, TJ | 1 |
| Ayyangar, R | 1 |
| Gerçek, A | 1 |
| Baykan, N | 1 |
| Dağçinar, A | 1 |
| Ozek, MM | 1 |
| Wu, VC | 1 |
| Lin, SL | 1 |
| Lin, SM | 1 |
| Fang, CC | 1 |
| Lew, SM | 1 |
| Psaty, EL | 1 |
| Abbott, R | 1 |
| Dario, A | 1 |
| Scamoni, C | 1 |
| Picano, M | 1 |
| Casagrande, F | 1 |
| Tomei, G | 1 |
| Chong, CF | 1 |
| Wang, TL | 1 |
| Sein Anand, J | 1 |
| Chodorowski, Z | 1 |
| Burda, P | 1 |
| Darbari, FP | 1 |
| Melvin, JJ | 1 |
| Piatt, JH | 2 |
| Adirim, TA | 2 |
| Kothare, SV | 1 |
| Leung, NY | 1 |
| Whyte, IM | 1 |
| Isbister, GK | 1 |
| Shirley, KW | 1 |
| Kothare, S | 1 |
| Wall, GC | 1 |
| Wasiak, A | 1 |
| Hicklin, GA | 1 |
| Brvar, M | 1 |
| Vrtovec, M | 1 |
| Kovac, D | 1 |
| Kozelj, G | 1 |
| Pezdir, T | 1 |
| Bunc, M | 1 |
| Dalton, C | 1 |
| Keenan, E | 1 |
| Stevenson, V | 1 |
| Mack, RB | 1 |
| Cooke, DE | 1 |
| Glasstone, MA | 1 |
| Kozak, G | 1 |
| Roberge, RJ | 1 |
| Martin, TG | 1 |
| Hodgman, M | 1 |
| Benitez, JG | 1 |
| Brunswick, JE | 1 |
| Azouvi, P | 1 |
| Mane, M | 1 |
| Thiebaut, JB | 1 |
| Denys, P | 1 |
| Remy-Neris, O | 1 |
| Bussel, B | 1 |
| Broggi, G | 1 |
| Dones, I | 1 |
| Servello, D | 1 |
| Ferrazza, C | 1 |
| Dressnandt, J | 1 |
| Weinzierl, FX | 1 |
| Tölle, TR | 1 |
| Konstanzer, A | 1 |
| Conrad, B | 1 |
| Chern, TL | 1 |
| Kwan, A | 1 |
| Perry, HE | 1 |
| Wright, RO | 1 |
| Shannon, MW | 1 |
| Woolf, AD | 1 |
| Peng, CT | 1 |
| Ger, J | 1 |
| Yang, CC | 1 |
| Tsai, WJ | 1 |
| Deng, JF | 1 |
| Bullard, MJ | 1 |
| Rushman, S | 1 |
| McLaren, I | 1 |
| Ostermann, ME | 1 |
| Young, B | 1 |
| Sibbald, WJ | 1 |
| Nicolle, MW | 1 |
| Chapple, D | 1 |
| Johnson, D | 1 |
| Connors, R | 1 |
| McDonald, NJ | 1 |
| Festa, MS | 1 |
| Wilkins, B | 1 |
| Ivanhoe, CB | 1 |
| Tilton, AH | 1 |
| Francisco, GE | 1 |
| Saltuari, L | 2 |
| Marosi, MJ | 1 |
| Kofler, M | 2 |
| Bauer, G | 1 |
| Schmutzhard, E | 1 |
| Berek, K | 1 |
| Baumgartner, H | 1 |
| Russegger, L | 1 |
| Aichner, F | 1 |
| Teddy, P | 1 |
| Jamous, A | 1 |
| Gardner, B | 1 |
| Wang, D | 1 |
| Silver, J | 1 |
| Weissenborn, K | 1 |
| Wilkens, H | 1 |
| Hausmann, E | 1 |
| Degen, PH | 1 |
| Delhaas, EM | 1 |
| Brouwers, JR | 1 |
| Fraser, AD | 1 |
| MacNeil, W | 1 |
| Isner, AF | 1 |
| Lazorthes, Y | 1 |
| Sallerin-Caute, B | 1 |
| Verdie, JC | 1 |
| Bastide, R | 1 |
| Carillo, JP | 1 |
10 reviews available for baclofen and Drug Overdose
| Article | Year |
|---|---|
Psychosis Related to Baclofen Withdrawal or Overdose: A Systematic Review.
