baclofen has been researched along with Chronic Disease in 61 studies
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough." | 9.30 | Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019) |
| "To substantiate a previously reported disturbance of gamma-aminobutyric acid (GABA) in chronic schizophrenia, plasma growth hormone (GH) response to a direct GABA agonist (baclofen, 10 mg) was assessed in 12 unmedicated chronic schizophrenic males and 10 sex- and age-matched healthy controls." | 9.06 | Baclofen-induced growth hormone secretion is blunted in chronic schizophrenics: neuroendocrine evidence for a GABA disturbance in schizophrenia. ( Forziati, D; Iovino, M; Maj, M; Monteleone, P; Steardo, L; Veltro, F, 1988) |
| "A double-blind trial with two parallel groups was carried out to compare the antispastic effect and tolerability of a new muscle relaxant, tizanidine (DS 103-282), with those of baclofen in the treatment of spasticity due to multiple sclerosis." | 9.05 | A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis. ( Muff, S; Smolenski, C; Smolenski-Kautz, S, 1981) |
| "Therapeutic efficacy of baclofen is suboptimal in the treatment of refractory gastroesophageal reflux-induced chronic cough (GERC)." | 8.02 | Pressure and length of the lower esophageal sphincter as predictive indicators of therapeutic efficacy of baclofen for refractory gastroesophageal reflux-induced chronic cough. ( Qiu, Z; Si, F; Sun, H; Xu, X; Yu, L; Zhang, M; Zhu, Y, 2021) |
| "Ischemic paraplegia was induced in Sprague-Dawley rats by transient aortic occlusion (10 min) in combination with systemic hypotension (40 mm Hg)." | 5.33 | Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter. ( Hefferan, MP; Kakinohana, O; Marsala, J; Marsala, M; Nakamura, S; Tomori, Z, 2005) |
| "To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal reflux-induced chronic cough." | 5.30 | Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough. ( Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M, 2019) |
| "Atypical facial pain is a clinical syndrome of facial pain that has been related to depression but whose pathogenesis is not known." | 5.28 | Atypical facial pain, ectasia of the basilar artery, and baclofen: a case report. ( Ferro, JM; Martins, IP, 1989) |
| "This study assessed the safety and efficacy of intrathecal baclofen in the treatment of intractable spasticity caused by spinal cord injury or multiple sclerosis." | 5.07 | Intrathecal baclofen for treatment of intractable spinal spasticity. ( Abel, NA; Smith, RA, 1994) |
| "To substantiate a previously reported disturbance of gamma-aminobutyric acid (GABA) in chronic schizophrenia, plasma growth hormone (GH) response to a direct GABA agonist (baclofen, 10 mg) was assessed in 12 unmedicated chronic schizophrenic males and 10 sex- and age-matched healthy controls." | 5.06 | Baclofen-induced growth hormone secretion is blunted in chronic schizophrenics: neuroendocrine evidence for a GABA disturbance in schizophrenia. ( Forziati, D; Iovino, M; Maj, M; Monteleone, P; Steardo, L; Veltro, F, 1988) |
| "A double-blind trial with two parallel groups was carried out to compare the antispastic effect and tolerability of a new muscle relaxant, tizanidine (DS 103-282), with those of baclofen in the treatment of spasticity due to multiple sclerosis." | 5.05 | A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis. ( Muff, S; Smolenski, C; Smolenski-Kautz, S, 1981) |
| "The goal of this systematic review was to examine the evidence for the use of the neuromodulating agents, amitriptyline, gabapentin, pregabalin, and baclofen, in the management of chronic, idiopathic cough patients." | 4.89 | Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review. ( Cohen, SM; Misono, S, 2013) |
