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baclofen and Acute Hypercapnic Respiratory Failure

baclofen has been researched along with Acute Hypercapnic Respiratory Failure in 19 studies

Research Excerpts

ExcerptRelevanceReference
"A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus."7.68Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. ( Demazière, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Baclofen (Lioresal) is a derivative of gamma-aminobutyric acid and is used in both adults and children mainly for symptomatic treatment of muscle spasticity."5.56Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."5.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"Intrathecal baclofen (ITB) therapy is being used increasingly to treat medically intractable spasticity in children with cerebral palsy and spinal cord injuries."3.73Intrathecal baclofen overdose and withdrawal. ( Adirim, TA; Kothare, S; Piatt, JH; Shirley, KW, 2006)
"A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus."3.68Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. ( Demazière, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Eighteen patients with severe spasticity of cerebral origin, who failed to respond adequately to more conservative treatments, have-been treated with continuous infusion of intrathecal baclofen delivered via an implanted pump."2.69Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients. ( Rawicki, B, 1999)
"Baclofen (Lioresal) is a derivative of gamma-aminobutyric acid and is used in both adults and children mainly for symptomatic treatment of muscle spasticity."1.56Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen. ( Dasgupta, K; Nielson, S, 2020)
"Baclofen is a drug used mainly to treat muscle spasticity."1.46Correlation between the single, high dose of ingested baclofen and clinical symptoms. ( Anand, JS; Biliński, P; Jaworska-Łuczak, B; Waldman, W; Wojtyła, A; Zając, M, 2017)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."1.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system."1.33Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005)
"Muscle spasticity may adversely affect pulmonary function after spinal cord injury (SCI)."1.33Baclofen pump intervention for spasticity affecting pulmonary function. ( Britton, D; Esselman, P; Goldstein, B; Jones-Redmond, J, 2005)
"There was no correlation between the dosage of baclofen and the clinical outcome."1.32[Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004)
"Three patients who had adult-onset dystonia and who were exhibiting respiratory problems were examined clinically and electrophysiologically."1.29Involvement of respiratory muscles in adult-onset dystonia: a clinical and electrophysiological study. ( Bergouignan, FX; Burbaud, P; Ferrer, X; Julien, J; Lagueny, A; Le Masson, G, 1995)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's4 (21.05)18.2507
2000's5 (26.32)29.6817
2010's5 (26.32)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Dasgupta, K1
Nielson, S1
Cai, Q1
Wu, C1
Xu, W1
Liang, Y1
Liao, S1
Mitsuboshi, S1
Anand, JS1
Zając, M1
Waldman, W1
Wojtyła, A1
Biliński, P1
Jaworska-Łuczak, B1
Chartier, M1
Tannous, S1
Benturquia, N1
Labat, L1
Reis, R1
Risède, P1
Chevillard, L1
Mégarbane, B1
Stroud, J1
Scattoloni, J1
Blasingim, M1
Nafiu, OO1
de Witte, LD1
Dekker, D1
Veraart, J1
Kromkamp, M1
Kaasjager, K1
Vinkers, CH1
Mahvash, M1
Maslehaty, H1
Warneke, N1
Doukas, A1
Petridis, AK1
Mehdorn, HM1
Chodorowski, Z2
Sein Anand, J2
Wiśniewski, M1
Burda, P1
Britton, D1
Goldstein, B1
Jones-Redmond, J1
Esselman, P1
Shirley, KW1
Kothare, S1
Piatt, JH1
Adirim, TA1
Lipscomb, DJ1
Meredith, TJ1
Lagueny, A1
Burbaud, P1
Le Masson, G1
Bergouignan, FX1
Ferrer, X1
Julien, J1
Rawicki, B1
Choo, YM1
Kim, GB1
Choi, JY1
Park, JH2
Yang, CW1
Kim, YS1
Bang, BK1
Saissy, JM1
Demazière, J1
Vitris, M1
Seck, M1
Marcoux, L1
Gaye, M1
Ndiaye, M1
Himmelsbach, FA1
Köhler, E1
Zanker, B1
Wandel, E1
Krämer, G1
Poralla, T1
Meyer zum Büschenfelde, KH1
Köhler, H1
Müller-Schwefe, G1
Penn, RD1

Trials

1 trial available for baclofen and Acute Hypercapnic Respiratory Failure

ArticleYear
Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients.
    Journal of neurosurgery, 1999, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Baclofen; Brain Injuries; Cerebral Palsy; Dystonia Musculorum Deformans; Follow-U

