baclofen has been researched along with Cerebral Palsy in 286 studies
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess attainment of individual treatment goals one year after intrathecal baclofen (ITB) pump implantation in individuals with dyskinetic cerebral palsy (CP)." | 9.69 | Attainment of personal goals in the first year of intrathecal baclofen treatment in dyskinetic cerebral palsy: a prospective cohort study. ( Becher, JG; Bonouvrié, LA; Buizer, AI; Haberfehlner, H; Vermeulen, RJ; Vles, JSH, 2023) |
| "Intrathecal baclofen treatment is used for the treatment of dystonia in patients with severe dyskinetic cerebral palsy; however, the current level of evidence for the effect is low." | 9.30 | The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial. ( Becher, JG; Bonouvrié, LA; Buizer, AI; Vermeulen, RJ; Vles, JSH, 2019) |
| "A total of 49 patients with cerebral palsy who had participated in an oral baclofen pharmacokinetic/pharmacodynamic study." | 9.27 | Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy. ( Brunstrom-Hernandez, J; Carleton, BC; Dai, H; Gaedigk, A; He, Y; Jusko, WJ; Leeder, JS; Lewandowski, A; McLaughlin, MJ; Ross, CJD; Thio, LL, 2018) |
| "Intrathecal treatment of baclofen is an excellent method for spasticity management in children with severe cerebral palsy." | 9.24 | Long-term therapy with intrathecal baclofen improves quality of life in children with severe spastic cerebral palsy. ( Gegenleitner, K; Kraus, T; Novak, M; Singer, G; Steinwender, G; Svehlik, M, 2017) |
| "To characterize the population pharmacokinetics (PK) of oral baclofen and assess impact of patient-specific covariates in children with cerebral palsy (CP) in order to support its clinical use." | 9.19 | Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy. ( Brunstrom-Hernandez, JE; Butler, M; Christensen, A; Dai, H; Dosa, NP; Gaebler-Spira, D; Gaedigk, A; He, Y; Hoon, AH; Jusko, WJ; Kennedy, D; Krach, LE; Kuroda, MM; Lackey, S; Leeder, JS; Lewandowski, A; Lopez, C; Lowenhaupt, S; McLaughlin, JF; Roge, D; Schwabe, A; Stashinko, E; Stevenson, RD; Thio, LL; Tilton, A; Vargus-Adams, J, 2014) |
| " Intrathecal baclofen treatment is a potential treatment option for dystonia and has become common practice." | 9.17 | Intrathecal baclofen treatment in dystonic cerebral palsy: a randomized clinical trial: the IDYS trial. ( Becher, JG; Boeschoten, K; Bonouvrié, LA; de Groot, V; Foncke, E; Geytenbeek, J; Soudant, D; Strijers, R; Teernstra, O; van de Ven, PM; van Ouwerkerk, WJ; Vermeulen, RJ; Vles, JS, 2013) |
| "To measure changes in children with severe spastic cerebral palsy (CP) after continuous intrathecal baclofen (ITB) infusion over 18 months and to compare the results with those of a comparison group awaiting treatment." | 9.15 | Controlled study of the effects of continuous intrathecal baclofen infusion in non-ambulant children with cerebral palsy. ( Gray, N; Morton, RE; Vloeberghs, M, 2011) |
| "8) years, with intractable spastic cerebral palsy were randomised to receive a Synchromed pump for continuous infusion of intrathecal baclofen after either 1 month (CITB group) or 6 months (Control group)." | 9.14 | Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial. ( Becher, JG; Hoving, MA; Palmans, LJ; Spincemaille, GH; van Raak, EP; Vles, JS, 2009) |
| "This study assessed the effects of continuous intrathecal infusion of baclofen on the gait of ambulant children with cerebral palsy." | 9.14 | Intrathecal baclofen infusion for ambulant children with cerebral palsy. ( Brochard, S; Bussel, B; Filipetti, P; Remy-Neris, O, 2009) |
| "Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy." | 9.13 | The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008) |
| "To assess the effectiveness of oral baclofen in reducing spasticity and improving function in children with cerebral palsy." | 9.12 | Oral baclofen in children with cerebral palsy: a double-blind cross-over pilot study. ( Hall, K; Lam, LT; O'Flaherty, S; Scheinberg, A, 2006) |
| "Intrathecal baclofen (ITB) therapy can be very effective in the treatment of intractable spasticity, but its effectiveness and safety have not yet been thoroughly studied in children with cerebral palsy (CP)." | 9.12 | Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study. ( Hoving, MA; Palmans, LJ; Sleypen, FA; Spincemaille, GH; van Raak, EP; Vles, JS, 2007) |
| "To describe the efficacy of intrathecal baclofen (ITB) therapy in the management of spasticity in young children with cerebral palsy (CP) and to identify risk factors for complications." | 9.10 | Intrathecal baclofen therapy in children with cerebral palsy: efficacy and complications. ( Hoff, C; Irwin, MC; Murphy, NA, 2002) |
| "The purpose of this article is to describe outcomes of intrathecal baclofen therapy for 29 patients with cerebral palsy, focusing on impairments, functional limitations, and disability." | 9.10 | Functional assessment following intrathecal baclofen therapy in children with spastic cerebral palsy. ( Awaad, R; Awaad, Y; Ham, S; Michon, AM; Munoz, S; Tayem, H, 2003) |
| "Seventeen patients with congenital spastic cerebral palsy and six patients with other forms of spasticity were injected intrathecally with doses of placebo or baclofen, 25 micrograms, 50 micrograms, or 100 micrograms, in a randomized, double-blind manner." | 9.07 | Intrathecal baclofen for spasticity in cerebral palsy. ( Albright, AL; Cervi, A; Singletary, J, 1991) |
| "A double-blind crossover trial against placebo was conducted to assess the effects of the GABA derivative, baclofen, on the disabilities due to muscle spasticity in twenty children suffering from cerebral palsy." | 9.04 | A controlled trial of baclofen in children with cerebral palsy. ( Jackson, AD; Milla, PJ, 1977) |
| "To systematically review the effectiveness of oral baclofen versus placebo or other antispastic oral medications in terms of body function, level of activity, and quality of life in children and adolescents with spastic cerebral palsy who are younger than 18 years." | 8.93 | Effectiveness of Oral Baclofen in the Treatment of Spasticity in Children and Adolescents With Cerebral Palsy. ( Gonzalez, W; Nahuelhual, P; Navarrete-Opazo, AA, 2016) |
| "To determine whether intrathecal baclofen is an effective treatment for spasticity in children with cerebral palsy." | 8.91 | Intrathecal baclofen for treating spasticity in children with cerebral palsy. ( Hasnat, MJ; Rice, JE, 2015) |
| "Intrathecal baclofen (ITB) is an effective treatment for both spasticity and dystonia in people with cerebral palsy (CP)." | 8.85 | Intrathecal baclofen use in adults with cerebral palsy. ( Krach, LE, 2009) |
| "Pregnancy in patients with intrathecal baclofen (ITB) pumps is rare." | 8.85 | Intrathecal baclofen and pregnancy: implications for clinical care. ( Campbell, C; Delaney, G; DeRibaupierre, S; DeVries-Rizzo, M; Levin, S; Warren, D, 2009) |
| "Intrathecal baclofen (ITB) has become a standard treatment for spasticity in patients with cerebral palsy (CP) over the last ten years." | 8.84 | A review of the complications of intrathecal baclofen in patients with cerebral palsy. ( Kolaski, K; Logan, LR, 2007) |
| "Intrathecal baclofen reduces spasticity in individuals with cerebral palsy." | 8.79 | Intrathecal baclofen in cerebral palsy movement disorders. ( Albright, AL, 1996) |
| "To evaluate the effects of intrathecal baclofen pump (ITBP) therapy on hip dysplasia in young patients with cerebral palsy (CP)." | 8.31 | Does intrathecal baclofen therapy decrease the progression of hip displacement in young patients with cerebral palsy? ( Asma, A; Howard, JJ; McManus, M; Miller, F; Rogers, KJ; Shrader, MW; Ulusaloglu, AC, 2023) |
| "Intrathecal baclofen (ITB) therapy is an effective treatment for spasticity and dystonia in children with cerebral palsy (CP)." | 8.31 | A multicenter initiative to reduce intrathecal baclofen pump surgical site infection: a Cerebral Palsy Research Network quality improvement project. ( Albarqawi, L; Bailes, AF; Bollo, RJ; Browd, SR; Gross, PH; Leonard, JR; Raskin, JS; Rocque, BG, 2023) |
| "This study aimed to determine the risk factors for reconstructive hip surgery after intrathecal baclofen pump application in children with cerebral palsy." | 8.31 | Identification of risk factors for reconstructive hip surgery after intrathecal baclofen therapy in children with cerebral palsy. ( Asma, A; Howard, JJ; Miller, F; Rogers, KJ; Shrader, MW; Ulusaloglu, AC, 2023) |
| "The purpose of this study is to describe the efficacy and adverse events of neuraxial anesthesia for post-operative pain control in non-ambulatory children with cerebral palsy with pre-existing intrathecal baclofen (ITB) pumps undergoing hip reconstructive or palliative surgery." | 8.12 | Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps. ( Ball, MA; Davids, JR; Davidson, LT; Kephart, DT; Kulkarni, VA; Tumber, S, 2022) |
| "The purpose of this study was to investigate the incidence of complications in pediatric spastic cerebral palsy (CP) patients weighing less than 20 kg at the time of intrathecal baclofen (ITB) pump implantation and to compare it with spastic CP patients heavier than 20 kg." | 8.12 | Complications of intrathecal baclofen pump treatment in children with spastic cerebral palsy. A comparative analysis of patients weighing over or under 20 kg at the time of implantation. ( Canavese, F; De Coulon, G; Steiger, CN; Tabard-Fougère, A, 2022) |
| "The purpose of this article is to review the effectiveness of epidural blood patch for the treatment of spinal headache and cerebrospinal fluid leak associated with intrathecal baclofen treatment in children with cerebral palsy." | 7.96 | The effectiveness of epidural blood patch in patients with cerebral palsy treated with intrathecal baclofen implantation. ( Dixit, D; Imerci, A; McManus, M; Miller, F; Rogers, K; Sees, JP, 2020) |
| "In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome." | 7.96 | Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020) |
| "The aim is to study access to intrathecal baclofen (ITB) for children with cerebral palsy (CP) in Europe, as an indicator of access to advanced care." | 7.96 | Access to Intrathecal Baclofen Treatment for Children with Cerebral Palsy in European Countries: An SCPE Survey Reveals Important Differences. ( Andersen, GL; Arnaud, C; de la Cruz, J; Himmelmann, K; Horridge, K; Neubauer, D; Påhlman, M; Rackauskaite, G; Vik, T; Virella, D, 2020) |
| "Insertion of an intrathecal baclofen (ITB) pump can provide significant benefits in patients with cerebral palsy (CP)." | 7.96 | Evaluation of Risk Factors for Cerebrospinal Leakage in Pediatric Patients With Cerebral Palsy Treated With Intrathecal Baclofen. ( Imerci, A; Miller, F; Rogers, KJ; Sees, JP, 2020) |
| "Intrathecal baclofen (ITB) pumps used to manage spasticity in children with cerebral palsy (CP) also improve pain outcomes for some but not all patients." | 7.96 | Investigating the Feasibility of a Modified Quantitative Sensory Testing Approach to Profile Sensory Function and Predict Pain Outcomes Following Intrathecal Baclofen Implant Surgery in Cerebral Palsy. ( Barney, CC; Merbler, AM; Simone, DA; Symons, FJ; Walk, D, 2020) |
| "The effect of a continuous intrathecal infusion of baclofen (CITB) was retrospectively studied in 19 ambulatory children with cerebral palsy (aged 12." | 7.88 | The effect of continuous intrathecal baclofen therapy on ambulatory children with cerebral palsy. ( Church, C; Henley, J; Hulbert, R; Miller, F; Niiler, T; Pruszczynski, B; Sees, J, 2018) |
| "To investigate the effect of intrathecal baclofen (ITB) on function and activity in dyskinetic cerebral palsy (CP)." | 7.88 | Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity. ( Askljung, B; Corneliusson, O; Eek, MN; Himmelmann, K; Lindh, K; Olsson, K; Påhlman, M, 2018) |
| "This article details an unreported potential cause of withdrawal symptoms in a patient with cerebral palsy who experienced intrathecal baclofen withdrawal shortly after placement of a baclofen pump with subsequent refill with Gablofen." | 7.88 | An Unreported Cause of Intrathecal Baclofen Withdrawal Symptoms in a Woman With Spastic Cerebral Palsy Who Received Intrathecal Gablofen. ( Duraski, SA; Sayyad, A, 2018) |
| "Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps." | 7.85 | Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017) |
| "To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps." | 7.85 | Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017) |
| "Intrathecal baclofen (ITB) treatment is applied in patients with spastic cerebral palsy (SCP), dystonic cerebral palsy (DCP) and progressive neurological disease (PND)." | 7.83 | The effect of intrathecal baclofen treatment on activities of daily life in children and young adults with cerebral palsy and progressive neurological disorders. ( Becher, J; Bonouvrié, L; Buizer, A; Soudant, D; van Ouwerkerk, W; Vermeulen, RJ; Vles, G, 2016) |
| "Treatment of severe spasticity and dystonia with intrathecal baclofen (ITB) in children has been shown to be effective and has therefore been employed in the Region of Southern Denmark." | 7.81 | Positive experience with intrathecal baclofen treatment in children with severe cerebral palsy. ( Illum, NO; Kjærsgaard-Hansen, L; Overgård, TM; Søe, M, 2015) |
| "To compare patients with operative cerebral palsy with and without an intrathecal baclofen pump (ITB) to determine whether an ITB increases the complexity of scoliosis surgery and/or increases the risk of wound complications." | 7.81 | Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy. ( Asghar, J; Bastrom, TP; Bomar, JD; Newton, PO; Samdani, AF; Scannell, BP; Shah, SA; Sponseller, PD; Yaszay, B, 2015) |
| "A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion." | 7.81 | Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015) |
| "We describe a 6 year-old girl with hydranencephaly who underwent an intrathecal baclofen test dose and developed severe bradycardia." | 7.81 | Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly. ( Cain, N; Kinsman, S; Sechrist, C, 2015) |
| "Implantation of an intrathecal baclofen pump is recommended for children with cerebral palsy as a means to improve care and comfort when other options fail to control severe hypertonia." | 7.80 | Improvements in children with cerebral palsy following intrathecal baclofen: use of the Rehabilitation Institute of Chicago Care and Comfort Caregiver Questionnaire (RIC CareQ). ( Baker, KW; Gaebler-Spira, D; Mutlu, A; Tann, B, 2014) |
| "To investigate the effect of intrathecal baclofen (ITB) on sitting in children with cerebral palsy with severe spasticity; and identify potential sub-groups of patients at particular risk of deterioration." | 7.80 | The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy. ( Gray, N; Vloeberghs, M, 2014) |
| "Little is known about the long-term effects of Continuous intrathecal Baclofen (CITB) therapy in non-ambulant children with intractable spastic Cerebral Palsy (CP)." | 7.79 | Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy. ( Bonouvrié, LA; Hoving, MA; Soudant, DL; van Oostenbrugge, RJ; Vermeulen, RJ; Vles, GF; Vles, JS, 2013) |
| "A foreign-body reaction after intrathecal baclofen pump implantation is a rare complication, which has not been reported previously, and which is associated with negative skin patch tests." | 7.78 | Intrathecal baclofen pump: a foreign-body reaction case report and its solution. ( Assier, H; Bernuz, B; Bisseriex, H; Rech, C; Schnitzler, A; Thiebaut, JB, 2012) |
| "Intrathecal baclofen therapy has been used successfully for intractable spasticity in children with cerebral palsy." | 7.78 | Evaluation of salvage techniques for infected baclofen pumps in pediatric patients with cerebral palsy. ( Fisher, JF; Hester, SM; Lee, MR; Macomson, S; Vender, JR, 2012) |
| "The aim of this retrospective analysis was to determine the impact of intrathecal baclofen (ITB) therapy on motor function in patients with cerebral palsy (CP)." | 7.77 | Intrathecal baclofen and motor function in cerebral palsy. ( Antonello, CE; Motta, F; Stignani, C, 2011) |
| "To determine whether intrathecal baclofen (ITB) changes mortality risk in persons with cerebral palsy (CP)." | 7.76 | Survival of individuals with cerebral palsy receiving continuous intrathecal baclofen treatment: a matched-cohort study. ( Day, SM; Krach, LE; Kriel, RL; Strauss, DJ, 2010) |
| "The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy." | 7.76 | Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge? ( Jahnsen, R; Lofterod, B; Ramstad, K; Skjeldal, OH, 2010) |
| "Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy." | 7.76 | Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010) |
| "Baclofen is widely used to control spasticity in children with cerebral palsy." | 7.76 | Long-term oral baclofen treatment in a child with cerebral palsy: electroencephalographic changes and clinical adverse effects. ( De Rinaldis, M; Gennaro, L; Losito, L; Trabacca, A, 2010) |
| "To study the efficacy and safety of intrathecal baclofen therapy (ITB) in wheelchair-dependent adults with cerebral palsy." | 7.76 | Intrathecal baclofen in cerebral palsy. A retrospective study of 25 wheelchair-assisted adults. ( Chenet, A; Ferrapie, AL; Gambart, G; Gay, S; Ménégalli Bogeli, D; Menei, P; Perrouin Verbe, B; Richard, I; Tassëel Ponche, S, 2010) |
| "Prospective studies that address both efficacy and safety of continuous infusion of intrathecal baclofen (CITB) in children with spastic cerebral palsy (CP), and that use outcome measures beyond muscle tone are lacking." | 7.75 | Safety and one-year efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy. ( Gorter, JW; Hoving, MA; Spincemaille, GH; van Kleef, M; van Kranen-Mastenbroek, VH; van Raak, EP; Vles, JS, 2009) |
| "To assess the effect of continuous intrathecal baclofen infusion (ITB) on gait parameters of ambulant children with cerebral palsy (CP)." | 7.75 | Changes in gait following continuous intrathecal baclofen infusion in ambulant children and young adults with cerebral palsy. ( Brochard, S; Filipetti, P; Lempereur, M; Rémy-Néris, O, 2009) |
| "Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries." | 7.74 | Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008) |
