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baclofen and Anochlesia

baclofen has been researched along with Anochlesia in 14 studies

Research Excerpts

ExcerptRelevanceReference
"A role for gamma-aminobutyric acid (GABA) in the pathophysiology of schizophrenia was first suggested by Eugene Roberts in 1972."4.76The interaction between GABA and dopamine: implications for schizophrenia. ( Garbutt, JC; van Kammen, DP, 1983)
" Ketamine, PCP, and MK-801 enhanced catalepsy along inverted U-shaped dose-response curves likely because higher doses affected motor coordination, which limited their catalepsy-enhancing effects."1.35Cataleptic effects of gamma-hydroxybutyrate (GHB) and baclofen in mice: mediation by GABA(B) receptors, but differential enhancement by N-methyl-d-aspartate (NMDA) receptor antagonists. ( France, CP; Koek, W, 2008)
" At 100 mg/kg, CGP35348 shifted the dose-response curves of baclofen and SKF97541 to the right but not those of GHB and GBL; at 320 mg/kg, CGP35348 shifted the curves of all four compounds to the right."1.34Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348. ( Coop, A; Koek, W; Mercer, SL, 2007)
"0 mg/kg induced a significant leftward displacement of the control dose-response curve constructed for apomorphine (0."1.29Effect of manipulation of the GABA system on dopamine-related behaviors. ( Palermo-Neto, J; Sandoval, MR, 1995)
"Baclofen-induced catalepsy was accompanied by tonic activity in the electromyogram (EMG) recorded from the gastrocnemius muscle, which is considered to be a measure of limb rigidity."1.27Behavioral actions of baclofen in the rat ventromedial thalamic nucleus: antagonism by delta-aminovalerate. ( Klockgether, T; Schwarz, M; Sontag, KH; Wüllner, U, 1987)
"Haloperidol-induced catalepsy in rats is reduced by low dose baclofen and is potentiated by high dose baclofen."1.26Biphasic dose-response effect of baclofen on haloperidol catalepsy in the rat. ( Richardson, AK; Richardson, JS, 1982)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koek, W2
Mercer, SL1
Coop, A1
France, CP1
Garbutt, JC1
van Kammen, DP1
Balsara, JJ1
Muley, MP1
Vaidya, AS1
Chandorkar, AG1
Richardson, JS1
Richardson, AK1
Capasso, A1
Di Giannuario, A1
Loizzo, A1
Pieretti, S1
Sorrentino, L1
Sandoval, MR1
Palermo-Neto, J1
Davies, JA1
Williams, J1
Kääriäinen, I2
Kääriäinen, K1
Vikberg, P1
Mehta, AK1
Ticku, MK1
Pertwee, RG1
Greentree, SG1
Swift, PA1
Wüllner, U1
Klockgether, T1
Schwarz, M1
Sontag, KH1

Reviews

1 review available for baclofen and Anochlesia

ArticleYear
The interaction between GABA and dopamine: implications for schizophrenia.
    Schizophrenia bulletin, 1983, Volume: 9, Issue:3

    Topics: Animals; Antipsychotic Agents; Baclofen; Brain Chemistry; Catalepsy; Dopamine; gamma-Aminobutyric Ac

1983

Other Studies

13 other studies available for baclofen and Anochlesia

ArticleYear
Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.
    Psychopharmacology, 2007, Volume: 192, Issue:3

    Topics: 4-Butyrolactone; Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; GABA Agonists; GABA

2007
Cataleptic effects of gamma-hydroxybutyrate (GHB) and baclofen in mice: mediation by GABA(B) receptors, but differential enhancement by N-methyl-d-aspartate (NMDA) receptor antagonists.
    Psychopharmacology, 2008, Volume: 199, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Area Under Curve; Ataxia; Baclofen; Catalepsy; Data Interpretatio

2008
Effects of baclofen on dopamine-dependent behaviors in mice.
    Psychopharmacology, 1981, Volume: 75, Issue:4

    Topics: Animals; Baclofen; Behavior, Animal; Catalepsy; Dopamine; Dose-Response Relationship, Drug; Humans;

1981
Biphasic dose-response effect of baclofen on haloperidol catalepsy in the rat.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4

    Topics: Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Rats; Rat

1982
Dexamethasone reduces the behavioural effects induced by baclofen in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:5

    Topics: Animals; Baclofen; Behavior, Animal; Catalepsy; Dexamethasone; Dose-Response Relationship, Drug; Mal

1995
Effect of manipulation of the GABA system on dopamine-related behaviors.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1995, Volume: 28, Issue:1

    Topics: 3-Mercaptopropionic Acid; Animals; Apomorphine; Baclofen; Catalepsy; Dopamine Agonists; GABA Agents;

1995
The effect of baclofen on alpha-flupenthixol-induced catalepsy in the rat.
    British journal of pharmacology, 1978, Volume: 62, Issue:2

    Topics: Aminobutyrates; Animals; Baclofen; Catalepsy; Drug Interactions; Female; Flupenthixol; Humans; Rats;

1978
Effects of GABAergic drugs on the catalepsy, striatal homovanillic acid increase and antinociception caused by pilocarpine in rats.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Brain; Catalepsy; Corpus Striatum;

1977
Effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:3

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Brain Chemistry; Catalepsy; Corpus

1976
Effects of aminooxyacetic acid and baclofen on catalepsy, striatal homovanillic acid increase and antinociception caused by methadone in rats.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:5

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Catalepsy; Corpus Stria

1976
Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.
    Life sciences, 1990, Volume: 46, Issue:1

    Topics: Animals; Aspartic Acid; Baclofen; Bromocriptine; Catalepsy; Dibenzocycloheptenes; Dizocilpine Maleat

1990
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
    Neuropharmacology, 1988, Volume: 27, Issue:12

    Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazen

1988
Behavioral actions of baclofen in the rat ventromedial thalamic nucleus: antagonism by delta-aminovalerate.
    Brain research, 1987, Sep-29, Volume: 422, Issue:1

    Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Bicuculline; Catalepsy; Dose-Response Relation

1987