baclofen has been researched along with Autosomal Dominant Hereditary Spastic Paraplegia in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if continuous intrathecal baclofen infusion (CIBI) would provide continuous relief of spasticity in patients with spasticity of cerebral origin, especially children with cerebral palsy." | 3.68 | Continuous intrathecal baclofen infusion for spasticity of cerebral origin. ( Albright, AL; Barron, WB; Fasick, MP; Janosky, J; Polinko, P, 1993) |
| "The main inclusion criteria were: spastic paraparesis with a negative laboratory and imaging work-up (apart from spinal cord atrophy), unsuccessful trial of oral anti-spasticity drugs." | 2.79 | Intrathecal baclofen therapy for the symptomatic treatment of hereditary spastic paraplegia. ( Boutos, N; Boviatsis, E; Dalivigka, Z; Flaskas, T; Gatzonis, S; Korfias, S; Margetis, K; Sakas, D; Siatouni, A; Stranjalis, G; Themistocleous, M, 2014) |
| "We report a case of Spastic paraplegia 8 (SPG8) with a novel mutation of KIAA0196 gene." | 1.48 | A novel KIAA0196 mutation in a Chinese patient with spastic paraplegia 8: A case report. ( Chen, Z; Li, S; Ma, L; Qin, W; Shi, Y; Zhang, J, 2018) |
| "Patients with hereditary spastic paraplegia (HSP), a degenerative central nervous system disorder characterized by progressive lower extremity spasticity, frequently experience symptoms of voiding dysfunction." | 1.29 | Voiding dysfunction in patients with spastic paraplegia: urodynamic evaluation and response to continuous intrathecal baclofen. ( Bushman, W; Meythaler, JM; Steers, WD, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Coulter, IC | 1 |
| Lohkamp, LN | 1 |
| Ibrahim, GM | 1 |
| Ma, L | 1 |
| Shi, Y | 1 |
| Chen, Z | 1 |
| Li, S | 1 |
| Qin, W | 1 |
| Zhang, J | 1 |
| Margetis, K | 1 |
| Korfias, S | 1 |
| Boutos, N | 1 |
| Gatzonis, S | 1 |
| Themistocleous, M | 1 |
| Siatouni, A | 1 |
| Dalivigka, Z | 1 |
| Flaskas, T | 1 |
| Stranjalis, G | 1 |
| Boviatsis, E | 1 |
| Sakas, D | 1 |
| Heetla, HW | 1 |
| Halbertsma, JP | 1 |
| Dekker, R | 1 |
| Staal, MJ | 1 |
| van Laar, T | 1 |
| Klebe, S | 1 |
| Stolze, H | 1 |
| Kopper, F | 1 |
| Lorenz, D | 1 |
| Wenzelburger, R | 1 |
| Deuschl, G | 1 |
| Volkmann, J | 1 |
| Contino, G | 1 |
| Novelli, G | 1 |
| Bushman, W | 1 |
| Steers, WD | 2 |
| Meythaler, JM | 2 |
| Broggi, G | 2 |
| Servello, D | 2 |
| Brock, S | 1 |
| Dones, I | 2 |
| Albright, AL | 1 |
| Barron, WB | 1 |
| Fasick, MP | 1 |
| Polinko, P | 1 |
| Janosky, J | 1 |
| Molteni, F | 1 |
| Mariani, G | 1 |
| Detrembleur, C | 1 |
| Lejeune, TM | 1 |
| Plaghki, L | 1 |
| Dan, B | 1 |
| Cheron, G | 1 |
| Saltuari, L | 1 |
| Kronenberg, M | 1 |
| Marosi, MJ | 1 |
| Kofler, M | 1 |
| Russegger, L | 1 |
| Rifici, C | 1 |
| Bramanti, P | 1 |
| Gerstenbrand, F | 1 |
| Tuel, SM | 1 |
| Cross, LL | 1 |
| Sesco, DC | 1 |
| Haworth, CS | 1 |
| Vanneste, J | 1 |
| Augustijn, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility[NCT03250988] | 60 participants (Actual) | Observational | 2018-01-30 | Completed | |||
| A Randomized, Placebo Controlled Trial of Botulinum Toxin for Paratonic Rigidity in People With Advanced Cognitive Impairment[NCT02212119] | Phase 2 | 10 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| Study of the Efficacy of the Selective Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic Patient Following the ICF Model. A Prospective, Randomized, Controlled Single Blind Study[NCT00825097] | Phase 3 | 16 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for baclofen and Autosomal Dominant Hereditary Spastic Paraplegia
| Article | Year |
|---|---|
Hereditary spastic paraplegia: clinical genomics and pharmacogenetic perspectives.