| " To date, only the antidepressants and the anticonvulsants have shown any effectiveness, albeit incomplete and inconsistent, and many questions remain unanswered: What are the exact indications for the antidepressants? What component of neuropathic pain do they relieve, and through which mechanisms? Which type of antidepressants should be prescribed? A first-generation tricyclic? Or a new compound with a selective action on serotonin reuptake? What are the effective dosage and duration of the treatment? What is it mechanism of action? What other antalgic effects do carbamazepine and baclofen possess apart from their action on trigeminal neuralgia? The opiates are generally considered to be without effect, but recent clinical and experimental findings seem to point otherwise." | 4.78 | [Pharmacological treatment of neuropathic pain]. ( Ollat, H, 1992) |
| "Therapeutic efficacy of baclofen is suboptimal in the treatment of refractory gastroesophageal reflux-induced chronic cough (GERC)." | 4.02 | Pressure and length of the lower esophageal sphincter as predictive indicators of therapeutic efficacy of baclofen for refractory gastroesophageal reflux-induced chronic cough. ( Qiu, Z; Si, F; Sun, H; Xu, X; Yu, L; Zhang, M; Zhu, Y, 2021) |
| "Non-acid GERC had the similar cough character, cough symptom score, and capsaicin cough sensitivity to acid GERC." | 3.81 | Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux. ( Chen, Q; Liang, S; Lü, H; Qiu, Z; Xu, X; Yang, Z; Yu, L, 2015) |
| "Baclofen daily dose was 30 mg to 300 mg: 10 RCTs used low doses (30 mg or less); eight RCTs medium doses (above 30 and 100 mg or less) and four RCTs high doses (above 100 mg)." | 3.01 | Baclofen for alcohol use disorder. ( Agabio, R; Minozzi, S; Rösner, S; Saulle, R, 2023) |
| "Baclofen was not effective at sustaining plasma IGF-1 concentrations in the physiological range in men with chronic SCI." | 2.78 | Low-dose baclofen therapy raised plasma insulin-like growth factor-1 concentrations, but not into the normal range in a predictable and sustained manner in men with chronic spinal cord injury. ( Bauman, WA; Cirnigliaro, CM; Kirshblum, SC; La Fountaine, MF; Spungen, AM, 2013) |
| "Baclofen therapy was well tolerated, as only 1 patient dropped out due to adverse effects." | 2.71 | Baclofen treatment for chronic posttraumatic stress disorder. ( Ambrose, SM; Cates, ME; Davis, LL; Drake, RG; Jewell, ME; Lowe, JS, 2003) |
| "In up to 30% of patients with typical GERD symptoms (heartburn and/or regurgitation), acid-suppressive therapy does not provide clinical benefit." | 2.53 | Management of refractory typical GERD symptoms. ( Ang, D; De Santis, A; Pauwels, A; Scarpellini, E; Tack, J; Vanuytsel, T, 2016) |
| "Chronic cough is a common symptom that can be difficult to treat." | 2.52 | NMDA and GABA receptors as potential targets in cough hypersensitivity syndrome. ( Chung, KF, 2015) |
| "Why is it important to treat spastic patients and what treatment does one use? When should one consider a change in the strategy and why is it necessary to have a clear discharge policy from the service to avoid serious logistic problems? The review reiterates the role of physical treatment in the management and thereafter the maintenance of patients with spasticity." | 2.42 | Long-term modification of spasticity. ( Ward, AB, 2003) |
| "Trigeminal neuralgia is probably the most excruciatingly painful disorder to afflict mankind and is refractory to all conventional analgesic agents." | 2.38 | Trigeminal neuralgia and related disorders. ( Fromm, GH, 1989) |
