aztreonam has been researched along with Peritonitis in 18 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty six patients who developed 48 episodes of peritonitis while on CAPD were randomised to receive either oral ofloxacin or intraperitoneal (i." | 9.07 | A randomised prospective comparison of oral ofloxacin and intraperitoneal vancomycin plus aztreonam in the treatment of bacterial peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD). ( Chan, CY; Cheng, IK; Wong, WT, 1991) |
| "Aztreonam and cefotaxime were compared in 44 cirrhotic patients who had 52 episodes of gram-negative spontaneous peritonitis." | 9.07 | Aztreonam vs. cefotaxime in the treatment of gram-negative spontaneous peritonitis in cirrhotic patients. ( Alonso, T; Ariza, J; Esteve, M; Fernández Bañeres, F; Gudiol, F; Liñares, J; Xiol, X, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 9.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "The purpose of this study was to investigate aztreonam (ATM) and avibactam (AVI) distribution in intraperitoneal fluid and muscle interstitial fluid by microdialysis in rats, with or without peritonitis, and to compare the unbound concentrations in tissue with the unbound concentrations in blood." | 7.88 | Microdialysis Study of Aztreonam-Avibactam Distribution in Peritoneal Fluid and Muscle of Rats with or without Experimental Peritonitis. ( Adier, C; Chauzy, A; Couet, W; Lamarche, I; Marchand, S, 2018) |
| "The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic." | 7.69 | Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994) |
| "The pharmacokinetics of aztreonam and vancomycin were studied in six adult patients who developed peritonitis during Continuous Ambulatory Peritoneal Dialysis." | 7.68 | Pharmacokinetics of once daily intra-peritoneal aztreonam and vancomycin in the treatment of CAPD peritonitis. ( Altmann, P; Brown, J; Cunningham, J; Marsh, F; Shaw, E, 1990) |
| "Aztreonam (AZT) was evaluated for its clinical efficacy in 6 patients with pelvic peritonitis." | 7.67 | [Clinical efficacy of aztreonam in pelvic peritonitis]. ( Abe, Y; Funaki, K; Nakakuki, M; Okamura, K; Yamada, K, 1985) |
| " administration of aztreonam (A) and cefuroxime (C), 10 adult CAPD patients (pts) with peritonitis were trained to start the following treatment procedure: a) sterile collection of dialysate effluent for cultures; b) 4 rapid in-and-out exchanges with antibiotic free dialysate; c) addition of 2 g C and 2 g A to a 2-L exchange for 6-h dwell time (the same dosage was repeated once a day in the overnight exchange); d) routine CAPD exchanges." | 5.28 | Effectiveness of single daily intraperitoneal administration of aztreonam and cefuroxime in the treatment of peritonitis in continuous ambulatory peritoneal dialysis (CAPD). ( Conte, G; Fuiano, G; Nani, E; Sepe, V; Viscione, M, 1989) |
| "Forty six patients who developed 48 episodes of peritonitis while on CAPD were randomised to receive either oral ofloxacin or intraperitoneal (i." | 5.07 | A randomised prospective comparison of oral ofloxacin and intraperitoneal vancomycin plus aztreonam in the treatment of bacterial peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD). ( Chan, CY; Cheng, IK; Wong, WT, 1991) |
| "Aztreonam and cefotaxime were compared in 44 cirrhotic patients who had 52 episodes of gram-negative spontaneous peritonitis." | 5.07 | Aztreonam vs. cefotaxime in the treatment of gram-negative spontaneous peritonitis in cirrhotic patients. ( Alonso, T; Ariza, J; Esteve, M; Fernández Bañeres, F; Gudiol, F; Liñares, J; Xiol, X, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 5.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "The purpose of this study was to investigate aztreonam (ATM) and avibactam (AVI) distribution in intraperitoneal fluid and muscle interstitial fluid by microdialysis in rats, with or without peritonitis, and to compare the unbound concentrations in tissue with the unbound concentrations in blood." | 3.88 | Microdialysis Study of Aztreonam-Avibactam Distribution in Peritoneal Fluid and Muscle of Rats with or without Experimental Peritonitis. ( Adier, C; Chauzy, A; Couet, W; Lamarche, I; Marchand, S, 2018) |
| "The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic." | 3.69 | Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994) |
