baclofen and Chemical Dependence studies

baclofen and Chemical Dependence

baclofen has been researched along with Chemical Dependence in 38 studies

Research Excerpts

Excerpt	Relevance	Reference
"Baclofen has been shown to decrease self-administration of GHB in mice and reduce relapse in a case series of GHB-dependent patients."	2.87	Baclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial. ( Beurmanjer, H; de Jong, CAJ; Dijkstra, BAG; Kamal, RM; Schellekens, AFA, 2018)
"Baclofen was well tolerated; patients reported mild side effects such as fatigue, nausea, dry mouth, excessive sweating, and depressive feelings."	2.80	Baclofen as relapse prevention in the treatment of gamma-hydroxybutyrate dependence: a case series. ( De Jong, CA; Dijkstra, BA; Kamal, RM; Loonen, AJ, 2015)
"Baclofen is a psychotropic drug and its recreational use among adolescents and young adults represent a serious problem and should be considered by healthcare professionals."	2.66	Baclofen overdose following recreational use in adolescents and young adults: A case report and review of the literature. ( Abbara, C; Beloncle, F; Briet, M; Drevin, G; Ghamrawi, S, 2020)
"The primary analysis quantified opioid overdose risk across 7 prescription opioid-skeletal muscle relaxant therapies and a negative control outcome (sepsis) to assess potential confounding by unmeasured illicit opioid use."	1.72	Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. ( Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM, 2022)
"Baclofen (BLF) has been prescribed in the UK since 1972 for the alleviation of spasticity."	1.62	Baclofen: To Screen or Not to Screen in Postmortem Blood? ( Murphy, KG; Nahar, LK; Paterson, S, 2021)
" At 100 mg/kg, CGP35348 shifted the dose-response curves of baclofen and SKF97541 to the right but not those of GHB and GBL; at 320 mg/kg, CGP35348 shifted the curves of all four compounds to the right."	1.34	Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348. ( Coop, A; Koek, W; Mercer, SL, 2007)
"Pretreatment with baclofen (1."	1.32	Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat. ( Collu, M; Fadda, P; Fratta, W; Fresu, A; Scherma, M, 2003)
" In contrast to earlier reports, no increase in the plasma half-life of elimination of baclofen could be observed (t1/2 = 4."	1.27	Pharmacokinetics in baclofen overdose. ( Anderson, P; Nohér, H; Swahn, CG, 1984)
"We present the case of a spastic quadriplegic who developed mental symptoms which resolved when his Baclofen was discontinued."	1.27	Reversible electroencephalogram changes associated with administration of baclofen in a quadriplegic patient: case report. ( Lee, L; Riley, TL; Wainapel, SF, 1986)

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (21.05)	18.7374
1990's	1 (2.63)	18.2507
2000's	11 (28.95)	29.6817
2010's	13 (34.21)	24.3611
2020's	5 (13.16)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

8 (21.05)

18.7374

1990's

1 (2.63)

18.2507

2000's

11 (28.95)

29.6817

2010's

13 (34.21)

24.3611

2020's

5 (13.16)

