baclofen has been researched along with Binge Alcohol Consumption in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Only few animal models of voluntary binge drinking using an operant paradigm are available in outbred animals and in general they do not display good face validity." | 1.48 | Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking. ( Diouf, M; González-Marín, MC; Jeanblanc, J; Lebourgeois, S; Naassila, M, 2018) |
| "Binge drinking is a form of abusive alcohol drinking defined by the NIAAA as a drinking to blood alcohol levels (BALs)>0." | 1.46 | High Drinking in the Dark (HDID) mice are sensitive to the effects of some clinically relevant drugs to reduce binge-like drinking. ( Barkley-Levenson, A; Crabbe, JC; Hack, WR; Huang, LC; Metten, P; Ozburn, AR; Schlumbohm, JP; Spence, SE, 2017) |
| "Baclofen has been shown to produce enantioselective effects in behavioral assays, including those modeling reflexive and sexual behavior." | 1.42 | Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption. ( Blasingame, SN; Boehm, SL; Kasten, CR, 2015) |
| "Saccharin consumption was not affected." | 1.40 | Intra-nucleus accumbens shell injections of R(+)- and S(-)-baclofen bidirectionally alter binge-like ethanol, but not saccharin, intake in C57Bl/6J mice. ( Boehm, SL; Kasten, CR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crabbe, JC | 1 |
| Ozburn, AR | 1 |
| Metten, P | 1 |
| Barkley-Levenson, A | 1 |
| Schlumbohm, JP | 1 |
| Spence, SE | 1 |
| Hack, WR | 1 |
| Huang, LC | 1 |
| González-Marín, MC | 1 |
| Lebourgeois, S | 1 |
| Jeanblanc, J | 1 |
| Diouf, M | 1 |
| Naassila, M | 1 |
| Kasten, CR | 2 |
| Boehm, SL | 2 |
| Blasingame, SN | 1 |
4 other studies available for baclofen and Binge Alcohol Consumption
| Article | Year |
|---|---|
High Drinking in the Dark (HDID) mice are sensitive to the effects of some clinically relevant drugs to reduce binge-like drinking.
Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Darkness; Disease Models, Animal; Ethanol; Female; M | 2017 |
Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking.
Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Conditioning, Operant; Disease Models, Animal; Dose- | 2018 |
Intra-nucleus accumbens shell injections of R(+)- and S(-)-baclofen bidirectionally alter binge-like ethanol, but not saccharin, intake in C57Bl/6J mice.
Topics: Alcohol Deterrents; Animals; Baclofen; Binge Drinking; Catheters, Indwelling; Central Nervous System | 2014 |
Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption.
Topics: Alcoholism; Animals; Baclofen; Binge Drinking; Disease Models, Animal; Dose-Response Relationship, D | 2015 |