| "Treatment of Alzheimer's disease is currently being investigated using intraventricular bethanechol." | 2.37 | Drug pumps for treatment of neurologic diseases and pain. ( Penn, RD, 1985) |
| "Tinnitus is the perception of phantom sounds, a phenomenon believed to be due to abnormal neuronal activity in auditory regions of the CNS such as the brainstem cochlear nucleus (CN)." | 1.42 | Glutamic acid decarboxylase levels in the cochlear nucleus of rats with acoustic trauma-induced chronic tinnitus. ( Dixon, S; MacPherson, K; McPherson, K; Smith, PF; Zheng, Y, 2015) |
| "Baclofen treatment affected the impact of chronic stress on different phases of morphine-induced CPP." | 1.40 | Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice. ( Meng, S; Qi, X; Quan, W; Su, Z; Yang, S, 2014) |
| "Baclofen is a GABA(B) receptor agonist." | 1.39 | Baclofen in the treatment of persistent hiccup: a case series. ( Addolorato, G; Antonelli, M; D'Angelo, C; Ferrulli, A; Landolfi, R; Leggio, L; Mirijello, A; Vassallo, G, 2013) |
| "In one patient, the BS along with spastic signs disappeared after intrathecal injection of Baclofen." | 1.36 | The occurrence of the Babinski sign in complete spinal cord injury. ( Dietz, V; Petersen, JA; Schubert, M, 2010) |
| "Ischemic paraplegia was induced in Sprague-Dawley rats by transient aortic occlusion (10 min) in combination with systemic hypotension (40 mm Hg)." | 1.33 | Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter. ( Hefferan, MP; Kakinohana, O; Marsala, J; Marsala, M; Nakamura, S; Tomori, Z, 2005) |
| "baclofen treatment also decreased, where after 5 days of baclofen infusion 1." | 1.33 | Development of baclofen tolerance in a rat model of chronic spasticity and rigidity. ( Fuchigami, T; Hefferan, MP; Marsala, M, 2006) |
| "Patients that were receiving anti-spasticity medications (e." | 1.32 | Windup of flexion reflexes in chronic human spinal cord injury: a marker for neuronal plateau potentials? ( Benz, EN; Hornby, TG; Rymer, WZ; Schmit, BD, 2003) |
| "Baclofen has both presynaptic and postsynaptic effects." | 1.31 | gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension. ( Mifflin, SW; Vitela, M, 2001) |
| "Baclofen was used as a first treatment in patients without evidence of any gastro-oesophageal disease (n = 17), and was undertaken only after full treatment of such disease (n = 55) had failed to solve the hiccup problem (n = 20)." | 1.29 | Baclofen therapy for chronic hiccup. ( Bizec, JL; Cabane, J; Derenne, JP; Guelaud, C; Similowski, T; Whitelaw, WA, 1995) |
| "Atypical facial pain is a clinical syndrome of facial pain that has been related to depression but whose pathogenesis is not known." | 1.28 | Atypical facial pain, ectasia of the basilar artery, and baclofen: a case report. ( Ferro, JM; Martins, IP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (21.31) | 18.7374 |
| 1990's | 12 (19.67) | 18.2507 |
| 2000's | 19 (31.15) | 29.6817 |
| 2010's | 14 (22.95) | 24.3611 |
| 2020's | 3 (4.92) | 2.80 |
| Authors | Studies |
|---|---|
| Agabio, R | 1 |
| Saulle, R | 1 |
| Rösner, S | 1 |
| Minozzi, S | 1 |
| Grech, E | 1 |
| Attard, SC | 1 |
| Attard, A | 1 |
| Farrugia, E | 1 |
| Zhu, Y | 1 |
| Xu, X | 3 |
| Zhang, M | 2 |
| Si, F | 1 |
| Sun, H | 1 |
| Yu, L | 3 |
| Qiu, Z | 3 |
| Kohse, EK | 1 |
| Hollmann, MW | 1 |
| Bardenheuer, HJ | 1 |
| Kessler, J | 1 |
| Dong, R | 1 |
| Ding, H | 1 |
| Pan, J | 1 |
| Yu, Y | 1 |
| Shi, C | 1 |
| Chen, Q | 2 |
| Lv, H | 1 |
| Mirijello, A | 1 |
| Addolorato, G | 1 |
| D'Angelo, C | 1 |
| Ferrulli, A | 1 |
| Vassallo, G | 1 |
| Antonelli, M | 1 |
| Leggio, L | 1 |
| Landolfi, R | 1 |
| Meng, S | 1 |
| Quan, W | 1 |
| Qi, X | 1 |
| Su, Z | 1 |
| Yang, S | 1 |
| Bauman, WA | 2 |