Topics: Antipsychotic Agents; Baclofen; Drug Overdose; Humans; Psychotic Disorders; Substance Withdrawal Syn | 2023 |
Report of severe accidental baclofen intoxication in a healthy 4-year-old boy and review of the literature.
Topics: Baclofen; Child, Preschool; Coma; Drug Overdose; Humans; Male; Severity of Illness Index | 2019 |
Baclofen overdose following recreational use in adolescents and young adults: A case report and review of the literature.
Topics: Adolescent; Baclofen; Chromatography, Liquid; Drug Overdose; GABA-B Receptor Agonists; Humans; Male; | 2020 |
Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning.
Topics: Baclofen; Cohort Studies; Drug Overdose; Humans; Poisoning; Renal Dialysis; Seizures | 2021 |
Management of acute overdose or withdrawal state in intrathecal baclofen therapy.
Topics: Adult; Baclofen; Benzodiazepines; Drug Overdose; Humans; Infusion Pumps, Implantable; Substance With | 2012 |
Pharmacological complications of the chronic baclofen infusion in the severe spinal spasticity. Personal experience and review of the literature.
Topics: Adult; Baclofen; Constipation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug | 2004 |
Baclofen poisoning in children.
Topics: Ataxia; Baclofen; Central Nervous System; Child; Child, Preschool; Cohort Studies; Drug Overdose; Fe | 1994 |
Baclofen overdose in two siblings.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Drug Overdose; Family Health; Humans; Infant; Mus | 2001 |
Intrathecal baclofen therapy for spastic hypertonia.
Topics: Baclofen; Cerebral Palsy; Drug Overdose; GABA Agonists; Humans; Injections, Spinal; Multiple Scleros | 2001 |
Intrathecal baclofen overdose: report of 7 events in 5 patients and review of the literature.
Topics: Adult; Aged; Baclofen; Drug Overdose; Female; Humans; Injections, Spinal; Male; Muscle Spasticity; P | 1991 |
1 trial available for baclofen and Drug Overdose
| Article | Year |
|---|---|
Intrathecal baclofen administration for control of severe spinal spasticity: functional improvement and long-term follow-up.
Topics: Activities of Daily Living; Adult; Baclofen; Drug Overdose; Female; Follow-Up Studies; Humans; Infus | 1996 |
65 other studies available for baclofen and Drug Overdose
| Article | Year |
|---|---|
Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery.
Topics: Baclofen; Brain Stem; Coma; Drug Overdose; Electroencephalography; Female; Humans; Middle Aged | 2022 |
Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen.
Topics: Adult; Baclofen; Child, Preschool; Coma; Drug Overdose; Female; Humans; Muscle Relaxants, Central; R | 2020 |
Removal of baclofen with hemodialysis is negligible compared to intact kidney excretion in a pediatric overdose: a case report.
Topics: Adolescent; Baclofen; Drug Overdose; Emergency Service, Hospital; Female; Humans; Kidney; Renal Dial | 2021 |
Baclofen Self-Poisoning in the Era of Changing Indication: Multicentric Reports to a French Poison Control Centre.
Topics: Adult; Alcoholism; Baclofen; Drug Overdose; Female; France; Humans; Male; Middle Aged; Muscle Relaxa | 2017 |
Baclofen-induced encephalopathy in overdose - Modeling of the electroencephalographic effect/concentration relationships and contribution of tolerance in the rat.
Topics: Animals; Baclofen; Brain; Brain Diseases; Dose-Response Relationship, Drug; Drug Overdose; Drug Tole | 2018 |
A Review of Baclofen Overdoses in Australia: Calls to a Poisons Information Centre and a Case Series.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Baclofen; Databases, Factual; Drug Overdose; | 2019 |
Baclofen Neurotoxicity: A Metabolic Encephalopathy Susceptible to Exacerbation by Benzodiazepine Therapy.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Benzodiazepines; Brain Diseases, Metabolic; Drug Overdose; | 2019 |
An unusual cause of flaccid paralysis and coma: baclofen overdose.
