aztreonam has been researched along with Stevens-Johnson Syndrome in 1 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aztreonam was discontinued in both patients." | 1.28 | Toxic epidermal necrolysis possibly linked to aztreonam in bone marrow transplant patients. ( Bianco, JA; McDonald, BJ; Singer, JW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McDonald, BJ | 1 |
| Singer, JW | 1 |
| Bianco, JA | 1 |
1 other study available for aztreonam and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Toxic epidermal necrolysis possibly linked to aztreonam in bone marrow transplant patients.
Topics: Adult; Aztreonam; Bacterial Infections; Bone Marrow Transplantation; Graft vs Host Disease; Humans; | 1992 |