baclofen has been researched along with Brain Injuries in 59 studies
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe the long-term disorders of consciousness in patients with dysautonomia and hypertonia treated with intrathecal baclofen therapy (IBT)." | 7.78 | A 10-year follow-up study of patients with severe traumatic brain injury and dysautonomia treated with intrathecal baclofen therapy. ( Cuny, E; Dehail, P; Hoarau, X; Richer, E, 2012) |
| "To compare the long-term outcome of patients with severe traumatic brain injury and patients with hypoxic brain injury with dysautonomia and hypertonia treated with intrathecal baclofen therapy." | 7.78 | Comparison of long-term outcomes of patients with severe traumatic or hypoxic brain injuries treated with intrathecal baclofen therapy for dysautonomia. ( Cuny, E; Dehail, P; Hoarau, X; Richer, E, 2012) |
| "To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia." | 7.72 | Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003) |
| "Change of spasticity was evaluated using the Modified Ashworth Scale." | 5.46 | Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury. ( Chae, M; Chang, JW; Chang, WS; Cho, HE; Cho, SR; Lee, KC; Yoon, YK, 2017) |
| "Although excessive weight gain is not a common problem in children with cerebral origin spasticity, increased weight-gain velocity is prevalent in children receiving ITB therapy." | 5.33 | Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy. ( Ayyangar, RN; Fox, MA; McCoy, AA; Schaubel, DE, 2006) |
| "To evaluate long-term results of chronic intrathecal Baclofen infusion on the spasticity, on the spasms and to evaluate the side-effects of the intrathecal Baclofen in patients with supraspinal spasticity." | 5.10 | Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood. ( Bono, G; Casagrande, F; Dario, A; Di Stefano, MG; Grossi, A, 2002) |
| "Continuous intrathecal infusion of baclofen is capable of maintaining a reduction in spasticity and dystonia in both the upper and lower extremities of TBI patients." | 5.09 | Long-term continuously infused intrathecal baclofen for spastic-dystonic hypertonia in traumatic brain injury: 1-year experience. ( Grabb, P; Guin-Renfroe, S; Hadley, MN; Meythaler, JM, 1999) |
| " This study examines the value of intrathecally administered baclofen in the treatment of 19 children with severe spasticity of cerebral origin: eight of whom sustained brain injury associated with trauma, near drowning, or cardiac arrest; 10 with cerebral palsy (spastic quadriplegia); and one child with Leigh's disease." | 5.08 | Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin. ( Armstrong, RW; Cochrane, DD; Farrell, K; Fife, SE; Kube, SD; Steinbok, P, 1997) |
| "Intrathecal baclofen therapy, given via an implanted pump in the abdominal wall either as a continuous infusion or bolus dosing, has been used for more than 25 years to treat the spasticity and dystonia associated with various brain and spinal cord conditions." | 4.95 | Baclofen Pumps: Uses and Complications. ( Baum, CR; Woolf, SM, 2017) |
| "To describe the long-term disorders of consciousness in patients with dysautonomia and hypertonia treated with intrathecal baclofen therapy (IBT)." | 3.78 | A 10-year follow-up study of patients with severe traumatic brain injury and dysautonomia treated with intrathecal baclofen therapy. ( Cuny, E; Dehail, P; Hoarau, X; Richer, E, 2012) |