| La Fountaine, MF | 1 |
| Cirnigliaro, CM | 2 |
| Kirshblum, SC | 2 |
| Spungen, AM | 2 |
| Yang, Z | 1 |
| Liang, S | 1 |
| Lü, H | 1 |
| Zheng, Y | 1 |
| Dixon, S | 1 |
| McPherson, K | 1 |
| MacPherson, K | 1 |
| Smith, PF | 1 |
| Chung, KF | 1 |
| Scarpellini, E | 1 |
| Ang, D | 1 |
| Pauwels, A | 1 |
| De Santis, A | 1 |
| Vanuytsel, T | 1 |
| Tack, J | 1 |
| Landry, M | 1 |
| Nagy, F | 1 |
| Wang, RJ | 1 |
| Zeng, QH | 1 |
| Wang, WZ | 1 |
| Wang, W | 1 |
| Petersen, JA | 1 |
| Schubert, M | 1 |
| Dietz, V | 1 |
| Thomas, CK | 1 |
| Häger-Ross, CK | 1 |
| Klein, CS | 1 |
| Zhang, W | 2 |
| Mifflin, S | 2 |
| Johnson, BA | 1 |
| Cohen, SM | 1 |
| Misono, S | 1 |
| Hornby, TG | 1 |
| Rymer, WZ | 1 |
| Benz, EN | 1 |
| Schmit, BD | 1 |
| Ward, AB | 1 |
| Drake, RG | 1 |
| Davis, LL | 1 |
| Cates, ME | 1 |
| Jewell, ME | 1 |
| Ambrose, SM | 1 |
| Lowe, JS | 1 |
| Plassat, R | 1 |
| Perrouin Verbe, B | 1 |
| Menei, P | 1 |
| Menegalli, D | 1 |
| Mathé, JF | 1 |
| Richard, I | 1 |
| Li, Y | 1 |
| Li, X | 1 |
| Harvey, PJ | 1 |
| Bennett, DJ | 1 |
| Marsala, M | 2 |
| Hefferan, MP | 2 |
| Kakinohana, O | 1 |
| Nakamura, S | 1 |
| Marsala, J | 1 |
| Tomori, Z | 1 |
| Potes, CS | 2 |
| Neto, FL | 2 |
| Castro-Lopes, JM | 2 |
| Morrison, NG | 1 |
| Zhang, RL | 1 |
| Fuchigami, T | 1 |
| Herrera-Rosales, M | 1 |
| Nayak, S | 1 |
| Roberts, S | 1 |
| Cunliffe, M | 1 |
| Wolf, ME | 1 |
| Keener, S | 1 |
| Mathis, P | 1 |
| Mosnaim, AD | 1 |
| Nair, NP | 1 |
| Lal, S | 1 |
| Schwartz, G | 1 |
| Thavundayil, JX | 1 |
| Smolenski, C | 1 |
| Muff, S | 1 |
| Smolenski-Kautz, S | 1 |
| Guelaud, C | 1 |
| Similowski, T | 2 |
| Bizec, JL | 2 |
| Cabane, J | 2 |
| Whitelaw, WA | 1 |
| Derenne, JP | 2 |
| Watts, AE | 1 |
| Whittington, MA | 1 |
| Jefferys, JG | 1 |
| Abel, NA | 1 |
| Smith, RA | 1 |
| Dicpinigaitis, PV | 1 |
| Rauf, K | 1 |
| Walker, P | 1 |
| Watanabe, S | 1 |
| Bruera, E | 1 |
| Petroianu, G | 2 |
| Hein, G | 2 |
| Petroianu, A | 1 |
| Bergler, W | 2 |
| Rüfer, R | 2 |
| Ansó Oliván, S | 1 |
| Alvarez Martín, T | 1 |
| Merino Arribas, JM | 1 |
| Sanchez Martín, J | 1 |
| Carpintero Martín, I | 1 |
| González de la Rosa, JB | 1 |
| Oneschuk, D | 1 |
| Zuniga, RE | 1 |
| Schlicht, CR | 1 |
| Abram, SE | 1 |
| Santos, Tde J | 1 |
| de Castro-Costa, CM | 1 |
| Giffoni, SD | 1 |
| Santos, FJ | 1 |
| Ramos, RS | 1 |
| Gifoni, MA | 1 |
| Stegmeier-Petroianu, A | 1 |
| Choo, YM | 1 |
| Kim, GB | 1 |
| Choi, JY | 1 |
| Park, JH | 2 |
| Yang, CW | 1 |
| Kim, YS | 1 |
| Bang, BK | 1 |
| Vitela, M | 1 |
| Mifflin, SW | 1 |
| Boz, C | 1 |
| Velioglu, S | 1 |
| Bulbul, I | 1 |
| Ozmenoglu, M | 1 |
| Bigelow, LB | 2 |
| Nasrallah, H | 1 |
| Carman, J | 1 |
| Gillin, JC | 1 |
| Wyatt, RJ | 1 |
| Beckmann, H | 1 |
| Frische, M | 1 |
| Rüther, E | 1 |
| Zimmer, R | 1 |
| Schöpf, J | 1 |
| Hucker, H | 1 |
| Ollat, H | 1 |
| Desmet, V | 1 |
| Launois, S | 1 |
| Orcel, B | 1 |
| Silbert, PL | 1 |
| Stewart-Wynne, EG | 1 |
| Saltuari, L | 1 |
| Schmutzhard, E | 1 |
| Kofler, M | 1 |
| Baumgartner, H | 1 |
| Aichner, F | 1 |
| Gerstenbrand, F | 1 |
| Yaqoob, M | 1 |
| Prabhu, P | 1 |
| Ahmad, R | 1 |
| Martins, IP | 1 |
| Ferro, JM | 1 |
| Fromm, GH | 1 |
| Monteleone, P | 1 |
| Maj, M | 1 |
| Iovino, M | 1 |
| Forziati, D | 1 |
| Veltro, F | 1 |
| Steardo, L | 1 |
| Penn, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined Scalp and Ear Acupuncture in Patients With Proton Pump Inhibitor- Dependent Gastroesophageal Reflux Disease[NCT04660019] | 43 participants (Actual) | Interventional | 2020-08-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for baclofen and Chronic Disease
| Article | Year |
|---|---|
Baclofen for alcohol use disorder.