2.80

Authors

Authors	Studies
Khan, NF	1
Bykov, K	1
Barnett, ML	1
Glynn, RJ	1
Vine, SM	1
Gagne, JJ	1
Reynoard, J	1
Schmitt, C	1
Torrents, R	1
Simon, N	1
Nahar, LK	1
Murphy, KG	1
Paterson, S	1
Drevin, G	1
Briet, M	1
Ghamrawi, S	1
Beloncle, F	1
Abbara, C	1
Joshi, YB	1
Friend, SF	1
Jimenez, B	1
Steiger, LR	1
Hamel Sénécal, L	1
Chrétien, B	1
Jean-Jacques, PY	1
Lelong Boulouard, V	1
Cohen, D	1
Le Boisselier, R	1
Beurmanjer, H	1
Kamal, RM	3
de Jong, CAJ	1
Dijkstra, BAG	1
Schellekens, AFA	1
Hardman, MI	1
Sprung, J	1
Weingarten, TN	1
Paino, M	1
Aletraris, L	1
Roman, PM	1
Agabio, R	1
Preti, A	1
Gessa, GL	1
Masi, G	1
Mucci, M	1
Liboni, F	1
Ferrari, A	1
Sicca, F	1
Phillips, TJ	1
Reed, C	1
Besson, J	1
Khazaal, Y	1
Tomei, A	1
Grivel, J	1
Zullino, D	1
Loonen, AJ	1
Dijkstra, BA	2
De Jong, CA	2
Schellekens, A	1
Miranda, F	1
Jiménez, JC	1
Cedillo, LN	1
Sandoval-Sánchez, A	1
Millán-Mejía, P	1
Sánchez-Castillo, H	1
Velázquez-Martínez, DN	1
Bell, J	1
Collins, R	1
Lile, JA	1
Kelly, TH	1
Hays, LR	1
Samokhvalov, AV	1
Paton-Gay, CL	1
Balchand, K	1
Rehm, J	1
Fadda, P	1
Scherma, M	1
Fresu, A	1
Collu, M	1
Fratta, W	1
Bartoletti, M	2
Gubellini, C	1
Ricci, F	2
Gaiardi, M	2
Bowery, NG	1
Heinzerling, KG	1
Shoptaw, S	2
Peck, JA	1
Yang, X	1
Liu, J	1
Roll, J	1
Ling, W	3
Rawson, R	1
Koek, W	1
Mercer, SL	1
Coop, A	1
Ameisen, O	1
Abramson, SI	1
Holmes, AA	1
Hagberg, CA	1
DeFeudis, FV	1
Anderson, P	1
Nohér, H	1
Swahn, CG	1
Seyfert, S	2
Straschill, M	1
May, CR	1
Haubenstock, A	1
Hruby, K	1
Jäger, U	1
Lenz, K	1
Kraft, D	1
Wagner, K	1
Xi, ZX	1
Stein, EA	1
Cousins, MS	1
Roberts, DC	1
de Wit, H	1
Hulinder, B	1
Ostman, O	1
Wainapel, SF	1
Lee, L	1
Riley, TL	1