| "To compare the long-term outcome of patients with severe traumatic brain injury and patients with hypoxic brain injury with dysautonomia and hypertonia treated with intrathecal baclofen therapy." | 3.78 | Comparison of long-term outcomes of patients with severe traumatic or hypoxic brain injuries treated with intrathecal baclofen therapy for dysautonomia. ( Cuny, E; Dehail, P; Hoarau, X; Richer, E, 2012) |
| "Intrathecal baclofen (ITB) therapy is widely used in the management of spastic hypertonia and dystonia resulting from a multitude of conditions that present with upper motor neuron syndrome signs, such as cerebral palsy, stroke, brain and spinal injuries, and multiple sclerosis." | 3.73 | Successful treatment of posttraumatic hemiballismus with intrathecal baclofen therapy. ( Francisco, GE, 2006) |
| "To determine whether leg muscle stiffness is measurably reduced after intrathecal baclofen (ITB) in subjects with spastic hemiplegia." | 3.72 | Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. ( Bouilland, S; Bussel, B; Rémy-Néris, O; Tiffreau, V, 2003) |
| "Intrathecal baclofen (ITB) infusion has been shown to be an effective treatment for spasticity secondary to both cerebral palsy and spinal cord injury." | 3.69 | Effect on ambulation of continuous intrathecal baclofen infusion. ( Albright, AL; Barry, MJ; Gerszten, PC, 1997) |
| "Adults (N=28) with muscle hypertonia due to stroke, trauma, or anoxia." | 2.75 | Effect of intrathecal baclofen bolus injection on lower extremity joint range of motion during gait in patients with acquired brain injury. ( Chow, JW; Horn, TS; Lee, JE; Stokic, DS; Yablon, SA, 2010) |
| "Walking performance and spasticity in lower-extremity muscles were assessed before and at 2, 4, and 6 hours after ITB bolus injection." | 2.71 | Effect of intrathecal baclofen bolus injection on temporospatial gait characteristics in patients with acquired brain injury. ( Horn, TS; Stokic, DS; Yablon, SA, 2005) |
| "Eighteen patients with severe spasticity of cerebral origin, who failed to respond adequately to more conservative treatments, have-been treated with continuous infusion of intrathecal baclofen delivered via an implanted pump." | 2.69 | Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients. ( Rawicki, B, 1999) |
| "Severe spinal spasticity has been shown to be a good indication for continuous intrathecal baclofen infusion (CIBI), but there is only limited experience with this treatment in patients with supraspinal spasticity." | 2.68 | Continuous intrathecal baclofen infusion in severe spasticity after traumatic or hypoxic brain injury. ( Alberti, O; Bauer, BL; Becker, R, 1997) |
| "Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties." | 2.58 | Interventions for eye movement disorders due to acquired brain injury. ( Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ, 2018) |
| "Between 30% and 50% of survivors of cardiac arrest (CA) suffer from cognitive deficits." | 1.72 | Baclofen attenuates cognitive deficits in post-cardiac arrest brain injury. ( Chen, X; Cong, T; Li, J; Li, L; Sun, Y; Wu, H; Xiao, Z; Zhou, Y, 2022) |