Topics: Acamprosate; Adult; Alcohol Drinking; Alcoholism; Baclofen; Chronic Disease; Female; Humans; Male; M | 2023 |
Chronic Hiccups: An Underestimated Problem.
Topics: Amines; Anesthesiology; Baclofen; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Am | 2017 |
NMDA and GABA receptors as potential targets in cough hypersensitivity syndrome.
Topics: Animals; Antitussive Agents; Baclofen; Chronic Disease; Cough; GABA-B Receptor Agonists; Humans; Hyp | 2015 |
Management of refractory typical GERD symptoms.
Topics: Alginates; Algorithms; Antacids; Baclofen; Chronic Disease; Esophagoscopy; Gastroesophageal Reflux; | 2016 |
[GABA(B) receptors and sensitization to pain].
Topics: 14-3-3 Proteins; Allosteric Regulation; Animals; Baclofen; Calcium Channels; Calcium-Binding Protein | 2009 |
Medication treatment of different types of alcoholism.
Topics: Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Chronic Disease; Depressive Disorder; Female; | 2010 |
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; ga | 2013 |
Long-term modification of spasticity.
Topics: Algorithms; Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Chronic Disease; Denervation; Humans | 2003 |
[Pharmacological treatment of neuropathic pain].
Topics: Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Baclofen; Capsaicin; Chronic Disease; Di | 1992 |
Trigeminal neuralgia and related disorders.
Topics: Baclofen; Carbamazepine; Chronic Disease; Humans; Trigeminal Neuralgia | 1989 |
Drug pumps for treatment of neurologic diseases and pain.
Topics: Alzheimer Disease; Baclofen; Bethanechol; Bethanechol Compounds; Catheters, Indwelling; Chronic Dise | 1985 |
14 trials available for baclofen and Chronic Disease
| Article | Year |
|---|---|
Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough.
Topics: Adult; Analgesics; Baclofen; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Follo | 2019 |
Low-dose baclofen therapy raised plasma insulin-like growth factor-1 concentrations, but not into the normal range in a predictable and sustained manner in men with chronic spinal cord injury.
Topics: Adult; Baclofen; Chronic Disease; Dose-Response Relationship, Drug; Humans; Insulin-Like Growth Fact | 2013 |
Baclofen treatment for chronic posttraumatic stress disorder.
Topics: Adult; Aged; Baclofen; Chronic Disease; Combat Disorders; GABA-B Receptor Agonists; Humans; Male; Mi | 2003 |
Effect of low-dose baclofen administration on plasma insulin-like growth factor-I in persons with spinal cord injury.
Topics: Adult; Baclofen; Chronic Disease; Dose-Response Relationship, Drug; Humans; Insulin-Like Growth Fact | 2006 |
A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.
Topics: Adult; Aged; Baclofen; Chronic Disease; Clinical Trials as Topic; Clonidine; Double-Blind Method; Fe | 1981 |
Intrathecal baclofen for treatment of intractable spinal spasticity.
Topics: Adult; Baclofen; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hum | 1994 |
Treatment of chronic, refractory cough with baclofen.
Topics: Administration, Oral; Adult; Aged; Baclofen; Bronchial Provocation Tests; Capsaicin; Chronic Disease | 1998 |
Intrathecal baclofen is analgesic in patients with chronic pain.