| "Intrathecal baclofen (ITB) is a well-established method of treating spasticity in children with cerebral palsy." | 7.74 | The role of intrathecal baclofen in the management of primary and secondary dystonia in children. ( Tsegaye, M; Vloeberghs, MH; Woon, K, 2007) |
| "To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort." | 7.74 | The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007) |
| "Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis." | 7.74 | Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007) |
| "The literature available shows that spasticity in patients with cerebral palsy (CP) is reduced by intrathecal baclofen (ITB) treatment, and various studies suggest that this treatment can also be used in dystonic patients." | 7.74 | Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. ( Antonello, CE; Motta, F; Stignani, C, 2008) |
| "In a Dutch national study, we recently established the effectiveness and safety of continuous intrathecal baclofen infusion (CITB) in children with intractable spastic cerebral palsy (CP)." | 7.74 | Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis. ( Ament, AJ; Evers, SM; Hoving, MA; van Raak, EP; Vles, JS, 2008) |
| " At present there are two very promising therapeutic alternatives for patients with infantile cerebral palsy: Botulinum toxin, which we already have a great deal of experience with, and intrathecal treatment with baclofen." | 7.73 | [Intrathecal baclofen and Botulinum toxin in infantile cerebral palsy]. ( Alvarez-Garijo, JA; Barbero, P; Mulas, F; Téllez de Meneses, M, 2005) |
| "The authors evaluated a case series of 5 patients with cerebral palsy and a previously placed subcutaneous reservoir for continuous intrathecal baclofen infusion to control spasticity who underwent spinal arthrodesis with posterior instrumentation for progressive neuromuscular scoliosis deformities." | 7.73 | Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion. ( Kanev, PM; Segal, LS; Wallach, DM, 2005) |
| "The objective of this study was to analyze the relationship between epilepsy and intrathecal baclofen by investigating a consecutive sample of 150 children with cerebral palsy or spasticity of cerebral origin who underwent intrathecal baclofen." | 7.73 | Epilepsy and intrathecal baclofen therapy in children with cerebral palsy. ( Buonaguro, V; Curci, D; Iuorno, T; Monforte, S; Motta, F; Scelsa, B, 2005) |
| "To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy." | 7.73 | Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy. ( Gilpin, P; Jarrett, L; Leary, SM; Lockley, L; Rodriguez, L; Stevenson, VL, 2006) |
| "To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia." | 7.72 | Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003) |
| " The aim of this paper is to present the result of intrathecal baclofen infusion in treatment of spasticity in patients with cerebral palsy." | 7.72 | [Intrathecal baclofen for treatment of spasticity in patient with cerebral palsy--a preliminary report]. ( Grottel, K; Huber, J; Idzior, M; Jóźwiak, M; Szulc, A, 2003) |
| "Mechanical measures were made in studying six participants with cerebral palsy who were undergoing treatment for spasticity using intrathecal baclofen therapy." | 7.72 | Mechanical measurements of the effects of intrathecal baclofen dosage adjustments in cerebral palsy: a pilot study. ( Gaebler-Spira, D; Schmit, BD, 2004) |
| "The purpose of this study was to assess whether reduction of muscle tone by continuous intrathecal baclofen infusion affects the progression of hip subluxation in persons with cerebral palsy." | 7.72 | Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion. ( Abbott, R; Bloom, KK; Brooks, WH; Gilmartin, RC; Krach, LE; Kriel, RL; Madsen, JR; McLaughlin, JF; Nadell, JM; Storrs, BB; Swift, DM; Ward, JD, 2004) |
| "In this 1-week trial, repetitive administration of baclofen reduced the frequency of emesis and the total number of acid refluxes in neurologically impaired children with GERD." | 7.72 | Effect of baclofen on emesis and 24-hour esophageal pH in neurologically impaired children with gastroesophageal reflux disease. ( Hirayama, S; Ida, S; Kawahara, H; Kawai, M; Yoshimura, N, 2004) |
| "After repair of the catheter of an implanted intrathecal baclofen (ITB) delivery system, a 17-year-old man with cerebral palsy developed acute lower-extremity hypotonia." | 7.71 | Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. ( Murphy, NA, 2002) |
| "To determine if the continuous intrathecal delivery of baclofen will control spastic hypertonia caused by long-standing cerebral palsy (CP)." | 7.71 | Continuously infused intrathecal baclofen over 12 months for spastic hypertonia in adolescents and adults with cerebral palsy. ( Grabb, P; Guin-Renfroe, S; Hadley, MN; Law, C; Meythaler, JM, 2001) |
| "To determine whether continuous intrathecal baclofen infusion (CIBI) would decrease spasticity and improve function in children with spastic cerebral palsy." | 7.71 | Continuous intrathecal baclofen infusion for children with cerebral palsy: a pilot study. ( Chaseling, R; Dexter, M; O'Flaherty, S; Scheinberg, A, 2001) |
| "We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps." | 7.71 | Reversible coma in children after improper baclofen pump insertion. ( Anderson, KJ; Brown, K; Farmer, JP, 2002) |
| "Dystonia diminished in 10 of 12 patients whose average daily dose of intrathecal baclofen was 575 microg." | 7.70 | Infusion of intrathecal baclofen for generalized dystonia in cerebral palsy. ( Albright, AL; Barry, MJ; Painter, MJ; Shultz, B, 1998) |
| "Intrathecal baclofen infusion (IBI) is an effective treatment for spasticity secondary to cerebral palsy (CP)." | 7.70 | Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy. ( Albright, AL; Gerszten, PC; Johnstone, GF, 1998) |
| "The purpose of the study was to analyze the relative cost of selective functional posterior rhizotomy (SFPR) and continuous intrathecal baclofen in the treatment of children with severe spastic quadriplegia related to cerebral palsy." | 7.69 | Cost analysis of continuous intrathecal baclofen versus selective functional posterior rhizotomy in the treatment of spastic quadriplegia associated with cerebral palsy. ( Daneshvar, H; Evans, D; Kestle, JR; Steinbok, P, 1995) |
| "Five patients with generalized dystonia who were refractory to oral medications were treated by continuous intrathecal baclofen infusion." | 7.69 | Continuous intrathecal baclofen infusion for symptomatic generalized dystonia. ( Albright, AL; Barron, W; Barry, MJ; Fasick, P; Shultz, B, 1996) |
| "Dystonia was associated with cerebral palsy in 71% of participants." | 6.70 | Intrathecal baclofen for generalized dystonia. ( Albright, AL; Barry, MJ; Ferson, SS; Shafton, DH, 2001) |
| "Because of severe spasticity, many of these patients undergo intrathecal baclofen pump placement before, during, or after posterior spinal fusion." | 6.52 | Scoliosis, spinal fusion, and intrathecal baclofen pump implantation. ( Scannell, B; Yaszay, B, 2015) |
| "To assess attainment of individual treatment goals one year after intrathecal baclofen (ITB) pump implantation in individuals with dyskinetic cerebral palsy (CP)." | 5.69 | Attainment of personal goals in the first year of intrathecal baclofen treatment in dyskinetic cerebral palsy: a prospective cohort study. ( Becher, JG; Bonouvrié, LA; Buizer, AI; Haberfehlner, H; Vermeulen, RJ; Vles, JSH, 2023) |
| "The aim of the study was to identify oral baclofen dosing variability at steady state based on weight and Gross Motor Function Classification System level using a retrospective cross-sectional study design." | 5.56 | Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy. ( McGhee, E; McLaughlin, MJ; Ratnasingam, D, 2020) |
| "Change of spasticity was evaluated using the Modified Ashworth Scale." | 5.46 | Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury. ( Chae, M; Chang, JW; Chang, WS; Cho, HE; Cho, SR; Lee, KC; Yoon, YK, 2017) |
| " Following botulinum toxin A treatment, clinical improvement led to the gradual reduction of baclofen or tizanidine dosing to one-third of the former dose." | 5.43 | Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity. ( Aksoy, SN; Dai, AI; Demiryürek, AT, 2016) |
| "Treatment of children with movement disorders associated with CP increased slowly in the 1970s and 1980s but accelerated rapidly in the 1990s with the introduction of lumbar dorsal rhizotomies and intrathecal baclofen." | 5.41 | Spasticity and movement disorders in cerebral palsy. ( Albright, AL, 2023) |
| "Spasticity is the major etiology for hip dislocation in nonambulatory cerebral palsy patients." | 5.38 | A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients. ( Ayyangar, RN; Caird, MS; Craig, CL; Farley, FA; Hensinger, RN; Hurvitz, EA; Nowicki, P; Silva, S; Vanderhave, KL, 2012) |
| "Although spasticity is a common symptom in children with cerebral palsy, weakness may be a much greater contributor to disability." | 5.35 | Oral baclofen increases maximal voluntary neuromuscular activation of ankle plantar flexors in children with spasticity due to cerebral palsy. ( Kukke, S; McGill, K; Rose, J; Sanger, TD; Sherman-Levine, S; van Doornik, J, 2008) |
| "Although excessive weight gain is not a common problem in children with cerebral origin spasticity, increased weight-gain velocity is prevalent in children receiving ITB therapy." | 5.33 | Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy. ( Ayyangar, RN; Fox, MA; McCoy, AA; Schaubel, DE, 2006) |
| "After several reports of new-onset seizures in children treated with oral baclofen at our institution, we reviewed our experience regarding possible effects of baclofen on seizure induction in a childhood movement disorders program over a 2-year period." | 5.32 | Oral baclofen in cerebral palsy: possible seizure potentiation? ( Hansel, CR; Hansel, DE; Hoon, AH; Johnston, MV; Levey, EB; Madden, L; Reinhardt, EM; Shindle, MK, 2003) |
| "Intrathecal baclofen treatment is used for the treatment of dystonia in patients with severe dyskinetic cerebral palsy; however, the current level of evidence for the effect is low." | 5.30 | The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial. ( Becher, JG; Bonouvrié, LA; Buizer, AI; Vermeulen, RJ; Vles, JSH, 2019) |
| "Oral baclofen improves cerebral spasticity mildly, but its activity is limited because of its poor lipid solubility." | 5.29 | Baclofen in the treatment of cerebral palsy. ( Albright, AL, 1996) |
| "A total of 49 patients with cerebral palsy who had participated in an oral baclofen pharmacokinetic/pharmacodynamic study." | 5.27 | Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy. ( Brunstrom-Hernandez, J; Carleton, BC; Dai, H; Gaedigk, A; He, Y; Jusko, WJ; Leeder, JS; Lewandowski, A; McLaughlin, MJ; Ross, CJD; Thio, LL, 2018) |
| "Intrathecal treatment of baclofen is an excellent method for spasticity management in children with severe cerebral palsy." | 5.24 | Long-term therapy with intrathecal baclofen improves quality of life in children with severe spastic cerebral palsy. ( Gegenleitner, K; Kraus, T; Novak, M; Singer, G; Steinwender, G; Svehlik, M, 2017) |
| "To characterize the population pharmacokinetics (PK) of oral baclofen and assess impact of patient-specific covariates in children with cerebral palsy (CP) in order to support its clinical use." | 5.19 | Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy. ( Brunstrom-Hernandez, JE; Butler, M; Christensen, A; Dai, H; Dosa, NP; Gaebler-Spira, D; Gaedigk, A; He, Y; Hoon, AH; Jusko, WJ; Kennedy, D; Krach, LE; Kuroda, MM; Lackey, S; Leeder, JS; Lewandowski, A; Lopez, C; Lowenhaupt, S; McLaughlin, JF; Roge, D; Schwabe, A; Stashinko, E; Stevenson, RD; Thio, LL; Tilton, A; Vargus-Adams, J, 2014) |
| " Intrathecal baclofen treatment is a potential treatment option for dystonia and has become common practice." | 5.17 | Intrathecal baclofen treatment in dystonic cerebral palsy: a randomized clinical trial: the IDYS trial. ( Becher, JG; Boeschoten, K; Bonouvrié, LA; de Groot, V; Foncke, E; Geytenbeek, J; Soudant, D; Strijers, R; Teernstra, O; van de Ven, PM; van Ouwerkerk, WJ; Vermeulen, RJ; Vles, JS, 2013) |
| "To measure changes in children with severe spastic cerebral palsy (CP) after continuous intrathecal baclofen (ITB) infusion over 18 months and to compare the results with those of a comparison group awaiting treatment." | 5.15 | Controlled study of the effects of continuous intrathecal baclofen infusion in non-ambulant children with cerebral palsy. ( Gray, N; Morton, RE; Vloeberghs, M, 2011) |
| "8) years, with intractable spastic cerebral palsy were randomised to receive a Synchromed pump for continuous infusion of intrathecal baclofen after either 1 month (CITB group) or 6 months (Control group)." | 5.14 | Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial. ( Becher, JG; Hoving, MA; Palmans, LJ; Spincemaille, GH; van Raak, EP; Vles, JS, 2009) |
| "This study assessed the effects of continuous intrathecal infusion of baclofen on the gait of ambulant children with cerebral palsy." | 5.14 | Intrathecal baclofen infusion for ambulant children with cerebral palsy. ( Brochard, S; Bussel, B; Filipetti, P; Remy-Neris, O, 2009) |
| "Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy." | 5.13 | The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008) |
| "To assess the effectiveness of oral baclofen in reducing spasticity and improving function in children with cerebral palsy." | 5.12 | Oral baclofen in children with cerebral palsy: a double-blind cross-over pilot study. ( Hall, K; Lam, LT; O'Flaherty, S; Scheinberg, A, 2006) |
| "Intrathecal baclofen (ITB) therapy can be very effective in the treatment of intractable spasticity, but its effectiveness and safety have not yet been thoroughly studied in children with cerebral palsy (CP)." | 5.12 | Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study. ( Hoving, MA; Palmans, LJ; Sleypen, FA; Spincemaille, GH; van Raak, EP; Vles, JS, 2007) |
| "Seven children (aged 2-16 years) with dystonia of various aetiologies (dyskinetic cerebral palsy, pantothenate kinase-associated neurodegeneration and Aicardi-Goutières syndrome) underwent transcranial magnetic stimulation, H-reflex and flexor reflex studies before and after intrathecal injection of baclofen." | 5.11 | Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children. ( Dachy, B; Dan, B, 2004) |
| "To describe the efficacy of intrathecal baclofen (ITB) therapy in the management of spasticity in young children with cerebral palsy (CP) and to identify risk factors for complications." | 5.10 | Intrathecal baclofen therapy in children with cerebral palsy: efficacy and complications. ( Hoff, C; Irwin, MC; Murphy, NA, 2002) |
| "The purpose of this article is to describe outcomes of intrathecal baclofen therapy for 29 patients with cerebral palsy, focusing on impairments, functional limitations, and disability." | 5.10 | Functional assessment following intrathecal baclofen therapy in children with spastic cerebral palsy. ( Awaad, R; Awaad, Y; Ham, S; Michon, AM; Munoz, S; Tayem, H, 2003) |
| " This study examines the value of intrathecally administered baclofen in the treatment of 19 children with severe spasticity of cerebral origin: eight of whom sustained brain injury associated with trauma, near drowning, or cardiac arrest; 10 with cerebral palsy (spastic quadriplegia); and one child with Leigh's disease." | 5.08 | Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin. ( Armstrong, RW; Cochrane, DD; Farrell, K; Fife, SE; Kube, SD; Steinbok, P, 1997) |
| "Seventeen patients with congenital spastic cerebral palsy and six patients with other forms of spasticity were injected intrathecally with doses of placebo or baclofen, 25 micrograms, 50 micrograms, or 100 micrograms, in a randomized, double-blind manner." | 5.07 | Intrathecal baclofen for spasticity in cerebral palsy. ( Albright, AL; Cervi, A; Singletary, J, 1991) |
| "A double-blind crossover trial against placebo was conducted to assess the effects of the GABA derivative, baclofen, on the disabilities due to muscle spasticity in twenty children suffering from cerebral palsy." | 5.04 | A controlled trial of baclofen in children with cerebral palsy. ( Jackson, AD; Milla, PJ, 1977) |
| "To investigate the effects of continuous intrathecal baclofen (ITB) therapy in children with cerebral palsy (CP) and other neurological conditions." | 5.01 | Effect of continuous intrathecal baclofen therapy in children: a systematic review. ( Becher, JG; Buizer, AI; Grandbois van Ravenhorst, C; Martens, BHM; Schoonmade, LJ; Vermeulen, RJ, 2019) |
| "Searches included studies with a minimum of five participants with dystonia in CP receiving oral baclofen, benzodiazepines (clonazepam, diazepam, lorazepam), clonidine, gabapentin, levodopa, trihexyphenidyl, botulinum toxin, intrathecal baclofen (ITB), or deep brain stimulation (DBS)." | 4.98 | Pharmacological and neurosurgical interventions for managing dystonia in cerebral palsy: a systematic review. ( Brown, L; Fehlings, D; Harvey, A; Himmelmann, K; Lin, JP; Macintosh, A; Mink, JW; Monbaliu, E; Rice, J; Silver, J; Switzer, L; Walters, I, 2018) |
| "Intrathecal baclofen is an expanding accepted treatment for children with cerebral palsy and other causes of spasticity and dystonia." | 4.98 | Intrathecal Baclofen Therapy-Practical Approach: Clinical Benefits and Complication Management. ( Ben-Pazi, H; Beni-Adani, L; Winter, G, 2018) |
| "To systematically review the effectiveness of oral baclofen versus placebo or other antispastic oral medications in terms of body function, level of activity, and quality of life in children and adolescents with spastic cerebral palsy who are younger than 18 years." | 4.93 | Effectiveness of Oral Baclofen in the Treatment of Spasticity in Children and Adolescents With Cerebral Palsy. ( Gonzalez, W; Nahuelhual, P; Navarrete-Opazo, AA, 2016) |
| "To determine whether intrathecal baclofen is an effective treatment for spasticity in children with cerebral palsy." | 4.91 | Intrathecal baclofen for treating spasticity in children with cerebral palsy. ( Hasnat, MJ; Rice, JE, 2015) |