| "Change of spasticity was evaluated using the Modified Ashworth Scale." | 1.46 | Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury. ( Chae, M; Chang, JW; Chang, WS; Cho, HE; Cho, SR; Lee, KC; Yoon, YK, 2017) |
| "Significant differences in dosing were found between diagnoses and trended to differ by ambulatory status at the end of the study, and similar trends could be observed in achieving initial stable dose." | 1.43 | Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review. ( Clearfield, JS; McGuire, J; Nelson, ME; Rein, LE; Tarima, S, 2016) |
| " Data studied included baseline demographic and injury variables, implantation data, spasticity and function, ITB dosage over time and complications." | 1.43 | Treatment of severe, disabling spasticity with continuous intrathecal baclofen therapy following acquired brain injury: the experience of a tertiary institution in Singapore. ( Chua, KS; King, NK; Law, JH; Ng, WH; Rajeswaran, DK; Rao, JP; Soh, S; Wang, ZM, 2016) |
| "ITB lessens the degree of spasticity which in turn facilitates care and, thus, has the potential to limit contractures." | 1.42 | Influence of intrathecal baclofen on the level of consciousness and mental functions after extremely severe traumatic brain injury: brief report. ( Al-Khodairy, AT; Nicolo, D; Vuadens, P; Wicky, G, 2015) |
| "05), while baclofen dosage increased (p = 0." | 1.40 | Intrathecal baclofen therapy in children with severe spasticity: Outcome and complications. ( Altermatt, S; Furrer, C; Meyer-Heim, A; Walter, M, 2014) |
| "Reduction of spasticity and spasms frequency were measured 3 months after patients received the implant and at the 1-year follow-up." | 1.39 | Timing of intrathecal baclofen therapy in persons with acquired brain injury: influence on outcome. ( Bordi, L; Calandriello, B; Galli, R; Iardella, L; Logi, F; Posteraro, F, 2013) |
| "In addition to spasticity, TBI patients exhibit enduring cognitive, balance, and other motor impairments." | 1.39 | Effects of acute intrathecal baclofen in an animal model of TBI-induced spasticity, cognitive, and balance disabilities. ( Bose, P; Hou, J; Keener, J; Nelson, R; Nissim, N; Parmer, R; Thompson, FJ; Wacnik, PW, 2013) |
| " The severity of spasticity as a consequence of brain injury can change during years and it is necessery to follow it with dosage and dynamics of baclofen therapy." | 1.38 | [Results of intrathecal baclofen therapy on spasticity in patients with brain injury]. ( Both, B; Dénes, Z; Klauber, A; Lóránd, E, 2012) |
| "Cortical and spinal spasticity appear to parallel each other with no significant differences in daily dosing, dosing changes, and mode of delivery of intrathecal baclofen." | 1.36 | Intrathecal baclofen for spasticity management: a comparative analysis of spasticity of spinal vs cortical origin. ( Chiodo, AE; Saval, A, 2010) |
| " There are few published guidelines for dosing efficacy and no studies looking at the effect of concentration of ITB on spasticity management." | 1.35 | Effect of intrathecal baclofen concentration on spasticity control: case series. ( Chiodo, AE; Saval, A, 2008) |
