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baclofen and Disease Exacerbation

baclofen has been researched along with Disease Exacerbation in 19 studies

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy."9.13The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008)
"In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome."7.96Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020)
"Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps."7.85Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017)
"To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps."7.85Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017)
"Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy."7.76Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort."7.74The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007)
"Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis."7.74Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007)
"Spasticity is the major etiology for hip dislocation in nonambulatory cerebral palsy patients."5.38A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients. ( Ayyangar, RN; Caird, MS; Craig, CL; Farley, FA; Hensinger, RN; Hurvitz, EA; Nowicki, P; Silva, S; Vanderhave, KL, 2012)
"We report a case of dystonia with a partial deletion of the short arm (p) of chromosome 18 and androgen insensitivity."5.30Progressive dystonia in a child with chromosome 18p deletion, treated with intrathecal baclofen. ( Awaad, Y; Munoz, S; Nigro, M, 1999)
"Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy."5.13The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008)
"In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome."3.96Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020)
"Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps."3.85Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017)
"To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps."3.85Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017)
"Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy."3.76Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort."3.74The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007)
"Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis."3.74Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007)
" They also required higher doses and more rapid dosage increases."2.68Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus. ( Dressnandt, J; Marquardt, G; Mauch, E; Meinck, HM; Müller-Schwefe, G; Rieke, K; Schumm, F; Stayer, C; Tronnier, V, 1997)
"All children are known to have severe dyskinetic cerebral palsy and presented with an acute or sub-acute deterioration in their symptoms."1.43Status dystonicus in children: Early recognition and treatment prevent serious complications. ( Abu-Arafeh, I; Combe, L, 2016)
"Spasticity is the major etiology for hip dislocation in nonambulatory cerebral palsy patients."1.38A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients. ( Ayyangar, RN; Caird, MS; Craig, CL; Farley, FA; Hensinger, RN; Hurvitz, EA; Nowicki, P; Silva, S; Vanderhave, KL, 2012)
"We report a 21-yr-old male patient with spondyloepiphyseal dysplasia tarda with progressive arthropathy who developed spastic paraplegia because of spinal stenosis caused by thoracic disk herniations."1.37Spondyloepiphyseal dysplasia tarda with progressive arthropathy complicated with paraplegia. ( Gelal, F; Memi, A; Olmez, N; Oz, B; Yoleri, O, 2011)
"We report a case of dystonia with a partial deletion of the short arm (p) of chromosome 18 and androgen insensitivity."1.30Progressive dystonia in a child with chromosome 18p deletion, treated with intrathecal baclofen. ( Awaad, Y; Munoz, S; Nigro, M, 1999)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.79)18.2507
2000's6 (31.58)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Lins, LAB1
Nechyporenko, AV1
Halanski, MA1
Hetzel, SJ1
Noonan, KJ1
Walker, KR1
Novotny, SA1
Krach, LE1
Arroyo González, R1
Parigi, L1
Torta, M1
Barbero, R1
Boncristiano, DM1
Clerici, D1
Meduri, E1
Rigano, A1
Vendramin, S1
Rushton, PRP1
Nasto, LA1
Aujla, RK1
Ammar, A1
Grevitt, MP1
Vloeberghs, MH1
Combe, L1
Abu-Arafeh, I1
Morishita, A1
Aihara, H1
Nakai, T1
Adachi, M1
Karneev, AN1
Solov'eva, EIu1
Fedin, AI1
Shilt, JS1
Lai, LP1
Cabrera, MN1
Frino, J1
Smith, BP1
Bonouvrié, LA1
van Schie, PE1
Becher, JG1
van Ouwerkerk, WJ1
Vermeulen, RJ1
Burn, SC1
Zeller, R1
Drake, JM1
Yoleri, O1
Oz, B1
Olmez, N1
Memi, A1
Gelal, F1
Silva, S1
Nowicki, P1
Caird, MS1
Hurvitz, EA1
Ayyangar, RN1
Farley, FA1
Vanderhave, KL1
Hensinger, RN1
Craig, CL1
Hart, AR1
Tripathi, C1
Rowland, DJ1
Broadley, P1
Mordekar, SR1
Senaran, H1
Shah, SA1
Presedo, A1
Dabney, KW1
Glutting, JW1
Miller, F1
Ginsburg, GM1
Lauder, AJ1
Stayer, C1
Tronnier, V1
Dressnandt, J1
Mauch, E1
Marquardt, G2
Rieke, K1
Müller-Schwefe, G1
Schumm, F1
Meinck, HM1
Awaad, Y1
Munoz, S1
Nigro, M1
Lorenz, R1