| "There are 3 surgical procedures that patients with cerebral palsy (CP) undergo that may be considered major procedures: femoral osteotomies combined with pelvic osteotomies, spine fusion, and intrathecal baclofen pump implant for the treatment of spasticity." | 4.90 | Major surgical procedures in children with cerebral palsy. ( DiCindio, S; Theroux, MC, 2014) |
| "Intrathecal baclofen (ITB) is an effective treatment for both spasticity and dystonia in people with cerebral palsy (CP)." | 4.85 | Intrathecal baclofen use in adults with cerebral palsy. ( Krach, LE, 2009) |
| "Pregnancy in patients with intrathecal baclofen (ITB) pumps is rare." | 4.85 | Intrathecal baclofen and pregnancy: implications for clinical care. ( Campbell, C; Delaney, G; DeRibaupierre, S; DeVries-Rizzo, M; Levin, S; Warren, D, 2009) |
| "Intrathecal baclofen (ITB) has become a standard treatment for spasticity in patients with cerebral palsy (CP) over the last ten years." | 4.84 | A review of the complications of intrathecal baclofen in patients with cerebral palsy. ( Kolaski, K; Logan, LR, 2007) |
| "Intrathecal baclofen reduces spasticity in individuals with cerebral palsy." | 4.79 | Intrathecal baclofen in cerebral palsy movement disorders. ( Albright, AL, 1996) |
| " Secondary outcomes included migration percentage (MP), age at TRC closure, previous reconstructive (femoral with/without pelvic osteotomies) surgery, previous intrathecal baclofen, Tönnis osteoarthritis grade, and GMFCS level." | 4.31 | Femoral Head Deformity Associated With Hip Displacement in Nonambulatory Cerebral Palsy: Results at Skeletal Maturity. ( Asma, A; Howard, JJ; Miller, F; Rogers, KJ; Shrader, MW; Ulusaloglu, AC, 2023) |
| "To evaluate the effects of intrathecal baclofen pump (ITBP) therapy on hip dysplasia in young patients with cerebral palsy (CP)." | 4.31 | Does intrathecal baclofen therapy decrease the progression of hip displacement in young patients with cerebral palsy? ( Asma, A; Howard, JJ; McManus, M; Miller, F; Rogers, KJ; Shrader, MW; Ulusaloglu, AC, 2023) |
| "Intrathecal baclofen (ITB) therapy is an effective treatment for spasticity and dystonia in children with cerebral palsy (CP)." | 4.31 | A multicenter initiative to reduce intrathecal baclofen pump surgical site infection: a Cerebral Palsy Research Network quality improvement project. ( Albarqawi, L; Bailes, AF; Bollo, RJ; Browd, SR; Gross, PH; Leonard, JR; Raskin, JS; Rocque, BG, 2023) |
| "This study aimed to determine the risk factors for reconstructive hip surgery after intrathecal baclofen pump application in children with cerebral palsy." | 4.31 | Identification of risk factors for reconstructive hip surgery after intrathecal baclofen therapy in children with cerebral palsy. ( Asma, A; Howard, JJ; Miller, F; Rogers, KJ; Shrader, MW; Ulusaloglu, AC, 2023) |
| "Для поиска статей по теме обзора использовали базу данных PubMed и ключевые слова «cerebral palsy», «spasticity», «dystonia», «selective dorsal rhizotomy», «selective neurotomy», «intrathecal baclofen therapy», «spinal cord stimulation», «deep brain stimulation»." | 4.31 | [Methods and results of neurosurgical treatment of cerebral palsy]. ( Dekopov, AV; Isagulyan, ED; Tomsky, AA, 2023) |
| "The purpose of this study is to describe the efficacy and adverse events of neuraxial anesthesia for post-operative pain control in non-ambulatory children with cerebral palsy with pre-existing intrathecal baclofen (ITB) pumps undergoing hip reconstructive or palliative surgery." | 4.12 | Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps. ( Ball, MA; Davids, JR; Davidson, LT; Kephart, DT; Kulkarni, VA; Tumber, S, 2022) |
| "The purpose of this study was to investigate the incidence of complications in pediatric spastic cerebral palsy (CP) patients weighing less than 20 kg at the time of intrathecal baclofen (ITB) pump implantation and to compare it with spastic CP patients heavier than 20 kg." | 4.12 | Complications of intrathecal baclofen pump treatment in children with spastic cerebral palsy. A comparative analysis of patients weighing over or under 20 kg at the time of implantation. ( Canavese, F; De Coulon, G; Steiger, CN; Tabard-Fougère, A, 2022) |
| "Children with cerebral palsy often suffer from increased tone, which can be treated with intrathecal baclofen via implanted pump." | 4.02 | Epidural catheter placement in children with baclofen pumps. ( Alrayashi, W; Berde, CB; Brusseau, RR; Eklund, SE; Koka, A; Miller, PE; Riley, BL; Samineni, AV; Shore, BJ; Stone, SS, 2021) |
| "This is the first case report describing a laparoscopic fundoplication in a child with an intrathecal Baclofen pump which was inserted because of severe spasticity secondary to cerebral palsy." | 3.96 | Laparoscopic fundoplication for a child with abdominal intrathecal Baclofen pump. ( Aida, Y; Bitoh, Y; Miyauchi, H; Nakatani, T; Okata, Y; Tomioka, Y, 2020) |
| "The purpose of this article is to review the effectiveness of epidural blood patch for the treatment of spinal headache and cerebrospinal fluid leak associated with intrathecal baclofen treatment in children with cerebral palsy." | 3.96 | The effectiveness of epidural blood patch in patients with cerebral palsy treated with intrathecal baclofen implantation. ( Dixit, D; Imerci, A; McManus, M; Miller, F; Rogers, K; Sees, JP, 2020) |
| "In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome." | 3.96 | Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020) |
| "The aim is to study access to intrathecal baclofen (ITB) for children with cerebral palsy (CP) in Europe, as an indicator of access to advanced care." | 3.96 | Access to Intrathecal Baclofen Treatment for Children with Cerebral Palsy in European Countries: An SCPE Survey Reveals Important Differences. ( Andersen, GL; Arnaud, C; de la Cruz, J; Himmelmann, K; Horridge, K; Neubauer, D; Påhlman, M; Rackauskaite, G; Vik, T; Virella, D, 2020) |
| "Insertion of an intrathecal baclofen (ITB) pump can provide significant benefits in patients with cerebral palsy (CP)." | 3.96 | Evaluation of Risk Factors for Cerebrospinal Leakage in Pediatric Patients With Cerebral Palsy Treated With Intrathecal Baclofen. ( Imerci, A; Miller, F; Rogers, KJ; Sees, JP, 2020) |
| "Intrathecal baclofen (ITB) pumps used to manage spasticity in children with cerebral palsy (CP) also improve pain outcomes for some but not all patients." | 3.96 | Investigating the Feasibility of a Modified Quantitative Sensory Testing Approach to Profile Sensory Function and Predict Pain Outcomes Following Intrathecal Baclofen Implant Surgery in Cerebral Palsy. ( Barney, CC; Merbler, AM; Simone, DA; Symons, FJ; Walk, D, 2020) |
| "The effect of a continuous intrathecal infusion of baclofen (CITB) was retrospectively studied in 19 ambulatory children with cerebral palsy (aged 12." | 3.88 | The effect of continuous intrathecal baclofen therapy on ambulatory children with cerebral palsy. ( Church, C; Henley, J; Hulbert, R; Miller, F; Niiler, T; Pruszczynski, B; Sees, J, 2018) |
| "To investigate the effect of intrathecal baclofen (ITB) on function and activity in dyskinetic cerebral palsy (CP)." | 3.88 | Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity. ( Askljung, B; Corneliusson, O; Eek, MN; Himmelmann, K; Lindh, K; Olsson, K; Påhlman, M, 2018) |
| "This article details an unreported potential cause of withdrawal symptoms in a patient with cerebral palsy who experienced intrathecal baclofen withdrawal shortly after placement of a baclofen pump with subsequent refill with Gablofen." | 3.88 | An Unreported Cause of Intrathecal Baclofen Withdrawal Symptoms in a Woman With Spastic Cerebral Palsy Who Received Intrathecal Gablofen. ( Duraski, SA; Sayyad, A, 2018) |
| "Intrathecal baclofen has long been known to be an efficacious treatment of spasticity in children with cerebral palsy." | 3.85 | Lumbar translaminar fenestration for insertion of intrathecal baclofen catheter: a novel technique. ( Al-Shikarchy, H; Chowne, C; Heran, MKS, 2017) |
| "Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps." | 3.85 | Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017) |
| "To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps." | 3.85 | Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017) |
| "OBJECTIVE Medically refractory spasticity and dystonia are often alleviated with intrathecal baclofen (ITB) administration through an indwelling catheter inserted in the lumbar spine." | 3.85 | Image-guided intrathecal baclofen pump catheter implantation: a technical note and case series. ( Berde, C; Dasenbrock, HH; O'Brien, CP; Padua, H; Robertson, FC; Robinson, S, 2017) |
| "Intrathecal baclofen (ITB) therapy for spasticity has been suggested to accelerate the development of scoliosis." | 3.83 | Combined selective dorsal rhizotomy and scoliosis correction procedure in patients with cerebral palsy. ( Ammar, A; Mehdian, H; Moussa, AA; Muquit, S; Nasto, L; Vloeberghs, MH, 2016) |
| "Conventionally, selective dorsal rhizotomy (SDR) has been reserved for ambulant children and implantation of intrathecal baclofen (ITB) pump for non-ambulant children with cerebral palsy." | 3.83 | Selective dorsal rhizotomy as an alternative to intrathecal baclofen pump replacement in GMFCS grades 4 and 5 children. ( Ingale, H; Moussa, AA; Muquit, S; Ughratdar, I; Vloeberghs, MH, 2016) |
| "Intrathecal baclofen (ITB) treatment is applied in patients with spastic cerebral palsy (SCP), dystonic cerebral palsy (DCP) and progressive neurological disease (PND)." | 3.83 | The effect of intrathecal baclofen treatment on activities of daily life in children and young adults with cerebral palsy and progressive neurological disorders. ( Becher, J; Bonouvrié, L; Buizer, A; Soudant, D; van Ouwerkerk, W; Vermeulen, RJ; Vles, G, 2016) |
| "A 15-year-old patient with spastic quadriparesis and cerebral palsy underwent unexpected removal of his baclofen pump due to an infection that was encountered during a planned pump revision." | 3.81 | Dexmedetomidine for acute baclofen withdrawal. ( Heard, CM; Li, V; Morr, S; Reynolds, RM, 2015) |
| "Treatment of severe spasticity and dystonia with intrathecal baclofen (ITB) in children has been shown to be effective and has therefore been employed in the Region of Southern Denmark." | 3.81 | Positive experience with intrathecal baclofen treatment in children with severe cerebral palsy. ( Illum, NO; Kjærsgaard-Hansen, L; Overgård, TM; Søe, M, 2015) |
| "To compare patients with operative cerebral palsy with and without an intrathecal baclofen pump (ITB) to determine whether an ITB increases the complexity of scoliosis surgery and/or increases the risk of wound complications." | 3.81 | Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy. ( Asghar, J; Bastrom, TP; Bomar, JD; Newton, PO; Samdani, AF; Scannell, BP; Shah, SA; Sponseller, PD; Yaszay, B, 2015) |
| "The authors report an unusual case of intrathecal baclofen withdrawal due to the perforation and subsequent leakage of a baclofen pump catheter in a patient with spastic cerebral palsy." | 3.81 | Baclofen pump catheter leakage after migration of the abdominal catheter in a pediatric patient with spasticity. ( Aldana, PR; Dastgir, A; MacGregor, TL; Ranalli, NJ, 2015) |
| "A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion." | 3.81 | Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015) |
| "We describe a 6 year-old girl with hydranencephaly who underwent an intrathecal baclofen test dose and developed severe bradycardia." | 3.81 | Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly. ( Cain, N; Kinsman, S; Sechrist, C, 2015) |
| "Implantation of an intrathecal baclofen pump is recommended for children with cerebral palsy as a means to improve care and comfort when other options fail to control severe hypertonia." | 3.80 | Improvements in children with cerebral palsy following intrathecal baclofen: use of the Rehabilitation Institute of Chicago Care and Comfort Caregiver Questionnaire (RIC CareQ). ( Baker, KW; Gaebler-Spira, D; Mutlu, A; Tann, B, 2014) |
| "To investigate the effect of intrathecal baclofen (ITB) on sitting in children with cerebral palsy with severe spasticity; and identify potential sub-groups of patients at particular risk of deterioration." | 3.80 | The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy. ( Gray, N; Vloeberghs, M, 2014) |
| "This single-center study investigated adverse events that occurred in children and adolescent patients treated with intrathecal baclofen (ITB) therapy for spasticity and/or dystonia." | 3.80 | Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience. ( Antonello, CE; Motta, F, 2014) |
| "Our patient is a 19-year-old girl with cerebral palsy secondary to prematurity and repaired tetralogy of Fallot who had started oral baclofen 8 months before to diminish spasticity." | 3.80 | Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity. ( Hoon, A; Johnston, M; Ogborn, J; Srivastava, S, 2014) |
| "Intrathecal baclofen (ITB) is a reversible treatment that reduces muscle tone to ameliorate spasticity and dystonia in patients with cerebral palsy (CP)." | 3.80 | Indwelling intrathecal catheter with subcutaneous abdominal reservoir: a viable baclofen delivery system in severely cachectic patients. ( Ellenbogen, JR; Kumar, R; Pettorini, BL; Sneade, C; Waqar, M; Williams, D; Zebian, B, 2014) |
| "Intrathecal baclofen treatment (ITB) is widely used in children with cerebral palsy." | 3.79 | Dose-dependent relapse of hiatus hernia after administration of intrathecal baclofen treatment--a rare complication. ( Weber, P, 2013) |
| "Little is known about the long-term effects of Continuous intrathecal Baclofen (CITB) therapy in non-ambulant children with intractable spastic Cerebral Palsy (CP)." | 3.79 | Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy. ( Bonouvrié, LA; Hoving, MA; Soudant, DL; van Oostenbrugge, RJ; Vermeulen, RJ; Vles, GF; Vles, JS, 2013) |
| "A foreign-body reaction after intrathecal baclofen pump implantation is a rare complication, which has not been reported previously, and which is associated with negative skin patch tests." | 3.78 | Intrathecal baclofen pump: a foreign-body reaction case report and its solution. ( Assier, H; Bernuz, B; Bisseriex, H; Rech, C; Schnitzler, A; Thiebaut, JB, 2012) |
| "Intrathecal baclofen therapy has been used successfully for intractable spasticity in children with cerebral palsy." | 3.78 | Evaluation of salvage techniques for infected baclofen pumps in pediatric patients with cerebral palsy. ( Fisher, JF; Hester, SM; Lee, MR; Macomson, S; Vender, JR, 2012) |
| "The aim of this retrospective analysis was to determine the impact of intrathecal baclofen (ITB) therapy on motor function in patients with cerebral palsy (CP)." | 3.77 | Intrathecal baclofen and motor function in cerebral palsy. ( Antonello, CE; Motta, F; Stignani, C, 2011) |
| "Spasticity and dystonia in children with cerebral palsy has been treated with intrathecal baclofen therapy (ITB) at the Royal Children's Hospital, Melbourne, Australia (RCH) since 1999." | 3.77 | Intrathecal baclofen therapy: benefits and complications. ( Antolovich, G; Olesch, C; Reddihough, D; Zdolsek, HA, 2011) |
| "To determine whether intrathecal baclofen (ITB) changes mortality risk in persons with cerebral palsy (CP)." | 3.76 | Survival of individuals with cerebral palsy receiving continuous intrathecal baclofen treatment: a matched-cohort study. ( Day, SM; Krach, LE; Kriel, RL; Strauss, DJ, 2010) |
| "The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy." | 3.76 | Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge? ( Jahnsen, R; Lofterod, B; Ramstad, K; Skjeldal, OH, 2010) |
| "Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy." | 3.76 | Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010) |
| "Baclofen is widely used to control spasticity in children with cerebral palsy." | 3.76 | Long-term oral baclofen treatment in a child with cerebral palsy: electroencephalographic changes and clinical adverse effects. ( De Rinaldis, M; Gennaro, L; Losito, L; Trabacca, A, 2010) |
| "To study the efficacy and safety of intrathecal baclofen therapy (ITB) in wheelchair-dependent adults with cerebral palsy." | 3.76 | Intrathecal baclofen in cerebral palsy. A retrospective study of 25 wheelchair-assisted adults. ( Chenet, A; Ferrapie, AL; Gambart, G; Gay, S; Ménégalli Bogeli, D; Menei, P; Perrouin Verbe, B; Richard, I; Tassëel Ponche, S, 2010) |
| "Prospective studies that address both efficacy and safety of continuous infusion of intrathecal baclofen (CITB) in children with spastic cerebral palsy (CP), and that use outcome measures beyond muscle tone are lacking." | 3.75 | Safety and one-year efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy. ( Gorter, JW; Hoving, MA; Spincemaille, GH; van Kleef, M; van Kranen-Mastenbroek, VH; van Raak, EP; Vles, JS, 2009) |
| " She had previously received an intrathecal baclofen infusion pump to relieve the spasticity of cerebral palsy." | 3.75 | Epidural analgesia in labor for a woman with an intrathecal baclofen pump. ( Ali Sakr Esa, W; Barsoum, S; Tetzlaff, JE; Toma, I, 2009) |
| "To assess the effect of continuous intrathecal baclofen infusion (ITB) on gait parameters of ambulant children with cerebral palsy (CP)." | 3.75 | Changes in gait following continuous intrathecal baclofen infusion in ambulant children and young adults with cerebral palsy. ( Brochard, S; Filipetti, P; Lempereur, M; Rémy-Néris, O, 2009) |
| "Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries." | 3.74 | Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008) |
| "Intrathecal baclofen is used in the management of spasticity associated with cerebral palsy (CP)." | 3.74 | Intravenous diazepam infusion in the management of planned intrathecal baclofen withdrawal. ( Cruikshank, M; Eunson, P, 2007) |
| "Intrathecal baclofen (ITB) is a well-established method of treating spasticity in children with cerebral palsy." | 3.74 | The role of intrathecal baclofen in the management of primary and secondary dystonia in children. ( Tsegaye, M; Vloeberghs, MH; Woon, K, 2007) |
| "A personal case study that looks at the use of Intrathecal Baclofen to relieve the spasticity related to cerebral palsy; improving personal function and enhancing quality of life." | 3.74 | Intrathecal Baclofen: a discussion on impact that medical advances can have on the individual and the implications this has for a society that is built on an ethic of social medicine. ( Baddeley, AA, 2008) |