| "Recurrent respiratory tract infections and occasional decubitus required periodic hospitalizations." | 1.35 | [Comprehensive management of a child with a post-traumatic brain stem and spinal cord injury. A case study and presentation of current therapeutic modalities]. ( Inglot, B; Kobylarz, K; Kwiatkowski, S; Mróz, A, 2008) |
| "Although excessive weight gain is not a common problem in children with cerebral origin spasticity, increased weight-gain velocity is prevalent in children receiving ITB therapy." | 1.33 | Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy. ( Ayyangar, RN; Fox, MA; McCoy, AA; Schaubel, DE, 2006) |
| "Duration postinjury and location of spasticity were the most predictive variables for clonidine dosage as a model (r = ." | 1.33 | Oral baclofen and clonidine for treatment of spasticity in children. ( Haase, M; Habersang, R; Lubsch, L; Luedtke, S, 2006) |
| "These patients suffered severe spasticity from a number of disease processes including multiple sclerosis, cerebral palsy, and brain injury." | 1.32 | Intrathecal baclofen therapy over 10 years. ( Rawlins, PK, 2004) |
| "Twelve consecutive patients with severe spasticity and hypertonia following acquired brain injury were treated with continuous intrathecal infusion of baclofen via an implanted, programmable infusion pump-catheter system for a minimum of 3 months." | 1.30 | Prospective assessment of continuous intrathecal infusion of baclofen for spasticity caused by acquired brain injury: a preliminary report. ( Hadley, MN; McCary, A; Meythaler, JM, 1997) |
| "In 14 patients, contractures caused by spasticity were successfully treated with plaster casts, which were changed weekly." | 1.28 | [Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma]. ( Frischhut, B; Saltuari, L, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.69) | 18.7374 |
| 1990's | 12 (20.34) | 18.2507 |
| 2000's | 21 (35.59) | 29.6817 |
| 2010's | 22 (37.29) | 24.3611 |
| 2020's | 3 (5.08) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 1 |
| Cong, T | 1 |
| Li, L | 1 |
| Li, J | 1 |
| Wu, H | 1 |
| Chen, X | 1 |
| Zhou, Y | 1 |
| Xiao, Z | 1 |
| Park, JY | 1 |
| Park, J | 1 |
| Baek, J | 1 |
| Chang, JW | 2 |
| Kim, YG | 1 |
| Chang, WS | 2 |
| O'Keefe, LM | 1 |
| Mui, G | 1 |
| Chow, JW | 3 |
| Yablon, SA | 5 |
| Stokic, DS | 5 |
| Woolf, SM | 1 |
| Baum, CR | 1 |
| De Tanti, A | 1 |
| Scarponi, F | 1 |
| Bertoni, M | 1 |
| Gasperini, G | 1 |
| Lanzillo, B | 1 |
| Molteni, F | 1 |
| Posteraro, F | 2 |
| Vitale, DF | 1 |
| Zanpolini, M | 1 |
| Yoon, YK | 1 |
| Lee, KC | 1 |
| Cho, HE | 1 |
| Chae, M | 1 |
| Cho, SR | 1 |
| Rowe, FJ | 1 |
| Hanna, K | 1 |
| Evans, JR | 1 |
| Noonan, CP | 1 |
| Garcia-Finana, M | 1 |
| Dodridge, CS | 1 |
| Howard, C | 1 |
| Jarvis, KA | 1 |
| MacDiarmid, SL | 1 |
| Maan, T | 1 |
| North, L | 1 |
| Rodgers, H | 1 |
| Walter, M | 2 |
| Altermatt, S | 2 |
| Furrer, C | 2 |
| Meyer-Heim, A | 2 |
| Calandriello, B | 1 |
| Galli, R | 1 |
| Logi, F | 1 |
| Iardella, L | 1 |
| Bordi, L | 1 |
| Al-Khodairy, AT | 1 |
| Wicky, G | 1 |
| Nicolo, D | 1 |
| Vuadens, P | 1 |
| Clearfield, JS | 1 |
| Nelson, ME | 1 |
| McGuire, J | 1 |
| Rein, LE | 1 |
| Tarima, S | 1 |
| Dekopov, AV | 1 |
| Shabalov, VA | 1 |
| Tomskiy, AA | 1 |
| Gaevyi, IO | 1 |
| Salova, EM | 1 |
| Wang, ZM | 1 |
| Law, JH | 1 |
| King, NK | 1 |
| Rajeswaran, DK | 1 |
| Soh, S | 1 |
| Rao, JP | 1 |
| Ng, WH | 1 |
