baclofen has been researched along with Amnesia in 8 studies
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a patient in whom long-term, therapeutic infusion of the selective gamma-amino-butyric acid type B (GABAB) receptor agonist, baclofen, into the cerebrospinal fluid (CSF) gave rise to three distinct varieties of memory impairment: i) repeated, short periods of severe global amnesia, ii) accelerated long-term forgetting (ALF), evident over intervals of days and iii) a loss of established autobiographical memories." | 7.83 | The GABAB receptor agonist, baclofen, contributes to three distinct varieties of amnesia in the human brain - A detailed case report. ( Carr, M; Dewar, M; Hoefeijzers, S; Milton, F; Streatfield, C; Zeman, A, 2016) |
| "We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia." | 7.71 | Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001) |
| "The role of cholinergic and GABAergic neuronal systems on the cycloheximide (CXM)-induced amnesia was investigated using the step-down-type passive avoidance task in mice." | 7.67 | Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice. ( Itoh, K; Kameyama, T; Nabeshima, T; Noda, Y, 1988) |
| "We describe a patient in whom long-term, therapeutic infusion of the selective gamma-amino-butyric acid type B (GABAB) receptor agonist, baclofen, into the cerebrospinal fluid (CSF) gave rise to three distinct varieties of memory impairment: i) repeated, short periods of severe global amnesia, ii) accelerated long-term forgetting (ALF), evident over intervals of days and iii) a loss of established autobiographical memories." | 3.83 | The GABAB receptor agonist, baclofen, contributes to three distinct varieties of amnesia in the human brain - A detailed case report. ( Carr, M; Dewar, M; Hoefeijzers, S; Milton, F; Streatfield, C; Zeman, A, 2016) |
| "GABA analogs containing phenyl (phenibut) or para-chlorophenyl (baclofen) substituents demonstrated nootropic activity in a dose of 20 mg/kg: they improved passive avoidance conditioning, decelerated its natural extinction, and exerted antiamnestic effect on the models of amnesia provoked by scopolamine or electroshock." | 3.83 | Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid. ( Bagmetova, VV; Berestovitskaya, VM; Borodkina, LE; Tyurenkov, IN; Vasil'eva, OS, 2016) |
| "We investigated the effects of baclofen, a selective GABA-B receptor agonist, on certain behaviours in rats after short-term hypoxia, as a model of experimentally induced amnesia." | 3.71 | Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. ( Car, H; Nadlewska, A; Oksztel, R; Wiśniewski, K, 2001) |
| " Cetyl GABA, sodium and lithium hydroxybutyrates and phenibut were shown to be able to decrease the retrograde amnesia caused by electroshock in passive avoidance performance." | 3.67 | [Nootropic properties of gamma-aminobutyric acid derivatives]. ( Ostrovskaia, RU; Trofimov, SS, 1984) |
| "The role of cholinergic and GABAergic neuronal systems on the cycloheximide (CXM)-induced amnesia was investigated using the step-down-type passive avoidance task in mice." | 3.67 | Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice. ( Itoh, K; Kameyama, T; Nabeshima, T; Noda, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeman, A | 1 |
| Hoefeijzers, S | 1 |
| Milton, F | 1 |
| Dewar, M | 1 |
| Carr, M | 1 |
| Streatfield, C | 1 |
| Tyurenkov, IN | 1 |
| Borodkina, LE | 1 |
| Bagmetova, VV | 1 |
| Berestovitskaya, VM | 1 |
| Vasil'eva, OS | 1 |
| Farahmandfar, M | 1 |
| Akbarabadi, A | 1 |
| Bakhtazad, A | 1 |
| Zarrindast, MR | 1 |
| Ostrovskaia, RU | 1 |
| Trofimov, SS | 1 |
| Galeotti, N | 2 |
| Ghelardini, C | 2 |
| Bartolini, A | 2 |
| Manetti, D | 1 |
| Bellucci, C | 1 |
| Dei, S | 1 |
| Gualtieri, F | 1 |
| Romanelli, MN | 1 |
| Scapecchi, S | 1 |
| Teodori, E | 1 |
| Car, H | 1 |
| Oksztel, R | 1 |
| Nadlewska, A | 1 |
| Wiśniewski, K | 1 |
| Nabeshima, T | 1 |
| Noda, Y | 1 |
| Itoh, K | 1 |
| Kameyama, T | 1 |
8 other studies available for baclofen and Amnesia
| Article | Year |
|---|---|
The GABAB receptor agonist, baclofen, contributes to three distinct varieties of amnesia in the human brain - A detailed case report.
Topics: Amnesia; Analgesics; Baclofen; Female; Humans; Memory, Episodic; Memory, Short-Term; Middle Aged; Pa | 2016 |
Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Baclofen; Cinnamates; Coma; Electroshock; gam | 2016 |
Recovery from ketamine-induced amnesia by blockade of GABA-A receptor in the medial prefrontal cortex of mice.
Topics: Amnesia; Animals; Baclofen; Bicuculline; Catheters, Indwelling; Dose-Response Relationship, Drug; Ex | 2017 |
[Nootropic properties of gamma-aminobutyric acid derivatives].
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classi | 1984 |
Effect of pertussis toxin on baclofen- and diphenhydramine-induced amnesia.
Topics: Amnesia; Animals; Baclofen; Diphenhydramine; GABA Agonists; GTP-Binding Proteins; Histamine H1 Antag | 1998 |
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response | 2000 |
Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats.
Topics: Amnesia; Animals; Anxiety; Avoidance Learning; Baclofen; Disease Models, Animal; Exploratory Behavio | 2001 |
Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice.
Topics: Amnesia; Animals; Avoidance Learning; Baclofen; Bicuculline; Butylscopolammonium Bromide; Cyclohexim | 1988 |