Page last updated: 2024-10-23
baclofen and Cancer of Endometrium
baclofen has been researched along with Cancer of Endometrium in 1 studies
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Kroin, JS | 1 |
| Ali, A | 1 |
| York, M | 1 |
| Penn, RD | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Intrathecal (IT) Baclofen Drug Distribution Pilot Study[NCT02903823] | Phase 4 | 27 participants (Actual) | Interventional | 2016-04-22 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
Subjects Experiencing Maximal MAS Change From Baseline - Spasticity of Cerebral Origin
"The Modified Ashworth Scale (MAS) is a 6-point scale (Standard MAS scale values: 0, 1, 1.5, 2, 3, or 4) used to evaluate spasticity based on grading muscle tone by moving joints. The MAS scores in this cohort are measured in biceps, triceps and forearm flexor muscles in upper extremities; and quadriceps, hamstrings and gastrocnemius muscles in lower extremities. The score ranges from 0 (no increase in muscle tone) to 4 (affected part(s) rigid in flexion or extension). Improvement in spasticity was a reduction in MAS score by 1 point across a joint tested. Maximal MAS change is the sum of MAS score reduction in all four limbs tested.~This outcome looks at subjects with spasticity of cerebral origin." (NCT02903823)
Timeframe: Baseline to 6 hours post-injection
| Intervention | Participants (Count of Participants) |
|---|
| Cervical level 4 injection site | Thoracic level 3 injection site | Thoracic level 10 injection site | Lumbar lever 2 injection site |
|---|
| Subjects With Max MAS Change | 8 | 7 | 3 | 3 |
Subjects Experiencing Maximal MAS Change From Baseline - Spasticity of Spinal Origin
"The Modified Ashworth Scale (MAS) is a 6-point scale (Standard MAS scale values: 0, 1, 1.5, 2, 3, or 4) used to evaluate spasticity based on grading muscle tone by moving joints. The MAS scores in this cohort are measured in biceps, triceps and forearm flexor muscles in upper extremities; and quadriceps, hamstrings and gastrocnemius muscles in lower extremities. The score ranges from 0 (no increase in muscle tone) to 4 (affected part(s) rigid in flexion or extension). Improvement in spasticity was a reduction in MAS score by 1 point across a joint tested. Maximal MAS change is the sum of MAS score reduction in all four limbs tested.~This outcome looks at subjects with spasticity of spinal origin." (NCT02903823)
Timeframe: Baseline to 6 hours post-injection
| Intervention | Participants (Count of Participants) |
|---|
| Cervical spine level 4 injection site | Thoracic level 3 injection site | Thoracic level 10 injection site | Lumbar level 2 injection site |
|---|
| Subjects With MAS Change - Based on Site of Injection | 4 | 2 | 5 | 3 |
Other Studies
1 other study available for baclofen and Cancer of Endometrium