| Chua, KS | 1 |
| Kobylarz, K | 1 |
| Kwiatkowski, S | 1 |
| Inglot, B | 1 |
| Mróz, A | 1 |
| Saval, A | 2 |
| Chiodo, AE | 2 |
| Matsuda, R | 1 |
| Nishimura, F | 1 |
| Hirabayashi, H | 1 |
| Motoyama, Y | 1 |
| Mishima, H | 1 |
| Park, YS | 1 |
| Nakase, H | 1 |
| Sakaki, T | 1 |
| Horn, TS | 2 |
| Lee, JE | 1 |
| Haranhalli, N | 1 |
| Anand, D | 1 |
| Wisoff, JH | 1 |
| Harter, DH | 1 |
| Weiner, HL | 1 |
| Blate, M | 1 |
| Roth, J | 1 |
| Pangilinan, PH | 1 |
| Giacoletti-Argento, A | 1 |
| Shellhaas, R | 1 |
| Hurvitz, EA | 1 |
| Hornyak, JE | 1 |
| Hoarau, X | 2 |
| Richer, E | 3 |
| Dehail, P | 2 |
| Cuny, E | 4 |
| Turner, M | 1 |
| Nguyen, HS | 1 |
| Cohen-Gadol, AA | 1 |
| Dénes, Z | 1 |
| Klauber, A | 1 |
| Both, B | 1 |
| Lóránd, E | 1 |
| Bose, P | 1 |
| Hou, J | 1 |
| Nelson, R | 1 |
| Nissim, N | 1 |
| Parmer, R | 1 |
| Keener, J | 1 |
| Wacnik, PW | 1 |
| Thompson, FJ | 1 |
| Rémy-Néris, O | 1 |
| Tiffreau, V | 1 |
| Bouilland, S | 1 |
| Bussel, B | 1 |
| Turner, MS | 1 |
| Gooch, JL | 1 |
| Oberg, WA | 1 |
| Grams, B | 1 |
| Ward, LA | 1 |
| Walker, ML | 1 |
| Rawlins, PK | 1 |
| Francisco, GE | 2 |
| Hu, MM | 1 |
| Boake, C | 1 |
| Ivanhoe, CB | 1 |
| Baguley, IJ | 1 |
| Bailey, KM | 1 |
| Slewa-Younan, S | 1 |
| Hayes, A | 1 |
| McCoy, AA | 1 |
| Fox, MA | 1 |
| Schaubel, DE | 1 |
| Ayyangar, RN | 1 |
| Lubsch, L | 1 |
| Habersang, R | 1 |
| Haase, M | 1 |
| Luedtke, S | 1 |
| Taira, T | 1 |
| Ochiai, T | 1 |
| Goto, S | 1 |
| Hori, T | 1 |
| Kofler, M | 3 |
| Kronenberg, MF | 1 |
| Rifici, C | 2 |
| Saltuari, L | 4 |
| Bauer, G | 1 |
| Meythaler, JM | 3 |
| DeVivo, MJ | 1 |
| Hadley, M | 1 |
| Becker, R | 2 |
| Alberti, O | 1 |
| Bauer, BL | 1 |
| Armstrong, RW | 1 |
| Steinbok, P | 1 |
| Cochrane, DD | 1 |
| Kube, SD | 1 |
| Fife, SE | 1 |
| Farrell, K | 1 |
| McCary, A | 1 |
| Hadley, MN | 2 |
| Gerszten, PC | 1 |
| Albright, AL | 1 |
| Barry, MJ | 1 |
| Rawlins, P | 1 |
| Guin-Renfroe, S | 1 |
| Grabb, P | 1 |
| Rawicki, B | 1 |
| Benes, L | 1 |
| Sure, U | 1 |
| Hellwig, D | 1 |
| Bertalanffy, H | 1 |
| François, B | 1 |
| Vacher, P | 1 |
| Roustan, J | 1 |
| Salle, JY | 1 |
| Vidal, J | 1 |
| Moreau, JJ | 1 |
| Vignon, P | 1 |
| Castel, JP | 1 |
| Elovic, E | 1 |
| Dario, A | 1 |
| Di Stefano, MG | 1 |
| Grossi, A | 1 |
| Casagrande, F | 1 |
| Bono, G | 1 |
| Frischhut, B | 1 |
| Kronenberg, M | 1 |
| Marosi, MJ | 1 |
| Russegger, L | 1 |
| Bramanti, P | 1 |
| Gerstenbrand, F | 2 |
| Fodstad, H | 1 |
| Ljunggren, BC | 1 |
| Schmutzhard, E | 1 |
| Baumgartner, H | 1 |
| Aichner, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance[NCT06067607] | 10 participants (Anticipated) | Interventional | 2023-02-01 | Recruiting | |||
| Controlling Hyperadrenergic Activity in Neurologic Injury[NCT01343329] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to Unable to enroll subjects that fit study criteria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for baclofen and Brain Injuries
| Article | Year |
|---|---|
Baclofen Pumps: Uses and Complications.
Topics: Baclofen; Brain Injuries; Dystonia; Humans; Infusion Pumps, Implantable; Reoperation; Spinal Cord In | 2017 |
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain I | 2018 |
Neuropharmacology in pediatric brain injury: a review.
