baclofen has been researched along with Alzheimer Disease in 7 studies
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of baclofen, a structural analog of gamma-aminobutyric acid (GABA), is described in the treatment of a patient with tardive dystonia." | 7.67 | Baclofen treatment in a patient with tardive dystonia. ( Allen, A; Lux, WE; Rosse, RB, 1986) |
| "The use of baclofen, a structural analog of gamma-aminobutyric acid (GABA), is described in the treatment of a patient with tardive dystonia." | 3.67 | Baclofen treatment in a patient with tardive dystonia. ( Allen, A; Lux, WE; Rosse, RB, 1986) |
| "They have been of value in treating pain of cancer and spasticity through spinal subarachnoid catheters." | 2.37 | Drug pumps for treatment of neurologic diseases and pain. ( Penn, RD, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilipenko, V | 1 |
| Narbute, K | 1 |
| Beitnere, U | 1 |
| Rumaks, J | 1 |
| Pupure, J | 1 |
| Jansone, B | 1 |
| Klusa, V | 1 |
| Chumakov, I | 1 |
| Nabirotchkin, S | 1 |
| Cholet, N | 1 |
| Milet, A | 1 |
| Boucard, A | 1 |
| Toulorge, D | 1 |
| Pereira, Y | 1 |
| Graudens, E | 1 |
| Traoré, S | 1 |
| Foucquier, J | 1 |
| Guedj, M | 1 |
| Vial, E | 1 |
| Callizot, N | 1 |
| Steinschneider, R | 1 |
| Maurice, T | 1 |
| Bertrand, V | 1 |
| Scart-Grès, C | 1 |
| Hajj, R | 1 |
| Cohen, D | 1 |
| Wang, SJ | 1 |
| Huang, CC | 1 |
| Gean, PW | 1 |
| Crystal, HA | 1 |
| Chu, DC | 1 |
| Penney, JB | 1 |
| Young, AB | 1 |
| Penn, RD | 1 |
| Rosse, RB | 1 |
| Allen, A | 1 |
| Lux, WE | 1 |
1 review available for baclofen and Alzheimer Disease
| Article | Year |
|---|---|
Drug pumps for treatment of neurologic diseases and pain.
Topics: Alzheimer Disease; Baclofen; Bethanechol; Bethanechol Compounds; Catheters, Indwelling; Chronic Dise | 1985 |
6 other studies available for baclofen and Alzheimer Disease
| Article | Year |
|---|---|
Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Baclofen; Brain; Cognition; Disease Models, Animal; Dose-Response Relati | 2018 |
Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy.
Topics: Acamprosate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apop | 2015 |
Investigations on the mechanism of tetrahydro-9-aminoacridine-induced presynaptic inhibition in the rat amygdala.
Topics: 4-Aminopyridine; Alzheimer Disease; Amygdala; Animals; Baclofen; Dose-Response Relationship, Drug; M | 1996 |
Baclofen therapy may be associated with chorea in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Baclofen; Chorea; Humans; Male | 1990 |
Cortical GABAB and GABAA receptors in Alzheimer's disease: a quantitative autoradiographic study.
Topics: Aged; Alzheimer Disease; Animals; Autoradiography; Baclofen; Binding, Competitive; Frontal Lobe; Hum | 1987 |
Baclofen treatment in a patient with tardive dystonia.
Topics: Aged; Alzheimer Disease; Baclofen; Dystonia; Female; Haloperidol; Humans | 1986 |