Topics: Aged; Amputation, Surgical; Baclofen; Cerebral Palsy; Chronic Disease; Female; GABA Agonists; Hemato | 2000 |
Baclofen is effective in intractable hiccups induced by brainstem lesions.
Topics: Adult; Aged; Baclofen; Brain Stem; Brain Stem Infarctions; Chronic Disease; GABA Agonists; gamma-Ami | 2001 |
Baclofen in chronic schizophrenia.
Topics: Adult; Aminobutyrates; Baclofen; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Sc | 1977 |
Baclofen treatment in chronic schizophrenia: a clinical trial.
Topics: Adult; Aminobutyrates; Arousal; Baclofen; Chronic Disease; Clinical Trials as Topic; Depression; Dru | 1977 |
Baclofen (para-chlorphenyl-GABA) in schizophrenia.
Topics: Adult; Aminobutyrates; Animals; Baclofen; Blood-Brain Barrier; Chronic Disease; Clinical Trials as T | 1977 |
Baclofen in the treatment of schizophrenia: a pilot study.
Topics: Adult; Aminobutyrates; Baclofen; Chronic Disease; Clinical Trials as Topic; Female; Humans; Middle A | 1977 |
Baclofen-induced growth hormone secretion is blunted in chronic schizophrenics: neuroendocrine evidence for a GABA disturbance in schizophrenia.
Topics: Adult; Aged; Baclofen; Brain; Chronic Disease; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male | 1988 |
36 other studies available for baclofen and Chronic Disease
| Article | Year |
|---|---|
Baclofen toxicity in a patient with advanced chronic kidney disease.
Topics: Baclofen; Chronic Disease; Humans; Kidney Failure, Chronic; Renal Insufficiency, Chronic | 2023 |
Pressure and length of the lower esophageal sphincter as predictive indicators of therapeutic efficacy of baclofen for refractory gastroesophageal reflux-induced chronic cough.
Topics: Baclofen; Chronic Disease; Cough; Esophageal Sphincter, Lower; Female; Gastroesophageal Reflux; Huma | 2021 |
Baclofen in the treatment of persistent hiccup: a case series.
Topics: Aged; Baclofen; Chronic Disease; Female; GABA-B Receptor Agonists; Hiccup; Humans; Male; Middle Aged | 2013 |
Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice.
Topics: Analysis of Variance; Animals; Baclofen; Chronic Disease; Conditioning, Operant; Dose-Response Relat | 2014 |
Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux.
Topics: Adult; Anti-Ulcer Agents; Baclofen; Capsaicin; Chronic Disease; Cough; Domperidone; Esophageal pH Mo | 2015 |
Glutamic acid decarboxylase levels in the cochlear nucleus of rats with acoustic trauma-induced chronic tinnitus.
Topics: Animals; Baclofen; Chronic Disease; Cochlear Nucleus; GABA-B Receptor Agonists; Glutamate Decarboxyl | 2015 |
GABA(A) and GABA(B) receptor-mediated inhibition of sympathetic outflow in the paraventricular nucleus is blunted in chronic heart failure.
Topics: Adrenergic Fibers; Animals; Baclofen; Bicuculline; Blood Pressure; Chronic Disease; GABA Agonists; G | 2009 |
The occurrence of the Babinski sign in complete spinal cord injury.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Chronic Disease; Female; Humans; Male; Middle Aged; Muscle | 2010 |
Effects of baclofen on motor units paralysed by chronic cervical spinal cord injury.
Topics: Adult; Baclofen; Cervical Vertebrae; Chronic Disease; Electric Stimulation; Female; Humans; Male; Mi | 2010 |
Chronic hypertension enhances presynaptic inhibition by baclofen in the nucleus of the solitary tract.
Topics: Animals; Baclofen; Baroreflex; Chronic Disease; Disease Models, Animal; GABA Agonists; Glutamic Acid | 2010 |
Windup of flexion reflexes in chronic human spinal cord injury: a marker for neuronal plateau potentials?
Topics: Adult; Aged; Baclofen; Chronic Disease; Electric Stimulation; Electromyography; Female; Humans; Inte | 2003 |
Treatment of spasticity with intrathecal Baclofen administration: long-term follow-up, review of 40 patients.
Topics: Adult; Baclofen; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Fe | 2004 |
Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity.
Topics: Acute Disease; Animals; Baclofen; Chronic Disease; Excitatory Postsynaptic Potentials; Female; GABA | 2004 |
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter.
