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aztreonam and E coli Infections

aztreonam has been researched along with E coli Infections in 31 studies

Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.

Research Excerpts

ExcerptRelevanceReference
"The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic."7.69Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994)
"The penetration of aztreonam into cerebrospinal fluid was 7 to 15% and 9 to 25%, respectively, in experimental Haemophilus influenzae type b and Escherichia coli K1 meningitis."7.67Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1. ( McCracken, GH; Olsen, KD; Sakata, Y, 1985)
"Aztreonam (SQ 26,776), a new monocyclic beta-lactam agent, was compared with ampicillin, ampicillin plus chloramphenicol, and gentamicin in rabbits with experimental meningitis induced by, respectively, ampicillin-susceptible Haemophilus influenzae, ampicillin-resistant H."7.66Evaluation of aztreonam in experimental bacterial meningitis and cerebritis. ( Brodeur, JP; Foresman, P; Gratz, JC; Rodeheaver, G; Scheld, WM, 1983)
"However, bacteriological recurrence, related to the persistent nature of the underlying disease, occurred in 6 of the 10 patients during the 1-month follow-up period."6.65Clinical experience with aztreonam in urinary and respiratory tract infections. ( Donohoe, JF; Hollingsworth, JA; Hone, R; Keelan, PJ, 1984)
"The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic."3.69Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994)
" The protective effect of cefotaxime, aztreonam and gentamicin in peritonitis induced by E."3.67Effect of Bacteroides fragilis on mortality induced by Escherichia coli in an experimental infection treated with cefotaxime, aztreonam or gentamicin. ( Castilla, C; Ponte, C; Santamaría, M; Soriano, F, 1989)
"The penetration of aztreonam into cerebrospinal fluid was 7 to 15% and 9 to 25%, respectively, in experimental Haemophilus influenzae type b and Escherichia coli K1 meningitis."3.67Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1. ( McCracken, GH; Olsen, KD; Sakata, Y, 1985)
"Aztreonam (SQ 26,776), a new monocyclic beta-lactam agent, was compared with ampicillin, ampicillin plus chloramphenicol, and gentamicin in rabbits with experimental meningitis induced by, respectively, ampicillin-susceptible Haemophilus influenzae, ampicillin-resistant H."3.66Evaluation of aztreonam in experimental bacterial meningitis and cerebritis. ( Brodeur, JP; Foresman, P; Gratz, JC; Rodeheaver, G; Scheld, WM, 1983)
"However, bacteriological recurrence, related to the persistent nature of the underlying disease, occurred in 6 of the 10 patients during the 1-month follow-up period."2.65Clinical experience with aztreonam in urinary and respiratory tract infections. ( Donohoe, JF; Hollingsworth, JA; Hone, R; Keelan, PJ, 1984)
" Dose-response relationships between antibiotic exposure and extended-spectrum-beta-lactamase-producing or AmpC-producing isolates were not demonstrated."1.43Previous Antibiotic Exposure Increases Risk of Infection with Extended-Spectrum-β-Lactamase- and AmpC-Producing Escherichia coli and Klebsiella pneumoniae in Pediatric Patients. ( Adler, AL; Elward, A; Haaland, W; Kronman, MP; Miles-Jay, A; Newland, JG; Qin, X; Weissman, SJ; Zaoutis, T; Zerr, DM; Zhou, C, 2016)
" A humanized aztreonam dose of 2 g every 6 h (1-h infusion) was evaluated alone and in combination with avibactam at 375 or 600 mg every 6 h (1-h infusion), targeting the percentage of the dosing interval in which free-drug concentrations remained above the MIC (fT>MIC)."1.39Human simulated studies of aztreonam and aztreonam-avibactam to evaluate activity against challenging gram-negative organisms, including metallo-β-lactamase producers. ( Crandon, JL; Nicolau, DP, 2013)
"The minimum dosage of antibiotics which reduced mortality in rats intraperitoneally inoculated with an Escherichia coli isolate was determined."1.27In vivo significance of the inoculum effect of antibiotics on Escherichia coli. ( Castilla, C; Fernández-Roblas, R; Ponte, C; Santamaría, M; Soriano, F, 1988)
"Carumonam was intermediate between ceftazidime and aztreonam as to the activity against Pseudomonas aeruginosa."1.27Antibacterial properties of carumonam (Ro 17-2301, AMA-1080), a new sulfonated monocyclic beta-lactam antibiotic. ( Angehrn, P, 1985)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's11 (35.48)18.2507
2000's0 (0.00)29.6817
2010's6 (19.35)24.3611
2020's5 (16.13)2.80