Topics: Baclofen; GABA Agonists; Genetic Linkage; Humans; Pharmacogenetics; Spastic Paraplegia, Hereditary | 2006 |
5 trials available for baclofen and Autosomal Dominant Hereditary Spastic Paraplegia
| Article | Year |
|---|---|
Intrathecal baclofen therapy for the symptomatic treatment of hereditary spastic paraplegia.
Topics: Adult; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; | 2014 |
Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia.
Topics: Baclofen; Biomechanical Phenomena; GABA Agonists; Gait; Humans; Injections, Spinal; Spastic Parapleg | 2005 |
The treatment of spasticity by intrathecal administration of baclofen: a preliminary personal experience.
Topics: Adult; Baclofen; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Male; Middle Aged; | 1993 |
Long-term intrathecal baclofen treatment in supraspinal spasticity.
Topics: Adult; Baclofen; Brain Injuries; Cerebral Palsy; Humans; Infusion Pumps; Injections, Spinal; Male; M | 1992 |
Intrathecal baclofen in hereditary spastic paraparesis.
Topics: Baclofen; Double-Blind Method; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Injection | 1992 |
9 other studies available for baclofen and Autosomal Dominant Hereditary Spastic Paraplegia
| Article | Year |
|---|---|
Intrathecal baclofen for hereditary spastic paraplegia (HSP).
Topics: Baclofen; Humans; Injections, Spinal; Spastic Paraplegia, Hereditary | 2020 |
A novel KIAA0196 mutation in a Chinese patient with spastic paraplegia 8: A case report.
Topics: Asian People; Baclofen; Child; Electromyography; Humans; Male; Muscle Relaxants, Central; Neural Con | 2018 |
Improved gait performance in a patient with hereditary spastic paraplegia after a continuous intrathecal baclofen test infusion and subsequent pump implantation: a case report.
Topics: Baclofen; Electromyography; GABA-B Receptor Agonists; Gait Disorders, Neurologic; Humans; Infusion P | 2015 |
Voiding dysfunction in patients with spastic paraplegia: urodynamic evaluation and response to continuous intrathecal baclofen.
Topics: Adult; Baclofen; Humans; Injections, Spinal; Male; Middle Aged; Spastic Paraplegia, Hereditary; Urin | 1993 |
Continuous intrathecal baclofen infusion for spasticity of cerebral origin.
Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Humans; Infusion Pumps, Implan | 1993 |
A neurophysiological method for the evaluation of motor performance in spastic walking patients.
Topics: Adult; Baclofen; Electromyography; Female; Humans; Isometric Contraction; Male; Middle Aged; Motor S | 1995 |
[Objective measures of muscle stiffness in the ankle. Evaluation of the effect of intrathecal injection of baclofen in spastic patients].
Topics: Adult; Ankle; Baclofen; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Spastic Paraple | 1998 |
Intrathecal baclofen normalizes motor strategy for squatting in familial spastic paraplegia: a case study.
Topics: Adult; Baclofen; Humans; Injections, Spinal; Male; Movement; Muscle Relaxants, Central; Spastic Para | 2000 |
Intrathecal baclofen for treatment of spasticity.
Topics: Adult; Aged; Baclofen; Dose-Response Relationship, Drug; Humans; Injections, Spinal; Male; Paraplegi | 1990 |