Page last updated: 2024-10-23

baclofen and Central Nervous System Disease

baclofen has been researched along with Central Nervous System Disease in 11 studies

Research Excerpts

ExcerptRelevanceReference
"We report the treatment of severe neuropathic pain in a patient with ED and the combined intrathecal application of baclofen and morphine in 5 patients with severe spasticity related pain."7.71Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain. ( Becker, R; Bertalanffy, H; Gatscher, S; Uhle, E, 2002)
"We report the treatment of severe neuropathic pain in a patient with ED and the combined intrathecal application of baclofen and morphine in 5 patients with severe spasticity related pain."3.71Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain. ( Becker, R; Bertalanffy, H; Gatscher, S; Uhle, E, 2002)
" They also required higher doses and more rapid dosage increases."2.68Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus. ( Dressnandt, J; Marquardt, G; Mauch, E; Meinck, HM; Müller-Schwefe, G; Rieke, K; Schumm, F; Stayer, C; Tronnier, V, 1997)
"Baclofen is a centrally-acting γ-amino butyric acid agonist used mainly in the symptomatic management of spasticity originating from the spinal cord."2.58Baclofen-induced neurotoxicity in patients with compromised renal function: Review. ( Achanti, A; Arany, I; Beck Gööz, M; Castaneda, J; Dreisbach, AW; Fülöp, T; Salim, SA; Thomas, L, 2018)
"To report the toxic effects of baclofen in patients with severely impaired renal function."2.40Baclofen toxicity in patients with severely impaired renal function. ( Bullard, MJ; Chen, KS; Chien, YY; Lee, SY, 1997)
"We studied the effects of GABA on anoxia-induced injury in CNS white matter using optic nerves exposed to 60 min of anoxia."1.29Endogenous GABA attenuates CNS white matter dysfunction following anoxia. ( Fern, R; Ransom, BR; Waxman, SG, 1995)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salim, SA1
Thomas, L1
Achanti, A1
Beck Gööz, M1
Castaneda, J1
Arany, I1
Dreisbach, AW1
Fülöp, T1
Taira, T1
Grabow, TS1
Christo, PJ1
Raja, SN1
Kerr, DI1
Ong, J1
Fern, R1
Waxman, SG1
Ransom, BR1
Chen, KS1
Bullard, MJ1
Chien, YY1
Lee, SY1
Stayer, C1
Tronnier, V1
Dressnandt, J1
Mauch, E1
Marquardt, G1
Rieke, K1
Müller-Schwefe, G1
Schumm, F1
Meinck, HM1
Leroy-Malherbe, V1
Laurent-Vannier, A1
Brugel, DG1
Urtizberea, JA1
Gatscher, S1
Becker, R1
Uhle, E1
Bertalanffy, H1
Halbhübner, K1
Herken, H1
Loos, D1
Young, RR1

Reviews

5 reviews available for baclofen and Central Nervous System Disease

ArticleYear
Baclofen-induced neurotoxicity in patients with compromised renal function: Review.
    International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:10

    Topics: Baclofen; Central Nervous System Diseases; Humans; Muscle Relaxants, Central; Renal Insufficiency

2018
Complex regional pain syndrome: diagnostic controversies, psychological dysfunction, and emerging concepts.
    Advances in psychosomatic medicine, 2004, Volume: 25

    Topics: Autonomic Nervous System Diseases; Baclofen; Caregivers; Central Nervous System Diseases; Combined M

2004
GABAB receptors.
    Pharmacology & therapeutics, 1995, Volume: 67, Issue:2

    Topics: Baclofen; Binding, Competitive; Cations, Divalent; Central Nervous System; Central Nervous System Di

1995
Baclofen toxicity in patients with severely impaired renal function.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:11

    Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Contraindications; Female; Humans; Kidney Fa

1997
[Recent progress in pediatric neurological rehabilitation].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Age Factors; Animals; Baclofen; Botulinum Toxins; Central Nervous System Diseases

2002

Trials

1 trial available for baclofen and Central Nervous System Disease

ArticleYear
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.
    Neurology, 1997, Volume: 49, Issue:6

    Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Cohort Studies; Disease Progression; Female;

1997

Other Studies

5 other studies available for baclofen and Central Nervous System Disease

ArticleYear
[Intrathecal baclofen therapy].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Baclofen; Central Nervous System Diseases; GABA-B Receptor Agonists; Humans; Infusion Pumps, Implant

2010
Endogenous GABA attenuates CNS white matter dysfunction following anoxia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:1 Pt 2

    Topics: Animals; Axons; Baclofen; Central Nervous System Diseases; Enzyme Activation; Female; gamma-Aminobut

1995
Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain.
    Acta neurochirurgica. Supplement, 2002, Volume: 79

    Topics: Afferent Pathways; Analgesics, Opioid; Baclofen; Central Nervous System Diseases; Denervation; Drug

2002
Experimental neuropathy with Parkinson-like muscular rigidity. A suitable model for testing dopaminergic agonists and neuroleptic drugs.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:10

    Topics: 6-Aminonicotinamide; Animals; Antipsychotic Agents; Baclofen; Brain; Brain Chemistry; Bromocriptine;

1978
The physiology of spasticity and its response to therapy.
    Annals of the New York Academy of Sciences, 1988, Volume: 531

    Topics: Animals; Baclofen; Central Nervous System Diseases; Dantrolene; Diazepam; Humans; Motor Neurons; Mus

1988