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baclofen and Autonomic Dysreflexia

baclofen has been researched along with Autonomic Dysreflexia in 8 studies

Autonomic Dysreflexia: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)

Research Excerpts

ExcerptRelevanceReference
"To study the relationship between autonomic dysreflexia and intrathecal baclofen in patients with spinal cord injury."7.88An investigation of the relationship between autonomic dysreflexia and intrathecal baclofen in patients with spinal cord injury. ( Del Fabro, AS; Mejia, M; Nemunaitis, G, 2018)
"Baclofen withdrawal syndrome is a rare and potentially life-threatening condition manifesting with autonomic dysreflexia, high fevers, spasticity, seizures, and multiorgan failure."7.76Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome. ( Kireyev, D; Poh, KK, 2010)
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."7.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)
"To report insidious development of autonomic dysreflexia and hydronephrosis due to dyssynergic voiding following discontinuation of intrathecal baclofen therapy."7.72Delayed complications of discontinuation of intrathecal baclofen therapy: resurgence of dyssynergic voiding, which triggered off autonomic dysreflexia and hydronephrosis. ( Hughes, PL; Mansour, P; Oo, T; Singh, G; Soni, BM; Vaidyanathan, S, 2004)
"To study the relationship between autonomic dysreflexia and intrathecal baclofen in patients with spinal cord injury."3.88An investigation of the relationship between autonomic dysreflexia and intrathecal baclofen in patients with spinal cord injury. ( Del Fabro, AS; Mejia, M; Nemunaitis, G, 2018)
"Baclofen withdrawal syndrome is a rare and potentially life-threatening condition manifesting with autonomic dysreflexia, high fevers, spasticity, seizures, and multiorgan failure."3.76Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome. ( Kireyev, D; Poh, KK, 2010)
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."3.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)
"To report insidious development of autonomic dysreflexia and hydronephrosis due to dyssynergic voiding following discontinuation of intrathecal baclofen therapy."3.72Delayed complications of discontinuation of intrathecal baclofen therapy: resurgence of dyssynergic voiding, which triggered off autonomic dysreflexia and hydronephrosis. ( Hughes, PL; Mansour, P; Oo, T; Singh, G; Soni, BM; Vaidyanathan, S, 2004)
"Baclofen per se has the potential of lowering blood pressure."1.35Intrathecal baclofen for autonomic instability due to spinal cord injury. ( Kofler, M; Poustka, K; Saltuari, L, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Delhaas, EM1
Frankema, SPG1
Huygen, FJPM1
Del Fabro, AS1
Mejia, M1
Nemunaitis, G1
Kofler, M1
Poustka, K1
Saltuari, L1
Salazar, ML1
Eiland, LS1
Kireyev, D1
Poh, KK1
Vaidyanathan, S1
Soni, BM1
Oo, T1
Hughes, PL1
Singh, G1
Mansour, P1
Becker, R1
Benes, L1
Sure, U1
Hellwig, D1
Bertalanffy, H1
Coffey, RJ1
Edgar, TS1
Francisco, GE1
Graziani, V1
Meythaler, JM1
Ridgely, PM1
Sadiq, SA1
Turner, MS1

Reviews

1 review available for baclofen and Autonomic Dysreflexia

ArticleYear
Abrupt withdrawal from intrathecal baclofen: recognition and management of a potentially life-threatening syndrome.
    Archives of physical medicine and rehabilitation, 2002, Volume: 83, Issue:6

    Topics: Anti-Anxiety Agents; Autonomic Dysreflexia; Baclofen; Benzodiazepines; Diagnosis, Differential; GABA

2002

Other Studies

7 other studies available for baclofen and Autonomic Dysreflexia

ArticleYear
Intrathecal baclofen as emergency treatment alleviates severe intractable autonomic dysreflexia in cervical spinal cord injury.
    The journal of spinal cord medicine, 2021, Volume: 44, Issue:4

    Topics: Autonomic Dysreflexia; Baclofen; Cervical Cord; Emergency Treatment; Humans; Infusion Pumps, Implant

2021
An investigation of the relationship between autonomic dysreflexia and intrathecal baclofen in patients with spinal cord injury.
    The journal of spinal cord medicine, 2018, Volume: 41, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Autonomic Dysreflexia; Baclofen; Female; Humans; Infusions, Spinal;

2018
Intrathecal baclofen for autonomic instability due to spinal cord injury.
    Autonomic neuroscience : basic & clinical, 2009, Mar-12, Volume: 146, Issue:1-2

    Topics: Abdominal Wall; Antihypertensive Agents; Autonomic Dysreflexia; Baclofen; Benzimidazoles; Biphenyl C

2009
Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy.
    Pediatric emergency care, 2008, Volume: 24, Issue:10

    Topics: Abdominal Pain; Adolescent; Autonomic Dysreflexia; Baclofen; Cerebral Palsy; Diagnosis, Differential

2008
Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome.
    The American heart hospital journal, 2010,Summer, Volume: 8, Issue:1

    Topics: Adult; Autonomic Dysreflexia; Baclofen; Bundle-Branch Block; Electrocardiography; Fever; GABA-B Rece

2010
Delayed complications of discontinuation of intrathecal baclofen therapy: resurgence of dyssynergic voiding, which triggered off autonomic dysreflexia and hydronephrosis.
    Spinal cord, 2004, Volume: 42, Issue:10

    Topics: Adolescent; Autonomic Dysreflexia; Baclofen; Humans; Hydronephrosis; Injections, Spinal; Male; Parap

2004
Intrathecal baclofen alleviates autonomic dysfunction in severe brain injury.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:4

    Topics: Adult; Animals; Autonomic Dysreflexia; Autonomic Nervous System; Baclofen; Brain; Brain Injuries; Hu

2000