1999

Other Studies

18 other studies available for baclofen and Acute Hypercapnic Respiratory Failure

ArticleYear
Coma and Respiratory Failure in a 2-Year-Old Child After Accidental Overdose of Baclofen.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2020, Volume: 73, Issue:3

    Topics: Adult; Baclofen; Child, Preschool; Coma; Drug Overdose; Female; Humans; Muscle Relaxants, Central; R

2020
Stiff-person syndrome coexisting with critical illness polyneuropathy: A case report.
    Medicine, 2020, Dec-11, Volume: 99, Issue:50

    Topics: Baclofen; Clonazepam; Diagnosis, Differential; Electromyography; Humans; Immunoglobulins, Intravenou

2020
Association Between Baclofen and Respiratory Depression in Patients With Chronic Kidney Disease.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:6

    Topics: Age Factors; Aged; Baclofen; Body Weight; Female; Humans; Male; Middle Aged; Propiophenones; Renal I

2021
Correlation between the single, high dose of ingested baclofen and clinical symptoms.
    Annals of agricultural and environmental medicine : AAEM, 2017, Dec-23, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Age Factors; Baclofen; Blood Pressure; Dose-Response Relationship, Drug; Female;

2017
Baclofen-Induced Neuro-Respiratory Toxicity in the Rat: Contribution of Tolerance and Characterization of Withdrawal Syndrome.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 07-01, Volume: 164, Issue:1

    Topics: Animals; Baclofen; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Male; Neurotoxicity Synd

2018
Intrathecal baclofen toxicity: an unusual cause of paediatric postoperative coma and respiratory depression.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:6

    Topics: Adolescent; Baclofen; Cerebral Palsy; Coma; Humans; Injections, Spinal; Male; Muscle Relaxants, Cent

2014
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
    Nederlands tijdschrift voor geneeskunde, 2016, Volume: 160

    Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans;

2016
Potential correlation of intrathecal baclofen concentration and clinical improvement after high dose intrathecal intoxication: a case report.
    Clinical neurology and neurosurgery, 2011, Volume: 113, Issue:9

    Topics: Baclofen; Critical Care; Drainage; Humans; Hypoxia, Brain; Infusion Pumps; Injections, Spinal; Male;

2011
[Acute intoxication with baclofen].
    Przeglad lekarski, 2004, Volume: 61, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist

2004
Selected clinical aspects of acute intoxication with baclofen.
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal

2005
Baclofen pump intervention for spasticity affecting pulmonary function.
    The journal of spinal cord medicine, 2005, Volume: 28, Issue:4

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Lung; Male; Middle Aged; Muscle R

2005
Intrathecal baclofen overdose and withdrawal.
    Pediatric emergency care, 2006, Volume: 22, Issue:4

    Topics: Baclofen; Cerebral Palsy; Child; Drug Overdose; Humans; Infusion Pumps, Implantable; Injections, Spi

2006
Baclofen overdose.
    Postgraduate medical journal, 1980, Volume: 56, Issue:652

    Topics: Baclofen; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged; Muscle Hypotonia; Respiratory Insuffi

1980
Involvement of respiratory muscles in adult-onset dystonia: a clinical and electrophysiological study.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:6

    Topics: Administration, Oral; Aged; Baclofen; Botulinum Toxins; Delayed-Action Preparations; Diaphragm; Dyst

1995
Severe respiratory depression by low-dose baclofen in the treatment of chronic hiccups in a patient undergoing CAPD.
    Nephron, 2000, Volume: 86, Issue:4

    Topics: Aged; Baclofen; Chronic Disease; GABA Agonists; Hiccup; Humans; Male; Peritoneal Dialysis, Continuou

2000
Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation.
    Intensive care medicine, 1992, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Africa; Age Factors; Aged; Baclofen; Blood Gas Analysis; Coma; Creatine Kinase; D

1992
[Baclofen intoxication in chronic hemodialysis and kidney transplantation].
    Deutsche medizinische Wochenschrift (1946), 1992, May-08, Volume: 117, Issue:19

    Topics: Adult; Baclofen; Female; Graft Rejection; Humans; Kidney Transplantation; Male; Middle Aged; Neuroco

1992
Physostigmine in the treatment of intrathecal baclofen overdose. Report of three cases.
    Journal of neurosurgery, 1989, Volume: 71, Issue:2

    Topics: Adult; Baclofen; Coma; Humans; Injections, Spinal; Male; Middle Aged; Physostigmine; Respiratory Ins

1989