Reviews

1 review available for baclofen and Disease Exacerbation

ArticleYear
A review of the effects of baclofen and of THC:CBD oromucosal spray on spasticity-related walking impairment in multiple sclerosis.
    Expert review of neurotherapeutics, 2018, Volume: 18, Issue:10

    Topics: Baclofen; Cannabidiol; Disease Progression; Dronabinol; Drug Combinations; Gait Disorders, Neurologi

2018

Trials

3 trials available for baclofen and Disease Exacerbation

ArticleYear
The use of baklosan in the complex treatment of back pain.
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2007, Volume: 107, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Baclofen; Disease Progr

2007
The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy.
    Journal of pediatric orthopedics, 2008, Volume: 28, Issue:6

    Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Disease Progres

2008
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.
    Neurology, 1997, Volume: 49, Issue:6

    Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Cohort Studies; Disease Progression; Female;

1997

Other Studies

15 other studies available for baclofen and Disease Exacerbation

ArticleYear
Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy?
    Spine deformity, 2020, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Disease Progression; Female; Humans; Infusion Pu

2020
Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis?
    Spine deformity, 2017, Volume: 5, Issue:6

    Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Chi-Square Distribution; Child; Disease

2017
Botulism: a case of severe intoxication.
    Minerva anestesiologica, 2014, Volume: 80, Issue:2

    Topics: Baclofen; Botulism; Disease Progression; Humans; Male; Muscle Relaxants, Central; Neurologic Examina

2014
Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017, Volume: 26, Issue:6

    Topics: Baclofen; Case-Control Studies; Cerebral Palsy; Child; Cohort Studies; Disease Progression; Female;

2017
Status dystonicus in children: Early recognition and treatment prevent serious complications.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2016, Volume: 20, Issue:6

    Topics: Adolescent; Anti-Dyskinesia Agents; Athetosis; Baclofen; Cerebral Palsy; Child; Disease Progression;

2016
[A Pediatric Case of Intractable Cerebrospinal Fluid Leakage after Implantation of an Intrathecal Baclofen Pump].
    No shinkei geka. Neurological surgery, 2017, Volume: 45, Issue:1

    Topics: Abdomen; Baclofen; Cerebral Palsy; Cerebrospinal Fluid Leak; Child; Disease Progression; Female; Hum

2017
Satisfaction with intrathecal baclofen treatment in paediatric patients with progressive neurological disease.
    Developmental medicine and child neurology, 2008, Volume: 50, Issue:8

    Topics: Baclofen; Child; Disease Progression; Humans; Injections, Spinal; Muscle Relaxants, Central; Nervous

2008
Do baclofen pumps influence the development of scoliosis in children?
    Journal of neurosurgery. Pediatrics, 2010, Volume: 5, Issue:2

    Topics: Adolescent; Aging; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Dystonia;

2010
Spondyloepiphyseal dysplasia tarda with progressive arthropathy complicated with paraplegia.
    American journal of physical medicine & rehabilitation, 2011, Volume: 90, Issue:6

    Topics: Analgesics; Arthralgia; Baclofen; Disease Progression; Follow-Up Studies; Humans; Low Back Pain; Mal

2011
A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients.
    Journal of pediatric orthopedics, 2012, Volume: 32, Issue:8

    Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; Follow-U

2012
'Rapid progression of scoliosis complicating intrathecal baclofen pump insertion'.
    Developmental medicine and child neurology, 2007, Volume: 49, Issue:9

    Topics: Adolescent; Baclofen; Child; Disease Progression; Female; Humans; Infusion Pumps, Implantable; Injec

2007
The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy.
    Spine, 2007, Oct-01, Volume: 32, Issue:21

    Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; Humans;

2007
Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump.
    Spine, 2007, Nov-15, Volume: 32, Issue:24

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; H

2007
Progressive dystonia in a child with chromosome 18p deletion, treated with intrathecal baclofen.
    Journal of child neurology, 1999, Volume: 14, Issue:2

    Topics: Adolescent; Baclofen; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes

1999
Intrathecal baclofen for intractable spasticity in amyotrophic lateral sclerosis.
    Journal of neurology, 1999, Volume: 246, Issue:7

    Topics: Adult; Amyotrophic Lateral Sclerosis; Baclofen; Catheters, Indwelling; Disease Progression; Dose-Res

1999