Studies

Khan, NF

Bykov, K

Barnett, ML

Glynn, RJ

Vine, SM

Gagne, JJ

Reynoard, J

Schmitt, C

Torrents, R

Simon, N

Nahar, LK

Murphy, KG

Paterson, S

Drevin, G

Briet, M

Ghamrawi, S

Beloncle, F

Abbara, C

Joshi, YB

Friend, SF

Jimenez, B

Steiger, LR

Hamel Sénécal, L

Chrétien, B

Jean-Jacques, PY

Lelong Boulouard, V

Cohen, D

Le Boisselier, R

Beurmanjer, H

Kamal, RM

de Jong, CAJ

Dijkstra, BAG

Schellekens, AFA

Hardman, MI

Sprung, J

Weingarten, TN

Paino, M

Aletraris, L

Roman, PM

Agabio, R

Preti, A

Gessa, GL

Masi, G

Mucci, M

Liboni, F

Ferrari, A

Sicca, F

Phillips, TJ

Reed, C

Besson, J

Khazaal, Y

Tomei, A

Grivel, J

Zullino, D

Loonen, AJ

Dijkstra, BA

De Jong, CA

Schellekens, A

Miranda, F

Jiménez, JC

Cedillo, LN

Sandoval-Sánchez, A

Millán-Mejía, P

Sánchez-Castillo, H

Velázquez-Martínez, DN

Bell, J

Collins, R

Lile, JA

Kelly, TH

Hays, LR

Samokhvalov, AV

Paton-Gay, CL

Balchand, K

Rehm, J

Fadda, P

Scherma, M

Fresu, A

Collu, M

Fratta, W

Bartoletti, M

Gubellini, C

Ricci, F

Gaiardi, M

Bowery, NG

Heinzerling, KG

Shoptaw, S

Peck, JA

Yang, X

Liu, J

Roll, J

Ling, W

Rawson, R

Koek, W

Mercer, SL

Coop, A

Ameisen, O

Abramson, SI

Holmes, AA

Hagberg, CA

DeFeudis, FV

Anderson, P

Nohér, H

Swahn, CG

Seyfert, S

Straschill, M

May, CR

Haubenstock, A

Hruby, K

Jäger, U

Lenz, K

Kraft, D

Wagner, K

Xi, ZX

Stein, EA

Cousins, MS

Roberts, DC

de Wit, H

Hulinder, B

Ostman, O

Wainapel, SF

Lee, L

Riley, TL

Reviews

8 reviews available for baclofen and Chemical Dependence

Article	Year
Toxicological considerations in the prescription of baclofen for the treatment of substance use disorders. Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:4 Topics: Alcoholism; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; Humans; Off-Label	2020
Baclofen overdose following recreational use in adolescents and young adults: A case report and review of the literature. Forensic science international, 2020, Volume: 316 Topics: Adolescent; Baclofen; Chromatography, Liquid; Drug Overdose; GABA-B Receptor Agonists; Humans; Male;	2020
Acute phenibut withdrawal: A comprehensive literature review and illustrative case report. Bosnian journal of basic medical sciences, 2019, May-20, Volume: 19, Issue:2 Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor	2019
Efficacy and tolerability of baclofen in substance use disorders: a systematic review. European addiction research, 2013, Volume: 19, Issue:6 Topics: Baclofen; GABA-B Receptor Agonists; Humans; Randomized Controlled Trials as Topic; Substance Withdra	2013
Targeting GABAB receptors for anti-abuse drug discovery. Expert opinion on drug discovery, 2014, Volume: 9, Issue:11 Topics: Animals; Baclofen; Drug Discovery; Humans; Receptors, GABA-B; Substance-Related Disorders	2014
GABAB receptor: a site of therapeutic benefit. Current opinion in pharmacology, 2006, Volume: 6, Issue:1 Topics: Animals; Baclofen; Brain; Clinical Trials as Topic; Cognition; Drug Evaluation, Preclinical; Epileps	2006
Management of methamphetamine abuse and dependence. Current psychiatry reports, 2006, Volume: 8, Issue:5 Topics: Baclofen; Benzhydryl Compounds; Brain; Bupropion; Cognition Disorders; Cognitive Behavioral Therapy;	2006
GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings. Drug and alcohol dependence, 2002, Feb-01, Volume: 65, Issue:3 Topics: Animals; Baclofen; Brain; Dopamine; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid	2002

Article

Year

Toxicological considerations in the prescription of baclofen for the treatment of substance use disorders.

Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:4

Topics: Alcoholism; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; Humans; Off-Label

2020

Baclofen overdose following recreational use in adolescents and young adults: A case report and review of the literature.

Forensic science international, 2020, Volume: 316

Topics: Adolescent; Baclofen; Chromatography, Liquid; Drug Overdose; GABA-B Receptor Agonists; Humans; Male;

2020

Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.

Bosnian journal of basic medical sciences, 2019, May-20, Volume: 19, Issue:2

Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor

2019

Efficacy and tolerability of baclofen in substance use disorders: a systematic review.

European addiction research, 2013, Volume: 19, Issue:6

Topics: Baclofen; GABA-B Receptor Agonists; Humans; Randomized Controlled Trials as Topic; Substance Withdra

2013

Targeting GABAB receptors for anti-abuse drug discovery.

Expert opinion on drug discovery, 2014, Volume: 9, Issue:11

Topics: Animals; Baclofen; Drug Discovery; Humans; Receptors, GABA-B; Substance-Related Disorders

2014

GABAB receptor: a site of therapeutic benefit.

Current opinion in pharmacology, 2006, Volume: 6, Issue:1

Topics: Animals; Baclofen; Brain; Clinical Trials as Topic; Cognition; Drug Evaluation, Preclinical; Epileps

2006

Management of methamphetamine abuse and dependence.

Current psychiatry reports, 2006, Volume: 8, Issue:5

Topics: Baclofen; Benzhydryl Compounds; Brain; Bupropion; Cognition Disorders; Cognitive Behavioral Therapy;

2006

GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings.

Drug and alcohol dependence, 2002, Feb-01, Volume: 65, Issue:3

Topics: Animals; Baclofen; Brain; Dopamine; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid

2002

Trials

4 trials available for baclofen and Chemical Dependence

Article	Year
Baclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial. CNS drugs, 2018, Volume: 32, Issue:5 Topics: Adult; Ambulatory Care; Baclofen; Female; GABA-B Receptor Agonists; Humans; Male; Secondary Preventi	2018
Baclofen as relapse prevention in the treatment of gamma-hydroxybutyrate dependence: a case series. Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3 Topics: Adult; Anesthetics; Baclofen; Drug Administration Schedule; Female; GABA-B Receptor Agonists; Humans	2015
Baclofen as relapse prevention in the treatment of Gamma- Hydroxybutyrate (GHB) dependence: an open label study. BMC psychiatry, 2015, Apr-28, Volume: 15 Topics: Adult; Baclofen; Clinical Protocols; Craving; Female; GABA Agonists; Humans; Male; Quality of Life;	2015
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence. Drug and alcohol dependence, 2006, Dec-01, Volume: 85, Issue:3 Topics: Adult; Amines; Anti-Anxiety Agents; Baclofen; Central Nervous System Stimulants; Cyclohexanecarboxyl	2006

Article

Year

Baclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial.