Topics: Anesthetics, Inhalation; Animals; Baclofen; Chronic Disease; Electromyography; Halothane; Injections | 2005 |
Administration of baclofen, a gamma-aminobutyric acid type B agonist in the thalamic ventrobasal complex, attenuates allodynia in monoarthritic rats subjected to the ankle-bend test.
Topics: Animals; Ankle Joint; Arthritis, Experimental; Baclofen; Chronic Disease; Disease Models, Animal; Do | 2006 |
Development of baclofen tolerance in a rat model of chronic spasticity and rigidity.
Topics: Animals; Baclofen; Chronic Disease; Drug Tolerance; GABA-A Receptor Agonists; Injections, Spinal; Is | 2006 |
Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.
Topics: Acute Disease; Analgesics; Animals; Baclofen; Behavior, Animal; Chronic Disease; Disease Models, Ani | 2006 |
Chronic hypertension enhances the postsynaptic effect of baclofen in the nucleus tractus solitarius.
Topics: Animals; Baclofen; Chronic Disease; Disease Models, Animal; GABA Agonists; Hypertension; Male; Neuro | 2007 |
Management of intractable pain from a chronic dislocated hip in an adolescent.
Topics: Baclofen; Catheterization; Child; Chronic Disease; Drug Tolerance; Female; Femoral Nerve; GABA Agoni | 2008 |
Phenylethylamine-like properties of baclofen.
Topics: Adult; Aged; Baclofen; Chronic Disease; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; | 1983 |
Effect of sodium valproate and baclofen in tardive dyskinesia: clinical and neuroendocrine studies.
Topics: Adult; Baclofen; Chronic Disease; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Halop | 1980 |
Baclofen therapy for chronic hiccup.
Topics: Anti-Ulcer Agents; Baclofen; Chronic Disease; Cisapride; Dose-Response Relationship, Drug; Female; G | 1995 |
Epileptic focus induced in rat by intrahippocampal cholera toxin: neuronal properties in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclo | 1993 |
Baclofen, a treatment for chronic hiccup.
Topics: Aged; Baclofen; Chronic Disease; Hiccup; Humans; Male; Muscle Relaxants, Central | 1998 |
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxyl | 1998 |
[Chronic hiccups in childhood: usefulness of baclofen].
Topics: Baclofen; Child, Preschool; Chronic Disease; Female; Hiccup; Humans; Muscle Relaxants, Central | 1998 |
The use of baclofen for treatment of chronic hiccups.
Topics: Aged; Baclofen; Chronic Disease; Hiccup; Humans; Male; Muscle Relaxants, Central | 1999 |
The effect of baclofen on spontaneous and evoked behavioural expression of experimental neuropathic chronic pain.
Topics: Animals; Baclofen; Behavior, Animal; Chronic Disease; GABA Agonists; Male; Naloxone; Narcotic Antago | 1999 |
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Admi | 2000 |
Severe respiratory depression by low-dose baclofen in the treatment of chronic hiccups in a patient undergoing CAPD.
Topics: Aged; Baclofen; Chronic Disease; GABA Agonists; Hiccup; Humans; Male; Peritoneal Dialysis, Continuou | 2000 |
gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension.
Topics: Acute Disease; Animals; Baclofen; Blood Pressure; Chronic Disease; Denervation; GABA Agonists; Hyper | 2001 |
[Chronic hiccups].
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Chronic Disease; Esophagitis, Peptic; Female; Hiccup; Huma | 1992 |
Surgical procedures for the relief of acute and chronic pain: caution about intermittent intrathecal injection.
Topics: Acute Disease; Analgesia, Epidural; Baclofen; Chronic Disease; Humans; Infusion Pumps, Implantable; | 1992 |
Intrathecal baclofen for intractable spasticity due to severe brain injury.
Topics: Adult; Baclofen; Brain Injuries; Chronic Disease; Dose-Response Relationship, Drug; Humans; Injectio | 1989 |
Baclofen for intractable hiccups.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Chronic Disease; Drug Administration Schedule; Hiccup; Hum | 1989 |
Atypical facial pain, ectasia of the basilar artery, and baclofen: a case report.
Topics: Aged; Baclofen; Basilar Artery; Chronic Disease; Facial Pain; Female; Humans; Nerve Compression Synd | 1989 |