Topics: Adolescent; Baclofen; Central Nervous System; Coma; Drug Overdose; Epilepsy, Generalized; Female; Hu | 2014 |
Self-induced multiple comas with recreational baclofen overdoses in an adolescent girl.
Topics: Adolescent; Baclofen; Coma; Diagnostic Errors; Drug Overdose; Female; Humans; Muscle Relaxants, Cent | 2013 |
Severity of deliberate acute baclofen poisoning: a nonconcurrent cohort study.
Topics: Adult; Alcoholism; Baclofen; Dose-Response Relationship, Drug; Drug Overdose; Endpoint Determination | 2014 |
Death of an alcohol-dependent patient following intentional drug intoxication: implication of baclofen?
Topics: Alcoholism; Antipruritics; Baclofen; Central Nervous System Depressants; Drug Overdose; Ethanol; Fat | 2014 |
Baclofen overdose treated with continuous venovenous hemofiltration.
Topics: Baclofen; Drug Overdose; Hemofiltration; Humans; Metabolic Clearance Rate; Middle Aged; Muscle Relax | 2015 |
Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump.
Topics: Baclofen; Cerebral Palsy; Child; Device Removal; Drug Overdose; Equipment Failure; GABA-B Receptor A | 2015 |
High doses of Baclofen as suicide attempt in patients with alcohol use disorders - A serious concern.
Topics: Adult; Alcoholism; Baclofen; Drug Overdose; Humans; Male; Muscle Relaxants, Central; Suicide, Attemp | 2015 |
Unintentional baclofen intoxication in the management of alcohol use disorder.
Topics: Aged; Alcohol-Related Disorders; Baclofen; Delirium; Disease Management; Drug Overdose; Hallucinatio | 2015 |
Baclofen intoxication cases in an intensive care unit.
Topics: Adult; Aged; Baclofen; Critical Care; Drug Overdose; Female; France; Hemofiltration; Humans; Intensi | 2016 |
Is extracorporeal treatment useful for managing severe baclofen poisoning? - The debate is still open.
Topics: Baclofen; Drug Overdose; Female; Hemofiltration; Humans; Male; Middle Aged; Muscle Relaxants, Centra | 2016 |
Is extracorporeal treatment useful for managing severe baclofen poisoning even on patients with normal renal function? Indeed a very open debate!
Topics: Baclofen; Critical Care; Drug Overdose; Humans; Kidney; Muscle Relaxants, Central; Renal Dialysis | 2016 |
Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus.
Topics: Baclofen; Coma; Drug Overdose; Female; France; Humans; Middle Aged; Muscle Hypotonia; Self-Injurious | 2016 |
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans; | 2016 |
Self-poisoning with baclofen in alcohol-dependent patients: national reports to French Poison Control Centers, 2008-2013.
Topics: Adolescent; Adult; Aged; Alcoholism; Baclofen; Cause of Death; Dose-Response Relationship, Drug; Dru | 2017 |
Diabetes insipidus following overdose of baclofen and quetiapine.
Topics: Baclofen; Diabetes Insipidus; Dibenzothiazepines; Drug Overdose; Humans; Male; Middle Aged; Quetiapi | 2009 |
[Intrathecal baclofen therapy. Overdose during replacement of a medication pump].
Topics: Anesthesia, General; Baclofen; Cerebral Palsy; Child; Drug Overdose; Humans; Infusion Pumps, Implant | 2009 |
[Misuse of substances theoretically without abuse potential--case series].
Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Antidepressive Agents; Baclofen; Benzydamine; C | 2009 |
Malfunction of SynchroMed II baclofen pump delivers a near-lethal baclofen overdose.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Equipment Failure; Female; Humans; Infusion Pumps, I | 2010 |
[Electroencephalographic burst-suppression pattern due to baclofen intoxication].
