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baclofen and Aging

baclofen has been researched along with Aging in 38 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

Excerpt	Relevance	Reference
"Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy."	7.76	Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"Baclofen is a selective gamma-aminobutyric acid (GABA) type B agonist that may have important medicinal uses, such as in analgesics and drug addiction treatment."	5.37	Differential effects of aging on EEG after baclofen administration. ( Cui, J; Fu, Y; Ma, Y, 2011)
"Intrathecal baclofen is an effective treatment for spasticity in patients with cerebral palsy."	3.76	Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"A well known drug in the treatment of spasticity is the GABA(B) agonist Baclofen."	1.31	Baclofen inhibits ANP-mediated cyclic GMP synthesis in the rat cervical spinal cord. ( de Louw, AJ; de Vente, J; Steinbusch, HP; Steinbusch, HW; Troost, J; Vles, JS, 2002)

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (10.53)	18.7374
1990's	19 (50.00)	18.2507
2000's	9 (23.68)	29.6817
2010's	6 (15.79)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Beas, BS	1
McQuail, JA	2
Ban Uelos, C	1
Setlow, B	1
Bizon, JL	1
Burn, SC	1
Zeller, R	1
Drake, JM	1
Fu, Y	1
Cui, J	1
Ma, Y	1
Luo, B	1
Wang, HT	1
Su, YY	1
Wu, SH	1
Chen, L	1
Borthwick, L	1
Davis, KN	1
Miller, F	1
Hampson, RE	1
Deadwyler, SA	1
Howlett, AC	1
Nicolle, MM	1
Rónai, AZ	1
Kató, E	1
Al-Khrasani, M	1
Hajdú, M	1
Müllner, K	1
Elor, G	1
Gyires, K	1
Fürst, S	1
Palkovits, M	1
Stöhr, J	2
Bourova, L	1
Hejnova, L	1
Ihnatovych, I	1
Novotny, J	2
Svoboda, P	2
Diaz, SL	1
Barros, VG	1
Antonelli, MC	1
Rubio, MC	1
Balerio, GN	1
Bay, KD	1
Beck, P	1
Skinner, RD	1
Garcia-Rill, E	1
Maggi, CA	1
Santicioli, P	1
Meli, A	1
Acs, Z	1
Makara, GB	1
Stark, E	1
Ishige, K	1
Beales, PE	1
Hawa, M	1
Williams, AJ	1
Albertini, MC	1
Giorgini, A	1
Pozzilli, P	1
Tremblay, E	1
Ben-Ari, Y	2
Roisin, MP	1
Strata, F	1
Cherubini, E	1
Rey-Roldan, EB	1
Lux-Lantos, AR	1
Gonzalez-Iglesias, AE	1
Becu-Villalobos, D	1
Libertun, C	1
Ichida, T	1
Kuriyama, K	1
Caillard, O	1
McLean, HA	1
Gaïarsa, JL	1
Lo, YJ	1
Rao, SC	1
Sanes, DH	2
Kotak, VC	1
Korada, S	1
Schwartz, IR	1
Zhang, W	1
Elsen, F	1
Barnbrock, A	1
Richter, DW	1
Straus, C	1
Wilson, RJ	1
Remmers, JE	1
Him, A	1
Johnston, AR	1
Yau, JL	1
Seckl, J	1
Dutia, MB	1
Sickmann, T	1
Alzheimer, C	1
de Louw, AJ	1
de Vente, J	1
Steinbusch, HP	1
Steinbusch, HW	1
Troost, J	1
Vles, JS	1
Goldblatt, D	1
Moguilevsky, JA	1
Carbone, S	1
Szwarcfarb, B	1
Lovinger, DM	1
Harrison, NL	1
Lambert, NA	1
Moshé, SL	1
Sperber, EF	1
Brown, LL	1
Tempel, A	1
Erdö, SL	1
Meyer, DL	1
Malz, CR	1
Hofmann, MH	1
Ebbesson, SO	1
Shaw, C	2
Scarth, BA	1
Ossowska, K	1
Schulze, G	1
Wolfarth, S	1
Coper, H	1
Kaminska, A	1
Hausmanowa-Petrusewicz, I	1
Potier, B	1
Rascol, O	1
Jazat, F	1
Lamour, Y	1
Dutar, P	1
Cameron, L	1
March, D	1
Cynader, M	1
Zielinski, B	1
Hendrickson, A	1
Luhmann, HJ	1
Prince, DA	1
Balcar, VJ	1
Joó, F	1
Kása, P	1
Dammasch, IE	1
Wolff, JR	1