| "To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort." | 3.74 | The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007) |
| "Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis." | 3.74 | Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007) |
| "In this retrospective study, 20 spastic quadriplegic cerebral palsy (CP) patients with baclofen pumps, who underwent spinal fusion and instrumentation for neuromuscular scoliosis, were matched for weight, age, and type of fusion with patients without pumps." | 3.74 | Outcomes of posterior spinal fusion and instrumentation in patients with continuous intrathecal baclofen infusion pumps. ( Ayyangar, RN; Caird, MS; Drongowski, A; Farley, FA; Garton, H; Hensinger, RN; Palanca, AA, 2008) |
| "The literature available shows that spasticity in patients with cerebral palsy (CP) is reduced by intrathecal baclofen (ITB) treatment, and various studies suggest that this treatment can also be used in dystonic patients." | 3.74 | Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. ( Antonello, CE; Motta, F; Stignani, C, 2008) |
| "In a Dutch national study, we recently established the effectiveness and safety of continuous intrathecal baclofen infusion (CITB) in children with intractable spastic cerebral palsy (CP)." | 3.74 | Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis. ( Ament, AJ; Evers, SM; Hoving, MA; van Raak, EP; Vles, JS, 2008) |
| " At present there are two very promising therapeutic alternatives for patients with infantile cerebral palsy: Botulinum toxin, which we already have a great deal of experience with, and intrathecal treatment with baclofen." | 3.73 | [Intrathecal baclofen and Botulinum toxin in infantile cerebral palsy]. ( Alvarez-Garijo, JA; Barbero, P; Mulas, F; Téllez de Meneses, M, 2005) |
| "The authors evaluated a case series of 5 patients with cerebral palsy and a previously placed subcutaneous reservoir for continuous intrathecal baclofen infusion to control spasticity who underwent spinal arthrodesis with posterior instrumentation for progressive neuromuscular scoliosis deformities." | 3.73 | Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion. ( Kanev, PM; Segal, LS; Wallach, DM, 2005) |
| " We report on an ambulatory patient with a baclofen pump for control of spasticity due to cerebral palsy and dystonia; the patient suffered repeated episodes of catheter migration." | 3.73 | A novel approach to prevent repeated catheter migration in a patient with a baclofen pump: a case report. ( Byers, C; Hall, T; Ross, DA, 2005) |
| "During the 1990s three new techniques to reduce spasticity and dystonia in children with cerebral palsy (CP) were introduced in southern Sweden: selective dorsal rhizotomy, continuous intrathecal baclofen infusion and botulinum toxin treatment." | 3.73 | Prevention of severe contractures might replace multilevel surgery in cerebral palsy: results of a population-based health care programme and new techniques to reduce spasticity. ( Andersson, S; Düppe, H; Hägglund, G; Lauge-Pedersen, H; Nordmark, E; Pedertsen, HL; Westbom, L, 2005) |
| "The objective of this study was to analyze the relationship between epilepsy and intrathecal baclofen by investigating a consecutive sample of 150 children with cerebral palsy or spasticity of cerebral origin who underwent intrathecal baclofen." | 3.73 | Epilepsy and intrathecal baclofen therapy in children with cerebral palsy. ( Buonaguro, V; Curci, D; Iuorno, T; Monforte, S; Motta, F; Scelsa, B, 2005) |
| "Intrathecal baclofen pumps for the management of severe spasticity are being used more often in children with cerebral palsy." | 3.73 | Posterior cervical approach for intrathecal baclofen pump insertion in children with previous spinal fusions. Technical note. ( Liu, JK; Walker, ML, 2005) |
| "Intrathecal baclofen therapy is increasingly used to alleviate medically intractable spasticity in children with cerebral palsy, spinal cord injuries, and generalized dystonia." | 3.73 | Intrathecal baclofen overdose followed by withdrawal: clinical and EEG features. ( Adirim, TA; Darbari, FP; Kothare, SV; Melvin, JJ; Piatt, JH, 2005) |
| "To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy." | 3.73 | Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy. ( Gilpin, P; Jarrett, L; Leary, SM; Lockley, L; Rodriguez, L; Stevenson, VL, 2006) |
| "Intrathecal baclofen (ITB) therapy is being used increasingly to treat medically intractable spasticity in children with cerebral palsy and spinal cord injuries." | 3.73 | Intrathecal baclofen overdose and withdrawal. ( Adirim, TA; Kothare, S; Piatt, JH; Shirley, KW, 2006) |
| "We present a case report on the use of an indium (111) diethylenetriaminepentaacetic acid (DTPA) flow study in the evaluation of a lumbar swelling in a 16-year-old girl with spastic cerebral palsy, treated with continuous intrathecal baclofen (CITB)." | 3.73 | The use of an indium111 DTPA flow study in the evaluation of a lumbar swelling in a girl with a baclofen pump. ( Abdul Fatah, B; Hoving, MA; Smulders, NM; Spincemaille, GH; van Kroonenburgh, MJ; van Raak, EP; Vles, JS, 2006) |
| "To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia." | 3.72 | Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003) |
| " The aim of this paper is to present the result of intrathecal baclofen infusion in treatment of spasticity in patients with cerebral palsy." | 3.72 | [Intrathecal baclofen for treatment of spasticity in patient with cerebral palsy--a preliminary report]. ( Grottel, K; Huber, J; Idzior, M; Jóźwiak, M; Szulc, A, 2003) |
| "Mechanical measures were made in studying six participants with cerebral palsy who were undergoing treatment for spasticity using intrathecal baclofen therapy." | 3.72 | Mechanical measurements of the effects of intrathecal baclofen dosage adjustments in cerebral palsy: a pilot study. ( Gaebler-Spira, D; Schmit, BD, 2004) |
| "The purpose of this study was to assess whether reduction of muscle tone by continuous intrathecal baclofen infusion affects the progression of hip subluxation in persons with cerebral palsy." | 3.72 | Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion. ( Abbott, R; Bloom, KK; Brooks, WH; Gilmartin, RC; Krach, LE; Kriel, RL; Madsen, JR; McLaughlin, JF; Nadell, JM; Storrs, BB; Swift, DM; Ward, JD, 2004) |
| "In this 1-week trial, repetitive administration of baclofen reduced the frequency of emesis and the total number of acid refluxes in neurologically impaired children with GERD." | 3.72 | Effect of baclofen on emesis and 24-hour esophageal pH in neurologically impaired children with gastroesophageal reflux disease. ( Hirayama, S; Ida, S; Kawahara, H; Kawai, M; Yoshimura, N, 2004) |
| "After repair of the catheter of an implanted intrathecal baclofen (ITB) delivery system, a 17-year-old man with cerebral palsy developed acute lower-extremity hypotonia." | 3.71 | Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. ( Murphy, NA, 2002) |
| "To determine if the continuous intrathecal delivery of baclofen will control spastic hypertonia caused by long-standing cerebral palsy (CP)." | 3.71 | Continuously infused intrathecal baclofen over 12 months for spastic hypertonia in adolescents and adults with cerebral palsy. ( Grabb, P; Guin-Renfroe, S; Hadley, MN; Law, C; Meythaler, JM, 2001) |
| "Intrathecal baclofen (ITB) can reduce spasticity in adults and children with cerebral palsy." | 3.71 | Improvement of sleep apnea in a patient with cerebral palsy. ( Gaebler-Spira, D; Harvey, RL; McCarty, SF, 2001) |
| "To determine whether continuous intrathecal baclofen infusion (CIBI) would decrease spasticity and improve function in children with spastic cerebral palsy." | 3.71 | Continuous intrathecal baclofen infusion for children with cerebral palsy: a pilot study. ( Chaseling, R; Dexter, M; O'Flaherty, S; Scheinberg, A, 2001) |
| "We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps." | 3.71 | Reversible coma in children after improper baclofen pump insertion. ( Anderson, KJ; Brown, K; Farmer, JP, 2002) |
| "Dystonia diminished in 10 of 12 patients whose average daily dose of intrathecal baclofen was 575 microg." | 3.70 | Infusion of intrathecal baclofen for generalized dystonia in cerebral palsy. ( Albright, AL; Barry, MJ; Painter, MJ; Shultz, B, 1998) |
| "Intrathecal baclofen infusion (IBI) is an effective treatment for spasticity secondary to cerebral palsy (CP)." | 3.70 | Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy. ( Albright, AL; Gerszten, PC; Johnstone, GF, 1998) |
| "The purpose of the study was to analyze the relative cost of selective functional posterior rhizotomy (SFPR) and continuous intrathecal baclofen in the treatment of children with severe spastic quadriplegia related to cerebral palsy." | 3.69 | Cost analysis of continuous intrathecal baclofen versus selective functional posterior rhizotomy in the treatment of spastic quadriplegia associated with cerebral palsy. ( Daneshvar, H; Evans, D; Kestle, JR; Steinbok, P, 1995) |
| "To test the efficacy of intrathecal baclofen in various movement disorders, 18 patients with dystonia, head trauma, cerebral palsy, rigidity, or painful spasms underwent a trial of intrathecal baclofen." | 3.69 | Intrathecal baclofen for motor disorders. ( Gianino, JM; Penn, RD; York, MM, 1995) |
| "This study was performed to compare the effects of continuous intrathecal baclofen infusion (CIBI) and selective posterior rhizotomy (SPR) on upper extremity (UE) spasticity and range of motion in children with cerebral palsy." | 3.69 | Effects of continuous intrathecal baclofen infusion and selective posterior rhizotomy on upper extremity spasticity. ( Albright, AL; Barry, MJ; Fasick, MP; Janosky, J, 1995) |
| "Five patients with generalized dystonia who were refractory to oral medications were treated by continuous intrathecal baclofen infusion." | 3.69 | Continuous intrathecal baclofen infusion for symptomatic generalized dystonia. ( Albright, AL; Barron, W; Barry, MJ; Fasick, P; Shultz, B, 1996) |
| "Intrathecal baclofen (ITB) infusion has been shown to be an effective treatment for spasticity secondary to both cerebral palsy and spinal cord injury." | 3.69 | Effect on ambulation of continuous intrathecal baclofen infusion. ( Albright, AL; Barry, MJ; Gerszten, PC, 1997) |
| "To determine if continuous intrathecal baclofen infusion (CIBI) would provide continuous relief of spasticity in patients with spasticity of cerebral origin, especially children with cerebral palsy." | 3.68 | Continuous intrathecal baclofen infusion for spasticity of cerebral origin. ( Albright, AL; Barron, WB; Fasick, MP; Janosky, J; Polinko, P, 1993) |
| "This report summarizes experience with baclofen (Lioresal) in the management of spasticity and muscle spasms in 113 patients treated for up to six years." | 3.65 | Bacloffen (Lioresal) in the long-term management of spasticity. ( Jones, RF; Lance, JW, 1976) |
| "Adults with CP and chronic pain receiving usual care had stable, persistent pain intensity." | 3.01 | Clinical course of pain intensity in individuals with cerebral palsy: A prognostic systematic review. ( Côté, P; Fehlings, DL; Hogg-Johnson, S; Shearer, HM; Verville, L, 2023) |
| "For other causes of dystonia, and in particular dystonia due to acquired brain injury, improvements following surgery are more modest and variable." | 3.01 | Neurosurgical management of elevated tone in childhood: interventions, indications and uncertainties. ( Lumsden, DE, 2023) |
| "The causes of spasticity are various and include cerebral palsy, spinal cord injury, stroke, multiple sclerosis or other congenital or acquired lesions of the central nervous system (CNS)." | 3.01 | [Surgical procedures for treatment of spasticity]. ( Daigeler, A; Heinzel, J; Hurth, H; Kolbenschlag, J; Morgalla, M; Schuhmann, M, 2023) |
| "The objective of the present study was to understand the clinical reasons for changes from simple continuous to complex (flex) dosing for tone reduction in individuals receiving intrathecal baclofen." | 2.73 | Complex dosing schedules for continuous intrathecal baclofen infusion. ( Krach, LE; Kriel, RL; Nugent, AC, 2007) |
| "The effects of ITB on spasticity in the upper and lower extremities were evaluated using the Ashworth Scale." | 2.71 | Performance and complications associated with the synchromed 10-ml infusion pump for intrathecal baclofen administration in children. ( Albright, AL; Awaad, Y; Bloom, K; Boydston, WR; Gilmartin, R; Krach, LE; Muhonen, M; Swift, D; Turner, M; Wright, E; Zidek, KA, 2004) |
| "Dystonia was associated with cerebral palsy in 71% of participants." | 2.70 | Intrathecal baclofen for generalized dystonia. ( Albright, AL; Barry, MJ; Ferson, SS; Shafton, DH, 2001) |
| "Eighteen patients with severe spasticity of cerebral origin, who failed to respond adequately to more conservative treatments, have-been treated with continuous infusion of intrathecal baclofen delivered via an implanted pump." | 2.69 | Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients. ( Rawicki, B, 1999) |
| "In 11 patients with spasticity of cerebral origin (mainly cerebral palsy), double-blind scoring of spasticity (Ashworth scale score and visual analog score), spasms, pain, and functional abilities was performed during tests with bolus injections including a placebo control." | 2.69 | Intrathecal baclofen for intractable cerebral spasticity: a prospective placebo-controlled, double-blind study. ( Borghgraef, C; Feys, P; Lagae, L; Nuttin, B; Schrijvers, E; Van Schaeybroeck, P, 2000) |
| "We share our experience of spasticity management with the ITB pump system in five patients at Vilnius University Hospital Santariskiu Klinikos." | 2.55 | Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania. ( Juocevicius, A; Kesiene, J; Kvascevicius, R; Lapteva, O; Mikulenaite, L; Raugalas, R; Rocka, S; Sipylaite, J; Vaitkus, A, 2017) |
| "Because of severe spasticity, many of these patients undergo intrathecal baclofen pump placement before, during, or after posterior spinal fusion." | 2.52 | Scoliosis, spinal fusion, and intrathecal baclofen pump implantation. ( Scannell, B; Yaszay, B, 2015) |
| " Although ITB has been used for more than 20 years clinically, much is still unknown about the most optimal dosing regimens and intrathecal catheter tip placement." | 2.52 | Intrathecal baclofen bolus dosing and catheter tip placement in pediatric tone management. ( Fournier, CM; Skalsky, AJ, 2015) |
| "Pain is one of the most common symptoms in children and young people (CYP) with life-limiting conditions (LLCs) which include a wide range of diagnoses including cancer." | 2.52 | Pharmacological interventions for pain in children and adolescents with life-limiting conditions. ( Beecham, E; Bluebond-Langner, M; Candy, B; Howard, R; Jones, L; Laddie, J; McCulloch, R; Rees, H; Vickerstaff, V, 2015) |
| "These include the management of dystonia and chronic neuropathic pain." | 2.44 | Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain. ( Brennan, PM; Whittle, IR, 2008) |
| "Methods of evaluation of degree of spasticity were also recalled." | 2.44 | [Physical and other methods therapy of the spasticity in children]. ( Jaworek, M; Renata, K; Swierczyńska, A, 2007) |
| "While in some children, spasticity may adversely impact the motor abilities, in others, it may help maintain posture and ability to ambulate." | 2.43 | Pharmacologic interventions for reducing spasticity in cerebral palsy. ( Patel, DR; Soyode, O, 2005) |
| "The management of childhood spasticity requires a multidisciplinary effort." | 2.43 | Management of childhood spasticity: a neurosurgical perspective. ( Anderson, RC; Mandigo, CE, 2006) |
| "The treatment of cerebral palsy is directed at repair of the injured brain and at the management of the impairments and disabilities resulting from developmental brain injury." | 2.42 | The treatment of cerebral palsy: What we know, what we don't know. ( Goldstein, M, 2004) |
| "Cerebral palsy is among the most frequent disorders of the growing locomotor apparatus during childhood." | 2.41 | [Botulinum toxin type A in the treatment plan for cerebral palsy]. ( Strobl, W, 2001) |
| "When excessive spasticity is not sufficiently controlled by physical therapy and pharmacological treatment, patients can have recourse to neurosurgery: neurostimulation, intrathecal baclofen or selective ablative procedures." | 2.41 | Neurosurgery for spasticity. ( Mertens, P; Sindou, MP, 2000) |
| "Baclofen is a muscle relaxant used in both adults and children with neuromuscular disorders to control spasticity." | 2.41 | Baclofen overdose in two siblings. ( Chapple, D; Connors, R; Johnson, D, 2001) |
| "The pathophysiology of spasticity and the history of posterior rhizotomies are reviewed." | 2.38 | Neurosurgical treatment of spasticity: selective posterior rhizotomy and intrathecal baclofen. ( Albright, AL, 1992) |
| "The term cerebral palsy is restricted to non-progressive disorders of motor function, already observed at an early age and due to cerebral lesions." | 2.37 | [Functional neurosurgery of cerebral palsy]. ( Alexandre, F; Angelini, L; Benezech, J; Broggi, G; Claverie, P; Deonna, T; Frerebeau, P; Lazorthes, Y; Siegfried, J; Verdie, JC, 1985) |
| " However, adverse effects, administration, and dosing can be barriers to effectiveness." | 1.91 | Is baclofen the least worst option for spasticity management in children? ( Brandenburg, JE, 2023) |
| "A baclofen intoxication was suspected." | 1.72 | A Severe Baclofen Intoxication Mimicking Post-Hypoxic Encephalopathy: Wait and See! ( Klijn, AJ; Muntinga, L; Noordergraaf, GJ, 2022) |
| "Cerebral palsy is a neurologic disorder characterized by a spectrum of motor and cognitive deficits resulting from insults to the developing brain." | 1.72 | Cerebral Palsy: Current Concepts and Practices in Musculoskeletal Care. ( Cohen, D; Pham, KLD; Sheu, J; Sousa, T, 2022) |
| "Oral medications are often first-line medical management for children with cerebral palsy who have generalised dystonia; however, evidence for their effectiveness is limited and dosing practices are inconsistent." | 1.62 | National surveillance of oral medication prescription for children with dystonic cerebral palsy. ( Antolovich, G; Bear, N; Harvey, A; Rice, J; Waugh, MC, 2021) |
