baclofen has been researched along with Bradyarrhythmia in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a unique case of intrathecal baclofen overdose mimicking brainstem death, during bilateral anterior cingulate cortex deep brain stimulation (DBS) for pain." | 8.12 | Intrathecal baclofen overdose mimicking brainstem death during deep brain stimulation surgery for pain. ( Alamri, A; Aziz, T; Mostofi, A; Pereira, E, 2022) |
| "We describe a 6 year-old girl with hydranencephaly who underwent an intrathecal baclofen test dose and developed severe bradycardia." | 7.81 | Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly. ( Cain, N; Kinsman, S; Sechrist, C, 2015) |
| "The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug." | 7.78 | Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012) |
| "We describe a unique case of intrathecal baclofen overdose mimicking brainstem death, during bilateral anterior cingulate cortex deep brain stimulation (DBS) for pain." | 4.12 | Intrathecal baclofen overdose mimicking brainstem death during deep brain stimulation surgery for pain. ( Alamri, A; Aziz, T; Mostofi, A; Pereira, E, 2022) |
| "We describe a 6 year-old girl with hydranencephaly who underwent an intrathecal baclofen test dose and developed severe bradycardia." | 3.81 | Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly. ( Cain, N; Kinsman, S; Sechrist, C, 2015) |
| "The present case demonstrates the importance of considering baclofen overdosage in cases of severe coma in combination with an abnormal EEG pattern and sinus bradycardia with normal blood pressure levels, in particular as the substance is popular in internet reports promoting baclofen as a rather harmless "fun drug." | 3.78 | Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature. ( Bangen, U; Bender, K; Eifinger, F; Herkenrath, P; Hoemberg, M; Oberthuer, A; Roth, B; Rothschild, M; Weißhaar, GF, 2012) |
| "We describe two patients in whom serious bradycardia and arterial hypotension occurred after a small intrathecal baclofen (ITB) test bolus." | 3.77 | Cardiovascular alterations heralded by intrathecal baclofen bolus. ( Bramanti, P; D'Aleo, G; D'Aleo, P; Kofler, M; Rifici, C; Saltuari, L, 2011) |
| " After the first admission of 5 mg of oral Baclofen, he collapsed in bed with extreme bradycardia, hypotension, hyperventilation and decreased oxygen saturation." | 3.74 | Heart conduction problems in a tetraplegic patient caused by a single therapeutic dosage of Baclofen. ( Slim, EJ; Smit, CA, 2008) |
| "We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 microg/rat) in awake male Holtzman rats." | 3.73 | The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats. ( Callera, JC; Colombari, E; De Luca, LA; Menani, JV, 2005) |
| "Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system." | 1.33 | Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005) |
| "There was no correlation between the dosage of baclofen and the clinical outcome." | 1.32 | [Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Alamri, A | 1 |
| Mostofi, A | 1 |
| Aziz, T | 1 |
| Pereira, E | 1 |
| Sechrist, C | 1 |
| Kinsman, S | 1 |
| Cain, N | 1 |
| Rifici, C | 1 |
| D'Aleo, G | 1 |
| D'Aleo, P | 1 |
| Bramanti, P | 1 |
| Saltuari, L | 1 |
| Kofler, M | 1 |
| Weißhaar, GF | 1 |
| Hoemberg, M | 1 |
| Bender, K | 1 |
| Bangen, U | 1 |
| Herkenrath, P | 1 |
| Eifinger, F | 1 |
| Rothschild, M | 1 |
| Roth, B | 1 |
| Oberthuer, A | 1 |
| Chodorowski, Z | 2 |
| Sein Anand, J | 2 |
| Wiśniewski, M | 1 |
| Callera, JC | 3 |
| Colombari, E | 1 |
| De Luca, LA | 1 |
| Menani, JV | 1 |
| Burda, P | 1 |
| Smit, CA | 1 |
| Slim, EJ | 1 |
| Bonagamba, LG | 2 |
| Nosjean, A | 2 |
| Laguzzi, R | 2 |
| Machado, BH | 2 |
| Varga, K | 1 |
| Kunos, G | 1 |
| Nugent, S | 1 |
| Katz, MD | 1 |
| Little, TE | 1 |
| Sill, JC | 1 |
| Schumacher, K | 1 |
| Southorn, PA | 1 |
| Reuter, J | 1 |
| Yaksh, TL | 1 |
| Cohen, MB | 1 |
| Gailey, RA | 1 |
| McCoy, GC | 1 |
1 trial available for baclofen and Bradyarrhythmia
| Article | Year |
|---|---|
Bradycardia and hypotension associated with baclofen used during general anesthesia.
Topics: Adult; Aged; Anesthesia, General; Baclofen; Bradycardia; Clinical Trials as Topic; Double-Blind Meth | 1986 |
13 other studies available for baclofen and Bradyarrhythmia
| Article | Year |
|---|---|
Intrathecal baclofen overdose mimicking brainstem death during deep brain stimulation surgery for pain.
Topics: Adult; Baclofen; Bradycardia; Brain Stem; Deep Brain Stimulation; Humans; Infusion Pumps, Implantabl | 2022 |
Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly.
Topics: Baclofen; Bradycardia; Cerebral Palsy; Child; Female; Humans; Hydranencephaly; Injections, Spinal; M | 2015 |
Cardiovascular alterations heralded by intrathecal baclofen bolus.
Topics: Adult; Baclofen; Bradycardia; Electrocardiography; Heart Rate; Humans; Injections, Spinal; Male; Mid | 2011 |
Baclofen intoxication: a "fun drug" causing deep coma and nonconvulsive status epilepticus--a case report and review of the literature.
Topics: Adolescent; Baclofen; Bradycardia; Coma; Drug Overdose; Humans; Male; Muscle Relaxants, Central; Sei | 2012 |
[Acute intoxication with baclofen].
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist | 2004 |
The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats.
Topics: Animals; Baclofen; Blood Pressure; Bradycardia; GABA Agonists; Heart Rate; Hypotension; Male; Muscim | 2005 |
Selected clinical aspects of acute intoxication with baclofen.
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal | 2005 |
Heart conduction problems in a tetraplegic patient caused by a single therapeutic dosage of Baclofen.
Topics: Adult; Baclofen; Bradycardia; Cervical Vertebrae; GABA Agonists; Heart Conduction System; Humans; Ma | 2008 |
Activation of GABAA but not GABAB receptors in the NTSblocked bradycardia of chemoreflex in awake rats.
Topics: Animals; Baclofen; Bradycardia; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; GABA Ag | 1999 |
Activation of GABA receptors in the NTS of awake rats reduces the gain of baroreflex bradycardia.
Topics: Animals; Antihypertensive Agents; Baclofen; Baroreflex; Blood Pressure; Bradycardia; Cardiotonic Age | 2000 |
Inhibition of baroreflex bradycardia by ethanol involves both GABAA and GABAB receptors in the brainstem of the rat.
Topics: 3-Mercaptopropionic Acid; Animals; Baclofen; Bradycardia; Brain Stem; Electric Stimulation; Ethanol; | 1992 |
Baclofen overdose with cardiac conduction abnormalities: case report and review of the literature.
Topics: Adult; Baclofen; Bradycardia; Female; Heart Conduction System; Humans; Myoclonus; Receptors, GABA-A; | 1986 |
Atropine in the treatment of baclofen overdose.
Topics: Adolescent; Atropine; Baclofen; Bradycardia; Humans; Hypotension; Male | 1986 |