CNS drugs, 2018, Volume: 32, Issue:5

Topics: Adult; Ambulatory Care; Baclofen; Female; GABA-B Receptor Agonists; Humans; Male; Secondary Preventi

2018

Baclofen as relapse prevention in the treatment of gamma-hydroxybutyrate dependence: a case series.

Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3

Topics: Adult; Anesthetics; Baclofen; Drug Administration Schedule; Female; GABA-B Receptor Agonists; Humans

2015

Baclofen as relapse prevention in the treatment of Gamma- Hydroxybutyrate (GHB) dependence: an open label study.

BMC psychiatry, 2015, Apr-28, Volume: 15

Topics: Adult; Baclofen; Clinical Protocols; Craving; Female; GABA Agonists; Humans; Male; Quality of Life;

2015

Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence.

Drug and alcohol dependence, 2006, Dec-01, Volume: 85, Issue:3

Topics: Adult; Amines; Anti-Anxiety Agents; Baclofen; Central Nervous System Stimulants; Cyclohexanecarboxyl

2006

Other Studies

26 other studies available for baclofen and Chemical Dependence

Article	Year
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. Neurology, 2022, 09-27, Volume: 99, Issue:13 Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort St	2022
Baclofen: To Screen or Not to Screen in Postmortem Blood? Journal of analytical toxicology, 2021, Jul-10, Volume: 45, Issue:6 Topics: Autopsy; Baclofen; Gabapentin; Humans; Pregabalin; Substance-Related Disorders	2021
Dissociative Intoxication and Prolonged Withdrawal Associated With Phenibut: A Case Report. Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:4 Topics: Adult; Baclofen; Delirium; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawa	2017
A Case of Drug Dependence Syndrome to Baclofen Following High-Dose Therapy. Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:3 Topics: Baclofen; Female; GABA-B Receptor Agonists; Humans; Middle Aged; Substance Withdrawal Syndrome; Subs	2018
The use of off-label medications in substance abuse treatment programs. Substance abuse, 2020, Volume: 41, Issue:3 Topics: Accreditation; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antiemetics; Baclofen; Clonidi	2020
Self-induced multiple comas with recreational baclofen overdoses in an adolescent girl. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:6 Topics: Adolescent; Baclofen; Coma; Diagnostic Errors; Drug Overdose; Female; Humans; Muscle Relaxants, Cent	2013
[Addiction]. Revue medicale suisse, 2015, Jan-14, Volume: 11, Issue:456-457 Topics: Alcoholism; Baclofen; Cell Phone; Empathy; GABA-B Receptor Agonists; Humans; Substance-Related Disor	2015
The GABA-B antagonist 2-hydroxysaclofen reverses the effects of baclofen on the discriminative stimulus effects of D-amphetamine in the conditioned taste aversion procedure. Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1 Topics: Animals; Baclofen; Central Nervous System Stimulants; Conditioning, Psychological; Dextroamphetamine	2009
Gamma-butyrolactone (GBL) dependence and withdrawal. Addiction (Abingdon, England), 2011, Volume: 106, Issue:2 Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, D	2011
Separate and combined effects of the GABA(B) agonist baclofen and Δ9-THC in humans discriminating Δ9-THC. Drug and alcohol dependence, 2012, Nov-01, Volume: 126, Issue:1-2 Topics: Adolescent; Adult; Baclofen; Blood Pressure; Body Temperature; Body Temperature Regulation; Demograp	2012
Phenibut dependence. BMJ case reports, 2013, Feb-06, Volume: 2013 Topics: Adult; Baclofen; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives;	2013
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat. Synapse (New York, N.Y.), 2003, Volume: 50, Issue:1 Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Ag	2003
The GABAB agonist baclofen blocks the expression of sensitisation to the locomotor stimulant effect of amphetamine. Behavioural pharmacology, 2004, Volume: 15, Issue:5-6 Topics: Amphetamine; Animals; Baclofen; Central Nervous System Stimulants; GABA Agonists; Male; Motor Activi	2004
A GABA(B) agonist reverses the behavioral sensitization to morphine in rats. Psychopharmacology, 2007, Volume: 192, Issue:1 Topics: Animals; Baclofen; Behavior, Animal; Drug Administration Schedule; Drug Delivery Systems; GABA Agoni	2007
Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348. Psychopharmacology, 2007, Volume: 192, Issue:3 Topics: 4-Butyrolactone; Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; GABA Agonists; GABA	2007
Baclofen as a craving-suppressing agent. CNS drugs, 2007, Volume: 21, Issue:8 Topics: Baclofen; GABA Agonists; Humans; Substance-Related Disorders	2007
Awake insertion of the Bonfils Retromolar Intubation Fiberscope in five patients with anticipated difficult airways. Anesthesia and analgesia, 2008, Volume: 106, Issue:4 Topics: Accidents, Traffic; Adult; Aged; Baclofen; Body Size; Cervical Vertebrae; Equipment Design; Fiber Op	2008
gamma-Aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions. Drug and alcohol dependence, 1984, Volume: 14, Issue:2 Topics: Animals; Baclofen; Brain; Drug Tolerance; Endorphins; GABA Antagonists; gamma-Aminobutyric Acid; Hum	1984
Pharmacokinetics in baclofen overdose. Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:1 Topics: Absorption; Administration, Oral; Adult; Baclofen; Blood Gas Analysis; Female; Gas Chromatography-Ma	1984
[Electroencephalographic changes induced by baclofen]. EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1982, Volume: 13, Issue:4 Topics: Adult; Aged; Baclofen; Electroencephalography; Evoked Potentials; Female; Humans; Male; Middle Aged;	1982
Baclofen overdose. Annals of emergency medicine, 1983, Volume: 12, Issue:3 Topics: Adult; Baclofen; Female; Humans; Substance-Related Disorders	1983
Baclofen (Lioresal) intoxication report of 4 cases and review of the literature. Journal of toxicology. Clinical toxicology, 1983, Volume: 20, Issue:1 Topics: Adult; Aged; Baclofen; Female; Humans; Male; Middle Aged; Substance-Related Disorders	1983
[Baclofen toxicity during intermittent renal dialysis (author's transl)]. Der Nervenarzt, 1981, Volume: 52, Issue:10 Topics: Adult; Baclofen; Electroencephalography; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal	1981
Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3 Topics: Animals; Baclofen; Behavior, Animal; Dopamine; Electrodes; GABA Agonists; Heroin; Limbic System; Mal	1999
[Baclofen--a new agent used by addicts]. Lakartidningen, 1987, Nov-04, Volume: 84, Issue:45 Topics: Adult; Baclofen; Humans; Male; Middle Aged; Substance-Related Disorders	1987
Reversible electroencephalogram changes associated with administration of baclofen in a quadriplegic patient: case report. Paraplegia, 1986, Volume: 24, Issue:2 Topics: Adult; Baclofen; Cervical Vertebrae; Delta Rhythm; Electroencephalography; Fractures, Bone; Humans;	1986

