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baclofen and Cognition Disorders

baclofen has been researched along with Cognition Disorders in 16 studies

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"In trials to preserve the pharmacological profile and improve the bioavailability via lipophilicity increment of baclofen 1 and searching for more potent and less toxic muscle relaxants and analgesics, nine substituted cyclic analogues of 1 were designed and synthesized."1.355-(4-Chlorophenyl)-5,6-dihydro-1,3-oxazepin-7(4H)-one derivatives as lipophilic cyclic analogues of baclofen: design, synthesis, and neuropharmacological evaluation. ( Abdel-Hafez, AA; Abdel-Wahab, BA, 2008)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Abdel-Hafez, AA1
Abdel-Wahab, BA1
Axelsson, SFA1
Horst, NK1
Horiguchi, N1
Roberts, AC1
Robbins, TW1
Stoppel, LJ1
Kazdoba, TM1
Schaffler, MD1
Preza, AR1
Heynen, A1
Crawley, JN1
Bear, MF1
Weerts, AP1
Pattyn, N1
Van de Heyning, PH1
Wuyts, FL1
Lu, Y1
Li, CJ1
Chen, C1
Luo, P1
Zhou, M1
Li, C1
Xu, XL1
Lu, Q1
He, Z1
Guo, LJ1
Arai, S1
Takuma, K1
Mizoguchi, H1
Ibi, D1
Nagai, T1
Kamei, H1
Kim, HC1
Yamada, K1
Fejgin, K1
Pålsson, E1
Wass, C1
Finnerty, N1
Lowry, J1
Klamer, D1
Pangilinan, PH1
Giacoletti-Argento, A1
Shellhaas, R1
Hurvitz, EA1
Hornyak, JE1
Nomura, S1
Kagawa, Y1
Kida, H1
Maruta, Y1
Imoto, H1
Fujii, M1
Suzuki, M1
Porrino, LJ1
Hampson, RE1
Opris, I1
Deadwyler, SA1
Marshall, FH1
Ling, W2
Rawson, R1
Shoptaw, S1
Stevenson, VL1
Pirovino, M1
Meier, J1
Meyer, M1
Waldmeier, P1
Schmid, M1
Calvet, D1
Touzé, E1
Delegue, P1
Bertherat, J1
Zuber, M1
White, WB1

Reviews

4 reviews available for baclofen and Cognition Disorders

ArticleYear
Neuropharmacology in pediatric brain injury: a review.
    PM & R : the journal of injury, function, and rehabilitation, 2010, Volume: 2, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Anticonvulsants; Antidepressive Agents; Antipsychotic Agent

2010
Is the GABA B heterodimer a good drug target?
    Journal of molecular neuroscience : MN, 2005, Volume: 26, Issue:2-3

    Topics: Animals; Baclofen; Brain; Cognition Disorders; Depression; Dimerization; GABA Agonists; GABA Antagon

2005
Management of methamphetamine abuse and dependence.
    Current psychiatry reports, 2006, Volume: 8, Issue:5

    Topics: Baclofen; Benzhydryl Compounds; Brain; Bupropion; Cognition Disorders; Cognitive Behavioral Therapy;

2006
Relief of symptoms in end-stage neurological conditions.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:12

    Topics: Baclofen; Clinical Trials, Phase I as Topic; Cognition Disorders; Deglutition Disorders; Humans; Moo

2007

Trials

1 trial available for baclofen and Cognition Disorders

ArticleYear
Evaluation of the effects of anti-motion sickness drugs on subjective sleepiness and cognitive performance of healthy males.
    Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:7

    Topics: Adult; Antiemetics; Baclofen; Cinnarizine; Cognition; Cognition Disorders; Dimenhydrinate; Double-Bl

2014

Other Studies

11 other studies available for baclofen and Cognition Disorders

ArticleYear
5-(4-Chlorophenyl)-5,6-dihydro-1,3-oxazepin-7(4H)-one derivatives as lipophilic cyclic analogues of baclofen: design, synthesis, and neuropharmacological evaluation.
    Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17

    Topics: Animals; Baclofen; Cognition Disorders; Cyclization; Dose-Response Relationship, Drug; Drug Design;

2008
Flexible versus Fixed Spatial Self-Ordered Response Sequencing: Effects of Inactivation and Neurochemical Modulation of Ventrolateral Prefrontal Cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021, 08-25, Volume: 41, Issue:34

    Topics: Animals; Antipsychotic Agents; Baclofen; Callithrix; Cognition Disorders; Dopamine; Dopamine D2 Rece

2021
R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:3

    Topics: Animals; Autistic Disorder; Baclofen; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human,

2018
Activation of GABAB2 subunits alleviates chronic cerebral hypoperfusion-induced anxiety-like behaviours: A role for BDNF signalling and Kir3 channels.
    Neuropharmacology, 2016, Volume: 110, Issue:Pt A

    Topics: Animals; Anxiety; Baclofen; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Carotid Arte

2016
GABAB receptor agonist baclofen improves methamphetamine-induced cognitive deficit in mice.
    European journal of pharmacology, 2009, Jan-05, Volume: 602, Issue:1

    Topics: Animals; Baclofen; Cognition Disorders; Dose-Response Relationship, Drug; GABA Agonists; Male; Memor

2009
Prefrontal GABA(B) receptor activation attenuates phencyclidine-induced impairments of prepulse inhibition: involvement of nitric oxide.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:7

    Topics: Acoustic Stimulation; Animals; Baclofen; Cognition Disorders; Disease Models, Animal; Dose-Response

2009
Effects of intrathecal baclofen therapy on motor and cognitive functions in a rat model of cerebral palsy.
    Journal of neurosurgery. Pediatrics, 2012, Volume: 9, Issue:2

    Topics: Animals; Animals, Newborn; Baclofen; Cerebral Palsy; Cognition Disorders; Electric Stimulation; Evok

2012
Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen.
    Psychopharmacology, 2013, Volume: 225, Issue:1

    Topics: Animals; Baclofen; Brain; Cocaine; Cognition; Cognition Disorders; Dose-Response Relationship, Drug;

2013
[Malignant neuroleptics syndrome].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-09, Volume: 109, Issue:10

    Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal

1984
[Stiff limb syndrome associated with Hashimoto's encephalopathy: improvement after corticotherapy].
    Revue neurologique, 2002, Volume: 158, Issue:5 Pt 1

    Topics: Aged; Antibody Specificity; Anticonvulsants; Antithyroid Agents; Autoantibodies; Autoimmune Diseases

2002
Aggravated CNS depression with urinary retention secondary to baclofen administration.
    Archives of internal medicine, 1985, Volume: 145, Issue:9

    Topics: Aged; Baclofen; Cognition Disorders; Female; Humans; Substance Withdrawal Syndrome; Urination Disord

1985