Topics: Baclofen; Coma; Drug Overdose; Electroencephalography; Emergencies; Fatal Outcome; Female; Humans; I | 2011 |
[Venovenous hemodiafiltration for patient with baclofen intoxication].
Topics: Baclofen; Drug Overdose; Half-Life; Hemofiltration; Humans; Male; Muscle Relaxants, Central; Suicide | 2011 |
Warning against unexpected medication in haemodialysis.
Topics: Acyclovir; Aged; Akathisia, Drug-Induced; Alcoholic Intoxication; Baclofen; Continuity of Patient Ca | 2011 |
Stimulus-induced rhythmic, periodic, or ictal discharges in a 13-year-old girl after an overdose and respiratory arrest.
Topics: Adolescent; Baclofen; Bupropion; Drug Overdose; Female; Heart Arrest; Humans; Periodicity; Seizures | 2011 |
Clinical and EEG features of acute intrathecal baclofen overdose.
Topics: Baclofen; Drug Overdose; Electroencephalography; Ependymoma; Equipment Failure; GABA Agonists; Glasg | 2012 |
Baclofen overdose mimicking brain death.
Topics: Adult; Baclofen; Brain Death; Drug Overdose; Electroencephalography; Female; Humans; Middle Aged | 2012 |
Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature.
Topics: Adolescent; Baclofen; Bradycardia; Coma; Drug Overdose; Humans; Male; Muscle Relaxants, Central; Sei | 2012 |
Hemodynamic instability and delayed emergence from general anesthesia associated with inadvertent intrathecal baclofen overdose.
Topics: Anesthesia Recovery Period; Anesthesia, General; Baclofen; Blood Pressure; Child; Drug Overdose; Hea | 2003 |
Microfracture of a baclofen pump catheter with intermittent under- and overdose.
Topics: Baclofen; Catheters, Indwelling; Child; Dose-Response Relationship, Drug; Drug Overdose; Equipment F | 2003 |
Baclofen pumps: comment on Anderson et al.
Topics: Baclofen; Child; Coma; Drug Overdose; GABA Agonists; Humans; Infusion Pumps, Implantable; Medication | 2003 |
Baclofen, hemodynamic instability and delayed emergence: our perspective.
Topics: Anesthesia Recovery Period; Baclofen; Drug Overdose; Hemodynamics; Humans; Muscle Relaxants, Central | 2003 |
Baclofen toxicity in an 8-year-old with an intrathecal baclofen pump.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Equipment Design; Equipment Failure; Equipment Failu | 2004 |
Does general anesthesia potentiate the GABA-ergic action of intrathecal baclofen?
Topics: Adolescent; Anesthesia, General; Baclofen; Drug Overdose; Drug Synergism; Electrocardiography; GABA | 2004 |
Treatment of baclofen overdose by haemodialysis: a pharmacokinetic study.
Topics: Aged; Baclofen; Drug Overdose; Female; Humans; Kidney Failure, Chronic; Muscle Relaxants, Central; R | 2005 |
An unusual cause of overdose after baclofen pump implantation: case report.
Topics: Adolescent; Baclofen; Cerebral Palsy; Consciousness Disorders; Contrast Media; Drug Overdose; Dyston | 2005 |
An unusual presentation of baclofen overdose.
Topics: Adult; Amyotrophic Lateral Sclerosis; Baclofen; Delirium; Drug Overdose; Humans; Male; Muscle Relaxa | 2005 |
Selected clinical aspects of acute intoxication with baclofen.
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal | 2005 |
Intrathecal baclofen overdose followed by withdrawal: clinical and EEG features.
Topics: Baclofen; Brain Diseases; Cerebral Palsy; Child; Drug Overdose; Electroencephalography; Humans; Inje | 2005 |
Baclofen overdose: defining the spectrum of toxicity.
Topics: Adolescent; Adult; Age Distribution; Australia; Baclofen; Cardiovascular Diseases; Consciousness Dis | 2006 |
Intrathecal baclofen overdose and withdrawal.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Humans; Infusion Pumps, Implantable; Injections, Spi | 2006 |
An initially unsuspected case of baclofen overdose.