| " The most commonly used ITB dosing modes were continuous (73%) and flexible (23%)." | 1.62 | Intrathecal baclofen pumps in the management of hypertonia in childhood: a UK and Ireland wide survey. ( Amin, S; Ammar, A; Bellis, L; Brink, P; Calisto, A; Crimmins, D; Eunson, P; Forsyth, RJ; Goodden, J; Kaminska, M; Kehoe, J; Kirkpatrick, M; Kumar, R; Leonard, J; Lodh, R; Lording, A; Lumsden, DE; Martin, K; Miller, R; Mordekar, SR; Pettorini, B; Smith, M; Smith, R; Sneade, C; Vloeberghs, M; Whitney, A; Zaki, H, 2021) |
| "The aim of the study was to identify oral baclofen dosing variability at steady state based on weight and Gross Motor Function Classification System level using a retrospective cross-sectional study design." | 1.56 | Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy. ( McGhee, E; McLaughlin, MJ; Ratnasingam, D, 2020) |
| "Arginineemia, also known as arginase deficiency, is a rare autosomal recessive metabolic disease." | 1.56 | A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report. ( Cao, L; Cui, D; Hu, L; Jin, L; Liu, Y, 2020) |
| "Isolated dystonia or spasticity was infrequently seen, with a mixed picture of dystonia and spasticity ± choreoathetosis identified in 194/275 (70." | 1.51 | Pharmacological management of abnormal tone and movement in cerebral palsy. ( Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M, 2019) |
| "The two groups will be matched for spasticity and other important clinical characteristics at baseline." | 1.51 | Comparing the effects of two spasticity management strategies on the long-term outcomes of individuals with bilateral spastic cerebral palsy: a multicentre cohort study protocol. ( Chen, BP; MacWilliams, BA; McMulkin, ML; Munger, ME; Schwartz, MH, 2019) |
| "Oral baclofen was used by all doctors and was the first choice of 10 of 11." | 1.48 | Oral medication prescription practices of tertiary-based specialists for dystonia in children with cerebral palsy. ( Harvey, A; Reddihough, D; Scheinberg, A; Williams, K, 2018) |
| " The Specialized Health Needs Interagency Collaboration (SHNIC) program at the Kennedy Krieger Institute has complied education and materials that explain the use of baclofen pumps in children with spasticity and the role of the school nurse in providing staff training, developing emergency care plans, and creating a safe school environment for children with special health needs." | 1.48 | Hidden Medical Devices in the School Setting: What the School Nurse Needs to Know About the Safe Use of Baclofen Pumps. ( Obst, B; Roesler, M, 2018) |
| "Patient characteristics, spasticity scores pre/post intrathecal baclofen test dose, and IDDS perioperative implantation records were collected." | 1.48 | Title: Quantifying the change of spasticity after intrathecal baclofen administration: A descriptive retrospective analysis. ( Beck, LA; Bendel, MA; Hoelzer, BC; Lueders, DR; Pingree, MJ; Pittelkow, TP, 2018) |
| "Children with cerebral palsy experience spasticity that can be debilitating and cause significant pain and contractures." | 1.46 | Nurse Practitioner Lead Pediatric Baclofen Pump Program: Impact on Safety and Quality of Care. ( Buxton, K; Morgan, A; Rogers, J, 2017) |
| "Change of spasticity was evaluated using the Modified Ashworth Scale." | 1.46 | Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury. ( Chae, M; Chang, JW; Chang, WS; Cho, HE; Cho, SR; Lee, KC; Yoon, YK, 2017) |
| " Following botulinum toxin A treatment, clinical improvement led to the gradual reduction of baclofen or tizanidine dosing to one-third of the former dose." | 1.43 | Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity. ( Aksoy, SN; Dai, AI; Demiryürek, AT, 2016) |
| "To examine dosing patterns in patients receiving baclofen via intrathecal baclofen pumps to assess for common patterns by diagnosis, ambulation ability, and affected limbs distribution." | 1.43 | Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review. ( Clearfield, JS; McGuire, J; Nelson, ME; Rein, LE; Tarima, S, 2016) |
| "All children are known to have severe dyskinetic cerebral palsy and presented with an acute or sub-acute deterioration in their symptoms." | 1.43 | Status dystonicus in children: Early recognition and treatment prevent serious complications. ( Abu-Arafeh, I; Combe, L, 2016) |
| "To assess the frequency and types of adverse events (AEs) related to intrathecal baclofen (ITB) therapy in adults, and associated risk factors." | 1.40 | Occurrence of adverse events in long-term intrathecal baclofen infusion: a 1-year follow-up study of 158 adults. ( Bensmail, D; Borrini, L; Hugeron, C; Jourdan, C; Rech, C; Thiebaut, JB, 2014) |
| "Our experience shows that low cervical catheter insertion for administration of a test dose of intrathecal baclofen and feasible and safe to perform via the method described." | 1.38 | Cervical catheter placement for intrathecal baclofen test dose: is it safe? ( Ingale, H; Muquit, S; Ughratdar, I; Vloeberghs, M, 2012) |
| "Spasticity is the major etiology for hip dislocation in nonambulatory cerebral palsy patients." | 1.38 | A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients. ( Ayyangar, RN; Caird, MS; Craig, CL; Farley, FA; Hensinger, RN; Hurvitz, EA; Nowicki, P; Silva, S; Vanderhave, KL, 2012) |
| "There are few reports of spasticity treatment for people with ID, and none of functionally meaningful outcomes." | 1.36 | Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability. ( Ayers, GD; Blair, CR; Charles, PD; Gill, CE; Konrad, PE; Putman, MS; Roberts, AG; Taylor, HM, 2010) |
| "A 12-year-old girl suffering from spastic diplegia was implanted with a Medtronic SynchroMed II pump (Medtronic Inc." | 1.36 | Malfunction of SynchroMed II baclofen pump delivers a near-lethal baclofen overdose. ( Charalambides, C; Kostopanagiotou, G; Matsota, P; Sgouros, S; Tsangaris, I, 2010) |
| " There are few published guidelines for dosing efficacy and no studies looking at the effect of concentration of ITB on spasticity management." | 1.35 | Effect of intrathecal baclofen concentration on spasticity control: case series. ( Chiodo, AE; Saval, A, 2008) |
| "An 11-year-old boy with spasticity and apallic syndrome needed general anesthesia for exchange of a baclofen pump but 2 h later he became increasingly hypothermic, hypotonic with bradycardy and dyspnea." | 1.35 | [Intrathecal baclofen therapy. Overdose during replacement of a medication pump]. ( Koulousakis, A; Kramer, K; Krep, H; Lier, H; Weber, M, 2009) |
| "Patients with spastic quadriplegia secondary to cerebral palsy manifest with severe spasticity and often with neuromuscular scoliosis." | 1.35 | Concomitant correction of spinal deformity and spasticity management with posterior instrumentation and baclofen pump implantation. ( Cabrera, MN; Lai, LP; Shilt, JS; Snow, SB, 2009) |
| "Although spasticity is a common symptom in children with cerebral palsy, weakness may be a much greater contributor to disability." | 1.35 | Oral baclofen increases maximal voluntary neuromuscular activation of ankle plantar flexors in children with spasticity due to cerebral palsy. ( Kukke, S; McGill, K; Rose, J; Sanger, TD; Sherman-Levine, S; van Doornik, J, 2008) |
| "In children, spasticity is commonly seen in the context of cerebral palsy (CP), but also following head injury, cerebral infarct or other brain insults." | 1.34 | Surgical management of spasticity of cerebral origin in children. ( Sgouros, S, 2007) |
| "Treatment of spasticity with intrathecal baclofen pump implantation is a chance for clinical improvement in patients with severe spasticity." | 1.34 | [The parents expectations after baclofen pump implantation in child with severe spasticity in physical rehabilitation and psychological aspects]. ( Fafara, A; Grzegorzewski, P; Kawecka, J; Kawecki, Z; Kwiatkowski, S, 2007) |
| "The baclofen pump has been utilized in children with refractory spasticity." | 1.33 | Placement of baclofen pumps through the foramen magnum and upper cervical spine. ( Dziurzynski, K; Iskandar, BJ; Mcleish, D; Ward, M, 2006) |
| "Although excessive weight gain is not a common problem in children with cerebral origin spasticity, increased weight-gain velocity is prevalent in children receiving ITB therapy." | 1.33 | Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy. ( Ayyangar, RN; Fox, MA; McCoy, AA; Schaubel, DE, 2006) |
| " Secondary objectives included determining correlations between dosage and age, injury type, location of spasticity, comorbid seizures, or concomitant antispasticity medications." | 1.33 | Oral baclofen and clonidine for treatment of spasticity in children. ( Haase, M; Habersang, R; Lubsch, L; Luedtke, S, 2006) |
| "Thirty children with spasticity of cerebral origin receiving ITB therapy." | 1.32 | Oral motor, communication, and nutritional status of children during intrathecal baclofen therapy: a descriptive pilot study. ( Bader, KA; Bjornson, KF; Desmond, SA; Loeser, JD; McLaughlin, JF; Nowak-Cooperman, KM; Russel, M, 2003) |
| "After several reports of new-onset seizures in children treated with oral baclofen at our institution, we reviewed our experience regarding possible effects of baclofen on seizure induction in a childhood movement disorders program over a 2-year period." | 1.32 | Oral baclofen in cerebral palsy: possible seizure potentiation? ( Hansel, CR; Hansel, DE; Hoon, AH; Johnston, MV; Levey, EB; Madden, L; Reinhardt, EM; Shindle, MK, 2003) |
| "To ascertain the prevalence of spasticity among adults living in a developmental center and to document the development of spasticity treatment plans for this population." | 1.32 | Spasticity in adults living in a developmental center. ( Charles, PD; Damian, MM; Noel-Spaudling, S; Pfister, AA; Roberts, AG; Taylor, HM, 2003) |
| " The average dosage for the total group was 463 micrograms per day (microg/day), and 32% used a simple infusion mode." | 1.32 | Intrathecal baclofen therapy over 10 years. ( Rawlins, PK, 2004) |
| " During 80 recipient-years of pump operation, 153 treatment-associated adverse events occurred: 27 of these were device-related." | 1.31 | Long-term safety and efficacy of continuous intrathecal baclofen. ( Bjornson, K; Campbell, WM; Ferrel, A; Grant, GA; Graubert, C; Loeser, JD; McLaughlin, JF, 2002) |
| "Oral baclofen improves cerebral spasticity mildly, but its activity is limited because of its poor lipid solubility." | 1.29 | Baclofen in the treatment of cerebral palsy. ( Albright, AL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (1.75) | 18.7374 |
| 1990's | 30 (10.49) | 18.2507 |
| 2000's | 107 (37.41) | 29.6817 |
| 2010's | 95 (33.22) | 24.3611 |
| 2020's | 49 (17.13) | 2.80 |
| Authors | Studies |
|---|---|
| Samineni, AV | 2 |
| Eklund, SE | 2 |
| Miller, PE | 2 |
| Buxton, K | 2 |
| Snyder, BD | 1 |
| Matheney, TH | 1 |
| Watkins, CJ | 1 |
| Stone, SSD | 1 |
| Alrayashi, W | 2 |
| Brusseau, R | 1 |
| Shore, BJ | 2 |
| Muntinga, L | 1 |
| Klijn, AJ | 1 |
| Noordergraaf, GJ | 1 |
| Kulkarni, VA | 1 |
| Kephart, DT | 1 |
| Ball, MA | 1 |
| Tumber, S | 1 |
| Davidson, LT | 1 |
| Davids, JR | 1 |
| Bonouvrié, LA | 5 |
| Haberfehlner, H | 2 |
| Becher, JG | 6 |
| Vles, JSH | 2 |
| Vermeulen, RJ | 7 |
| Buizer, AI | 4 |
| Shearer, HM | 1 |
| Verville, L | 1 |
| Côté, P | 1 |
| Hogg-Johnson, S | 1 |
| Fehlings, DL | 1 |
| Kakodkar, P | 1 |
| Girgis, H | 1 |
| Nabhan, P | 1 |
| Chee, SS | 1 |
| Tu, A | 2 |
| Sheu, J | 1 |
| Cohen, D | 1 |
| Sousa, T | 1 |
| Pham, KLD | 1 |
| Ulusaloglu, AC | 3 |
| Asma, A | 3 |
| Rogers, KJ | 4 |
| Shrader, MW | 4 |
| Miller, F | 8 |
| Howard, JJ | 4 |
| Ronchetti, AB | 1 |
| Bertamino, M | 1 |
| Tacchino, CM | 1 |
| Moretti, P | 1 |
| Pavanello, M | 1 |
| McManus, M | 2 |
| Lumsden, DE | 3 |
| Bollo, RJ | 1 |
| Gross, PH | 1 |
| Rocque, BG | 1 |
| Browd, SR | 1 |
| Raskin, JS | 1 |
| Leonard, JR | 1 |
| Albarqawi, L | 1 |
| Bailes, AF | 1 |
| McLaughlin, MJ | 3 |
| Fisher, MT | 1 |
| De Rinaldis, M | 2 |
| Gallo, I | 1 |
| Oliva, MC | 1 |
| Trabacca, A | 2 |
| Brandenburg, JE | 1 |
| Srinivasan, R | 1 |
| Cobourn, KD | 1 |
| Patel, N | 1 |
| Tsering, D | 1 |
| Jamshidi, AM | 1 |
| Abousy, M | 1 |
| Myseros, JS | 1 |
| Oluigbo, C | 1 |
| Magge, SN | 1 |
| Keating, RF | 1 |
| Gormley, M | 1 |
| Dekopov, AV | 2 |
| Tomsky, AA | 1 |
| Isagulyan, ED | 1 |
| Albright, AL | 16 |
| Assumpcao de Monaco, B | 1 |
| Fruett da Costa, PR | 1 |
| Franceschini, PR | 1 |
| Hurth, H | 1 |
| Morgalla, M | 1 |
| Heinzel, J | 1 |
| Daigeler, A | 1 |
| Kolbenschlag, J | 1 |
| Schuhmann, M | 1 |
| Hagemann, C | 1 |
| Schmitt, I | 1 |
| Lischetzki, G | 1 |
| Kunkel, P | 1 |
| Okata, Y | 1 |
| Bitoh, Y | 1 |
| Aida, Y | 1 |
| Miyauchi, H | 1 |
| Nakatani, T | 1 |
| Tomioka, Y | 1 |
| Ratnasingam, D | 1 |
| McGhee, E | 1 |
| Thomas, SP | 1 |
| Addison, AP | 1 |
| Curry, DJ | 1 |
| Boeschoten, K | 2 |
| Fleuren, S | 1 |
| Monbaliu, E | 2 |
| Imerci, A | 2 |
| Rogers, K | 1 |
| Dixit, D | 1 |
| Sees, JP | 2 |
| Lins, LAB | 1 |
| Nechyporenko, AV | 1 |
| Halanski, MA | 2 |
| Hetzel, SJ | 1 |
| Noonan, KJ | 2 |
| Himmelmann, K | 3 |
| Påhlman, M | 2 |
| Andersen, GL | 3 |
| Vik, T | 2 |
| Virella, D | 1 |
| Horridge, K | 1 |
| Neubauer, D | 1 |
| Arnaud, C | 1 |
| Rackauskaite, G | 1 |
| de la Cruz, J | 1 |
| Stewart, K | 2 |
| Copeland, L | 1 |
| Lewis, J | 1 |
| Saenz, A | 1 |
| Grijalba, M | 1 |
| Mengide, JP | 1 |
| Argañaraz, R | 1 |
| Ford, F | 1 |
| Mantese, B | 1 |
| Steinbok, P | 5 |
| Mohon, RT | 2 |
| Khan, E | 1 |
| DelRosso, LM | 2 |
| Cui, D | 1 |
| Liu, Y | 1 |
| Jin, L | 1 |
| Hu, L | 1 |
| Cao, L | 1 |
| Koka, A | 1 |
| Riley, BL | 1 |
| Brusseau, RR | 1 |
| Stone, SS | 1 |
| Berde, CB | 1 |
| Tabard-Fougère, A | 1 |
| Canavese, F | 1 |
| Steiger, CN | 1 |
| De Coulon, G | 1 |
| Harvey, A | 3 |
| Bear, N | 1 |
| Rice, J | 2 |
| Antolovich, G | 2 |
| Waugh, MC | 1 |
| Bohn, E | 1 |
| Goren, K | 1 |
| Switzer, L | 2 |
| Falck-Ytter, Y | 1 |
| Fehlings, D | 2 |
| Gburek-Augustat, J | 1 |
| Krause, M | 1 |
| Bernhard, M | 1 |
| Sorge, I | 1 |
| Gräfe, D | 1 |
| Siekmeyer, M | 1 |
| Nestler, U | 1 |
| Merkenschlager, A | 1 |
| Lodh, R | 2 |
| Amin, S | 2 |
| Ammar, A | 3 |
| Bellis, L | 1 |
| Brink, P | 1 |
| Calisto, A | 1 |
| Crimmins, D | 1 |
| Eunson, P | 3 |
| Forsyth, RJ | 1 |
| Goodden, J | 1 |
| Kaminska, M | 1 |
| Kehoe, J | 1 |
| Kirkpatrick, M | 1 |
| Kumar, R | 3 |
| Leonard, J | 1 |
| Lording, A | 1 |
| Martin, K | 1 |
| Miller, R | 1 |
| Mordekar, SR | 2 |
| Pettorini, B | 1 |
| Smith, M | 2 |
| Smith, R | 1 |
| Sneade, C | 2 |
| Whitney, A | 1 |
| Vloeberghs, M | 4 |
| Zaki, H | 1 |
| Kudva, A | 1 |
| Abraham, ME | 1 |
| Gold, J | 1 |
| Patel, NA | 1 |
| Gendreau, JL | 1 |
| Herschman, Y | 1 |
| Mammis, A | 1 |
| Dallas, J | 1 |
| Naftel, RP | 1 |
| Shannon, CN | 1 |
| Sawyer, K | 1 |
| Pickett, K | 1 |
| Bothwell, S | 1 |
| Brinton, JT | 1 |
| Sobremonte-King, M | 1 |
| Hägglund, G | 2 |
| Hollung, SJ | 2 |
| Ahonen, M | 1 |
| Eggertsdóttir, G | 1 |
| Gaston, MS | 1 |
| Jahnsen, R | 2 |
| Jeglinsky-Kankainen, I | 1 |
| Nordbye-Nielsen, K | 1 |
| Tresoldi, I | 1 |
| Alriksson-Schmidt, AI | 1 |
| Heran, MKS | 1 |
| Al-Shikarchy, H | 1 |
| Chowne, C | 1 |
| Pruszczynski, B | 1 |
| Sees, J | 1 |
| Hulbert, R | 1 |
| Church, C | 1 |
| Henley, J | 1 |
| Niiler, T | 1 |
| Morgan, A | 1 |
| Rogers, J | 1 |
| Yoon, YK | 1 |
| Lee, KC | 1 |
| Cho, HE | 1 |
| Chae, M | 1 |
| Chang, JW | 2 |
| Chang, WS | 2 |
| Cho, SR | 2 |
| He, Y | 2 |
| Brunstrom-Hernandez, J | 1 |
| Thio, LL | 2 |
| Carleton, BC | 1 |
| Ross, CJD | 1 |
| Gaedigk, A | 2 |
| Lewandowski, A | 2 |
| Dai, H | 2 |
| Jusko, WJ | 2 |
| Leeder, JS | 2 |
| Walker, KR | 1 |
| Novotny, SA | 1 |
| Krach, LE | 9 |
| Reddihough, D | 2 |
| Scheinberg, A | 5 |
| Williams, K | 1 |
| Weinstein, SM | 1 |
| McLaughlin, M | 1 |
| Eek, MN | 1 |
| Olsson, K | 1 |
| Lindh, K | 1 |
| Askljung, B | 1 |
| Corneliusson, O | 1 |
| Liew, PY | 1 |
| Khan, D | 1 |
| Arnup, SJ | 1 |
| Obst, B | 1 |
| Roesler, M | 1 |
| Aljuboori, Z | 1 |
| Archer, J | 1 |
| Huff, W | 1 |
| Moreno, A | 1 |
| Jea, A | 1 |
| Brown, L | 1 |
| Lin, JP | 1 |
| Macintosh, A | 1 |
| Mink, JW | 1 |
| Silver, J | 1 |
| Walters, I | 1 |
| Duraski, SA | 1 |
| Sayyad, A | 1 |
| Pittelkow, TP | 1 |
| Bendel, MA | 1 |
| Lueders, DR | 1 |
| Beck, LA | 1 |
| Pingree, MJ | 1 |
| Hoelzer, BC | 1 |
| Winter, G | 1 |
| Beni-Adani, L | 1 |
| Ben-Pazi, H | 1 |
| Martens, BHM | 1 |
| Grandbois van Ravenhorst, C | 1 |
| Schoonmade, LJ | 1 |
| Kim, JH | 1 |
| Jung, NY | 1 |
| Jung, HH | 1 |
| So, PNH | 1 |
| Castañeda, MRRQ | 1 |
| Morante, ARV | 1 |
| Oliva, RV | 1 |
| Crowe, B | 1 |
| Basu, A | 1 |
| Devlin, A | 1 |
| DeAlwis, Y | 1 |
| Lundy, CT | 1 |
| Cadwgan, J | 1 |
| Ross Raftemo, AE | 1 |
| Mahendran, A | 1 |
| Jahnsen, RB | 1 |
| Lydersen, S | 1 |
| Munger, ME | 1 |
| Chen, BP | 1 |
| MacWilliams, BA | 1 |
| McMulkin, ML | 1 |
| Schwartz, MH | 1 |
| Barney, CC | 1 |
| Merbler, AM | 1 |
| Simone, DA | 1 |
| Walk, D | 1 |
| Symons, FJ | 1 |
| Baker, KW | 1 |
| Tann, B | 1 |
| Mutlu, A | 1 |
| Gaebler-Spira, D | 4 |
| Weber, P | 1 |
| Vles, GF | 1 |
| Soudant, DL | 1 |
| Hoving, MA | 6 |
| van Oostenbrugge, RJ | 1 |
| Vles, JS | 7 |
| Faulkner, SD | 1 |
| Ruff, CA | 1 |
| Fehlings, MG | 1 |
| Gray, N | 2 |
| Soudant, D | 2 |
| de Groot, V | 1 |
| van Ouwerkerk, WJ | 1 |
| Strijers, R | 1 |
| Foncke, E | 1 |
| Geytenbeek, J | 1 |
| van de Ven, PM | 1 |
| Teernstra, O | 1 |
| Motta, F | 5 |
| Antonello, CE | 3 |
| Borrini, L | 1 |
| Bensmail, D | 1 |
| Thiebaut, JB | 2 |
| Hugeron, C | 1 |
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| Jourdan, C | 1 |
| Theroux, MC | 1 |
| DiCindio, S | 1 |
| Stroud, J | 1 |
| Scattoloni, J | 1 |
| Blasingim, M | 1 |
| Nafiu, OO | 1 |
| Brunstrom-Hernandez, JE | 1 |
| Lackey, S | 1 |
| Kuroda, MM | 1 |
| Stashinko, E | 1 |
| Hoon, AH | 2 |
| Vargus-Adams, J | 1 |
| Stevenson, RD | 1 |
| Lowenhaupt, S | 1 |
| McLaughlin, JF | 5 |
| Christensen, A | 1 |
| Dosa, NP | 1 |
| Butler, M | 1 |
| Schwabe, A | 1 |
| Lopez, C | 1 |
| Roge, D | 1 |
| Kennedy, D | 1 |
| Tilton, A | 1 |
| Gooch, JL | 3 |
| McFadden, M | 1 |
| Oberg, W | 1 |
| Gunnarsson, S | 1 |
| Samuelsson, K | 1 |
| Srivastava, S | 1 |
| Hoon, A | 1 |
