Page last updated: 2024-10-23

baclofen and Coma

baclofen has been researched along with Coma in 43 studies

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
"The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug."7.78Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012)
"We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps."7.71Reversible coma in children after improper baclofen pump insertion. ( Anderson, KJ; Brown, K; Farmer, JP, 2002)
"Baclofen toxicity can be a cause of profound coma with brainstem dysfunction mimicking brain death, and is mainly a clinical diagnosis."7.70Coma mimicking brain death following baclofen overdose. ( Nicolle, MW; Ostermann, ME; Sibbald, WJ; Young, B, 2000)
" Five patients developed central depression with coma and respiratory depression, requiring artificial ventilation in 3 cases and reversed by flumazenil in 2 cases."7.68Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. ( Demazière, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"This includes profound lethargy and coma, loss of basic brainstem reflexes and pupil reactivity, myoclonic jerks and seizures, and a burst suppression pattern on EEG."5.72Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery. ( Betten, DP; McGowan, JD, 2022)
"Baclofen (Lioresal) is a derivative of gamma-aminobutyric acid and is used in both adults and children mainly for symptomatic treatment of muscle spasticity."5.56Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020)
"Baclofen is an agonist of peripheral and central B gamma-aminobutyric acid receptors, whose activation causes a myorelaxation and a powerfull depression of the central nervous system."5.43Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus. ( Aries, P; Di Constanzo, L; Drouillard, I; Montelescaut, É; Pessey, F; Sapin, J; Thill, C; Vaillant, C, 2016)
"Baclofen overdose is treated with supportive care and antiepileptic medications as indicated."5.40An unusual cause of flaccid paralysis and coma: baclofen overdose. ( Caron, E; Morgan, R; Wheless, JW, 2014)
"A 33-year-old man with refractory spasticity due to diffuse white matter injury was admitted for ITB treatment."5.33Intrathecal baclofen toxicity and deep coma in minutes. ( Hanci, L; Hanci, M; Hanimoglu, H; Tanriverdi, T; Tunali, Y, 2006)
" Baclofen intoxication is a rare cause of brain death mimic characterised by transient deep coma and absence of brainstem reflexes and might be mistaken with brain death."4.31Neurological evolution of severe baclofen intoxication: from brain death mimic to recovered brain function. ( Berger, S; Fisch, U; Kuster, T; Sutter, R, 2023)
"GABA analogs containing phenyl (phenibut) or para-chlorophenyl (baclofen) substituents demonstrated nootropic activity in a dose of 20 mg/kg: they improved passive avoidance conditioning, decelerated its natural extinction, and exerted antiamnestic effect on the models of amnesia provoked by scopolamine or electroshock."3.83Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid. ( Bagmetova, VV; Berestovitskaya, VM; Borodkina, LE; Tyurenkov, IN; Vasil'eva, OS, 2016)
"The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug."3.78Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012)
"We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps."3.71Reversible coma in children after improper baclofen pump insertion. ( Anderson, KJ; Brown, K; Farmer, JP, 2002)
"Baclofen overdose may result in coma, apnea, autonomic disturbances, cardiac conduction abnormalities, and seizures."3.70Baclofen overdose: drug experimentation in a group of adolescents. ( Perry, HE; Shannon, MW; Woolf, AD; Wright, RO, 1998)
"Baclofen toxicity can be a cause of profound coma with brainstem dysfunction mimicking brain death, and is mainly a clinical diagnosis."3.70Coma mimicking brain death following baclofen overdose. ( Nicolle, MW; Ostermann, ME; Sibbald, WJ; Young, B, 2000)
