aztreonam has been researched along with Pachymeningitis in 18 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "10 patients with meningitis due to unusual gram-negative organisms (Pseudomonas, Proteus, Salmonella and Klebsiella) were effectively treated with aztreonam." | 7.68 | Aztreonam for treating meningitis caused by gram-negative rods. ( Bishay, E; Farid, Z; Girgis, N; Kilpatrick, M, 1991) |
| "The monobactam aztreonam was used to treat 22 young patients with meningitis caused by gram-negative bacilli." | 7.67 | Aztreonam in the treatment of bacterial meningitis. ( Ayroza-Galvão, PA; Barbosa Júnior, SP; Cavalcante, NJ; Lorenco, R; Maassen, S; Martino, MD; Milstein-Kuschnaroff, TM; Mimica, IM; Mimica, LM, 1989) |
| "This study examined the penetration of aztreonam into the cerebrospinal fluid (CSF) and brain in noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa." | 7.67 | Penetration of aztreonam into cerebrospinal fluid and brain of noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa. ( Bodem, CR; Laun, PR; Strausbaugh, LJ, 1986) |
| "A monotherapy of aztreonam (AZT) was applied to 9 male and 3 female pediatric patients of ages ranging from 2 months to 8 years and 11 months with serious purulent meningitis." | 7.67 | [Clinical evaluation of aztreonam against pediatric purulent meningitis]. ( Fujii, R; Furukawa, S; Haruta, T; Kitamura, I; Kobayashi, Y; Meguro, H; Nishimura, T; Ogura, H; Okada, T; Toyonaga, Y, 1988) |
| "The penetration of aztreonam into the cerebrospinal fluid was determined in 16 patients with bacterial meningitis undergoing treatment with other antibiotics." | 7.67 | Penetration of aztreonam into cerebrospinal fluid of patients with bacterial meningitis. ( Decazes, JM; Meulemans, A; Modai, J; Vittecoq, D; Wolff, M, 1986) |
| "The penetration of aztreonam into cerebrospinal fluid was 7 to 15% and 9 to 25%, respectively, in experimental Haemophilus influenzae type b and Escherichia coli K1 meningitis." | 7.67 | Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1. ( McCracken, GH; Olsen, KD; Sakata, Y, 1985) |
| "Aztreonam (SQ 26,776), a new monocyclic beta-lactam agent, was compared with ampicillin, ampicillin plus chloramphenicol, and gentamicin in rabbits with experimental meningitis induced by, respectively, ampicillin-susceptible Haemophilus influenzae, ampicillin-resistant H." | 7.66 | Evaluation of aztreonam in experimental bacterial meningitis and cerebritis. ( Brodeur, JP; Foresman, P; Gratz, JC; Rodeheaver, G; Scheld, WM, 1983) |
| "10 patients with meningitis due to unusual gram-negative organisms (Pseudomonas, Proteus, Salmonella and Klebsiella) were effectively treated with aztreonam." | 3.68 | Aztreonam for treating meningitis caused by gram-negative rods. ( Bishay, E; Farid, Z; Girgis, N; Kilpatrick, M, 1991) |
| "Aztreonam was administered to 20 children diagnosed as having any of the following infections: urinary tract infection, pneumonia, meningitis, and abscess of the appendix." | 3.67 | Aztreonam in the treatment of aerobic, gram-negative bacillary infections in pediatric patients. ( Arango, A; Benítez, G; Castrillón, AL; Harry, N; Mejía, GI; Restrepo, F; Trujillo, H, 1989) |
| "The monobactam aztreonam was used to treat 22 young patients with meningitis caused by gram-negative bacilli." | 3.67 | Aztreonam in the treatment of bacterial meningitis. ( Ayroza-Galvão, PA; Barbosa Júnior, SP; Cavalcante, NJ; Lorenco, R; Maassen, S; Martino, MD; Milstein-Kuschnaroff, TM; Mimica, IM; Mimica, LM, 1989) |
| "This study examined the penetration of aztreonam into the cerebrospinal fluid (CSF) and brain in noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa." | 3.67 | Penetration of aztreonam into cerebrospinal fluid and brain of noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa. ( Bodem, CR; Laun, PR; Strausbaugh, LJ, 1986) |
| "A monotherapy of aztreonam (AZT) was applied to 9 male and 3 female pediatric patients of ages ranging from 2 months to 8 years and 11 months with serious purulent meningitis." | 3.67 | [Clinical evaluation of aztreonam against pediatric purulent meningitis]. ( Fujii, R; Furukawa, S; Haruta, T; Kitamura, I; Kobayashi, Y; Meguro, H; Nishimura, T; Ogura, H; Okada, T; Toyonaga, Y, 1988) |
