Page last updated: 2024-10-23

baclofen and Bipolar Disorder

baclofen has been researched along with Bipolar Disorder in 14 studies

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Baclofen, commonly used to reduce severe muscle spasms in patients with spinal cord injuries, is also active in the brain."3.66A possible neurochemical basis for the neuropsychiatric aspects of baclofen therapy. ( Keegan, DL; Kirby, AR; Richardson, JS, 1983)
"One patient developed withdrawal symptoms after baclofen was stopped, and the other developed a manic attach while receiving the drug."2.37Baclofen-induced psychosis: two cases and a review. ( Iskandar, HL; Yassa, RY, 1988)
"Tardive dystonia is an uncommon, disabling side effect of antipsychotic medication that is generally believed to be resistant to treatment."1.28Tardive dystonia: four case histories. ( Korn, ML; Simpson, GM; Yadalam, KG, 1990)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's6 (42.86)18.2507
2000's2 (14.29)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rivollier, F1
Masson, M1
Shah, R1
Singla, H1
Lee, MS1
Lessell, S1
Kaplan, GB1
McRoberts, RL1
Smokler, HJ1
Keegan, DL1
Richardson, JS1
Kirby, AR1
Wolf, ME1
Almy, G1
Toll, M1
Mosnaim, AD1
Arnold, ES1
Rudd, SM1
Kirshner, H1
Shiah, IS1
Yatham, LN1
Lam, RW1
Tam, EM1
Zis, AP1
Stewart, JT1
Post, RM1
Ketter, TA1
Joffe, RT1
Kramlinger, KL1
Yadalam, KG1
Korn, ML1
Simpson, GM1
Yassa, RY1
Iskandar, HL1

Reviews

1 review available for baclofen and Bipolar Disorder

ArticleYear
Baclofen-induced psychosis: two cases and a review.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:8

    Topics: Acute Disease; Adult; Aged; Baclofen; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Humans; Ma

1988

Trials

2 trials available for baclofen and Bipolar Disorder

ArticleYear
Growth hormone response to baclofen in patients with mania: a pilot study.
    Psychopharmacology, 1999, Volume: 147, Issue:3

    Topics: Acute Disease; Adult; Area Under Curve; Baclofen; Bipolar Disorder; Female; GABA Agonists; GABA-B Re

1999
Lack of beneficial effects of l-baclofen in affective disorder.
    International clinical psychopharmacology, 1991,Winter, Volume: 6, Issue:4

    Topics: Adult; Baclofen; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Hospitalization

1991

Other Studies

11 other studies available for baclofen and Bipolar Disorder

ArticleYear
[Manic symptoms induced by high doses of baclofen: A case report].
    L'Encephale, 2016, Volume: 42, Issue:4

    Topics: Adult; Alcoholism; Antimanic Agents; Baclofen; Bipolar Disorder; Bromazepam; GABA Agonists; Humans;

2016
Baclofen-Related Mania: Lower Threshold for Bipolar Patients?
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:2

    Topics: Alcoholism; Baclofen; Bipolar Disorder; GABA-A Receptor Agonists; Humans; Male; Middle Aged

2017
Lithium-induced periodic alternating nystagmus.
    Neurology, 2003, Jan-28, Volume: 60, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Antimanic Agents; Baclofen; Bipolar Disorder; Female; Fluo

2003
Baclofen as adjunctive treatment for a patient with cocaine dependence and schizoaffective disorder.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: Alcoholism; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Baclofen; Bipolar Disord

2004
A possible neurochemical basis for the neuropsychiatric aspects of baclofen therapy.
    The International journal of neuroscience, 1983, Volume: 20, Issue:3-4

    Topics: Adult; Baclofen; Bipolar Disorder; Brain; Delusions; Depressive Disorder; Dose-Response Relationship

1983
Mania associated with the use of baclofen.
    Biological psychiatry, 1982, Volume: 17, Issue:6

    Topics: Adult; Affective Disorders, Psychotic; Baclofen; Bipolar Disorder; Dyskinesia, Drug-Induced; Humans;

1982
Manic psychosis following rapid withdrawal from baclofen.
    The American journal of psychiatry, 1980, Volume: 137, Issue:11

    Topics: Affective Disorders, Psychotic; Aged; Baclofen; Bipolar Disorder; Dose-Response Relationship, Drug;

1980
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden].
    Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:5 Suppl Ak

    Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Mu

1999
[Current data on bipolar disorders, epilepsy and spasm. 4th Neuro-Forum, Dresden].
    Psychiatrische Praxis, 1999, Volume: 26, Issue:3 Suppl

    Topics: Baclofen; Benzodiazepines; Bipolar Disorder; Clonidine; Epilepsy; Humans; Muscle Relaxants, Central;

1999
A case of mania associated with high-dose baclofen therapy.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:3

    Topics: Aged; Baclofen; Bipolar Disorder; Humans; Male

1992
Tardive dystonia: four case histories.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:1

    Topics: Adult; Antipsychotic Agents; Baclofen; Benzodiazepines; Bipolar Disorder; Dyskinesia, Drug-Induced;

1990