Topics: Baclofen; Coma; Drug Overdose; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Muscle Relaxants, | 2006 |
Haemodialysis clearance of baclofen.
Topics: Acute Kidney Injury; Area Under Curve; Baclofen; Coma; Drug Overdose; GABA Agonists; Humans; Male; M | 2007 |
A novel cause of intrathecal baclofen overdosage: lessons to be learnt.
Topics: Baclofen; Drug Overdose; Drug Therapy, Computer-Assisted; Female; GABA Agonists; Humans; Infusion Pu | 2008 |
Between a rock and a Charybdisian place. Baclofen (Lioresal) overdose.
Topics: Adult; Baclofen; Child; Drug Overdose; Humans; Mythology | 1995 |
[Six cases of baclofen poisoning--clinical course and evaluation of conventional treatment and hemodialysis].
Topics: Adolescent; Adult; Baclofen; Drug Overdose; Female; Humans; Male; Renal Dialysis; Suicide, Attempted | 1994 |
Supraventricular tachyarrhythmia associated with baclofen overdose.
Topics: Adenosine; Adult; Baclofen; Drug Overdose; Electrocardiography; Humans; Intubation, Intratracheal; M | 1994 |
A possible pharmacological treatment of baclofen overdose.
Topics: Baclofen; Drug Overdose; Female; Humans; Middle Aged; Serotonin Antagonists | 1996 |
Acute overdose of intrathecal baclofen.
Topics: Adult; Baclofen; Drug Overdose; Female; Humans; Infusion Pumps; Injections, Spinal; Medication Error | 1996 |
Flumazenil-induced seizure accompanying benzodiazepine and baclofen intoxication.
Topics: Adult; Antidotes; Baclofen; Benzodiazepines; Drug Interactions; Drug Overdose; Female; Flumazenil; H | 1996 |
Baclofen overdose: drug experimentation in a group of adolescents.
Topics: Adolescent; Apnea; Baclofen; Coma; Drug Overdose; Female; GABA Agonists; Humans; Male; Muscle Relaxa | 1998 |
Prolonged severe withdrawal symptoms after acute-on-chronic baclofen overdose.
Topics: Adult; Baclofen; Cardiovascular Diseases; Drug Overdose; Humans; Male; Muscle Relaxants, Central; Ne | 1998 |
Management of intra-thecal baclofen overdose.
Topics: Antidotes; Baclofen; Drug Overdose; Equipment Failure; Female; GABA Agonists; Humans; Infusion Pumps | 1999 |
Coma mimicking brain death following baclofen overdose.
Topics: Baclofen; Brain Death; Coma; Diagnosis, Differential; Drug Overdose; Humans; Male; Middle Aged; Musc | 2000 |
Teenage coma.
Topics: Adolescent; Baclofen; Coma; Drug Overdose; Humans; Male; Muscle Relaxants, Central | 2001 |
Status epilepticus complicating intrathecal baclofen overdose.
Topics: Adolescent; Animals; Baclofen; Drug Overdose; Humans; Rats; Status Epilepticus | 1992 |
Electrophysiological findings in a case of severe intrathecal baclofen overdose.
Topics: Adolescent; Baclofen; Drug Overdose; Electric Stimulation; Electroencephalography; Evoked Potentials | 1992 |
Complications of intrathecal baclofen delivery.
Topics: Adolescent; Adult; Baclofen; Drug Overdose; Female; Follow-Up Studies; Humans; Infusion Pumps, Impla | 1992 |
Burst suppression EEG with baclofen overdose.
Topics: Adult; Baclofen; Coma; Drug Overdose; Electroencephalography; Female; Humans; Suicide, Attempted | 1991 |
Toxicological analysis of a fatal baclofen (Lioresal) ingestion.
Topics: Adult; Baclofen; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Overdose; Ga | 1991 |
Chronic intrathecal baclofen administration for control of severe spasticity.
Topics: Baclofen; Coma; Drug Overdose; Drug Tolerance; Evaluation Studies as Topic; Humans; Infusion Pumps, | 1990 |