baclofen has been researched along with Chronic Hepatitis C in 2 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral baclofen was given at dosages of 0 (placebo) or 30 mg/day over 12 weeks with concomitant manual-guided counseling." | 6.84 | The safety and efficacy of baclofen to reduce alcohol use in veterans with chronic hepatitis C: a randomized controlled trial. ( Dieperink, E; Fuller, B; Hauser, P; Ho, SB; Kern, S; Thuras, P, 2017) |
| "Oral baclofen was given at dosages of 0 (placebo) or 30 mg/day over 12 weeks with concomitant manual-guided counseling." | 2.84 | The safety and efficacy of baclofen to reduce alcohol use in veterans with chronic hepatitis C: a randomized controlled trial. ( Dieperink, E; Fuller, B; Hauser, P; Ho, SB; Kern, S; Thuras, P, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hauser, P | 1 |
| Fuller, B | 1 |
| Ho, SB | 1 |
| Thuras, P | 1 |
| Kern, S | 1 |
| Dieperink, E | 1 |
| Leggio, L | 1 |
| Ferrulli, A | 1 |
| Zambon, A | 1 |
| Caputo, F | 1 |
| Kenna, GA | 1 |
| Swift, RM | 1 |
| Addolorato, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind, Placebo-Controlled, Randomized Human Laboratory Pilot Study of Baclofen in Anxious Alcoholics[NCT01751386] | Phase 2 | 39 participants (Actual) | Interventional | 2012-12-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Amount of alcohol was measured as the number of mini-drinks each participant decided to drink (0-8 mini-drinks). The alcohol content of each mini-drink was calculated based on the participants' total body water, and was designed to raise the blood alcohol concentration by 0.015 g/dL. (NCT01751386)
Timeframe: 2 hours
| Intervention | mini-drinks (Mean) |
|---|---|
| Baclofen | 4.11 |
| Placebo | 4.5 |
2 trials available for baclofen and Chronic Hepatitis C
| Article | Year |
|---|---|
The safety and efficacy of baclofen to reduce alcohol use in veterans with chronic hepatitis C: a randomized controlled trial.
Topics: Alcoholism; Baclofen; Double-Blind Method; Female; Follow-Up Studies; GABA-B Receptor Agonists; Hepa | 2017 |
Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection.
Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Female; GABA-B Receptor Agonists; | 2012 |