Topics: Adolescent; Adrenergic beta-Antagonists; Anticonvulsants; Antidepressive Agents; Antipsychotic Agent | 2010 |
[Intrathecal baclofen and traumatic brain injury. A review].
Topics: Baclofen; Brain Injuries; GABA Agonists; Humans; Injections, Spinal; Muscle Relaxants, Central | 2003 |
Principles of pharmaceutical management of spastic hypertonia.
Topics: Anti-Dyskinesia Agents; Baclofen; Benzodiazepines; Botulinum Toxins; Brain Injuries; Clonidine; Dant | 2001 |
10 trials available for baclofen and Brain Injuries
| Article | Year |
|---|---|
Intrathecal baclofen bolus reduces exaggerated extensor coactivation during pre-swing and early-swing of gait after acquired brain injury.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Female; Gait; Humans; Male; Middle Aged; Muscle Relaxan | 2017 |
Effect of intrathecal baclofen bolus injection on lower extremity joint range of motion during gait in patients with acquired brain injury.
Topics: Adult; Ankle Joint; Baclofen; Brain Injuries; Female; Gait; Hip Joint; Humans; Injections, Spinal; J | 2010 |
Effect of intrathecal baclofen bolus injection on temporospatial gait characteristics in patients with acquired brain injury.
Topics: Adult; Baclofen; Brain Injuries; Computers; Female; Gait Disorders, Neurologic; Humans; Injections, | 2005 |
Prospective study on the use of bolus intrathecal baclofen for spastic hypertonia due to acquired brain injury.
Topics: Adult; Baclofen; Brain Injuries; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections | 1996 |
Continuous intrathecal baclofen infusion in severe spasticity after traumatic or hypoxic brain injury.
Topics: Adult; Aged; Baclofen; Brain Injuries; Dose-Response Relationship, Drug; Female; Humans; Hypoxia, Br | 1997 |
Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin.
Topics: Adolescent; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Humans; Infusion Pump | 1997 |
Long-term continuously infused intrathecal baclofen for spastic-dystonic hypertonia in traumatic brain injury: 1-year experience.
Topics: Adolescent; Adult; Analysis of Variance; Baclofen; Brain Injuries; Child; Dose-Response Relationship | 1999 |
Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Dystonia Musculorum Deformans; Follow-U | 1999 |
Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Female; Glasgow Outcome Scale; Humans; Hypoxia, Brain; | 2002 |
Long-term intrathecal baclofen treatment in supraspinal spasticity.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Humans; Infusion Pumps; Injections, Spinal; Male; M | 1992 |
44 other studies available for baclofen and Brain Injuries
| Article | Year |
|---|---|
Baclofen attenuates cognitive deficits in post-cardiac arrest brain injury.
Topics: Animals; Baclofen; Brain Injuries; Cognition; Heart Arrest; Inflammasomes; NLR Family, Pyrin Domain- | 2022 |
Long-term results on the suppression of secondary brain injury by early administered low-dose baclofen in a traumatic brain injury mouse model.
Topics: Animals; Baclofen; Brain Injuries; Brain Injuries, Traumatic; Disease Models, Animal; Humans; Mice; | 2023 |
Treating Paroxysmal Sympathetic Hyperactivity With Enteral Baclofen in Anoxic Brain Injury.
Topics: Autonomic Nervous System Diseases; Baclofen; Brain Injuries; Female; Hospitalization; Humans; Length | 2020 |
Management of intrathecal baclofen therapy for severe acquired brain injury: consensus and recommendations for good clinical practice.
Topics: Baclofen; Brain Injuries; Clinical Trials as Topic; Female; Humans; Injections, Spinal; Male; Muscle | 2017 |
Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Female; Humans; Infusion Pumps, Implantable; Inject | 2017 |
Intrathecal baclofen therapy in children with severe spasticity: Outcome and complications.