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| Johnston, M | 1 |
| Waqar, M | 1 |
| Ellenbogen, JR | 1 |
| Zebian, B | 1 |
| Williams, D | 1 |
| Pettorini, BL | 1 |
| Morr, S | 1 |
| Heard, CM | 1 |
| Li, V | 1 |
| Reynolds, RM | 1 |
| Rush, R | 1 |
| Kumbhare, D | 1 |
| Scannell, B | 1 |
| Yaszay, B | 2 |
| Skalsky, AJ | 1 |
| Fournier, CM | 1 |
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| Overgård, TM | 1 |
| Kjærsgaard-Hansen, L | 1 |
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| Ingale, H | 2 |
| Ughratdar, I | 2 |
| Hasnat, MJ | 1 |
| Rice, JE | 1 |
| Bonouvrié, L | 1 |
| Becher, J | 1 |
| Buizer, A | 1 |
| van Ouwerkerk, W | 1 |
| Vles, G | 1 |
| Rushton, PRP | 1 |
| Nasto, LA | 1 |
| Aujla, RK | 1 |
| Grevitt, MP | 1 |
| Mietton, C | 1 |
| Nuti, C | 1 |
| Dohin, B | 1 |
| Bayle, B | 1 |
| Fernandez, B | 1 |
| Poirot, I | 1 |
| Gautheron, V | 1 |
| Vuillerot, C | 1 |
| Combe, L | 1 |
| Abu-Arafeh, I | 1 |
| Kvascevicius, R | 1 |
| Lapteva, O | 1 |
| Kesiene, J | 1 |
| Vaitkus, A | 1 |
| Mikulenaite, L | 1 |
| Raugalas, R | 1 |
| Sipylaite, J | 1 |
| Rocka, S | 1 |
| Juocevicius, A | 1 |
| Agarwal, S | 1 |
| Patel, T | 1 |
| Shah, N | 1 |
| Patel, BM | 1 |
| Morishita, A | 1 |
| Aihara, H | 1 |
| Nakai, T | 1 |
| Adachi, M | 1 |
| Robinson, S | 1 |
| Robertson, FC | 1 |
| Dasenbrock, HH | 1 |
| O'Brien, CP | 1 |
| Berde, C | 1 |
| Padua, H | 1 |
| Kraus, T | 1 |
| Gegenleitner, K | 1 |
| Svehlik, M | 1 |
| Novak, M | 1 |
| Steinwender, G | 1 |
| Singer, G | 1 |
| van Raak, EP | 5 |
| Spincemaille, GH | 4 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pediatric Pharmacokinetic and Pharmacodynamic Study of Oral Baclofen for the Treatment of Spasticity Associated With Cerebral Palsy[NCT00607542] | Phase 1/Phase 2 | 61 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
| Movement Impairment Characterization and Rehabilitation for Spastic/Dystonic Cerebral Palsy Using Robotic Haptic Feedback in Virtual Reality[NCT03744884] | 68 participants (Anticipated) | Interventional | 2018-12-01 | Recruiting | |||
| Long-term Outcomes of Selective Dorsal Rhizotomy Among Individuals With Cerebral Palsy Compared to a Matched Control Group[NCT03789786] | 78 participants (Actual) | Observational | 2018-11-01 | Completed | |||
| Chronic Postsurgical Pain in Cerebral Palsy[NCT05764681] | 500 participants (Anticipated) | Observational | 2023-03-31 | Not yet recruiting | |||
| Neural Operant Conditioning to Improve Walking After Stroke[NCT06113965] | 60 participants (Anticipated) | Interventional | 2024-05-31 | Recruiting | |||
| Pros and Cons of Botulinum Injection Treatment in Cerebral Palsy: A Qualitative Study Examining the Caregiver's Perspectives[NCT04256187] | 21 participants (Actual) | Observational | 2019-11-01 | Completed | |||
| Inter-Rater Reliability of a Spasticity Diagnosis Algorithm[NCT01644123] | 72 participants (Actual) | Observational | 2013-04-30 | Completed | |||
| Using Telemedicine to Improve Spasticity Diagnosis Rates[NCT03211390] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility[NCT03250988] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity[NCT03209960] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| Intrathecal (IT) Baclofen Drug Distribution Pilot Study[NCT02903823] | Phase 4 | 27 participants (Actual) | Interventional | 2016-04-22 | Completed | ||
| A Randomized, Placebo Controlled Trial of Botulinum Toxin for Paratonic Rigidity in People With Advanced Cognitive Impairment[NCT02212119] | Phase 2 | 10 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| Multi Center Project: Comparison of Functional Outcomes of Tendon Transfer Surgery, Botulinum Toxin Injections and Regular Ongoing Treatment in Hemiplegic Upper Extremity Cerebral Palsy[NCT00250081] | 38 participants (Actual) | Interventional | 2005-02-28 | Terminated (stopped due to Accrual is complete.) | |||
| A Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Incobotulinumtoxin Type A for the Functional Improvement of Lower Extremity Spasticity in Patients With Multiple Sclerosis[NCT01968902] | Phase 4 | 27 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Intrathecal Baclofen. Evaluation of a Therapy for Refractory Spasticity in Children With Cerebral Palsy[NCT00367068] | Phase 3 | 18 participants | Interventional | 2002-01-31 | Completed | ||
| The Clinical Effect and Sonographic Findings of Kinesiotaping Combined With Therapeutic Exercise in Upper Extremity Spasticity and Function in Subacute Stroke Patients[NCT03024190] | 36 participants (Actual) | Interventional | 2017-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The Modified Ashworth Scale (MAS) is a 6-point scale (Standard MAS scale values: 0, 1, 1.5, 2, 3, or 4) used to evaluate spasticity based on grading muscle tone by moving joints. The MAS scores in this cohort are measured in biceps, triceps and forearm flexor muscles in upper extremities; and quadriceps, hamstrings and gastrocnemius muscles in lower extremities. The score ranges from 0 (no increase in muscle tone) to 4 (affected part(s) rigid in flexion or extension). Improvement in spasticity was a reduction in MAS score by 1 point across a joint tested. Maximal MAS change is the sum of MAS score reduction in all four limbs tested.~This outcome looks at subjects with spasticity of cerebral origin." (NCT02903823)
Timeframe: Baseline to 6 hours post-injection
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Cervical level 4 injection site | Thoracic level 3 injection site | Thoracic level 10 injection site | Lumbar lever 2 injection site | |
| Subjects With Max MAS Change | 8 | 7 | 3 | 3 |
"The Modified Ashworth Scale (MAS) is a 6-point scale (Standard MAS scale values: 0, 1, 1.5, 2, 3, or 4) used to evaluate spasticity based on grading muscle tone by moving joints. The MAS scores in this cohort are measured in biceps, triceps and forearm flexor muscles in upper extremities; and quadriceps, hamstrings and gastrocnemius muscles in lower extremities. The score ranges from 0 (no increase in muscle tone) to 4 (affected part(s) rigid in flexion or extension). Improvement in spasticity was a reduction in MAS score by 1 point across a joint tested. Maximal MAS change is the sum of MAS score reduction in all four limbs tested.~This outcome looks at subjects with spasticity of spinal origin." (NCT02903823)
Timeframe: Baseline to 6 hours post-injection
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Cervical spine level 4 injection site | Thoracic level 3 injection site | Thoracic level 10 injection site | Lumbar level 2 injection site | |
| Subjects With MAS Change - Based on Site of Injection | 4 | 2 | 5 | 3 |
49 reviews available for baclofen and Cerebral Palsy
| Article | Year |
|---|---|
Clinical course of pain intensity in individuals with cerebral palsy: A prognostic systematic review.
Topics: Adult; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Chronic Pain; Humans; Pain Measure | 2023 |
Neurosurgical management of elevated tone in childhood: interventions, indications and uncertainties.
Topics: Baclofen; Cerebral Palsy; Child; Dystonia; Humans; Muscle Relaxants, Central; Muscle Spasticity; Rhi | 2023 |
Spasticity and movement disorders in cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Dystonia; Humans; Movement Disorders; Muscle Relaxants, Central; Mu | 2023 |
[Surgical procedures for treatment of spasticity].
Topics: Baclofen; Cerebral Palsy; Child; Humans; Muscle Spasticity; Quality of Life; Rhizotomy | 2023 |
Surgical Tone Reduction in Cerebral Palsy.
Topics: Baclofen; Cerebral Palsy; Deep Brain Stimulation; Dystonia; Humans; Injections, Spinal; Muscle Relax | 2020 |
Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta-analysis.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Clonidine; Deep Brain Stimulation; Dystonia; Humans; Inj | 2021 |
Intrathecal baclofen, selective dorsal rhizotomy, and extracorporeal shockwave therapy for the treatment of spasticity in cerebral palsy: a systematic review.
Topics: Baclofen; Cerebral Palsy; Child; Extracorporeal Shockwave Therapy; Humans; Muscle Relaxants, Central | 2021 |
Pharmacological and neurosurgical interventions for managing dystonia in cerebral palsy: a systematic review.
Topics: Baclofen; Cerebral Palsy; Deep Brain Stimulation; Dystonia; Humans; Muscle Relaxants, Central; Neuro | 2018 |
Intrathecal Baclofen Therapy-Practical Approach: Clinical Benefits and Complication Management.
Topics: Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity | 2018 |
Effect of continuous intrathecal baclofen therapy in children: a systematic review.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; GABA-B Receptor Agonists; Humans; | 2019 |
The potential for stem cells in cerebral palsy--piecing together the puzzle.
Topics: Baclofen; Botulinum Toxins; Cell- and Tissue-Based Therapy; Cerebral Palsy; Combined Modality Therap | 2013 |
Major surgical procedures in children with cerebral palsy.
Topics: Anesthetics; Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Kyphosis; Muscle Relaxants | 2014 |
Scoliosis, spinal fusion, and intrathecal baclofen pump implantation.
Topics: Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Muscle Spa | 2015 |
Intrathecal baclofen bolus dosing and catheter tip placement in pediatric tone management.
Topics: Adolescent; Baclofen; Catheterization; Cerebral Palsy; Drug Administration Schedule; Humans; Infusio | 2015 |
Pharmacological interventions for pain in children and adolescents with life-limiting conditions.
Topics: Adolescent; Alendronate; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool | 2015 |
[Intrathecal Baclofen Therapy for Cerebral Palsy].
Topics: Animals; Baclofen; Brain; Cerebral Palsy; Humans; Injections, Spinal; Muscle Spasticity; Treatment O | 2015 |
Neurosurgical Management of Childhood Spasticity: Functional Posterior Rhizotomy and Intrathecal Baclofen Infusion Therapy.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Rhizotomy | 2015 |
Effectiveness of Oral Baclofen in the Treatment of Spasticity in Children and Adolescents With Cerebral Palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Male; Muscle Relaxant | 2016 |
Intrathecal baclofen for treating spasticity in children with cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Injections, Spinal; Muscle Re | 2015 |
Clinical practices in intrathecal baclofen pump implantation in children with cerebral palsy in France.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; France; Humans; Infusion Pumps, Implantable; Infu | 2016 |
Intrathecal Baclofen Therapy for the Treatment of Spasticity in Lithuania.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Epidural Abscess; Humans; Infusion Pumps, Implan | 2017 |
Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain.
Topics: Adult; Baclofen; Catheterization; Cerebral Palsy; Child; Child, Preschool; Dose-Response Relationshi | 2008 |
Intrathecal baclofen use in adults with cerebral palsy.
Topics: Adult; Baclofen; Catheterization; Cerebral Palsy; Humans; Injections, Spinal; Muscle Relaxants, Cent | 2009 |
Intrathecal baclofen and pregnancy: implications for clinical care.
Topics: Adolescent; Baclofen; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Injections, Spina | 2009 |
Treating complex movement disorders in children with cerebral palsy.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Deep Brain Stimulation; Humans; Infusion Pumps, Implanta | 2009 |
Pharmacotherapy of spasticity in children with cerebral palsy.
Topics: Baclofen; Benzodiazepines; Cerebral Palsy; Child; Clonidine; Dantrolene; Humans; Muscle Spasticity; | 2011 |
The treatment of cerebral palsy: What we know, what we don't know.
Topics: Activities of Daily Living; Baclofen; Botulinum Toxins, Type A; Brain; Cerebral Palsy; Complementary | 2004 |
[Botulinum toxin type A in the treatment plan for cerebral palsy].
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; C | 2001 |
Pharmacologic interventions for reducing spasticity in cerebral palsy.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen | 2005 |
Therapeutic interventions for tone abnormalities in cerebral palsy.
Topics: Administration, Oral; Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Cerebral Palsy; Humans; Mu | 2006 |
Management of childhood spasticity: a neurosurgical perspective.
Topics: Baclofen; Cerebral Palsy; Humans; Infant; Injections, Spinal; Muscle Relaxants, Central; Muscle Spas | 2006 |
Selection of treatment modalities in children with spastic cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Clinical Protocols; Humans; Muscle Relaxants, Cen | 2006 |
A review of the complications of intrathecal baclofen in patients with cerebral palsy.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Infusions, | 2007 |
[Physical and other methods therapy of the spasticity in children].
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Drug Administration Schedule; Humans; Inf | 2007 |
Intrathecal baclofen in cerebral palsy movement disorders.
Topics: Baclofen; Cerebral Palsy; Health Care Costs; Humans; Infusion Pumps, Implantable; Injections, Spinal | 1996 |
[Cerebral palsy therapy].
Topics: Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Combined Modality Therap | 1997 |
The management of cerebral palsy: how can neurosurgery help?
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; GABA Agonists; Huma | 1997 |
Evidence of the effects of intrathecal baclofen for spastic and dystonic cerebral palsy. AACPDM Treatment Outcomes Committee Review Panel.
Topics: Baclofen; Cerebral Palsy; Child; Clinical Trials as Topic; Humans; Injections, Spinal; Leg; Muscle R | 2000 |
Baclofen infusion for spastic cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Rel | 2000 |
Spasticity management: an overview.
Topics: Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Cerebral Palsy; Child, Preschool; Exercise; GABA | 2001 |
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Pal | 2001 |
Neurosurgery for spasticity.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Combined Modality Therapy; Gai | 2000 |
Baclofen overdose in two siblings.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Drug Overdose; Family Health; Humans; Infant; Mus | 2001 |
Therapeutic choices in the locomotor management of the child with cerebral palsy--more luck than judgement?
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Gait Disorders, Neurologic; Humans; Injec | 2001 |
Intrathecal baclofen therapy for spastic hypertonia.
Topics: Baclofen; Cerebral Palsy; Drug Overdose; GABA Agonists; Humans; Injections, Spinal; Multiple Scleros | 2001 |
[Treatment of spasticity].
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Clonidine; Humans; Injections, Spinal; Muscle Re | 1999 |
[Recent progress in pediatric neurological rehabilitation].
Topics: Adolescent; Adult; Age Factors; Animals; Baclofen; Botulinum Toxins; Central Nervous System Diseases | 2002 |
Neurosurgical treatment of spasticity: selective posterior rhizotomy and intrathecal baclofen.
Topics: Adolescent; Adult; Animals; Baclofen; Cerebral Palsy; Child; Female; Humans; Injections, Spinal; Mal | 1992 |
[Functional neurosurgery of cerebral palsy].
Topics: Adolescent; Adult; Animals; Baclofen; Benzodiazepines; Brain; Brain Diseases; Cerebellar Cortex; Cer | 1985 |
35 trials available for baclofen and Cerebral Palsy
| Article | Year |
|---|---|
Attainment of personal goals in the first year of intrathecal baclofen treatment in dyskinetic cerebral palsy: a prospective cohort study.
Topics: Baclofen; Cerebral Palsy; Child; Cohort Studies; Dystonia; Goals; Humans; Injections, Spinal; Muscle | 2023 |
Use of the Dyskinesia Impairment Scale in non-ambulatory dyskinetic cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Disability Evaluation; Dyskinesias; Female; Humans; Inj | 2020 |
Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy.
Topics: Administration, Oral; Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dose-Response R | 2018 |
The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Female; H | 2019 |
Intrathecal baclofen treatment in dystonic cerebral palsy: a randomized clinical trial: the IDYS trial.
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Brain; Cerebral Palsy; Child; Child, Presch | 2013 |
Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy.
Topics: Absorption; Administration, Oral; Adolescent; Baclofen; Body Weight; Cerebral Palsy; Child; Child, P | 2014 |
Comparative study of therapeutic response to baclofen vs tolperisone in spasticity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baclofen; Cerebral Palsy; Child; Child, Preschool; Femal | 2017 |
Long-term therapy with intrathecal baclofen improves quality of life in children with severe spastic cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusion Pumps, Impla | 2017 |
Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Disability Evaluation; Follow-Up Studies; Humans; Infus | 2009 |
The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy.
Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Disease Progres | 2008 |
Botulinum toxin type A with oral baclofen versus oral tizanidine: a nonrandomized pilot comparison in patients with cerebral palsy and spastic equinus foot deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Chi-Square Dis | 2008 |
Intrathecal baclofen infusion for ambulant children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gait; | 2009 |
Controlled study of the effects of continuous intrathecal baclofen infusion in non-ambulant children with cerebral palsy.
Topics: Adolescent; Analysis of Variance; Baclofen; Case-Control Studies; Cerebral Palsy; Child; Child, Pres | 2011 |
The effect of intrathecal baclofen on muscle co-contraction in children with spasticity of cerebral origin.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Electromyography; Female; Follow-Up Studies; Humans; In | 2002 |
Intrathecal baclofen therapy in children with cerebral palsy: efficacy and complications.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Equipment Failure; Female; Humans; In | 2002 |
Functional assessment following intrathecal baclofen therapy in children with spastic cerebral palsy.
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Co | 2003 |
Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children.