| "The pharmacokinetics of aztreonam and vancomycin were studied in six adult patients who developed peritonitis during Continuous Ambulatory Peritoneal Dialysis." | 3.68 | Pharmacokinetics of once daily intra-peritoneal aztreonam and vancomycin in the treatment of CAPD peritonitis. ( Altmann, P; Brown, J; Cunningham, J; Marsh, F; Shaw, E, 1990) |
| " The protective effect of cefotaxime, aztreonam and gentamicin in peritonitis induced by E." | 3.67 | Effect of Bacteroides fragilis on mortality induced by Escherichia coli in an experimental infection treated with cefotaxime, aztreonam or gentamicin. ( Castilla, C; Ponte, C; Santamaría, M; Soriano, F, 1989) |
| "Aztreonam (AZT) was evaluated for its clinical efficacy in 6 patients with pelvic peritonitis." | 3.67 | [Clinical efficacy of aztreonam in pelvic peritonitis]. ( Abe, Y; Funaki, K; Nakakuki, M; Okamura, K; Yamada, K, 1985) |
| " An adequate standard dosage of aztreonam could be established as 3-4 g/day in compromised patients, and it should be combined with gram-positive coverage when used empirically." | 2.66 | A multicenter comparative trial of aztreonam in the treatment of gram-negative infections in compromised intensive-care patients. ( Bosch-Perez, A; Rabinad, E, 1989) |
| "Aztreonam is a monobactam antibiotic with a broad antimicrobial spectrum against Gram-negative facultative bacteria." | 2.37 | Aztreonam in treatment of intra-abdominal infections. ( Malangoni, MA, 1988) |
| " administration of aztreonam (A) and cefuroxime (C), 10 adult CAPD patients (pts) with peritonitis were trained to start the following treatment procedure: a) sterile collection of dialysate effluent for cultures; b) 4 rapid in-and-out exchanges with antibiotic free dialysate; c) addition of 2 g C and 2 g A to a 2-L exchange for 6-h dwell time (the same dosage was repeated once a day in the overnight exchange); d) routine CAPD exchanges." | 1.28 | Effectiveness of single daily intraperitoneal administration of aztreonam and cefuroxime in the treatment of peritonitis in continuous ambulatory peritoneal dialysis (CAPD). ( Conte, G; Fuiano, G; Nani, E; Sepe, V; Viscione, M, 1989) |
| "Aztreonam was given i." | 1.27 | Aztreonam in the treatment of serious gram-negative infections in the elderly. ( Deger, F; Douchamps, J; Freschi, E; Herchuelz, A; Nève, P; Thys, JP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Tobudic, S | 1 |
| Prager, I | 1 |
| Kussmann, M | 1 |
| Obermüller, M | 1 |
| Ursli, M | 1 |
| Zeitlinger, M | 1 |
| Wiesholzer, M | 1 |
| Burgmann, H | 1 |
| Poeppl, W | 1 |
| Reznicek, G | 1 |
| Chauzy, A | 1 |
| Lamarche, I | 1 |
| Adier, C | 1 |
| Couet, W | 1 |
| Marchand, S | 1 |
| Hortling, L | 1 |
| Sipilä, R | 1 |
| Sawyer, RG | 1 |
| Adams, RB | 1 |
| Pruett, TL | 1 |
| Finch, RC | 1 |
| Holliday, AP | 1 |
| Innes, A | 1 |
| Burden, RP | 1 |
| Morgan, AG | 1 |
| Shaw, PN | 1 |
| Harding, I | 1 |
| Wale, MC | 1 |
| Chimura, T | 1 |
| Ise, H | 1 |
| Misawa, H | 1 |
| Cheng, IK | 1 |
| Chan, CY | 1 |
| Wong, WT | 1 |
| Ariza, J | 1 |
| Xiol, X | 1 |
| Esteve, M | 1 |
| Fernández Bañeres, F | 1 |
| Liñares, J | 1 |
| Alonso, T | 1 |
| Gudiol, F | 1 |
| Gould, FK | 1 |
| Venning, MC | 1 |
| Ford, M | 1 |
| Brown, J | 1 |
| Altmann, P | 1 |
| Cunningham, J | 1 |
| Shaw, E | 1 |
| Marsh, F | 1 |
| Fuiano, G | 1 |
| Sepe, V | 1 |
| Viscione, M | 1 |
| Nani, E | 1 |
| Conte, G | 1 |
| Rabinad, E | 1 |
| Bosch-Perez, A | 1 |
| Soriano, F | 1 |
| Ponte, C | 1 |
| Santamaría, M | 1 |
| Castilla, C | 1 |
| Dratwa, M | 1 |
| Glupczynski, Y | 1 |
| Lameire, N | 1 |
| Matthys, D | 1 |
| Verschraegen, G | 1 |
| van Eeckhoute, M | 1 |
| Boelaert, J | 1 |
| Schurgers, M | 1 |
| van Landuyt, H | 1 |
| Verbeelen, D | 1 |
| Malangoni, MA | 1 |
| Deger, F | 1 |
| Douchamps, J | 1 |
| Freschi, E | 1 |
| Thys, JP | 1 |
| Nève, P | 1 |
| Herchuelz, A | 1 |
| Berne, TV | 1 |
| Yellin, AE | 1 |
| Appleman, MD | 1 |
| Gill, MA | 1 |
| Chenella, FC | 1 |
| Heseltine, PN | 1 |
| Okamura, K | 1 |
| Nakakuki, M | 1 |
| Yamada, K | 1 |
| Abe, Y | 1 |
| Funaki, K | 1 |
1 review available for aztreonam and Peritonitis
| Article | Year |
|---|---|
Aztreonam in treatment of intra-abdominal infections.