"We report a case of inadvertent overdose of baclofen given intrathecally resulting in coma."3.69Flumazenil: an unreliable antagonist in baclofen overdose. ( Byrnes, SM; Hardy, PA; Watson, GW, 1996)
" Five patients developed central depression with coma and respiratory depression, requiring artificial ventilation in 3 cases and reversed by flumazenil in 2 cases."3.68Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. ( Demazière, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Baclofen concentration was measured serially during the session."1.91Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog. ( Gabba, L; Iannucci, C; Vigani, A, 2023)
"It is associated with coma and can cause brainstem reflexes to disappear, simulating a brain death-like condition."1.72A Severe Baclofen Intoxication Mimicking Post-Hypoxic Encephalopathy: Wait and See! ( Klijn, AJ; Muntinga, L; Noordergraaf, GJ, 2022)
"This includes profound lethargy and coma, loss of basic brainstem reflexes and pupil reactivity, myoclonic jerks and seizures, and a burst suppression pattern on EEG."1.72Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery. ( Betten, DP; McGowan, JD, 2022)
"ITB led to significant improvement in spasticity based on MAS scores, which did not correlate to the improvements seen in CRS-R total and subscale scores."1.72On the recovery of disorders of consciousness under intrathecal baclofen administration for severe spasticity-An observational study. ( Dobesberger, J; Fava, E; Genelin, E; Halbmayer, LM; Hitzenberger, G; Kofler, M; Matzak, H; Pucks-Faes, E; Saltuari, L; Versace, V; Werkmann, M, 2022)
"Baclofen (Lioresal) is a derivative of gamma-aminobutyric acid and is used in both adults and children mainly for symptomatic treatment of muscle spasticity."1.56Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020)
"Nociception Coma Scale-Revised (NCS-R) also changed from 4 to 8 at the same time points."1.51Late recovery of responsiveness after intra-thecal baclofen pump implantation and the role of diffuse pain and severe spasticity: a case report. ( Aloisi, M; Baldeschi, GC; Buzzi, MG; Cobianchi, MR; Contrada, M; Formisano, R; Niedbala, S; Schiattone, S; Spanedda, F, 2019)
"Baclofen is an agonist of peripheral and central B gamma-aminobutyric acid receptors, whose activation causes a myorelaxation and a powerfull depression of the central nervous system."1.43Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus. ( Aries, P; Di Constanzo, L; Drouillard, I; Montelescaut, É; Pessey, F; Sapin, J; Thill, C; Vaillant, C, 2016)
"Baclofen overdose is treated with supportive care and antiepileptic medications as indicated."1.40An unusual cause of flaccid paralysis and coma: baclofen overdose. ( Caron, E; Morgan, R; Wheless, JW, 2014)
"The patient became comatose and, as a result of the baclofen dosage being left unchanged despite a deterioration leading to renal failure due to hypotension, the concentration of baclofen was determined to be in the toxic range (0."1.34Haemodialysis clearance of baclofen. ( Brvar, M; Bunc, M; Kovac, D; Kozelj, G; Pezdir, T; Vrtovec, M, 2007)
"Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system."1.33Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005)
"A 33-year-old man with refractory spasticity due to diffuse white matter injury was admitted for ITB treatment."1.33Intrathecal baclofen toxicity and deep coma in minutes. ( Hanci, L; Hanci, M; Hanimoglu, H; Tanriverdi, T; Tunali, Y, 2006)
"There was no correlation between the dosage of baclofen and the clinical outcome."1.32[Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004)
" The 18 patients selected for chronic administration were implanted with a programmable pump."1.28Chronic intrathecal baclofen administration for control of severe spasticity. ( Bastide, R; Carillo, JP; Lazorthes, Y; Sallerin-Caute, B; Verdie, JC, 1990)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.95)18.7374
1990's6 (13.95)18.2507
2000's13 (30.23)29.6817
2010's10 (23.26)24.3611
2020's8 (18.60)2.80

