bacampicillin and Scarlet-Fever

Clinical study on bacampicillin (BAPC) granules was performed in 20 children with infectious diseases. Patients treated with BAPC granules were 10 cases of scarlet fever, 3 cases of pertussis, 3 cases of Salmonella enteritis and 4 cases of acute enteritis. Clinical results were excellent in 2, good in 9, fair in 3, poor in 4 and unknown in 2. No side effect was observed.

Topics: Acute Disease; Ampicillin; Child; Child, Preschool; Dosage Forms; Enteritis; Female; Humans; Infant; Male; Salmonella Infections; Scarlet Fever; Whooping Cough

We investigated bacampicillin (BAPC) granules in the field of pediatrics. 1) Average serum levels after administration of BAPC granules at a dose of 10 mg/kg as ABPC were 6.8 mug/ml at 1 hour, 1.4 mug/ml at 6 hours. Average urinary excretion rate till 6 hours was 84.5%. Those results were almost same as those obtained with BAPC tablet. 2) We treated patients with acute tonsillitis, lacunar tonsillitis and acute bronchitis by BAPC granules at a dose of 30 approximately 40 mg potency/kg for 3 approximately 5 days, and excellent results were obtained. 3) In the case of streptococcal infections including scarlet fever, pharyngeal streptococci disappeared 1 approximately 2 days after administration and did not reappeared. 4) BAPC granules were easy to intake for children and no abnormal laboratory finding was observed. 5) BAPC granules seem to be useful for treatment of pediatric infections.

Topics: Acute Disease; Ampicillin; Bronchitis; Dosage Forms; Humans; Scarlet Fever; Tonsillitis