Topics: Adolescent; Baclofen; Brain Diseases; Brain Injuries; Child; Child, Preschool; Female; Follow-Up Stu | 2014 |
Timing of intrathecal baclofen therapy in persons with acquired brain injury: influence on outcome.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Dose-Response Relationship, Drug; Drug Administration S | 2013 |
Effect of intrathecal baclofen bolus injection on ankle muscle activation during gait in patients with acquired brain injury.
Topics: Adolescent; Adult; Ankle; Baclofen; Biomechanical Phenomena; Brain Injuries; Electromyography; Femal | 2015 |
Intrathecal baclofen therapy in children with acquired brain injuries after drowning: A case series.
Topics: Baclofen; Brain Injuries; Child; Child, Preschool; Female; Humans; Injections, Spinal; Male; Muscle | 2015 |
Influence of intrathecal baclofen on the level of consciousness and mental functions after extremely severe traumatic brain injury: brief report.
Topics: Adult; Baclofen; Brain Injuries; Consciousness; Humans; Male; Mental Processes; Middle Aged; Muscle | 2015 |
Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review.
Topics: Adult; Aged; Baclofen; Brain Injuries; Cerebral Palsy; Dose-Response Relationship, Drug; Female; Hum | 2016 |
[Preliminary results of chronic intrathecal therapy in treatment of spastic syndromes of various etiologies].
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Humans; Infusions, Spinal; Muscle Relaxants, | 2015 |
Treatment of severe, disabling spasticity with continuous intrathecal baclofen therapy following acquired brain injury: the experience of a tertiary institution in Singapore.
Topics: Baclofen; Brain Injuries; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infus | 2016 |
[Comprehensive management of a child with a post-traumatic brain stem and spinal cord injury. A case study and presentation of current therapeutic modalities].
Topics: Baclofen; Brain Injuries; Brain Stem; Cervical Vertebrae; Child; Drug Resistance; Humans; Infusion P | 2008 |
Effect of intrathecal baclofen concentration on spasticity control: case series.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Female; GABA Agonists; Humans; Infusion Pumps; Inje | 2008 |
[Case report of intrathecal baclofen administration in a child with severe spasticity attributable to traumatic brain injury].
Topics: Adolescent; Baclofen; Brain Injuries; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; | 2009 |
Intrathecal baclofen for spasticity management: a comparative analysis of spasticity of spinal vs cortical origin.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Botulinum Toxins, Type A; Brain Injuries; Cerebral Cortex; | 2010 |
Intrathecal baclofen therapy: complication avoidance and management.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Equipment Fail | 2011 |
A 10-year follow-up study of patients with severe traumatic brain injury and dysautonomia treated with intrathecal baclofen therapy.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Child; Drug Administration Schedule; Female; Follow-Up | 2012 |
Comparison of long-term outcomes of patients with severe traumatic or hypoxic brain injuries treated with intrathecal baclofen therapy for dysautonomia.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Child; Drug Administration Schedule; Female; Follow-Up | 2012 |
Intraventricular baclofen as an alternative to intrathecal baclofen for intractable spasticity or dystonia: outcomes and technical considerations.
Topics: Adolescent; Adult; Aged; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Dystonic | 2012 |
[Results of intrathecal baclofen therapy on spasticity in patients with brain injury].
Topics: Adult; Baclofen; Brain Injuries; Drug Administration Schedule; Female; Humans; Hungary; Infusion Pum | 2012 |
Effects of acute intrathecal baclofen in an animal model of TBI-induced spasticity, cognitive, and balance disabilities.
Topics: Animals; Baclofen; Behavior, Animal; Brain Injuries; Cognition; Disease Models, Animal; Evoked Poten | 2013 |
Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait.
Topics: Adult; Ankle; Baclofen; Biomechanical Phenomena; Body Weight; Brain Injuries; Cerebral Palsy; Electr | 2003 |
Early use of intrathecal baclofen in brain injury in pediatric patients.
