Page last updated: 2024-10-23

baclofen and Cannabis Abuse

baclofen has been researched along with Cannabis Abuse in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nanjayya, SB1
Shivappa, M1
Chand, PK1
Murthy, P1
Benegal, V1
Haney, M1
Hart, CL1
Vosburg, SK1
Comer, SD1
Reed, SC1
Cooper, ZD1
Foltin, RW1
Lile, JA1
Kelly, TH1
Hays, LR1
Varvel, SA1
Anum, E1
Niyuhire, F1
Wise, LE1
Lichtman, AH1
Kaplan, GB1
McRoberts, RL1
Smokler, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Baclofen on Marijuana Withdrawal and Relapse[NCT00373295]Phase 213 participants (Actual)Interventional2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Measure of Relapse: Change in Money Spent Between Baseline and Relapse Phase

"This is a measure of marijuana self-administration and relapse since each initial puff costs $7 and is a burden to overcome just to smoke.~Over each 3 day period, the puffs chosen by each participant is averaged for a single value." (NCT00373295)
Timeframe: Days 1-3 (Baseline) and Days 6-8 (Relapse Phase)

Interventiondollars spent on marijuana (Mean)
Baclofen 60, Marijuana7.15
Placebo, Marijuana9.77
Baclofen 90, Marijuana7.25

Trials

1 trial available for baclofen and Cannabis Abuse

ArticleYear
Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse.
    Psychopharmacology, 2010, Volume: 211, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Affect; Baclofen; Cognition; Dose-Response Relationship, Drug;

2010

Other Studies

4 other studies available for baclofen and Cannabis Abuse

ArticleYear
Baclofen in cannabis dependence syndrome.
    Biological psychiatry, 2010, Aug-01, Volume: 68, Issue:3

    Topics: Adult; Baclofen; GABA-B Receptor Agonists; Humans; Male; Marijuana Abuse; Secondary Prevention; Subs

2010
Separate and combined effects of the GABA(B) agonist baclofen and Δ9-THC in humans discriminating Δ9-THC.
    Drug and alcohol dependence, 2012, Nov-01, Volume: 126, Issue:1-2

    Topics: Adolescent; Adult; Baclofen; Blood Pressure; Body Temperature; Body Temperature Regulation; Demograp

2012
Delta(9)-THC-induced cognitive deficits in mice are reversed by the GABA(A) antagonist bicuculline.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Animals; Baclofen; Bicuculline; Brain; Dronabinol; GABA-A Receptor Agonists; GABA-A Receptor Antagon

2005
Baclofen as adjunctive treatment for a patient with cocaine dependence and schizoaffective disorder.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: Alcoholism; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Baclofen; Bipolar Disord

2004