Authors

AuthorsStudies
Muntinga, L1
Klijn, AJ1
Noordergraaf, GJ1
McGowan, JD1
Betten, DP1
Halbmayer, LM1
Kofler, M1
Hitzenberger, G1
Matzak, H1
Fava, E1
Genelin, E1
Werkmann, M1
Saltuari, L1
Versace, V1
Dobesberger, J1
Pucks-Faes, E1
Chen, SY1
Chu, FY1
Yang, CY1
Tarng, DC1
Gabba, L2
Iannucci, C2
Vigani, A2
Hodgson, SE2
Wong, A2
Berger, S1
Kuster, T1
Sutter, R1
Fisch, U1
de Marcellus, C1
le Bot, S1
Decleves, X1
Baud, F1
Renolleau, S1
Oualha, M1
Dasgupta, K1
Nielson, S1
Formisano, R1
Aloisi, M1
Contrada, M1
Spanedda, F1
Schiattone, S1
Niedbala, S1
Cobianchi, MR1
Baldeschi, GC1
Buzzi, MG1
Caron, E1
Morgan, R1
Wheless, JW1
Masi, G1
Mucci, M1
Liboni, F1
Ferrari, A1
Sicca, F1
Stroud, J1
Scattoloni, J1
Blasingim, M1
Nafiu, OO1
Tyurenkov, IN1
Borodkina, LE1
Bagmetova, VV1
Berestovitskaya, VM1
Vasil'eva, OS1
Thill, C1
Di Constanzo, L1
Pessey, F1
Aries, P1
Montelescaut, É1
Sapin, J1
Vaillant, C1
Drouillard, I1
Su, W1
Yegappan, C1
Carlisle, EJ1
Clase, CM1
Clauss, RP1
Montes, MI1
Hernández Ortiz, OH1
Guerra Palacio, A1
Weißhaar, GF1
Hoemberg, M1
Bender, K1
Bangen, U1
Herkenrath, P1
Eifinger, F1
Rothschild, M1
Roth, B1
Oberthuer, A1
Martin, TW1
Mayhew, JF1
Delhaas, E1
Goslinga, S1
Chodorowski, Z2
Sein Anand, J2
Wiśniewski, M1
Burda, P1
Slaughter, AF1
Roddy, SM1
Holshouser, BA1
Abd-Allah, SA1
Tunali, Y1
Hanimoglu, H1
Tanriverdi, T1
Hanci, L1
Hanci, M1
Wall, GC1
Wasiak, A1
Hicklin, GA1
Halcomb, SE1
Holubek, WJ1
Vassallo, SU1
Brvar, M1
Vrtovec, M1
Kovac, D1
Kozelj, G1
Pezdir, T1
Bunc, M1
Abarbanel, J1
Herishanu, Y1
Byrnes, SM1
Watson, GW1
Hardy, PA1
Perry, HE1
Wright, RO1
Shannon, MW1
Woolf, AD1
Peces, R1
Navascués, RA1
Baltar, J1
Laurés, AS1
Alvarez-Grande, J1
Ostermann, ME1
Young, B1
Sibbald, WJ1
Nicolle, MW1
McDonald, NJ1
Festa, MS1
Wilkins, B1
Anderson, KJ1
Farmer, JP1
Brown, K1
Goulon, M1
Nouailhat, F1
Escourolle, R1
Zarranz-Imirizaldu, JJ1
Grosbuis, S1
Lévy-Alcover, MA1
Saissy, JM1
Demazière, J1
Vitris, M1
Seck, M1
Marcoux, L1
Gaye, M1
Ndiaye, M1
Weissenborn, K1
Wilkens, H1
Hausmann, E1
Degen, PH1
Lazorthes, Y1
Sallerin-Caute, B1
Verdie, JC1
Bastide, R1
Carillo, JP1
Müller-Schwefe, G1
Penn, RD1
Romijn, JA1
van Lieshout, JJ1
Velis, DN1
Gerkin, R1
Curry, SC1
Vance, MV1
Sankowski, PW1
Meinhart, RD1
Burris, AS1

Reviews

2 reviews available for baclofen and Coma

ArticleYear
Report of severe accidental baclofen intoxication in a healthy 4-year-old boy and review of the literature.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2019, Volume: 26, Issue:8

    Topics: Baclofen; Child, Preschool; Coma; Drug Overdose; Humans; Male; Severity of Illness Index

2019
Reduced level of consciousness from baclofen in people with low kidney function.
    BMJ (Clinical research ed.), 2009, Dec-31, Volume: 339