Topics: Abdomen; Abscess; Animals; Aztreonam; Drug Therapy, Combination; Humans; Peritonitis; Tissue Distrib | 1988 |
5 trials available for aztreonam and Peritonitis
| Article | Year |
|---|---|
A randomised prospective comparison of oral ofloxacin and intraperitoneal vancomycin plus aztreonam in the treatment of bacterial peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD).
Topics: Administration, Oral; Aztreonam; Bacterial Infections; Drug Therapy, Combination; Humans; Ofloxacin; | 1991 |
Aztreonam vs. cefotaxime in the treatment of gram-negative spontaneous peritonitis in cirrhotic patients.
Topics: Adult; Aged; Ascitic Fluid; Aztreonam; Bacterial Infections; Cefotaxime; Female; Gram-Negative Bacte | 1991 |
A multicenter comparative trial of aztreonam in the treatment of gram-negative infections in compromised intensive-care patients.
Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Bacterial Infecti | 1989 |
Aztreonam in CAPD peritonitis.
Topics: Aztreonam; Bacterial Infections; Clinical Trials as Topic; Gram-Negative Bacteria; Humans; Peritonea | 1987 |
Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin.
Topics: Adult; Appendicitis; Aztreonam; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Drug The | 1987 |
12 other studies available for aztreonam and Peritonitis
| Article | Year |
|---|---|
Compatibility of aztreonam in four commercial peritoneal dialysis fluids.
Topics: Anti-Bacterial Agents; Aztreonam; Dialysis Solutions; Drug Administration Routes; Humans; Peritoneal | 2020 |
Microdialysis Study of Aztreonam-Avibactam Distribution in Peritoneal Fluid and Muscle of Rats with or without Experimental Peritonitis.
Topics: Animals; Ascitic Fluid; Azabicyclo Compounds; Aztreonam; Male; Microdialysis; Muscle, Skeletal; Peri | 2018 |
Multiresistant Serratia marcescens peritonitis in a patient on continuous ambulatory peritoneal dialysis (CAPD) successfully treated with Azthreonam (S26,776) a new monobactam antibiotic.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Drug Resistance, Microbial; Humans; M | 1984 |
Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation.
Topics: Abdominal Abscess; Animals; Aztreonam; Bacteroides fragilis; Bacteroides Infections; beta-Lactam Res | 1994 |
Pharmacokinetic behavior of intraperitoneal teicoplanin during treatment of peritonitis complicating continuous ambulatory peritoneal dialysis.
Topics: Anti-Bacterial Agents; Aztreonam; Dialysis Solutions; Humans; Monobactams; Peritoneal Dialysis, Cont | 1996 |
[In vitro study on efficacy of combination use of aspoxicillin and beta-lactam preparations (ceftazidime, cefmetazole and aztreonam) against bacteria isolated from abdominal infections].
Topics: Amoxicillin; Anti-Bacterial Agents; Aztreonam; Bacteria; Bacterial Infections; beta-Lactamases; Bili | 1992 |
Successful treatment with chloramphenicol of Pseudomonas mesophilica peritonitis not responding to aztreonam and gentamicin.
Topics: Aged; Aztreonam; Chloramphenicol; Gentamicins; Humans; Male; Peritonitis; Pseudomonas Infections | 1990 |
Pharmacokinetics of once daily intra-peritoneal aztreonam and vancomycin in the treatment of CAPD peritonitis.
Topics: Aztreonam; Humans; Injections, Intraperitoneal; Kidney Failure, Chronic; Middle Aged; Peritoneal Dia | 1990 |
Effectiveness of single daily intraperitoneal administration of aztreonam and cefuroxime in the treatment of peritonitis in continuous ambulatory peritoneal dialysis (CAPD).
Topics: Aztreonam; Cefuroxime; Drug Administration Schedule; Drug Therapy, Combination; Evaluation Studies a | 1989 |
Effect of Bacteroides fragilis on mortality induced by Escherichia coli in an experimental infection treated with cefotaxime, aztreonam or gentamicin.
Topics: Animals; Aztreonam; Bacteroides fragilis; Bacteroides Infections; Cefotaxime; Escherichia coli Infec | 1989 |
Aztreonam in the treatment of serious gram-negative infections in the elderly.
Topics: Aged; Aged, 80 and over; Aztreonam; Bacterial Infections; Female; Gram-Negative Aerobic Bacteria; Hu | 1988 |
[Clinical efficacy of aztreonam in pelvic peritonitis].
Topics: Adult; Aztreonam; Drug Evaluation; Female; Humans; Middle Aged; Pelvis; Peritonitis; Pregnancy; Puer | 1985 |