Authors

AuthorsStudies
Bitew, A1
Bati, S1
Bigaud, M1
Rudolph, B1
Briard, E1
Beerli, C1
Hofmann, A1
Hermes, E1
Muellershausen, F1
Schubart, A1
Gardin, A1
Hed, S1
Matlov Kormas, R1
Shashar, S1
Malyugin, BE1
Boyko, M1
Knyazer, B1
Nguyen Truong, G1
Hoang Vinh, L1
Huynh Thu, S1
Nguyen Thi Hong, P1
Nguyen Quang, B1
White, MG1
Szczepaniak Sloane, R1
Witt, RG1
Reuben, A1
Gaudreau, PO1
Andrews, MC1
Feng, N1
Johnson, S1
Class, CA1
Bristow, C1
Wani, K1
Hudgens, C1
Nezi, L1
Manzo, T1
De Macedo, MP1
Hu, J2
Davis, R1
Jiang, H1
Prieto, P1
Burton, E1
Hwu, P1
Tawbi, H1
Gershenwald, J1
Lazar, AJ1
Tetzlaff, MT1
Overwijk, W1
Woodman, SE1
Cooper, ZA1
Marszalek, JR1
Davies, MA1
Heffernan, TP1
Wargo, JA1
Jha, V1
Purohit, H1
Dafale, NA1
Moursi, AS1
El-Fishawy, N1
Djahel, S1
Shouman, MA1
Li, C1
Yu, L1
Jiang, Y1
Cui, Y1
Liu, Y1
Shi, K1
Hou, H1
Liu, M1
Zhang, W2
Zhang, J1
Zhang, C1
Chen, M3
Lu, L1
Zheng, P1
Wu, Z1
Chen, X1
Parisi, A1
Cortellini, A1
Venditti, O1
Filippi, R1
Salvatore, L1
Tortora, G1
Ghidini, M1
Nigro, O1
Gelsomino, F1
Zurlo, IV1
Fulgenzi, C1
Lombardi, P1
Roselló Keränen, S1
Depetris, I1
Giampieri, R1
Morelli, C1
Di Marino, P1
Di Pietro, FR1
Zanaletti, N1
Vitale, P1
Garajova, I1
Spinelli, GP1
Zoratto, F1
Roberto, M1
Petrillo, A1
Aimar, G1
Patruno, L1
D'Orazio, C1
Ficorella, C1
Ferri, C1
Porzio, G1
Carinato, H1
Burgy, M1
Ferry, R1
Fischbach, C1
Kalish, M1
Guihard, S1
Brahimi, Y1
Flesch, H1
Bronner, G1
Schultz, P1
Frasie, V1
Thiéry, A1
Demarchi, M1
Petit, T1
Jung, AC1
Wagner, P1
Coliat, P1
Borel, C1
Yang, Y2
Tang, Z1
Ji, J1
Yang, C1
Han, B1
Wang, Y3
Guo, H1
Gao, X1
Wang, J1
Cao, J1
Zhang, B1
Topatana, W1
Li, S2
Juengpanich, S1
Lu, Z1
Cai, X1
Guan, W1
Yang, S1
Zhao, Y1
Cheng, W1
Song, X1
Yao, Y1
Xie, Y1
Du, W1
Li, J1
Chen, XF1
Fan, X1
Hou, X1
Liu, XY1
Huang, JJ1
Kang, W2
Zhang, G1
Zhang, H2
Yang, WH1
Li, YX1
Wang, JW1
Guo, DW1
Sun, ZY1
Chen, ZJ1
Zou, LG1
Du, XF1
Pan, YH1
Li, B1
He, H1
Xu, YC1
Shi, D1
Anwar, TM1
Pan, H1
Chai, W1
Xu, S1
Yue, M1
Wang, W1
Huang, S1
Zou, C1
Ding, Y1
Wang, H2
Pu, S1
Liao, Y1
Du, H1
Wang, D1
Chen, L1
Niu, S1
Harrison, MA1
Kaur, H1
Wren, BW1
Dawson, LF1
Yu, Y1
Hu, B1
Fan, H1
Lian, S1
Li, H1