    Topics: Back Pain; Baclofen; Coma; Female; Humans; Kidney Failure, Chronic; Middle Aged; Muscle Relaxants, C

2009

Other Studies

41 other studies available for baclofen and Coma

ArticleYear
A Severe Baclofen Intoxication Mimicking Post-Hypoxic Encephalopathy: Wait and See!
    The Journal of emergency medicine, 2022, Volume: 62, Issue:3

    Topics: Baclofen; Brain Death; Cerebral Palsy; Coma; Humans; Hypoxia, Brain; Injections, Spinal; Male

2022
Burst Suppression Electroencephalography (EEG) Pattern with Coma and Loss of Brain Stem Reflexes Following a Baclofen Overdose with Subsequent Full Recovery.
    The American journal of case reports, 2022, Mar-31, Volume: 23

    Topics: Baclofen; Brain Stem; Coma; Drug Overdose; Electroencephalography; Female; Humans; Middle Aged

2022
On the recovery of disorders of consciousness under intrathecal baclofen administration for severe spasticity-An observational study.
    Brain and behavior, 2022, Volume: 12, Issue:5

    Topics: Baclofen; Coma; Consciousness; Humans; Injections, Spinal; Muscle Spasticity; Retrospective Studies

2022
Flumazenil partially reverses gamma-hydroxybutyrate (GHB)-induced coma: a case report.
    The American journal of drug and alcohol abuse, 2022, 09-03, Volume: 48, Issue:5

    Topics: Baclofen; Coma; Flumazenil; Humans; Sodium Oxybate

2022
Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Baclofen; Coma; Dogs; Emergency Treatment; Half-Life; Renal Dialysis

2023
Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Baclofen; Coma; Dogs; Emergency Treatment; Half-Life; Renal Dialysis

2023
Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Baclofen; Coma; Dogs; Emergency Treatment; Half-Life; Renal Dialysis

2023
Hemodialysis as emergency treatment of a severe baclofen intoxication in a 3 kg dog.
    Veterinary medicine and science, 2023, Volume: 9, Issue:1

    Topics: Animals; Baclofen; Coma; Dogs; Emergency Treatment; Half-Life; Renal Dialysis

2023
Utility of NT-proBNP monitoring in prolonged coma following massive baclofen exposure.
    Emergency medicine Australasia : EMA, 2023, Volume: 35, Issue:2

    Topics: Baclofen; Biomarkers; Coma; Heart Failure; Humans; Natriuretic Peptide, Brain; Peptide Fragments; Pr

2023
Utility of NT-proBNP monitoring in prolonged coma following massive baclofen exposure.
    Emergency medicine Australasia : EMA, 2023, Volume: 35, Issue:2

    Topics: Baclofen; Biomarkers; Coma; Heart Failure; Humans; Natriuretic Peptide, Brain; Peptide Fragments; Pr

2023
Utility of NT-proBNP monitoring in prolonged coma following massive baclofen exposure.
    Emergency medicine Australasia : EMA, 2023, Volume: 35, Issue:2

    Topics: Baclofen; Biomarkers; Coma; Heart Failure; Humans; Natriuretic Peptide, Brain; Peptide Fragments; Pr

2023
Utility of NT-proBNP monitoring in prolonged coma following massive baclofen exposure.
    Emergency medicine Australasia : EMA, 2023, Volume: 35, Issue:2

    Topics: Baclofen; Biomarkers; Coma; Heart Failure; Humans; Natriuretic Peptide, Brain; Peptide Fragments; Pr

2023
Neurological evolution of severe baclofen intoxication: from brain death mimic to recovered brain function.
    BMJ case reports, 2023, Oct-06, Volume: 16, Issue:10

    Topics: Aged; Baclofen; Brain; Brain Death; Coma; Electroencephalography; Female; Humans

2023
Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2020, Volume: 73, Issue:3

    Topics: Adult; Baclofen; Child, Preschool; Coma; Drug Overdose; Female; Humans; Muscle Relaxants, Central; R

