baclofen has been researched along with Acute Disease in 27 studies
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Baclofen, a specific GABA(B) receptor agonist, is used to treat spasticity and its off-label use includes the treatment of pain." | 7.75 | Role of GABA(B) receptor agonist baclofen in acute pain modulation during the early postnatal period. ( Franek, M; Vaculin, S, 2009) |
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 7.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| "After repair of the catheter of an implanted intrathecal baclofen (ITB) delivery system, a 17-year-old man with cerebral palsy developed acute lower-extremity hypotonia." | 7.71 | Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. ( Murphy, NA, 2002) |
| "Our patient is a 19-year-old girl with cerebral palsy secondary to prematurity and repaired tetralogy of Fallot who had started oral baclofen 8 months before to diminish spasticity." | 3.80 | Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity. ( Hoon, A; Johnston, M; Ogborn, J; Srivastava, S, 2014) |
| "Baclofen, a specific GABA(B) receptor agonist, is used to treat spasticity and its off-label use includes the treatment of pain." | 3.75 | Role of GABA(B) receptor agonist baclofen in acute pain modulation during the early postnatal period. ( Franek, M; Vaculin, S, 2009) |
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 3.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| "After repair of the catheter of an implanted intrathecal baclofen (ITB) delivery system, a 17-year-old man with cerebral palsy developed acute lower-extremity hypotonia." | 3.71 | Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. ( Murphy, NA, 2002) |
| "Baclofen has been reported in uncontrolled clinical studies to reduce craving for abused drugs and reduce their rewarding effects." | 2.70 | Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. ( Cousins, MS; de Wit, H; Stamat, HM, 2001) |
| "One patient developed withdrawal symptoms after baclofen was stopped, and the other developed a manic attach while receiving the drug." | 2.37 | Baclofen-induced psychosis: two cases and a review. ( Iskandar, HL; Yassa, RY, 1988) |
| "Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system." | 1.33 | Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005) |
| "There was no correlation between the dosage of baclofen and the clinical outcome." | 1.32 | [Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004) |
| "Baclofen has both presynaptic and postsynaptic effects." | 1.31 | gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension. ( Mifflin, SW; Vitela, M, 2001) |
| "We report a case of acute transient encephalopathy with confusion, drowsiness, myoclonic jerks, periodic triphasic sharp wave EEG patterns induced by low doses of baclofen." | 1.28 | Acute transient cerebral intoxication induced by low doses of baclofen. ( Lazzarino, LG; Nicolai, A; Valassi, F, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.11) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 16 (59.26) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Srivastava, S | 1 |
| Hoon, A | 1 |
| Ogborn, J | 1 |
| Johnston, M | 1 |
| Hetzler, BE | 1 |
| Ondracek, JM | 1 |
| Becker, EA | 1 |
| Franek, M | 1 |
| Vaculin, S | 1 |
| Ross, JC | 1 |
| Cook, AM | 1 |
| Stewart, GL | 1 |
| Fahy, BG | 1 |
| Macaigne, G | 1 |
| Champagnon, N | 1 |
| Harnois, F | 1 |
| Cheiab, S | 1 |
| Chayette, C | 1 |
| Murphy, NA | 1 |
| Meythaler, JM | 1 |
| Roper, JF | 1 |
| Brunner, RC | 1 |
| Bardutzky, J | 1 |
| Tronnier, V | 1 |
| Schwab, S | 1 |
| Meinck, HM | 1 |
| Li, Y | 1 |
| Li, X | 1 |
| Harvey, PJ | 1 |
| Bennett, DJ | 1 |
| Chodorowski, Z | 2 |
| Sein Anand, J | 2 |
| Wiśniewski, M | 1 |
| Ackland, GL | 1 |
| Fox, R | 1 |
| Burda, P | 1 |
| Potes, CS | 1 |
| Neto, FL | 1 |
| Castro-Lopes, JM | 1 |
| Duhon, BS | 1 |
| MacDonald, JD | 1 |
| Goniewicz, J | 1 |
| Macheta, A | 1 |
| Smiałek, J | 1 |
| Dalvi, A | 1 |
| Fahn, S | 1 |
| Ford, B | 1 |
| Shiah, IS | 1 |
| Yatham, LN | 1 |
| Lam, RW | 1 |
| Tam, EM | 1 |
| Zis, AP | 1 |
| Brown, LK | 1 |
| Heffner, JE | 1 |
| Obbens, EA | 1 |
| Vitela, M | 1 |
| Mifflin, SW | 1 |
| Cousins, MS | 1 |
| Stamat, HM | 1 |
| de Wit, H | 1 |
| Cuny, E | 1 |
| Richer, E | 1 |
| Castel, JP | 1 |
| O'Rourke, F | 1 |
| Steinberg, R | 1 |
| Ghosh, P | 1 |
| Khan, S | 1 |
| Silbert, PL | 1 |
| Stewart-Wynne, EG | 1 |
| Lazzarino, LG | 1 |
| Nicolai, A | 1 |
| Valassi, F | 1 |
| Saltuari, L | 1 |
| Baumgartner, H | 1 |
| Kofler, M | 1 |
| Schmutzhard, E | 1 |
| Russegger, L | 1 |
| Aichner, F | 1 |
| Gerstenbrand, F | 1 |
| Yassa, RY | 1 |
| Iskandar, HL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlling Hyperadrenergic Activity in Neurologic Injury[NCT01343329] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to Unable to enroll subjects that fit study criteria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for baclofen and Acute Disease
| Article | Year |
|---|---|
Acute intrathecal baclofen withdrawal: a brief review of treatment options.