Yan, X1
Wang, S1
Bai, X1
Mao, F1
Chen, Y1
Zhang, Q1
Ding, X1
Ni, B1
Xu, X1
Jin, X1
Dai, Y1
Fachler, T1
Shteyer, E1
Orlanski Meyer, E1
Shemasna, I1
Lev Tzion, R1
Rachman, Y1
Bergwerk, A1
Turner, D1
Ledder, O1
Marianeschi, SM1
Uricchio, N1
Cerri, GB1
Ghiselli, S1
Carro, C1
Albano, G1
Viola, N1
Li, Y2
Zhang, Y1
Liu, C1
Li, X1
Zhou, Q1
Sun, C2
Zhang, L2
Singh, D1
Raghunathan, V1
Dhaliwal, M1
Rastogi, N1
Chadha, R1
Yadav, SP1
Shah, M1
Han, JH1
Park, H1
Kim, HW1
Park, KB1
Zhou, J1
Huang, H1
Zhu, Q1
Wen, F1
Dong, Y1
Hu, Y1
Pan, P1
Hong, C1
Fang, L1
Poirel, L1
Ortiz de la Rosa, JM1
Sadek, M1
Nordmann, P1
Jalil, MB1
Al Atbee, MYN1
Gu, S1
Lai, J1
Zhu, X1
Ji, T1
Feng, J1
Zhao, L1
Li, Z2
Dong, L1
Hou, G1
Zhu, Y1
He, C1
Geng, H1
Pang, D1
Afsharikhah, S1
Ghanbarpour, R1
Mohseni, P1
Adib, N1
Bagheri, M1
Jajarmi, M1
Namaei, MH1
Yousefi, M1
Ziaee, M1
Salehabadi, A1
Ghannadkafi, M1
Amini, E1
Askari, P1
Crandon, JL1
Nicolau, DP1
Tian, GB1
Huang, YM1
Fang, ZL1
Qing, Y1
Zhang, XF1
Huang, X1
McWilliams, CS1
Condon, S1
Schwartz, RM1
Ginocchio, CC1
Alm, RA1
Johnstone, MR1
Lahiri, SD1
Zerr, DM1
Miles-Jay, A1
Kronman, MP1
Zhou, C1
Adler, AL1
Haaland, W1
Weissman, SJ1
Elward, A1
Newland, JG1
Zaoutis, T1
Qin, X1
Scheld, WM1
Brodeur, JP1
Gratz, JC1
Foresman, P1
Rodeheaver, G1
Hollingsworth, JA1
Donohoe, JF1
Hone, R1
Keelan, PJ1
Sawyer, RG1
Adams, RB1
Pruett, TL1
Lun, MT3
Amatucci, AM2
Raponi, G4
Filadoro, F2
Bartolazzi, A1
Fraioli, R2
Natali, PG2
Mancini, C3
Lorino, G1
Nazzari, C1
Gaeta, A1
Ilahi, OA1
Swarna, U1
Hamill, RJ1
Young, EJ1
Tullos, HS1
Soriano, F3
García-Corbeira, P1
Ponte, C3
Fernández-Roblas, R2
Gadea, I1
Cantón, R1
Morosini, MI1
Ballestero, S1
Alvarez, ME1
Escobar, H1
Máiz, L1
Baquero, F1
Moland, ES1
Sanders, CC1
Thomson, KS1
Fayed, DF1
Dahmash, NS1
Saddique, AA1
Shibl, AM1
Keller, N1
Overbeek, BP1
Rozenberg-Arska, M1
Torensma, R1
Verhoef, J1
van Ogtrop, ML1
Mattie, H1
Guiot, HF1
van Strijen, E1
Sekh, BR1
van Furth, R1
Santamaría, M2
Castilla, C2
Kafetzis, D1
Papadimitriou, G1
Stavridis, C1
Sinaniotis, C1
Papoulias, G1
Isani, Z1
Rehman, N1
Adil, N1
el Messidi, M1
Childs, SJ1
McCracken, GH1
Sakata, Y1
Olsen, KD1
Angehrn, P1