2020
Late recovery of responsiveness after intra-thecal baclofen pump implantation and the role of diffuse pain and severe spasticity: a case report.
    Acta neurochirurgica, 2019, Volume: 161, Issue:9

    Topics: Adult; Baclofen; Coma; Decompressive Craniectomy; Hematoma; Humans; Infusion Pumps, Implantable; Inj

2019
An unusual cause of flaccid paralysis and coma: baclofen overdose.
    Journal of child neurology, 2014, Volume: 29, Issue:4

    Topics: Adolescent; Baclofen; Central Nervous System; Coma; Drug Overdose; Epilepsy, Generalized; Female; Hu

2014
Self-induced multiple comas with recreational baclofen overdoses in an adolescent girl.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:6

    Topics: Adolescent; Baclofen; Coma; Diagnostic Errors; Drug Overdose; Female; Humans; Muscle Relaxants, Cent

2013
Intrathecal baclofen toxicity: an unusual cause of paediatric postoperative coma and respiratory depression.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:6

    Topics: Adolescent; Baclofen; Cerebral Palsy; Coma; Humans; Injections, Spinal; Male; Muscle Relaxants, Cent

2014
Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid.
    Bulletin of experimental biology and medicine, 2016, Volume: 160, Issue:4

    Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Baclofen; Cinnamates; Coma; Electroshock; gam

2016
Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus.
    Annales de biologie clinique, 2016, Jun-01, Volume: 74, Issue:3

    Topics: Baclofen; Coma; Drug Overdose; Female; France; Humans; Middle Aged; Muscle Hypotonia; Self-Injurious

2016
Neurotransmitters in coma, vegetative and minimally conscious states, pharmacological interventions.
    Medical hypotheses, 2010, Volume: 75, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Baclofen; Coma; Dopamine Agents; GABA Agonists; gamma-Aminobutyric

2010
[Electroencephalographic burst-suppression pattern due to baclofen intoxication].
    Medicina intensiva, 2011, Volume: 35, Issue:9

    Topics: Baclofen; Coma; Drug Overdose; Electroencephalography; Emergencies; Fatal Outcome; Female; Humans; I

2011
Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature.
    European journal of pediatrics, 2012, Volume: 171, Issue:10

    Topics: Adolescent; Baclofen; Bradycardia; Coma; Drug Overdose; Humans; Male; Muscle Relaxants, Central; Sei

2012
Baclofen pumps: comment on Anderson et al.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:7

    Topics: Anti-Arrhythmia Agents; Atropine; Baclofen; Child; Coma; GABA Agonists; Humans; Infusion Pumps, Impl

2003
Baclofen pumps: comment on Anderson et al.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:7

    Topics: Baclofen; Child; Coma; Drug Overdose; GABA Agonists; Humans; Infusion Pumps, Implantable; Medication

2003
[Acute intoxication with baclofen].
    Przeglad lekarski, 2004, Volume: 61, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist

2004
Selected clinical aspects of acute intoxication with baclofen.
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal

2005
Magnetic resonance spectroscopy and electroencephalography in baclofen coma.
    Pediatric neurology, 2006, Volume: 34, Issue:2

    Topics: Adolescent; Baclofen; Brain; Coma; Electroencephalography; Female; Humans; Magnetic Resonance Spectr

2006
Intrathecal baclofen toxicity and deep coma in minutes.
    The journal of spinal cord medicine, 2006, Volume: 29, Issue:3

    Topics: Adult; Baclofen; Coma; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Muscle Spasticit

2006
An initially unsuspected case of baclofen overdose.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2006, Volume: 15, Issue:6

    Topics: Baclofen; Coma; Drug Overdose; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Muscle Relaxants,

2006
The clinical approach to coma.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2006, Volume: 13, Issue:6

    Topics: Aged; Baclofen; Coma; Diagnosis, Differential; Emergency Treatment; Humans; Male; Medical History Ta

2006
Haemodialysis clearance of baclofen.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:12

    Topics: Acute Kidney Injury; Area Under Curve; Baclofen; Coma; Drug Overdose; GABA Agonists; Humans; Male; M

