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aztreonam and Endocarditis, Bacterial

aztreonam has been researched along with Endocarditis, Bacterial in 3 studies

Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.

Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.

Research Excerpts

ExcerptRelevanceReference
"Aztreonam alone was bactericidal against 46% of the strains (at 16 micrograms/ml) and showed bactericidal synergy in 70%."1.27In vitro studies of investigational beta-lactams as possible therapy for Pseudomonas aeruginosa endocarditis. ( Kany, RJ; Zar, FA, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobasa, WD1
Kaye, D1
Pefanis, A1
Giamarellou, H1
Karayiannakos, P1
Donta, I1
Zar, FA1
Kany, RJ1

Other Studies

3 other studies available for aztreonam and Endocarditis, Bacterial

ArticleYear
Aztreonam, cefoperazone, and gentamicin in the treatment of experimental Enterobacter aerogenes endocarditis in rabbits.
    Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Cefoperazone; Endocarditis, Bacterial; Enterobacter; Ente

1983
Efficacy of ceftazidime and aztreonam alone or in combination with amikacin in experimental left-sided Pseudomonas aeruginosa endocarditis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Amikacin; Animals; Aortic Valve; Aztreonam; Ceftazidime; Drug Resistance, Microbial; Drug Therapy, C

1993
In vitro studies of investigational beta-lactams as possible therapy for Pseudomonas aeruginosa endocarditis.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:1

    Topics: Anti-Bacterial Agents; Aztreonam; Cefsulodin; Drug Synergism; Endocarditis, Bacterial; Humans; Imipe

1985