| "The penetration of aztreonam into the cerebrospinal fluid was determined in 16 patients with bacterial meningitis undergoing treatment with other antibiotics." | 3.67 | Penetration of aztreonam into cerebrospinal fluid of patients with bacterial meningitis. ( Decazes, JM; Meulemans, A; Modai, J; Vittecoq, D; Wolff, M, 1986) |
| "The penetration of aztreonam into cerebrospinal fluid was 7 to 15% and 9 to 25%, respectively, in experimental Haemophilus influenzae type b and Escherichia coli K1 meningitis." | 3.67 | Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1. ( McCracken, GH; Olsen, KD; Sakata, Y, 1985) |
| "The penetration of aztreonam (AZT), a new synthetic monobactam, into cerebrospinal fluid (CSF) and the clinical studies for bacterial infections were carried out." | 3.67 | [Clinical evaluation on aztreonam in pediatric field and fundamental study on its penetration into cerebrospinal fluid]. ( Furukawa, S; Okada, T, 1985) |
| "Aztreonam (SQ 26,776), a new monocyclic beta-lactam agent, was compared with ampicillin, ampicillin plus chloramphenicol, and gentamicin in rabbits with experimental meningitis induced by, respectively, ampicillin-susceptible Haemophilus influenzae, ampicillin-resistant H." | 3.66 | Evaluation of aztreonam in experimental bacterial meningitis and cerebritis. ( Brodeur, JP; Foresman, P; Gratz, JC; Rodeheaver, G; Scheld, WM, 1983) |
| "Aztreonam was administered to 25 neonates (16 term, 9 premature) with clinically and bacteriologically proved gram-negative infections." | 1.28 | Successful response of severe neonatal gram-negative infection to treatment with aztreonam. ( Constantopoulos, A; Loupa, H; Papoulias, G; Thomaidou, L, 1989) |
| "Aztreonam was administered as a single, 2-g intravenous dose to 25 patients with noninflamed meninges and to 9 patients with inflamed meninges." | 1.27 | Penetration of aztreonam into cerebrospinal fluid of patients with and without inflamed meninges. ( Baggett, JW; Berry, AJ; Duma, RJ; Platt, TB; Smith, SM; Swabb, EA, 1984) |
| "Aztreonam is a monocyclic beta-lactam antibiotic that inhibits aerobic gram-negative bacilli, including beta-lactamase-producing species." | 1.27 | Current state of infectious diseases--potential areas of directed therapy with aztreonam. ( Neu, HC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheld, WM | 1 |
| Brodeur, JP | 1 |
| Gratz, JC | 1 |
| Foresman, P | 1 |
| Rodeheaver, G | 1 |
| Duma, RJ | 1 |
| Berry, AJ | 1 |
| Smith, SM | 1 |
| Baggett, JW | 1 |
| Swabb, EA | 1 |
| Platt, TB | 2 |
| Bosso, JA | 1 |
| Black, PG | 1 |
| Kilpatrick, M | 1 |
| Girgis, N | 1 |
| Farid, Z | 1 |
| Bishay, E | 1 |
| Constantopoulos, A | 1 |
| Thomaidou, L | 1 |
| Loupa, H | 1 |
| Papoulias, G | 1 |
| Feris, J | 1 |
| Moledina, N | 1 |
| Rodriguez, WJ | 1 |
| Khan, WN | 1 |
| Puig, J | 1 |
| Wiedermann, BL | 1 |
| Ahmad, S | 1 |
| Trujillo, H | 1 |
| Harry, N | 1 |
| Arango, A | 1 |
| Benítez, G | 1 |
| Restrepo, F | 1 |
| Mejía, GI | 1 |
| Castrillón, AL | 1 |
| Ayroza-Galvão, PA | 1 |
| Milstein-Kuschnaroff, TM | 1 |
| Mimica, IM | 1 |
| Maassen, S | 1 |
| Barbosa Júnior, SP | 1 |
| Cavalcante, NJ | 1 |
| Lorenco, R | 1 |
| Mimica, LM | 1 |
| Martino, MD | 1 |
| Strausbaugh, LJ | 1 |
| Bodem, CR | 1 |
| Laun, PR | 1 |
| Fujii, R | 1 |
| Meguro, H | 1 |
| Nishimura, T | 1 |
| Kobayashi, Y | 2 |
| Haruta, T | 2 |
| Toyonaga, Y | 1 |
| Okada, T | 2 |
| Furukawa, S | 2 |
| Kitamura, I | 1 |
| Ogura, H | 1 |
| Lebel, MH | 1 |
| McCracken, GH | 2 |
| Isani, Z | 1 |
| Rehman, N | 1 |
| Adil, N | 1 |
| el Messidi, M | 1 |
| Modai, J | 1 |
| Vittecoq, D | 1 |
| Decazes, JM | 1 |
| Wolff, M | 1 |
| Meulemans, A | 1 |
| Sakata, Y | 1 |
| Olsen, KD | 1 |
| Neu, HC | 1 |
| Greenman, RL | 1 |
| Arcey, SM | 1 |
| Dickinson, GM | 1 |
| Mokhbat, JE | 1 |
| Sabath, LD | 1 |
| Friedhoff, LT | 1 |
| Okura, K | 1 |
| Yamamoto, H | 1 |
| Kuroki, S | 1 |
2 reviews available for aztreonam and Pachymeningitis
| Article | Year |
|---|---|
The use of aztreonam in pediatric patients: a review.