Topics: Acute Disease; Baclofen; Female; Humans; Injections, Spinal; Middle Aged; Muscle Relaxants, Central; | 2011 |
Baclofen-induced psychosis: two cases and a review.
Topics: Acute Disease; Adult; Aged; Baclofen; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Humans; Ma | 1988 |
2 trials available for baclofen and Acute Disease
| Article | Year |
|---|---|
Growth hormone response to baclofen in patients with mania: a pilot study.
Topics: Acute Disease; Adult; Area Under Curve; Baclofen; Bipolar Disorder; Female; GABA Agonists; GABA-B Re | 1999 |
Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking.
Topics: Acute Disease; Adult; Affect; Baclofen; Dose-Response Relationship, Drug; Double-Blind Method; Femal | 2001 |
23 other studies available for baclofen and Acute Disease
| Article | Year |
|---|---|
Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity.
Topics: Acute Disease; Adult; Baclofen; Cerebral Palsy; Dose-Response Relationship, Drug; Female; GABA-B Rec | 2014 |
Baclofen does not counteract the acute effects of ethanol on flash-evoked potentials in Long-Evans rats.
Topics: Acute Disease; Alcohol-Induced Disorders, Nervous System; Animals; Arousal; Baclofen; Drug Synergism | 2008 |
Role of GABA(B) receptor agonist baclofen in acute pain modulation during the early postnatal period.
Topics: Acute Disease; Age Factors; Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, D | 2009 |
Baclofen-induced acute hepatitis in alcohol-dependent patient.
Topics: Acute Disease; Alcoholism; Baclofen; Chemical and Drug Induced Liver Injury; Female; GABA-B Receptor | 2011 |
Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report.
Topics: Acute Disease; Adolescent; Baclofen; Cerebral Palsy; Humans; Injections, Spinal; Leg; Male; Muscle H | 2002 |
Cyproheptadine for intrathecal baclofen withdrawal.
Topics: Acute Disease; Adult; Baclofen; Cerebral Palsy; Cyproheptadine; Diagnosis, Differential; Female; Fev | 2003 |
Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage.
Topics: Acute Disease; Adult; Baclofen; Catheterization; Equipment Failure; Humans; Hypertension; Infusion P | 2003 |
Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity.
Topics: Acute Disease; Animals; Baclofen; Chronic Disease; Excitatory Postsynaptic Potentials; Female; GABA | 2004 |
[Acute intoxication with baclofen].
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist | 2004 |
Low-dose propofol infusion for controlling acute hyperspasticity after withdrawal of intrathecal baclofen therapy.
Topics: Acute Disease; Adult; Aged; Baclofen; Drug Hypersensitivity; Humans; Injections, Spinal; Male; Muscl | 2005 |
Selected clinical aspects of acute intoxication with baclofen.
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal | 2005 |
Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.
Topics: Acute Disease; Analgesics; Animals; Baclofen; Behavior, Animal; Chronic Disease; Disease Models, Ani | 2006 |
Infusion of intrathecal baclofen for acute withdrawal. Technical note.
Topics: Acute Disease; Adult; Analgesia, Patient-Controlled; Baclofen; Humans; Infusion Pumps, Implantable; | 2007 |
[Acute baclofen poisoning].
Topics: Acute Disease; Adolescent; Adult; Baclofen; Critical Care; Female; Humans; Male; Resuscitation | 1981 |
[Two cases of acute intoxication with beta-amino-methyl-P-chlorhydroacrylic acid (author's transl)].
Topics: Acute Disease; Adult; Baclofen; Humans; Male; Suicide, Attempted | 1980 |
Intrathecal baclofen in the treatment of dystonic storm.
Topics: Acute Disease; Adolescent; Baclofen; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1998 |
Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen.
Topics: Acute Disease; Antiparkinson Agents; Baclofen; Electromyography; Electrooculography; Humans; Injecti | 2000 |
gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension.
Topics: Acute Disease; Animals; Baclofen; Blood Pressure; Chronic Disease; Denervation; GABA Agonists; Hyper | 2001 |
Dysautonomia syndrome in the acute recovery phase after traumatic brain injury: relief with intrathecal Baclofen therapy.
Topics: Acute Disease; Adolescent; Adult; Autonomic Nervous System Diseases; Baclofen; Brain Injuries; GABA | 2001 |
Withdrawal of baclofen may cause acute confusion in elderly patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Baclofen; Confusion; GABA Agonists; Humans; Male; Muscle Rel | 2001 |
Surgical procedures for the relief of acute and chronic pain: caution about intermittent intrathecal injection.
Topics: Acute Disease; Analgesia, Epidural; Baclofen; Chronic Disease; Humans; Infusion Pumps, Implantable; | 1992 |
Acute transient cerebral intoxication induced by low doses of baclofen.
Topics: Acute Disease; Aged; Baclofen; Brain Diseases; Electroencephalography; Evoked Potentials, Auditory, | 1991 |
Failure of physostigmine in treatment of acute severe intrathecal baclofen intoxication.
Topics: Acute Disease; Adolescent; Baclofen; Humans; Injections, Spinal; Male; Paraplegia; Physostigmine | 1990 |