baclofen has been researched along with Akinetic-Rigid Variant of Huntington Disease in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QA) is an endogenous excitotoxin present in mammalian brain that reproduces many of the histologic and neurochemical features of Huntington's disease (HD)." | 1.27 | Systemic approaches to modifying quinolinic acid striatal lesions in rats. ( Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ, 1988) |
| "A 29-year-old woman with known Huntington's disease took from 900 to 970 mg of Lioresal, a cogener of gamma amino butyric acid (GABA) used experimentally to treat muscle spasm." | 1.26 | Overdose of lioresal. ( Paulson, GW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, W | 1 |
| Seo, H | 1 |
| Roccatagliata, G | 2 |
| Albano, C | 2 |
| Marsden, CD | 1 |
| Sheehy, MP | 1 |
| Fisher, RH | 1 |
| Norris, JW | 1 |
| DeManuele, F | 1 |
| Ridgley, B | 1 |
| Malyon, C | 1 |
| Rubin, AJ | 1 |
| King, WM | 1 |
| Reinbold, KA | 1 |
| Shoulson, I | 2 |
| Paulson, GW | 2 |
| Besio, G | 1 |
| Ivaldi, EM | 1 |
| Beal, MF | 1 |
| Kowall, NW | 1 |
| Swartz, KJ | 1 |
| Ferrante, RJ | 1 |
| Martin, JB | 1 |
| Odoroff, C | 1 |
| Oakes, D | 1 |
| Behr, J | 1 |
| Goldblatt, D | 1 |
| Caine, E | 1 |
| Kennedy, J | 1 |
| Miller, C | 1 |
| Bamford, K | 1 |
| Rubin, A | 1 |
3 trials available for baclofen and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
GABA and movement disorders.
Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; | 1981 |
Quantitative longitudinal assessment of saccades in Huntington's disease.
Topics: Adult; Aged; Baclofen; Biomarkers; Eye Movements; Humans; Huntington Disease; Longitudinal Studies; | 1993 |
A controlled clinical trial of baclofen as protective therapy in early Huntington's disease.
Topics: Adolescent; Adult; Baclofen; Clinical Trials as Topic; Female; Humans; Huntington Disease; Male; Mid | 1989 |
7 other studies available for baclofen and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington's disease model mice.
Topics: Animals; Baclofen; Cell Survival; Corpus Striatum; Disease Models, Animal; GABA-B Receptor Agonists; | 2014 |
[Therapy of Huntington's chorea: a pharmacological and clinical approach to the organization of the basal ganglia].
Topics: Adult; Aged; Baclofen; Basal Ganglia; Behavior; Biperiden; Bromocriptine; Female; Fluphenazine; Homo | 1980 |
Huntington's chorea.
Topics: Baclofen; Canada; gamma-Aminobutyric Acid; Health Facilities; Humans; Huntington Disease; Hydroxybut | 1982 |
Lioresal in Huntington's disease.
Topics: Aminobutyrates; Baclofen; Dantrolene; Diazepam; Drug Evaluation; Gait; gamma-Aminobutyric Acid; Grow | 1976 |
Overdose of lioresal.
Topics: Adult; Aminobutyrates; Baclofen; Female; Humans; Huntington Disease; Suicide, Attempted | 1976 |
[Choreic dyskinesia and GABA - pharmaco-clinical approach. Preliminary note].
Topics: Adult; Aminobutyrates; Baclofen; Extrapyramidal Tracts; Female; Homovanillic Acid; Humans; Huntingto | 1978 |
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Stria | 1988 |