Topics: Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dystonia; Evoked Potentials, Motor; Female | 2004 |
'Effects of oral baclofen on children with cerebral palsy'.
Topics: Administration, Oral; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Male; Muscl | 2004 |
Performance and complications associated with the synchromed 10-ml infusion pump for intrathecal baclofen administration in children.
Topics: Adolescent; Age Factors; Baclofen; Body Mass Index; Cerebral Palsy; Child; Child, Preschool; Female; | 2004 |
Oral baclofen in children with cerebral palsy: a double-blind cross-over pilot study.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Humans; Muscle Spasticity; N | 2006 |
Cost-effectiveness of intrathecal baclofen therapy for the treatment of severe spasticity associated with cerebral palsy.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Cost-Benefit Analysis; Female; | 2007 |
Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Double-Blind Method; Female; Humans; Injections, Spinal | 2007 |
Complex dosing schedules for continuous intrathecal baclofen infusion.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Dose-Response Relationship, Drug; Drug Administr | 2007 |
Intrathecal baclofen for spasticity of cerebral palsy: project coordination and nursing care.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Follow-Up Studies; Humans; Infusion Pumps, Impla | 1995 |
Multidimensional assessment of motor function in a child with cerebral palsy following intrathecal administration of baclofen.
Topics: Activities of Daily Living; Baclofen; Cerebral Palsy; Child; Double-Blind Method; Electromyography; | 1997 |
Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin.
Topics: Adolescent; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Humans; Infusion Pump | 1997 |
Plasma baclofen levels in children receiving continuous intrathecal baclofen infusion.
Topics: Administration, Oral; Adolescent; Baclofen; Cerebral Palsy; Child; Female; Humans; Injections, Intra | 1999 |
Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Dystonia Musculorum Deformans; Follow-U | 1999 |
Intrathecal baclofen for management of spastic cerebral palsy: multicenter trial.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dose-Response Relationship, Dr | 2000 |
Intrathecal baclofen for intractable cerebral spasticity: a prospective placebo-controlled, double-blind study.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Double-Blind Method; Female; Humans; Infusion Pu | 2000 |
Intrathecal baclofen is analgesic in patients with chronic pain.
Topics: Aged; Amputation, Surgical; Baclofen; Cerebral Palsy; Chronic Disease; Female; GABA Agonists; Hemato | 2000 |
Intrathecal baclofen for generalized dystonia.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dystonia; Female; Follow-Up St | 2001 |
A controlled trial of baclofen in children with cerebral palsy.
Topics: Adolescent; Aminobutyrates; Baclofen; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as To | 1977 |
Long-term intrathecal baclofen treatment in supraspinal spasticity.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Humans; Infusion Pumps; Injections, Spinal; Male; M | 1992 |
Intrathecal baclofen for spasticity in cerebral palsy.
Topics: Adolescent; Adult; Arm; Baclofen; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Fema | 1991 |
202 other studies available for baclofen and Cerebral Palsy
| Article | Year |
|---|---|
Epidural Analgesia Versus Lumbar Plexus Blockade After Hip Reconstruction Surgery in Children With Cerebral Palsy and Intrathecal Baclofen Pumps: A Comparison of Safety and Efficacy.
Topics: Analgesia, Epidural; Baclofen; Cerebral Palsy; Child; Female; Humans; Lumbosacral Plexus; Male; Pain | 2022 |
A Severe Baclofen Intoxication Mimicking Post-Hypoxic Encephalopathy: Wait and See!
Topics: Baclofen; Brain Death; Cerebral Palsy; Coma; Humans; Hypoxia, Brain; Injections, Spinal; Male | 2022 |
Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps.
Topics: Anesthesia; Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Muscle Relaxants, | 2022 |
Efficacy of Selective Dorsal Rhizotomy and Intrathecal Baclofen Pump in the Management of Spasticity.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Muscle Spasticity; Quality of Life; Rhizotomy; Treatment Ou | 2022 |
Cerebral Palsy: Current Concepts and Practices in Musculoskeletal Care.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Humans; Infant, Newborn; Quality of Life; Rhizoto | 2022 |
Femoral Head Deformity Associated With Hip Displacement in Nonambulatory Cerebral Palsy: Results at Skeletal Maturity.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Coxa Magna; Hip Dislocation; Humans; Osteoarthritis; Re | 2023 |
Letter to the Editor. Intrathecal baclofen pump insertion versus selective dorsal rhizotomy.
Topics: Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Relaxants, | 2022 |
Does intrathecal baclofen therapy decrease the progression of hip displacement in young patients with cerebral palsy?
Topics: Baclofen; Cerebral Palsy; Child; Hip Dislocation; Humans; Muscle Spasticity; Retrospective Studies | 2023 |
A multicenter initiative to reduce intrathecal baclofen pump surgical site infection: a Cerebral Palsy Research Network quality improvement project.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Rel | 2023 |
A critical evaluation of oral baclofen in pediatric patients with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Mus | 2023 |
CNS adverse effects of intrathecal baclofen treatment for spasticity in children with cerebral palsy and epilepsy: a case report.
Topics: Baclofen; Cerebral Palsy; Child; Epilepsy; Humans; Injections, Spinal; Muscle Relaxants, Central; Mu | 2023 |
Is baclofen the least worst option for spasticity management in children?
Topics: Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spast | 2023 |
Benefit of enteral baclofen in the management of spasticity in cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Muscle Spa | 2023 |
Use of intraoperative topical antibiotics to reduce intrathecal baclofen pump surgical site infections: a single institution's experience over 24 years.
Topics: Anti-Bacterial Agents; Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Injections, Sp | 2023 |
The use of botulinum toxin and intrathecal baclofen in hip dysplasia in cerebral palsy.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Hip Dislocation; Humans; Injections, Spinal; Muscle Rela | 2023 |
Intrathecal baclofen therapy does not prevent hip displacement in children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Hip Dislocation; Humans; Infusion Pumps, Implantable; Injections, S | 2023 |
Identification of risk factors for reconstructive hip surgery after intrathecal baclofen therapy in children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Male; Muscle Spasticity; Radiography; Ris | 2023 |
[Methods and results of neurosurgical treatment of cerebral palsy].
Topics: Baclofen; Cerebral Palsy; Dystonia; Humans; Muscle Spasticity; Neurosurgical Procedures; Paralysis; | 2023 |
Intracerebroventricular baclofen therapy improves function and quality of life in a child with severe cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Movement Disorders; Muscle Rel | 2023 |
Intrathecal baclofen therapy for treatment of spasticity in infants and small children under 6 years of age.
Topics: Baclofen; Catheters, Indwelling; Cerebral Palsy; Child; Child, Preschool; Humans; Infant; Infusion P | 2020 |
Laparoscopic fundoplication for a child with abdominal intrathecal Baclofen pump.
Topics: Baclofen; Cerebral Palsy; Child; Fundoplication; Gastroesophageal Reflux; Humans; Laparoscopy | 2020 |
Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy.
Topics: Administration, Oral; Adolescent; Baclofen; Body Weight; Cerebral Palsy; Child; Child, Preschool; Cr | 2020 |
The effectiveness of epidural blood patch in patients with cerebral palsy treated with intrathecal baclofen implantation.
Topics: Baclofen; Blood Patch, Epidural; Cerebral Palsy; Cerebrospinal Fluid Leak; Child; Cohort Studies; Fe | 2020 |
Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy?
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Disease Progression; Female; Humans; Infusion Pu | 2020 |
Access to Intrathecal Baclofen Treatment for Children with Cerebral Palsy in European Countries: An SCPE Survey Reveals Important Differences.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Europe; Female; Gross Domestic Produc | 2020 |
The Impact of Intrathecal Baclofen Therapy on Health-related Quality of Life for Children with Marked Hypertonia.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Disabled Children; Fe | 2020 |
Evaluation of Risk Factors for Cerebrospinal Leakage in Pediatric Patients With Cerebral Palsy Treated With Intrathecal Baclofen.
Topics: Adolescent; Baclofen; Cerebral Palsy; Cerebrospinal Fluid Leak; Child; Child, Preschool; Female; Hum | 2020 |
Baclofen pump with pre-brainstem catheter tip placement: technical note and case series.
Topics: Baclofen; Brain Stem; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central | 2021 |
Long term outcome of Selective Dorsal Rhizotomy for the management of childhood spasticity-functional improvement and complications.
Topics: Activities of Daily Living; Baclofen; Cerebral Palsy; Humans; Muscle Spasticity; Rhizotomy; Treatmen | 2020 |
Increasingly Familiar Breathing Pattern in an Unfamiliar Population. Sleep-related Breathing Disorders in High-Risk Patients.
Topics: Apnea; Baclofen; Cerebral Palsy; Child; Female; Humans; Polysomnography; Sleep; Sleep Apnea, Central | 2020 |
A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report.
Topics: Arginase; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; China; Diet, Protein-Restricted; Humans | 2020 |
Epidural catheter placement in children with baclofen pumps.
Topics: Baclofen; Catheters; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; | 2021 |
Complications of intrathecal baclofen pump treatment in children with spastic cerebral palsy. A comparative analysis of patients weighing over or under 20 kg at the time of implantation.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Muscle | 2022 |
National surveillance of oral medication prescription for children with dystonic cerebral palsy.
Topics: Australia; Baclofen; Cerebral Palsy; Child; Drug Prescriptions; Humans; Prospective Studies | 2021 |
Unusual mechanical failures of intrathecal baclofen pump systems: symptoms, signs, and trouble shooting.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Rel | 2021 |
Intrathecal baclofen pumps in the management of hypertonia in childhood: a UK and Ireland wide survey.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Humans; Inje | 2021 |
Pediatric Intrathecal Baclofen Pumps: A Descriptive Analysis of Hospital Course and Associated Costs.
Topics: Baclofen; Cerebral Palsy; Child; Comorbidity; Hospitals; Humans; Length of Stay | 2021 |
Sleep-related breathing disorders associated with intrathecal baclofen therapy to treat patients with cerebral palsy: A cohort study and discussion.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Injections, Spinal; Male; Muscle Relaxant | 2021 |
Treatment of spasticity in children and adolescents with cerebral palsy in Northern Europe: a CP-North registry study.
Topics: Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Cohort Stud | 2021 |
Lumbar translaminar fenestration for insertion of intrathecal baclofen catheter: a novel technique.
Topics: Adolescent; Baclofen; Catheters, Indwelling; Cerebral Palsy; Humans; Lumbar Vertebrae; Male; Muscle | 2017 |
The effect of continuous intrathecal baclofen therapy on ambulatory children with cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; In | 2018 |
Nurse Practitioner Lead Pediatric Baclofen Pump Program: Impact on Safety and Quality of Care.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Mus | 2017 |
Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Inject | 2017 |
Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis?
Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Chi-Square Distribution; Child; Disease | 2017 |
Oral medication prescription practices of tertiary-based specialists for dystonia in children with cerebral palsy.
Topics: Administration, Oral; Adolescent; Australia; Baclofen; Central Nervous System Agents; Cerebral Palsy | 2018 |
Ask the Authors.
Topics: Baclofen; Cerebral Palsy; Child; Humans; Pharmacogenetics | 2018 |
Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity.
Topics: Baclofen; Cerebral Palsy; Child; Dystonia; Female; Humans; Injections, Spinal; Male; Motor Activity; | 2018 |
Intrathecal baclofen therapy in children: an analysis of individualized goals.
Topics: Adolescent; Australia; Baclofen; Cerebral Palsy; Child; Cohort Studies; Female; Goals; Humans; Injec | 2018 |
Hidden Medical Devices in the School Setting: What the School Nurse Needs to Know About the Safe Use of Baclofen Pumps.
Topics: Baclofen; Cerebral Palsy; Child; Clinical Competence; Humans; Infusion Pumps, Implantable; Male; Mus | 2018 |
Placement of baclofen pump catheter through a C1-2 puncture: technical note.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Epilepsy; Female; Humans; Infusion Pu | 2018 |
An Unreported Cause of Intrathecal Baclofen Withdrawal Symptoms in a Woman With Spastic Cerebral Palsy Who Received Intrathecal Gablofen.
Topics: Adult; Baclofen; Cerebral Palsy; Female; Humans; Injections, Spinal; Muscle Relaxants, Central; Musc | 2018 |
Title: Quantifying the change of spasticity after intrathecal baclofen administration: A descriptive retrospective analysis.
Topics: Adult; Aged; Baclofen; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Injections, Spin | 2018 |
Intrathecal Baclofen Pump Versus Globus Pallidus Interna Deep Brain Stimulation in Adult Patients with Severe Cerebral Palsy.
Topics: Adult; Baclofen; Cerebral Palsy; Deep Brain Stimulation; Female; Globus Pallidus; Humans; Infusion P | 2019 |
Muscle spasm-induced exothermia in dystonic cerebral palsy: uncommon and frequently misdiagnosed condition.
Topics: Baclofen; Cerebral Palsy; Diagnosis, Differential; Dystonic Disorders; Electromyography; Fluid Thera | 2019 |
Pharmacological management of abnormal tone and movement in cerebral palsy.
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Prescho | 2019 |
Use of botulinum toxin A in children with cerebral palsy.
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Cross-Sectional Studies; Female; Humans; | 2019 |
Comparing the effects of two spasticity management strategies on the long-term outcomes of individuals with bilateral spastic cerebral palsy: a multicentre cohort study protocol.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Management; Female; Follow-Up Studies; Fo | 2019 |
Investigating the Feasibility of a Modified Quantitative Sensory Testing Approach to Profile Sensory Function and Predict Pain Outcomes Following Intrathecal Baclofen Implant Surgery in Cerebral Palsy.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Feasibility Studies; Female; Humans; Infusion Pu | 2020 |
Improvements in children with cerebral palsy following intrathecal baclofen: use of the Rehabilitation Institute of Chicago Care and Comfort Caregiver Questionnaire (RIC CareQ).
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Caregivers; Cerebral Palsy; Child; Child, P | 2014 |
Dose-dependent relapse of hiatus hernia after administration of intrathecal baclofen treatment--a rare complication.
Topics: Adolescent; Baclofen; Cerebral Palsy; Dose-Response Relationship, Drug; Hernia, Hiatal; Humans; Infu | 2013 |
Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy.
Topics: Adolescent; Baclofen; Caregivers; Cerebral Palsy; Child; Female; Humans; Injections, Spinal; Longitu | 2013 |
The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusion Pumps, Impla | 2014 |
Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience.
Topics: Adolescent; Baclofen; Catheters, Indwelling; Cerebral Palsy; Child; Child, Preschool; Dystonia; Dyst | 2014 |
Occurrence of adverse events in long-term intrathecal baclofen infusion: a 1-year follow-up study of 158 adults.
Topics: Adolescent; Adult; Age Distribution; Aged; Baclofen; Cerebral Palsy; Dose-Response Relationship, Dru | 2014 |
Intrathecal baclofen toxicity: an unusual cause of paediatric postoperative coma and respiratory depression.
Topics: Adolescent; Baclofen; Cerebral Palsy; Coma; Humans; Injections, Spinal; Male; Muscle Relaxants, Cent | 2014 |
Orthopedic surgery in children with intrathecal baclofen pumps.
Topics: Adolescent; Age Factors; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; | 2013 |
Patient experiences with intrathecal baclofen as a treatment for spasticity - a pilot study.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Cerebral Palsy; Female; Humans; Injections, Spina | 2015 |
Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity.
Topics: Acute Disease; Adult; Baclofen; Cerebral Palsy; Dose-Response Relationship, Drug; Female; GABA-B Rec | 2014 |
Indwelling intrathecal catheter with subcutaneous abdominal reservoir: a viable baclofen delivery system in severely cachectic patients.
Topics: Baclofen; Cachexia; Catheters, Indwelling; Cerebral Palsy; Child; Dystonia; Humans; Infusion Pumps, | 2014 |
Dexmedetomidine for acute baclofen withdrawal.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Baclofen; Cerebral Palsy; Dexmedetomidine; GABA-B | 2015 |
Spasticity.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Humans; Multiple Sclerosis; Muscle Relaxants, Central; M | 2015 |
Pediatric rehabilitation.
Topics: Amputation, Surgical; Baclofen; Caregivers; Cerebral Palsy; Child; Disabled Children; Humans; Muscle | 2015 |
Positive experience with intrathecal baclofen treatment in children with severe cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Denmark; Dystonia; Female; Humans; In | 2015 |
Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy.
Topics: Adolescent; Baclofen; Blood Loss, Surgical; Catheters, Indwelling; Cerebral Palsy; Child; Cicatrix; | 2015 |
Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump.
Topics: Baclofen; Cerebral Palsy; Child; Device Removal; Drug Overdose; Equipment Failure; GABA-B Receptor A | 2015 |
Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, | 2016 |
Baclofen pump catheter leakage after migration of the abdominal catheter in a pediatric patient with spasticity.
Topics: Abdomen; Adolescent; Baclofen; Catheters, Indwelling; Cerebral Palsy; Foreign-Body Migration; Humans | 2015 |
Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy.
Topics: Adolescent; Analgesia, Epidural; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; | 2015 |
Combined selective dorsal rhizotomy and scoliosis correction procedure in patients with cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Device Removal; Female; Humans; Infusion Pumps, Implantable; M | 2016 |
Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly.
Topics: Baclofen; Bradycardia; Cerebral Palsy; Child; Female; Humans; Hydranencephaly; Injections, Spinal; M | 2015 |
[Scintigraphic imaging in the diagnosis of failed intrathecal baclofen therapy: a case report of a 7-year-old boy with ventriculoperitoneal shunt].
Topics: Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Magnetic Resonance Imaging; Male; Multi | 2015 |
Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review.
Topics: Adult; Aged; Baclofen; Brain Injuries; Cerebral Palsy; Dose-Response Relationship, Drug; Female; Hum | 2016 |
[Preliminary results of chronic intrathecal therapy in treatment of spastic syndromes of various etiologies].
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Humans; Infusions, Spinal; Muscle Relaxants, | 2015 |
Selective dorsal rhizotomy as an alternative to intrathecal baclofen pump replacement in GMFCS grades 4 and 5 children.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Female; Humans; Infusion Pumps, Implantable; Infusions, | 2016 |
The effect of intrathecal baclofen treatment on activities of daily life in children and young adults with cerebral palsy and progressive neurological disorders.
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Cross-Sectional Stud | 2016 |
Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy.
Topics: Baclofen; Case-Control Studies; Cerebral Palsy; Child; Cohort Studies; Disease Progression; Female; | 2017 |
Status dystonicus in children: Early recognition and treatment prevent serious complications.
Topics: Adolescent; Anti-Dyskinesia Agents; Athetosis; Baclofen; Cerebral Palsy; Child; Disease Progression; | 2016 |
[A Pediatric Case of Intractable Cerebrospinal Fluid Leakage after Implantation of an Intrathecal Baclofen Pump].
Topics: Abdomen; Baclofen; Cerebral Palsy; Cerebrospinal Fluid Leak; Child; Disease Progression; Female; Hum | 2017 |
Image-guided intrathecal baclofen pump catheter implantation: a technical note and case series.