Other Studies

38 other studies available for baclofen and Aging

Article	Year
Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats. Neuroscience, 2017, 03-14, Volume: 345 Topics: Aging; Animals; Attention; Baclofen; Discrimination Learning; Executive Function; GABA-B Receptor Ag	2017
Do baclofen pumps influence the development of scoliosis in children? Journal of neurosurgery. Pediatrics, 2010, Volume: 5, Issue:2 Topics: Adolescent; Aging; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Dystonia;	2010
Differential effects of aging on EEG after baclofen administration. Science China. Life sciences, 2011, Volume: 54, Issue:5 Topics: Aging; Animals; Baclofen; Electroencephalography; GABA-B Receptor Agonists; Male; Rats; Rats, Spragu	2011
Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body. Hearing research, 2011, Volume: 280, Issue:1-2 Topics: Aging; Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA-B R	2011
Adulthood: Life lessons. Nature, 2012, Nov-01, Volume: 491, Issue:7422 Topics: Adolescent; Adult; Aged; Aging; Animals; Autistic Disorder; Baclofen; Benzamides; Child; Humans; Imi	2012
Hippocampal Gαq/₁₁ but not Gαo-coupled receptors are altered in aging. Neuropharmacology, 2013, Volume: 70 Topics: Aging; Animals; Baclofen; CA1 Region, Hippocampal; Calcium; Excitatory Amino Acid Agonists; GABA-B R	2013
Age and monosodium glutamate treatment cause changes in the stimulation-induced [3H]-norepinephrine release from rat nucleus tractus solitarii-dorsal vagal nucleus slices. Life sciences, 2004, Feb-13, Volume: 74, Issue:13 Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Baclofen; GABA Agonists; Glutamic Acid;	2004
Increased baclofen-stimulated G protein coupling and deactivation in rat brain cortex during development. Brain research. Developmental brain research, 2004, Jul-19, Volume: 151, Issue:1-2 Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Baclofen; Cerebral Cortex; Dose-Response Rel	2004
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding. Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:7 Topics: Adrenergic beta-Agonists; Aging; Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Co	2005
Morphine withdrawal syndrome and its prevention with baclofen: Autoradiographic study of mu-opioid receptors in prepubertal male and female mice. Synapse (New York, N.Y.), 2006, Volume: 60, Issue:2 Topics: Aging; Animals; Autoradiography; Baclofen; Binding Sites; Brain; Disease Models, Animal; Enkephalin,	2006
GABAergic modulation of developing pedunculopontine nucleus. Neuroreport, 2007, Feb-12, Volume: 18, Issue:3 Topics: Action Potentials; Aging; Animals; Baclofen; GABA Agonists; GABA-B Receptor Antagonists; gamma-Amino	2007
GABAB receptor mediated inhibition of field stimulation induced contractions of detrusor muscle strips from newborn rats. Journal of autonomic pharmacology, 1984, Volume: 4, Issue:1 Topics: Aging; Animals; Animals, Newborn; Atropine; Baclofen; Electric Stimulation; Female; Hexamethonium Co	1984
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro. Life sciences, 1984, Apr-16, Volume: 34, Issue:16 Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-A	1984
Age-related changes in [3H]baclofen binding in mouse cerebellum. General pharmacology, 1995, Volume: 26, Issue:6 Topics: Age Factors; Aging; Animals; Baclofen; Binding, Competitive; Cerebellum; Cerebral Cortex; Male; Mice	1995
Baclofen, a gamma-aminobutyric acid-b receptor agonist, delays diabetes onset in the non-obese diabetic mouse. Acta diabetologica, 1995, Volume: 32, Issue:1 Topics: Aging; Animals; Baclofen; Diabetes Mellitus, Type 1; Female; GABA-B Receptor Antagonists; Glutamate	1995
Different GABAB-mediated effects on protein kinase C activity and immunoreactivity in neonatal and adult rat hippocampal slices. Journal of neurochemistry, 1995, Volume: 65, Issue:2 Topics: Aging; Animals; Baclofen; Hippocampus; Immunoblotting; In Vitro Techniques; Male; Neurons; Protein K	1995
Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development. The Journal of physiology, 1994, Nov-01, Volume: 480 ( Pt 3) Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Neuro	1994
Baclofen, a gamma-aminobutyric acid B agonist, modifies hormonal secretion in pituitary cells from infantile female rats. Life sciences, 1996, Volume: 58, Issue:13 Topics: Aging; Animals; Baclofen; Cells, Cultured; Dose-Response Relationship, Drug; Female; Follicle Stimul	1996
Age-related development of gamma-aminobutyric acid (GABA)B receptor functions in various brain regions of spontaneously hypertensive rats. Neurochemical research, 1998, Volume: 23, Issue:1 Topics: Adenylyl Cyclases; Aging; Animals; Baclofen; Brain; Corpus Striatum; Cyclic AMP; GABA Agonists; gamm	1998