Topics: Adult; Aztreonam; Bacterial Infections; Gram-Negative Aerobic Bacteria; Humans; Infant, Newborn; Men | 1991 |
Aztreonam: review of the clinical experience and potential uses in pediatrics.
Topics: Adolescent; Aztreonam; Bacterial Infections; Child; Child, Preschool; Cross Reactions; Cystic Fibros | 1988 |
16 other studies available for aztreonam and Pachymeningitis
| Article | Year |
|---|---|
Evaluation of aztreonam in experimental bacterial meningitis and cerebritis.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Encephalitis; Escherichia coli Infections; Female; Gentam | 1983 |
Penetration of aztreonam into cerebrospinal fluid of patients with and without inflamed meninges.
Topics: Adult; Anti-Bacterial Agents; Aztreonam; Chromatography, High Pressure Liquid; Female; Humans; Kinet | 1984 |
Aztreonam for treating meningitis caused by gram-negative rods.
Topics: Adult; Aztreonam; Bacterial Infections; Child; Child, Preschool; Female; Gram-Negative Bacteria; Hum | 1991 |
Successful response of severe neonatal gram-negative infection to treatment with aztreonam.
Topics: Aztreonam; Bacterial Infections; Gram-Negative Bacteria; Humans; Infant, Newborn; Infant, Premature, | 1989 |
Aztreonam in the treatment of gram-negative meningitis and other gram-negative infections.
Topics: Aztreonam; Bacterial Infections; Child; Child, Preschool; Female; Gastroenteritis; Gram-Negative Bac | 1989 |
Aztreonam in the treatment of aerobic, gram-negative bacillary infections in pediatric patients.
Topics: Abscess; Aerobiosis; Appendix; Aztreonam; Bacterial Infections; Cecal Diseases; Child, Preschool; Fe | 1989 |
Aztreonam in the treatment of bacterial meningitis.
Topics: Aztreonam; Bacterial Infections; Child, Preschool; Female; Humans; Infant; Male; Meningitis; Meningi | 1989 |
Penetration of aztreonam into cerebrospinal fluid and brain of noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa.
Topics: Animals; Aztreonam; Brain; Cerebrospinal Fluid; Meningitis; Pseudomonas aeruginosa; Pseudomonas Infe | 1986 |
[Clinical evaluation of aztreonam against pediatric purulent meningitis].
Topics: Age Factors; Aztreonam; Child; Child, Preschool; Drug Evaluation; Escherichia coli; Female; Haemophi | 1988 |
Aztreonam in the treatment of gram-negative meningitis in children.
Topics: Anti-Bacterial Agents; Aztreonam; Child, Preschool; Escherichia coli Infections; Gram-Negative Bacte | 1987 |
Penetration of aztreonam into cerebrospinal fluid of patients with bacterial meningitis.
Topics: Adult; Aged; Aztreonam; Chromatography, High Pressure Liquid; Female; Humans; Infusions, Parenteral; | 1986 |
Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Escherichia coli Infections; Male; Meningitis; Meningitis | 1985 |
Current state of infectious diseases--potential areas of directed therapy with aztreonam.
Topics: Abdomen; Anti-Bacterial Agents; Arthritis, Infectious; Aztreonam; Bacterial Infections; Biliary Trac | 1985 |
Penetration of aztreonam into human cerebrospinal fluid in the presence of meningeal inflammation.
Topics: Adult; Aged; Anti-Bacterial Agents; Aztreonam; Female; Humans; Male; Meningitis; Meningitis, Meningo | 1985 |
[Clinical evaluation on aztreonam in pediatric field and fundamental study on its penetration into cerebrospinal fluid].
Topics: Adolescent; Age Factors; Aztreonam; Bacterial Infections; Child; Child, Preschool; Drug Evaluation; | 1985 |
[Penetration of aztreonam and ampicillin to cerebrospinal fluid in the concomitant administration to rabbits with Staphylococcus aureus meningitis].
Topics: Ampicillin; Animals; Aztreonam; Drug Combinations; Injections, Intravenous; Kinetics; Meningitis; Ra | 1985 |