2007
[Periodic triphasic EEG waves].
    Harefuah, 1982, Nov-15, Volume: 103, Issue:10

    Topics: Baclofen; Brain Diseases; Coma; Electroencephalography; Humans; Hypernatremia; Periodicity; Phenothi

1982
Flumazenil: an unreliable antagonist in baclofen overdose.
    Anaesthesia, 1996, Volume: 51, Issue:5

    Topics: Adult; Antidotes; Baclofen; Coma; Female; Flumazenil; GABA Modulators; Humans; Muscle Relaxants, Cen

1996
Baclofen overdose: drug experimentation in a group of adolescents.
    Pediatrics, 1998, Volume: 101, Issue:6

    Topics: Adolescent; Apnea; Baclofen; Coma; Drug Overdose; Female; GABA Agonists; Humans; Male; Muscle Relaxa

1998
Baclofen neurotoxicity in chronic haemodialysis patients with hiccups.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:7

    Topics: Aged; Baclofen; Central Nervous System; Coma; Confusion; GABA Agonists; Hiccup; Humans; Kidney Failu

1998
Coma mimicking brain death following baclofen overdose.
    Intensive care medicine, 2000, Volume: 26, Issue:8

    Topics: Baclofen; Brain Death; Coma; Diagnosis, Differential; Drug Overdose; Humans; Male; Middle Aged; Musc

2000
Teenage coma.
    Journal of paediatrics and child health, 2001, Volume: 37, Issue:4

    Topics: Adolescent; Baclofen; Coma; Drug Overdose; Humans; Male; Muscle Relaxants, Central

2001
Reversible coma in children after improper baclofen pump insertion.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:5

    Topics: Analgesics, Opioid; Baclofen; Cerebral Palsy; Child; Child, Preschool; Coma; Female; GABA Agonists;

2002
[Methyl bromide poisoning. 3 cases, 1 fatal. Neruopathological study of one case of coma with myoclonus followed for 5 years].
    Revue neurologique, 1975, Volume: 131, Issue:7

    Topics: Adolescent; Adult; Baclofen; Cerebellum; Cerebral Cortex; Chlormethiazole; Clonazepam; Coma; Cortica

1975
Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation.
    Intensive care medicine, 1992, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Africa; Age Factors; Aged; Baclofen; Blood Gas Analysis; Coma; Creatine Kinase; D

1992
Burst suppression EEG with baclofen overdose.
    Clinical neurology and neurosurgery, 1991, Volume: 93, Issue:1

    Topics: Adult; Baclofen; Coma; Drug Overdose; Electroencephalography; Female; Humans; Suicide, Attempted

1991
Chronic intrathecal baclofen administration for control of severe spasticity.
    Journal of neurosurgery, 1990, Volume: 72, Issue:3

    Topics: Baclofen; Coma; Drug Overdose; Drug Tolerance; Evaluation Studies as Topic; Humans; Infusion Pumps,

1990
Physostigmine in the treatment of intrathecal baclofen overdose. Report of three cases.
    Journal of neurosurgery, 1989, Volume: 71, Issue:2

    Topics: Adult; Baclofen; Coma; Humans; Injections, Spinal; Male; Middle Aged; Physostigmine; Respiratory Ins

1989
Reversible coma due to intrathecal baclofen.
    Lancet (London, England), 1986, Sep-20, Volume: 2, Issue:8508

    Topics: Adult; Baclofen; Coma; Humans; Injections, Spinal; Male; Tetanus; Trismus

1986
First-order elimination kinetics following baclofen overdose.
    Annals of emergency medicine, 1986, Volume: 15, Issue:7

    Topics: Baclofen; Cardiovascular Diseases; Coma; Female; Half-Life; Humans; Kinetics; Middle Aged; Seizures;

1986
Overdose with baclofen.
    Southern medical journal, 1986, Volume: 79, Issue:1

    Topics: Adult; Baclofen; Coma; Female; Gastric Lavage; Humans; Seizures

1986