Topics: Adolescent; Adult; Anesthesia, General; Baclofen; Catheters, Indwelling; Cerebral Palsy; Cone-Beam C | 2017 |
Safety and one-year efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Female; Follow-Up Studies; Humans; Infusion Pumps, Impl | 2009 |
Effect of intrathecal baclofen concentration on spasticity control: case series.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Female; GABA Agonists; Humans; Infusion Pumps; Inje | 2008 |
Epidural analgesia in labor for a woman with an intrathecal baclofen pump.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Baclofen; Catheterization; Cerebral Palsy; Fema | 2009 |
Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy.
Topics: Abdominal Pain; Adolescent; Autonomic Dysreflexia; Baclofen; Cerebral Palsy; Diagnosis, Differential | 2008 |
[Intrathecal baclofen therapy. Overdose during replacement of a medication pump].
Topics: Anesthesia, General; Baclofen; Cerebral Palsy; Child; Drug Overdose; Humans; Infusion Pumps, Implant | 2009 |
[Neuromodulation of spasticity in children by intrathecal baclofen].
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disability Evaluation; Dose-Response | 2009 |
Survival of individuals with cerebral palsy receiving continuous intrathecal baclofen treatment: a matched-cohort study.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Cohort Studies; Epilepsy; Fema | 2010 |
Intrathecal baclofen.
Topics: Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Hypertonia | 2010 |
Concomitant correction of spinal deformity and spasticity management with posterior instrumentation and baclofen pump implantation.
Topics: Adolescent; Baclofen; Bone Nails; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Injec | 2009 |
Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge?
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disability Evaluation; Disabled Child | 2010 |
Intracranial migration of a fractured intrathecal catheter from a baclofen pump system: case report and analysis of possible causes.
Topics: Adolescent; Baclofen; Cerebral Palsy; Equipment Failure; Foreign-Body Migration; Humans; Infusion Pu | 2010 |
Do baclofen pumps influence the development of scoliosis in children?
Topics: Adolescent; Aging; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Dystonia; | 2010 |
Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2010 |
Long-term oral baclofen treatment in a child with cerebral palsy: electroencephalographic changes and clinical adverse effects.
Topics: Baclofen; Brain; Brain Waves; Cerebral Palsy; Child; Electroencephalography; Epilepsy; Female; GABA- | 2010 |
Changes in gait following continuous intrathecal baclofen infusion in ambulant children and young adults with cerebral palsy.
Topics: Adolescent; Baclofen; Biomechanical Phenomena; Cerebral Palsy; Child; Female; Gait Disorders, Neurol | 2009 |
Health care services for adults with cerebral palsy.
Topics: Adolescent; Adult; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Disabled Persons; Female; Gas | 2010 |
Malfunction of SynchroMed II baclofen pump delivers a near-lethal baclofen overdose.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Equipment Failure; Female; Humans; Infusion Pumps, I | 2010 |
Intrathecal baclofen in cerebral palsy. A retrospective study of 25 wheelchair-assisted adults.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Female; GABA-B Receptor Agonists; Humans; Infusion Pump | 2010 |
Intrathecal baclofen therapy: complication avoidance and management.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Equipment Fail | 2011 |
Intrathecal baclofen and motor function in cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Movement Disorders | 2011 |
Intrathecal baclofen and motor function in cerebral palsy.
Topics: Adolescent; Adult; Age Factors; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disability Evalua | 2011 |
The effects of continuous intrathecal baclofen infusion in non-ambulant children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Muscle Relaxants, Central | 2011 |
Intrathecal baclofen therapy: benefits and complications.
Topics: Adolescent; Australia; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusion P | 2011 |
Paraspinal subfascial placement of lumbar intrathecal baclofen catheters: short-term outcomes of a novel technique.
Topics: Adolescent; Adult; Baclofen; Catheters, Indwelling; Cerebral Palsy; Child; Child, Preschool; Dystoni | 2012 |
Intrathecal baclofen pump: a foreign-body reaction case report and its solution.
Topics: Adult; Baclofen; Cerebral Palsy; Female; Foreign-Body Reaction; Humans; Infusion Pumps, Implantable; | 2012 |
Effects of intrathecal baclofen therapy on motor and cognitive functions in a rat model of cerebral palsy.
Topics: Animals; Animals, Newborn; Baclofen; Cerebral Palsy; Cognition Disorders; Electric Stimulation; Evok | 2012 |
Cervical catheter placement for intrathecal baclofen test dose: is it safe?
Topics: Adolescent; Baclofen; Brain Diseases, Metabolic, Inborn; Catheterization; Catheters, Indwelling; Cer | 2012 |
Spasticity in children and young people with non-progressive brain disorders: summary of NICE guidance.
Topics: Adolescent; Baclofen; Botulinum Toxins, Type A; Brain Diseases; Cerebral Palsy; Child; Humans; Injec | 2012 |
Intraventricular baclofen as an alternative to intrathecal baclofen for intractable spasticity or dystonia: outcomes and technical considerations.
Topics: Adolescent; Adult; Aged; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Dystonic | 2012 |
Evaluation of salvage techniques for infected baclofen pumps in pediatric patients with cerebral palsy.
Topics: Adolescent; Anti-Bacterial Agents; Baclofen; Cerebral Palsy; Child; Child, Preschool; Device Removal | 2012 |
A comparison of hip dislocation rates and hip containment procedures after selective dorsal rhizotomy versus intrathecal baclofen pump insertion in nonambulatory cerebral palsy patients.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; Follow-U | 2012 |
[Spasticity in children cerebral palsy: diagnosis and treatment strategies].
Topics: Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Humans; | 2012 |
Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report.
Topics: Acute Disease; Adolescent; Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Leg; Male; Muscle H | 2002 |
Long-term safety and efficacy of continuous intrathecal baclofen.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Equip | 2002 |
The role of surgical placement and pump orientation in intrathecal pump system failure: a technical report.
Topics: Analgesia, Epidural; Baclofen; Catheters, Indwelling; Cerebral Palsy; Child; Device Removal; Equipme | 2003 |
[Value of intrathecal baclofen in the treatment of spastic cerebral palsy].
Topics: Baclofen; Cerebral Palsy; Child; Equipment Design; GABA Agonists; Humans; Infusion Pumps; Infusions, | 2003 |
Oral motor, communication, and nutritional status of children during intrathecal baclofen therapy: a descriptive pilot study.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Communication; Cross-Sectional Studies; Disabled | 2003 |
Intrathecal baclofen therapy in children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Clinical Trials as Topic; Humans; Infusion Pumps, Implantable; Inje | 2003 |
Cyproheptadine for intrathecal baclofen withdrawal.
Topics: Acute Disease; Adult; Baclofen; Cerebral Palsy; Cyproheptadine; Diagnosis, Differential; Female; Fev | 2003 |
Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait.
Topics: Adult; Ankle; Baclofen; Biomechanical Phenomena; Body Weight; Brain Injuries; Cerebral Palsy; Electr | 2003 |
Oral baclofen in cerebral palsy: possible seizure potentiation?
Topics: Administration, Oral; Baclofen; Cerebral Palsy; Child; Humans; Retrospective Studies; Seizures | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
Spasticity in adults living in a developmental center.
Topics: Activities of Daily Living; Adult; Aged; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Comorbi | 2003 |
[Intrathecal baclofen for treatment of spasticity in patient with cerebral palsy--a preliminary report].
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Electromyography; Female; Humans; Infusion Pumps, Impla | 2003 |
Mechanical measurements of the effects of intrathecal baclofen dosage adjustments in cerebral palsy: a pilot study.
Topics: Adolescent; Adult; Baclofen; Biomechanical Phenomena; Cerebral Palsy; Dose-Response Relationship, Dr | 2004 |
Baclofen toxicity in an 8-year-old with an intrathecal baclofen pump.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Equipment Design; Equipment Failure; Equipment Failu | 2004 |
Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Hip | 2004 |
Effect of baclofen on emesis and 24-hour esophageal pH in neurologically impaired children with gastroesophageal reflux disease.
Topics: Administration, Oral; Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; De Lange Syndro | 2004 |
Care provider assessment of intrathecal baclofen in children.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Female; Humans | 2004 |
Treatment of childhood spasticity of cerebral origin with intrathecal baclofen: a series of 52 cases.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; GABA Agonists; Humans; Infusi | 2004 |
Intrathecal baclofen therapy over 10 years.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Drug Implants; | 2004 |
An unusual cause of overdose after baclofen pump implantation: case report.
Topics: Adolescent; Baclofen; Cerebral Palsy; Consciousness Disorders; Contrast Media; Drug Overdose; Dyston | 2005 |
[Intrathecal baclofen and Botulinum toxin in infantile cerebral palsy].
Topics: Baclofen; Cerebral Palsy | 2005 |
[A child case treated with intrathecal baclofen: effectiveness for the spasticity in lower extremities].
Topics: Baclofen; Cerebral Palsy; Child; Female; GABA Agonists; Humans; Injections, Spinal; Muscle Spasticit | 2005 |
Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Drug Delivery Systems; Headache; Humans; Injections, Sp | 2005 |
A novel approach to prevent repeated catheter migration in a patient with a baclofen pump: a case report.
Topics: Adult; Baclofen; Cerebral Palsy; Female; Foreign-Body Migration; Humans; Infusion Pumps, Implantable | 2005 |
Prevention of severe contractures might replace multilevel surgery in cerebral palsy: results of a population-based health care programme and new techniques to reduce spasticity.
Topics: Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Contrac | 2005 |
Placement of baclofen pumps through the foramen magnum and upper cervical spine.
Topics: Adolescent; Adult; Baclofen; Catheters, Indwelling; Cerebral Palsy; Cervical Vertebrae; Child; Femal | 2006 |
Epilepsy and intrathecal baclofen therapy in children with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child, Preschool; Epilepsy, Generalized; Humans; Infant; Infusion Pumps, I | 2005 |
Posterior cervical approach for intrathecal baclofen pump insertion in children with previous spinal fusions. Technical note.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Cervical Vertebrae; Female; Humans; Infusion Pumps; Inj | 2005 |
Intrathecal baclofen overdose followed by withdrawal: clinical and EEG features.
Topics: Baclofen; Brain Diseases; Cerebral Palsy; Child; Drug Overdose; Electroencephalography; Humans; Inje | 2005 |
Best-practice surgical techniques for intrathecal baclofen therapy.
Topics: Baclofen; Catheters, Indwelling; Cerebral Palsy; Child; Dystonia; Equipment Design; GABA Agonists; H | 2006 |
Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy.
Topics: Adult; Baclofen; Cerebral Palsy; Dysarthria; GABA Agonists; Humans; Infusion Pumps, Implantable; Inj | 2006 |
Intrathecal baclofen overdose and withdrawal.
Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Humans; Infusion Pumps, Implantable; Injections, Spi | 2006 |
[Spasticity management and progress in ambulatory cerebral palsy].
Topics: Ambulatory Care; Baclofen; Biomechanical Phenomena; Botulinum Toxins, Type A; Cerebral Palsy; Child; | 2006 |
Gram-negative meningitis and infections in individuals treated with intrathecal baclofen for spasticity: a retrospective study.
Topics: Adolescent; Adult; Baclofen; Bacterial Infections; Cerebral Palsy; Child; Enterobacter aerogenes; En | 2006 |
The use of an indium111 DTPA flow study in the evaluation of a lumbar swelling in a girl with a baclofen pump.
Topics: Adolescent; Baclofen; Cerebral Palsy; Cysts; Equipment Failure; Female; Humans; Indium Radioisotopes | 2006 |
Baclofen-induced sexual dysfunction.
Topics: Adult; Baclofen; Cerebral Palsy; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Sexua | 2006 |
Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy.
Topics: Adolescent; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Female; Hospitals, Pe | 2006 |
Oral baclofen and clonidine for treatment of spasticity in children.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Age Factors; Baclofen; Brain Inj | 2006 |
Is it worth the risk?
Topics: Anesthesia, Epidural; Baclofen; Catheterization; Cerebral Palsy; Child; Humans; Injections, Spinal; | 2007 |
Intravenous diazepam infusion in the management of planned intrathecal baclofen withdrawal.
Topics: Adolescent; Adult; Anticonvulsants; Baclofen; Cerebral Palsy; Child; Diazepam; Drug Administration S | 2007 |
The use of intrathecal baclofen pump implants in children and adolescents: safety and complications in 200 consecutive cases.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusion Pumps, Impla | 2007 |
The role of intrathecal baclofen in the management of primary and secondary dystonia in children.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dystonia; Female; Humans; Infu | 2007 |
Surgical management of spasticity of cerebral origin in children.
Topics: Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusion Pumps, Implantable; Inje | 2007 |
Intrathecal Baclofen: a discussion on impact that medical advances can have on the individual and the implications this has for a society that is built on an ethic of social medicine.
Topics: Adult; Baclofen; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Cent | 2008 |
The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; Humans; | 2007 |
[The parents expectations after baclofen pump implantation in child with severe spasticity in physical rehabilitation and psychological aspects].
Topics: Activities of Daily Living; Adult; Baclofen; Cerebral Palsy; Child; Female; Follow-Up Studies; Hemip | 2007 |
Prolonged, severe intrathecal baclofen withdrawal syndrome: a case report.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Critical Care; Cross Infection; Device Removal; Dose-Re | 2007 |
Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; H | 2007 |
Cyproheptadine for pediatric intrathecal baclofen withdrawal: a case report.
Topics: Adolescent; Age Factors; Baclofen; Cerebral Palsy; Child; Cyproheptadine; Equipment Failure; Female; | 2007 |
Outcomes of posterior spinal fusion and instrumentation in patients with continuous intrathecal baclofen infusion pumps.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Female; Humans; Infusion Pumps, Implantable; Inj | 2008 |
Oral baclofen increases maximal voluntary neuromuscular activation of ankle plantar flexors in children with spasticity due to cerebral palsy.
Topics: Administration, Oral; Adolescent; Ankle Joint; Baclofen; Cerebral Palsy; Child; Child, Preschool; Do | 2008 |
Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales.
Topics: Adolescent; Baclofen; Caregivers; Cerebral Palsy; Child; Child, Preschool; Disability Evaluation; Dy | 2008 |
Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Cost-Benefit Analysis; Female; Humans; Injections, Spin | 2008 |
Intrathecal L-baclofen for cerebral spasticity: case report.
Topics: Adult; Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Male; Muscle Spasticity; Muscles | 1995 |
Cost analysis of continuous intrathecal baclofen versus selective functional posterior rhizotomy in the treatment of spastic quadriplegia associated with cerebral palsy.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Costs and Cost Analysis; Hospitalization; Humans; Injec | 1995 |
Staphylococcal meningitis following Synchromed intrathecal pump implant: a case report.
Topics: Adolescent; Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; | 1994 |
Continuous intrathecal baclofen infusion for spasticity of cerebral origin.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Infusion Pumps, Implan | 1993 |
Western medications needed in Lithuania.
Topics: Baclofen; Cerebral Palsy; Drugs, Generic; Female; Humans; Lithuania; USSR | 1993 |
Intrathecal baclofen for motor disorders.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Craniocerebral Trauma; Dystonia; Female; Humans; Inject | 1995 |
Effects of continuous intrathecal baclofen infusion and selective posterior rhizotomy on upper extremity spasticity.
Topics: Arm; Baclofen; Cerebral Palsy; Child; Humans; Infant, Newborn; Injections, Spinal; Leg; Muscle Relax | 1995 |
Continuous intrathecal baclofen infusion for symptomatic generalized dystonia.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Dose-Response Relationship, Drug; Dystonia; Fema | 1996 |
The management of cerebral palsy: subjectivity and a conundrum.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Sp | 1996 |
Baclofen in the treatment of cerebral palsy.
Topics: Administration, Oral; Baclofen; Cerebral Palsy; Drug Tolerance; Humans; Infusion Pumps; Injections, | 1996 |
New approaches to managing spasticity in children with cerebral palsy.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Humans; Injections, Spinal; Mus | 1997 |
Infusion of intrathecal baclofen for generalized dystonia in cerebral palsy.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Dystonia; Female; Humans; Inje | 1998 |
Effect on ambulation of continuous intrathecal baclofen infusion.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Crutches; Female; Follow-Up Stud | 1997 |
Patient management of cerebral origin spasticity with intrathecal baclofen.
Topics: Baclofen; Brain Injuries; Cerebral Palsy; Drug Monitoring; Hospital Units; Humans; Infusion Pumps, I | 1998 |
Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Contracture; Femur; Follow-Up | 1998 |
The effect of intrathecal baclofen on functional intelligibility of speech.
Topics: Adult; Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Speech | 1998 |
Intrathecal baclofen pump implantation complicated by epidural lipomatosis.
Topics: Adolescent; Baclofen; Cerebral Palsy; Epidural Space; Humans; Infusion Pumps, Implantable; Injection | 2000 |
Intrathecal baclofen withdrawal simulating neuroleptic malignant syndrome in a child with cerebral palsy.
Topics: Baclofen; Cerebral Palsy; Child; Diagnosis, Differential; Humans; Injections, Spinal; Male; Muscle R | 2000 |
Continuously infused intrathecal baclofen over 12 months for spastic hypertonia in adolescents and adults with cerebral palsy.
Topics: Adolescent; Adult; Analysis of Variance; Baclofen; Cerebral Palsy; Female; Humans; Infusion Pumps; I | 2001 |
Improvement of sleep apnea in a patient with cerebral palsy.
Topics: Adult; Baclofen; Cerebral Palsy; Dystonia; Female; Humans; Injections, Spinal; Muscle Spasticity; Po | 2001 |
Continuous intrathecal baclofen infusion for children with cerebral palsy: a pilot study.
Topics: Baclofen; Cerebral Palsy; Child; Drug Administration Schedule; Female; Humans; Injections, Spinal; M | 2001 |
Selective posterior rhizotomy and intrathecal baclofen for the treatment of spasticity.
Topics: Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Muscle Relaxants, Central; Quadriplegia; Rhizo | 2002 |
Recurrent intrathecal baclofen pump catheter leakage: A surgical observation with recommendations.
Topics: Baclofen; Catheterization; Cerebral Palsy; Child, Preschool; Equipment Failure; Equipment Failure An | 2002 |
Reversible coma in children after improper baclofen pump insertion.
Topics: Analgesics, Opioid; Baclofen; Cerebral Palsy; Child; Child, Preschool; Coma; Female; GABA Agonists; | 2002 |
Bacloffen (Lioresal) in the long-term management of spasticity.
Topics: Adolescent; Adult; Aged; Aminobutyrates; Baclofen; Cerebral Palsy; Child; Female; Humans; Long-Term | 1976 |
[Effect of lioresal on the rehabilitation of spastics].
Topics: Aminobutyrates; Baclofen; Cerebral Palsy; Humans; Muscle Spasticity; Spinal Cord Diseases | 1977 |
Chronic intrathecal baclofen administration in severe spasticity.
Topics: Adolescent; Adult; Baclofen; Brain Damage, Chronic; Cerebral Palsy; Female; Follow-Up Studies; Human | 1990 |
Intrathecal baclofen: not all spasticity is bad.
Topics: Baclofen; Cerebral Palsy; Humans; Muscle Spasticity | 1991 |
Intrathecal baclofen for cerebral spasticity.
Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Injections, Spinal; Muscle Sp | 1989 |