Reviews

1 review available for aztreonam and E coli Infections

ArticleYear
Concomitant crystal and septic arthritis.
    Orthopedics, 1996, Volume: 19, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Gouty; Arthritis, Infectious; Aztreonam; Escherichia coli

1996

Trials

3 trials available for aztreonam and E coli Infections

ArticleYear
Clinical experience with aztreonam in urinary and respiratory tract infections.
    Current medical research and opinion, 1984, Volume: 9, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Aztreonam; Clinical Trials as Topic; Escherichia coli Infections

1984
Evaluation of aztreonam in the treatment of serious gram-negative infections in a university hospital in Saudi Arabia.
    Journal of chemotherapy (Florence, Italy), 1992, Volume: 4, Issue:3

    Topics: Acinetobacter; Acinetobacter Infections; Adult; Aztreonam; Bacteremia; Citrobacter; Cross Infection;

1992
Aztreonam in the treatment of urinary tract infection.
    The American journal of medicine, 1985, Feb-08, Volume: 78, Issue:2A

    Topics: Anti-Bacterial Agents; Aztreonam; Cefamandole; Cross Infection; Drug Resistance, Microbial; Escheric

1985

Other Studies

27 other studies available for aztreonam and E coli Infections

ArticleYear
    SAGE open medicine, 2021, Volume: 9

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Protozoan; Antifungal Agents; Auranofin; Azabicyclo Comp

2021
Impact of Acquired Broad-Spectrum β-Lactamases on Susceptibility to Cefiderocol and Newly Developed β-Lactam/β-Lactamase Inhibitor Combinations in Escherichia coli and Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2022, 04-19, Volume: 66, Issue:4

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases;

2022
The prevalence of multiple drug resistance Escherichia coli and Klebsiella pneumoniae isolated from patients with urinary tract infections.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:9

    Topics: Ampicillin; Anti-Bacterial Agents; Aztreonam; Cefepime; Ceftazidime; Ceftriaxone; Ciprofloxacin; Dru

2022
Drug resistance characteristics and molecular typing of Escherichia coli isolates from neonates in class A tertiary hospitals: A multicentre study across China.
    The Journal of infection, 2022, Volume: 85, Issue:5

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Carbapenems; Cefotaxime; Child; Ciprofloxacin; Do

2022
High prevalence of β-lactam and fluoroquinolone resistance in various phylotypes of Escherichia coli isolates from urinary tract infections in Jiroft city, Iran.
    BMC microbiology, 2023, 04-22, Volume: 23, Issue:1

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Ceftazidime;

2023
First Report of Prevalence of CTX-M-15-Producing Escherichia coli O25b/ST131 from Iran.
    Microbial drug resistance (Larchmont, N.Y.), 2017, Volume: 23, Issue:7

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Cefotaxime; Ciprofloxacin; Clone Cells; Drug Resi

2017
Human simulated studies of aztreonam and aztreonam-avibactam to evaluate activity against challenging gram-negative organisms, including metallo-β-lactamase producers.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; Bacterial Proteins; beta-Lactamases

2013
CTX-M-137, a hybrid of CTX-M-14-like and CTX-M-15-like β-lactamases identified in an Escherichia coli clinical isolate.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Ceftazidime;

2014
Incidence of extended-spectrum-β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates that test susceptible to cephalosporins and aztreonam by the revised CLSI breakpoints.
    Journal of clinical microbiology, 2014, Volume: 52, Issue:7

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia col

2014
Characterization of Escherichia coli NDM isolates with decreased susceptibility to aztreonam/avibactam: role of a novel insertion in PBP3.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:5

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Com

2015
Previous Antibiotic Exposure Increases Risk of Infection with Extended-Spectrum-β-Lactamase- and AmpC-Producing Escherichia coli and Klebsiella pneumoniae in Pediatric Patients.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime;

