baclofen has been researched along with Alcoholic Cirrhosis in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The usual side effects such as drowsiness were frequent (22%) but no serious adverse events (AEs) or overt encephalopathy related to baclofen was reported." | 1.91 | Baclofen Combined With Psychosocial Care is Useful and Safe in Alcohol-Related Cirrhosis Patients: A Real-Life Multicenter Study. ( Alqallaf, S; Barrault, C; Behar, V; Bourcier, V; Cadranel, JF; Costentin, C; Hagege, H; Jung, C; Labarriere, D; Lamote-Chaouche, I; Laugier, J; Le Gruyer, A; Lison, H; Ripault, MP; Thevenot, T, 2023) |
| " At a mean dosage of 40 mg/day (extremes: 30-210), the median daily alcohol consumption reduced from 80 to 0 g/day (P<0." | 1.46 | One year of baclofen in 100 patients with or without cirrhosis: a French real-life experience. ( Barrault, C; Béhar, V; Cadranel, JF; Costentin, C; Garioud, A; Hagège, H; Lison, H; Medmoun, M; Pulwermacher, G; Roudot-Thoraval, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrault, C | 3 |
| Alqallaf, S | 2 |
| Lison, H | 3 |
| Lamote-Chaouche, I | 2 |
| Bourcier, V | 2 |
| Laugier, J | 2 |
| Thevenot, T | 2 |
| Labarriere, D | 2 |
| Ripault, MP | 2 |
| Le Gruyer, A | 2 |
| Costentin, C | 3 |
| Behar, V | 3 |
| Hagege, H | 3 |
| Jung, C | 2 |
| Cadranel, JF | 3 |
| Roudot-Thoraval, F | 1 |
| Garioud, A | 1 |
| Medmoun, M | 1 |
| Pulwermacher, G | 1 |
| Ameisen, O | 1 |
| Leggio, L | 1 |
| Ferrulli, A | 1 |
| Zambon, A | 1 |
| Caputo, F | 1 |
| Kenna, GA | 1 |
| Swift, RM | 1 |
| Addolorato, G | 1 |
| Garbutt, JC | 1 |
| Flannery, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind, Placebo-Controlled, Randomized Human Laboratory Pilot Study of Baclofen in Anxious Alcoholics[NCT01751386] | Phase 2 | 39 participants (Actual) | Interventional | 2012-12-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Amount of alcohol was measured as the number of mini-drinks each participant decided to drink (0-8 mini-drinks). The alcohol content of each mini-drink was calculated based on the participants' total body water, and was designed to raise the blood alcohol concentration by 0.015 g/dL. (NCT01751386)
Timeframe: 2 hours
| Intervention | mini-drinks (Mean) |
|---|---|
| Baclofen | 4.11 |
| Placebo | 4.5 |
2 trials available for baclofen and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection.
Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Baclofen; Female; GABA-B Receptor Agonists; | 2012 |
Baclofen for alcoholism.
Topics: Alcoholism; Baclofen; GABA Agonists; Humans; Liver Cirrhosis, Alcoholic; Patient Selection; Temperan | 2007 |
3 other studies available for baclofen and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Baclofen Combined With Psychosocial Care is Useful and Safe in Alcohol-Related Cirrhosis Patients: A Real-Life Multicenter Study.
Topics: Alcohol Drinking; Alcoholism; Baclofen; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Psychia | 2023 |
Baclofen Combined With Psychosocial Care is Useful and Safe in Alcohol-Related Cirrhosis Patients: A Real-Life Multicenter Study.
Topics: Alcohol Drinking; Alcoholism; Baclofen; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Psychia | 2023 |
Baclofen Combined With Psychosocial Care is Useful and Safe in Alcohol-Related Cirrhosis Patients: A Real-Life Multicenter Study.
Topics: Alcohol Drinking; Alcoholism; Baclofen; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Psychia | 2023 |
Baclofen Combined With Psychosocial Care is Useful and Safe in Alcohol-Related Cirrhosis Patients: A Real-Life Multicenter Study.
Topics: Alcohol Drinking; Alcoholism; Baclofen; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Psychia | 2023 |
One year of baclofen in 100 patients with or without cirrhosis: a French real-life experience.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Baclofen; Female; France; GABA-B Receptor A | 2017 |
Treatment of alcohol-use disorders.
Topics: Alcohol-Related Disorders; Animals; Baclofen; Drug Approval; Drug Evaluation, Preclinical; Humans; L | 2009 |