aztreonam has been researched along with Perforated Appendicitis in 2 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 9.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 5.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barboza, E | 1 |
| del Castillo, M | 1 |
| Yi, A | 1 |
| Gotuzzo, E | 1 |
| Berne, TV | 1 |
| Yellin, AE | 1 |
| Appleman, MD | 1 |
| Gill, MA | 1 |
| Chenella, FC | 1 |
| Heseltine, PN | 1 |
2 trials available for aztreonam and Perforated Appendicitis
| Article | Year |
|---|---|
Clindamycin plus amikacin versus clindamycin plus aztreonam in established intraabdominal infections.
Topics: Abdomen; Abscess; Adult; Amikacin; Appendicitis; Aztreonam; Bacterial Infections; Clindamycin; Drug | 1994 |
Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin.
Topics: Adult; Appendicitis; Aztreonam; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Drug The | 1987 |