Article

Year

Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.

Neurology, 2022, 09-27, Volume: 99, Issue:13

Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort St

2022

Baclofen: To Screen or Not to Screen in Postmortem Blood?

Journal of analytical toxicology, 2021, Jul-10, Volume: 45, Issue:6

Topics: Autopsy; Baclofen; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2021

Dissociative Intoxication and Prolonged Withdrawal Associated With Phenibut: A Case Report.

Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:4

Topics: Adult; Baclofen; Delirium; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawa

2017

A Case of Drug Dependence Syndrome to Baclofen Following High-Dose Therapy.

Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:3

Topics: Baclofen; Female; GABA-B Receptor Agonists; Humans; Middle Aged; Substance Withdrawal Syndrome; Subs

2018

The use of off-label medications in substance abuse treatment programs.

Substance abuse, 2020, Volume: 41, Issue:3

Topics: Accreditation; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antiemetics; Baclofen; Clonidi

2020

Self-induced multiple comas with recreational baclofen overdoses in an adolescent girl.

Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:6

Topics: Adolescent; Baclofen; Coma; Diagnostic Errors; Drug Overdose; Female; Humans; Muscle Relaxants, Cent

2013

[Addiction].

Revue medicale suisse, 2015, Jan-14, Volume: 11, Issue:456-457

Topics: Alcoholism; Baclofen; Cell Phone; Empathy; GABA-B Receptor Agonists; Humans; Substance-Related Disor

2015

The GABA-B antagonist 2-hydroxysaclofen reverses the effects of baclofen on the discriminative stimulus effects of D-amphetamine in the conditioned taste aversion procedure.

Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1

Topics: Animals; Baclofen; Central Nervous System Stimulants; Conditioning, Psychological; Dextroamphetamine

2009

Gamma-butyrolactone (GBL) dependence and withdrawal.

Addiction (Abingdon, England), 2011, Volume: 106, Issue:2

Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, D

2011

Separate and combined effects of the GABA(B) agonist baclofen and Δ9-THC in humans discriminating Δ9-THC.

Drug and alcohol dependence, 2012, Nov-01, Volume: 126, Issue:1-2

Topics: Adolescent; Adult; Baclofen; Blood Pressure; Body Temperature; Body Temperature Regulation; Demograp

2012

Phenibut dependence.

BMJ case reports, 2013, Feb-06, Volume: 2013

Topics: Adult; Baclofen; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives;

2013

Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat.

Synapse (New York, N.Y.), 2003, Volume: 50, Issue:1

Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Ag

2003

The GABAB agonist baclofen blocks the expression of sensitisation to the locomotor stimulant effect of amphetamine.

Behavioural pharmacology, 2004, Volume: 15, Issue:5-6

Topics: Amphetamine; Animals; Baclofen; Central Nervous System Stimulants; GABA Agonists; Male; Motor Activi

2004

A GABA(B) agonist reverses the behavioral sensitization to morphine in rats.

Psychopharmacology, 2007, Volume: 192, Issue:1

Topics: Animals; Baclofen; Behavior, Animal; Drug Administration Schedule; Drug Delivery Systems; GABA Agoni

2007

Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.

Psychopharmacology, 2007, Volume: 192, Issue:3

Topics: 4-Butyrolactone; Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; GABA Agonists; GABA

2007

Baclofen as a craving-suppressing agent.

CNS drugs, 2007, Volume: 21, Issue:8

Topics: Baclofen; GABA Agonists; Humans; Substance-Related Disorders

2007

Awake insertion of the Bonfils Retromolar Intubation Fiberscope in five patients with anticipated difficult airways.

Anesthesia and analgesia, 2008, Volume: 106, Issue:4

Topics: Accidents, Traffic; Adult; Aged; Baclofen; Body Size; Cervical Vertebrae; Equipment Design; Fiber Op

2008

gamma-Aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions.

Drug and alcohol dependence, 1984, Volume: 14, Issue:2

Topics: Animals; Baclofen; Brain; Drug Tolerance; Endorphins; GABA Antagonists; gamma-Aminobutyric Acid; Hum

1984

Pharmacokinetics in baclofen overdose.

Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:1

Topics: Absorption; Administration, Oral; Adult; Baclofen; Blood Gas Analysis; Female; Gas Chromatography-Ma

1984

[Electroencephalographic changes induced by baclofen].

EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1982, Volume: 13, Issue:4

Topics: Adult; Aged; Baclofen; Electroencephalography; Evoked Potentials; Female; Humans; Male; Middle Aged;

1982

Baclofen overdose.

Annals of emergency medicine, 1983, Volume: 12, Issue:3

Topics: Adult; Baclofen; Female; Humans; Substance-Related Disorders

1983

Baclofen (Lioresal) intoxication report of 4 cases and review of the literature.

Journal of toxicology. Clinical toxicology, 1983, Volume: 20, Issue:1

Topics: Adult; Aged; Baclofen; Female; Humans; Male; Middle Aged; Substance-Related Disorders

1983

[Baclofen toxicity during intermittent renal dialysis (author's transl)].

Der Nervenarzt, 1981, Volume: 52, Issue:10

Topics: Adult; Baclofen; Electroencephalography; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal

1981

Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release.

The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

Topics: Animals; Baclofen; Behavior, Animal; Dopamine; Electrodes; GABA Agonists; Heroin; Limbic System; Mal

1999

[Baclofen--a new agent used by addicts].

Lakartidningen, 1987, Nov-04, Volume: 84, Issue:45

Topics: Adult; Baclofen; Humans; Male; Middle Aged; Substance-Related Disorders

1987

Reversible electroencephalogram changes associated with administration of baclofen in a quadriplegic patient: case report.

Paraplegia, 1986, Volume: 24, Issue:2

Topics: Adult; Baclofen; Cervical Vertebrae; Delta Rhythm; Electroencephalography; Fractures, Bone; Humans;

1986