Ontogenesis of presynaptic GABAB receptor-mediated inhibition in the CA3 region of the rat hippocampus. Journal of neurophysiology, 1998, Volume: 79, Issue:3 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn;	1998
Modulation of calcium by inhibitory systems in the developing auditory midbrain. Neuroscience, 1998, Volume: 83, Issue:4 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals	1998
A developmental shift from GABAergic to glycinergic transmission in the central auditory system. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jun-15, Volume: 18, Issue:12 Topics: Aging; Animals; Auditory Pathways; Baclofen; Brain; Electric Conductivity; GABA Agonists; gamma-Amin	1998
Postnatal development of GABAB receptor-mediated modulation of voltage-activated Ca2+ currents in mouse brain-stem neurons. The European journal of neuroscience, 1999, Volume: 11, Issue:7 Topics: Aging; Animals; Animals, Newborn; Baclofen; Brain Stem; Calcium Channels; Calcium Channels, L-Type;	1999
Developmental disinhibition: turning off inhibition turns on breathing in vertebrates. Journal of neurobiology, 2000, Nov-05, Volume: 45, Issue:2 Topics: Action Potentials; Aging; Animals; Baclofen; Brain Stem; Efferent Pathways; GABA Antagonists; Metamo	2000
Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats. Neuroreport, 2001, Dec-21, Volume: 12, Issue:18 Topics: Aging; Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid;	2001
Agonist-specific maturation of GIRK current responses in acutely isolated pyramidal neurons of rat neocortex. Brain research, 2002, Mar-08, Volume: 929, Issue:2 Topics: Adenosine; Aging; Animals; Animals, Newborn; Baclofen; Cellular Senescence; Electric Conductivity; G	2002
Baclofen inhibits ANP-mediated cyclic GMP synthesis in the rat cervical spinal cord. Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2 Topics: Aging; Animals; Atrial Natriuretic Factor; Baclofen; Cervical Vertebrae; Cyclic GMP; GABA Agonists;	2002
Treatment of amyotrophic lateral sclerosis. Advances in neurology, 1977, Volume: 17 Topics: Aging; Amitriptyline; Amyotrophic Lateral Sclerosis; Baclofen; Braces; Dantrolene; Deglutition Disor	1977
Changes in the effect of gamma-aminobutyric acid on prolactin secretion during sexual maturation in female rats. Endocrinology, 1992, Volume: 131, Issue:1 Topics: 4-Aminobutyrate Transaminase; Aging; Aminooxyacetic Acid; Animals; Baclofen; Female; gamma-Aminobuty	1992
The actions of 3-aminopropanephosphinic acid at GABAB receptors in rat hippocampus. European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3 Topics: Action Potentials; Aging; Animals; Baclofen; GABA Antagonists; Hippocampus; Membrane Potentials; Org	1992
Age-dependent changes in substantia nigra GABA-mediated seizure suppression. Epilepsy research. Supplement, 1992, Volume: 8 Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Dominance, Cerebral; Energy Metabolism; Flu	1992
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging". Journal fur Hirnforschung, 1992, Volume: 33, Issue:4-5 Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Fema	1992
Age-dependent regulation of GABAA receptors in neocortex. Brain research. Molecular brain research, 1992, Volume: 14, Issue:3 Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Aci	1992
Muscle stiffness and continuous electromyographic activity in old rats; an animal model for spasticity? Neuroscience, 1992, Volume: 51, Issue:1 Topics: Aging; Animals; Atrophy; Baclofen; Benserazide; Drug Combinations; Electromyography; Female; Levodop	1992
Alterations in the properties of hippocampal pyramidal neurons in the aged rat. Neuroscience, 1992, Volume: 48, Issue:4 Topics: Acetylcholine; Action Potentials; Aging; Analysis of Variance; Animals; Baclofen; Carbachol; Electri	1992
Pre- and postnatal development of GABA receptors in Macaca monkey visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:12 Topics: Aging; Animals; Animals, Newborn; Baclofen; Binding Sites; Corpus Striatum; Embryonic and Fetal Deve	1991
Postnatal maturation of the GABAergic system in rat neocortex. Journal of neurophysiology, 1991, Volume: 65, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aging; Animals; Animals, Newborn; Baclofen; Bicucull	1991
GABA receptor binding in rat cerebral cortex and superior cervical ganglion in the absence of GABAergic synapses. Neuroscience letters, 1986, May-23, Volume: 66, Issue:3 Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Binding, Competitive; Cerebral Cortex; Fema	1986