Topics: Adolescent; Autonomic Nervous System Diseases; Baclofen; Brain Injuries; Child; Child, Preschool; Fe | 2003 |
Care provider assessment of intrathecal baclofen in children.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Female; Humans | 2004 |
Intrathecal baclofen therapy over 10 years.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Drug Implants; | 2004 |
Efficacy of early use of intrathecal baclofen therapy for treating spastic hypertonia due to acquired brain injury.
Topics: Adolescent; Adult; Aged; Baclofen; Brain Injuries; Child; Disability Evaluation; Drug Delivery Syste | 2005 |
Prolonged anti-spasticity effects of bolus intrathecal baclofen.
Topics: Adult; Baclofen; Brain Injuries; Electromyography; Humans; Injections, Spinal; Male; Muscle Relaxant | 2005 |
Comparison of clinical and neurophysiologic responses to intrathecal baclofen bolus administration in moderate-to-severe spasticity after acquired brain injury.
Topics: Adolescent; Adult; Analysis of Variance; Baclofen; Brain Injuries; Dose-Response Relationship, Drug; | 2005 |
Successful treatment of posttraumatic hemiballismus with intrathecal baclofen therapy.
Topics: Adult; Baclofen; Brain Injuries; Dyskinesias; Dystonia; Humans; Infusion Pumps, Implantable; Injecti | 2006 |
Weight gain in children with hypertonia of cerebral origin receiving intrathecal baclofen therapy.
Topics: Adolescent; Baclofen; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Female; Hospitals, Pe | 2006 |
Oral baclofen and clonidine for treatment of spasticity in children.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Age Factors; Baclofen; Brain Inj | 2006 |
Fifteen year experience of intrathecal baclofen treatment in Japan.
Topics: Baclofen; Brain Injuries; Child; Humans; Injections, Spinal; Japan; Male; Muscle Relaxants, Central; | 2006 |
Epileptic seizures associated with intrathecal baclofen application.
Topics: Adolescent; Adult; Anticonvulsants; Baclofen; Brain Injuries; Epilepsy; Humans; Infusion Pumps, Impl | 1994 |
Prospective assessment of continuous intrathecal infusion of baclofen for spasticity caused by acquired brain injury: a preliminary report.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Female; Humans; Infusions, Parenteral; Injections, Spin | 1997 |
Effect on ambulation of continuous intrathecal baclofen infusion.
Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Child; Crutches; Female; Follow-Up Stud | 1997 |
Patient management of cerebral origin spasticity with intrathecal baclofen.
Topics: Baclofen; Brain Injuries; Cerebral Palsy; Drug Monitoring; Hospital Units; Humans; Infusion Pumps, I | 1998 |
Intrathecal baclofen alleviates autonomic dysfunction in severe brain injury.
Topics: Adult; Animals; Autonomic Dysreflexia; Autonomic Nervous System; Baclofen; Brain; Brain Injuries; Hu | 2000 |
Intrathecal baclofen after traumatic brain injury: early treatment using a new technique to prevent spasticity.
Topics: Adult; Autonomic Nervous System Diseases; Baclofen; Brain Injuries; Child; Female; GABA Agonists; Hu | 2001 |
Dysautonomia syndrome in the acute recovery phase after traumatic brain injury: relief with intrathecal Baclofen therapy.
Topics: Acute Disease; Adolescent; Adult; Autonomic Nervous System Diseases; Baclofen; Brain Injuries; GABA | 2001 |
[Treatment concepts of tertiary damage of the locomotor system after craniocerebral trauma].
Topics: Anesthetics, Local; Baclofen; Brain Damage, Chronic; Brain Injuries; Catheters, Indwelling; Combined | 1992 |
Baclofen and carbamazepine in supraspinal spasticity.
Topics: Administration, Oral; Adult; Baclofen; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Fem | 1991 |
Intrathecal baclofen for intractable spasticity due to severe brain injury.
Topics: Adult; Baclofen; Brain Injuries; Chronic Disease; Dose-Response Relationship, Drug; Humans; Injectio | 1989 |