2016
Evaluation of aztreonam in experimental bacterial meningitis and cerebritis.
    Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Encephalitis; Escherichia coli Infections; Female; Gentam

1983
Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation.
    The American surgeon, 1994, Volume: 60, Issue:11

    Topics: Abdominal Abscess; Animals; Aztreonam; Bacteroides fragilis; Bacteroides Infections; beta-Lactam Res

1994
Murine monoclonal antibody elicited with antibiotic-exposed Escherichia coli exerts protective capacity in experimental bacterial infections.
    Journal of medical microbiology, 1994, Volume: 41, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Aztreonam; Blood Bactericidal Activity; Cross Reactions; Enzyme-Lin

1994
Reactivity and protective capacity of a polyclonal antiserum derived from mice immunized with antibiotic exposed Escherichia coli.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 31, Issue:1

    Topics: Animals; Aztreonam; Escherichia coli; Escherichia coli Infections; Immune Sera; Immunization, Passiv

1993
Characterisation and protective capacity of monoclonal antibodies elicited in mice against protein epitopes of antibiotic-exposed Escherichia coli.
    Journal of medical microbiology, 1997, Volume: 46, Issue:2

    Topics: Animals; Antibodies, Bacterial; Antibodies, Monoclonal; Antibody Specificity; Antigens, Bacterial; A

1997
Correlation of pharmacodynamic parameters of five beta-lactam antibiotics with therapeutic efficacies in an animal model.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Aztreonam; Cefazolin; Cefotaxime; Disease Models, Animal

1996
Lung colonization with Enterobacteriaceae producing extended-spectrum beta-lactamases in cystic fibrosis patients.
    Pediatric pulmonology, 1997, Volume: 24, Issue:3

    Topics: Adolescent; Aztreonam; beta-Lactamases; Ceftazidime; Cystic Fibrosis; Drug Resistance, Microbial; Es

1997
Can results obtained with commercially available MicroScan microdilution panels serve as an indicator of beta-lactamase production among escherichia coli and Klebsiella isolates with hidden resistance to expanded-spectrum cephalosporins and aztreonam?
    Journal of clinical microbiology, 1998, Volume: 36, Issue:9

    Topics: Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cephalosporin Resistance; Cephalosporins; Escher

1998
Immunization of mice with antibiotic-treated Escherichia coli results in enhanced protection against challenge with homologous and heterologous bacteria.
    The Journal of infectious diseases, 1991, Volume: 163, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Blood Bactericidal Activity; Ceftriaxone; Ciprofloxacin;

1991
Comparison of the effects of aztreonam and tigemonam against Escherichia coli and Klebsiella pneumoniae in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:3

    Topics: Animals; Aztreonam; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationshi

1991
Effect of Bacteroides fragilis on mortality induced by Escherichia coli in an experimental infection treated with cefotaxime, aztreonam or gentamicin.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23, Issue:3

    Topics: Animals; Aztreonam; Bacteroides fragilis; Bacteroides Infections; Cefotaxime; Escherichia coli Infec

1989
In vivo significance of the inoculum effect of antibiotics on Escherichia coli.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1988, Volume: 7, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Cefmetazole; Cefotaxime; Cefoxitin; Cephamycins; Drug Res

1988
Treatment of pyelonephritis with aztreonam: kinetic study in children.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Aztreonam; Child; Child, Preschool; Escherichia coli Infections; Humans; Infant; Pseudomonas Infecti

1987
Aztreonam in the treatment of gram-negative meningitis in children.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Anti-Bacterial Agents; Aztreonam; Child, Preschool; Escherichia coli Infections; Gram-Negative Bacte

1987
Aztreonam therapy in experimental meningitis due to Haemophilus influenzae type b and Escherichia coli K1.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Escherichia coli Infections; Male; Meningitis; Meningitis

1985
Antibacterial properties of carumonam (Ro 17-2301, AMA-1080), a new sulfonated monocyclic beta-lactam antibiotic.
    Chemotherapy, 1985, Volume: 31, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacteria; Enterobacteriaceae; Escherichia coli Infections

1985